1.Sex-Specific Reference Intervals and AgeRelated Variations in Hematologic Parameters in Korean Adults Measured Using the Beckman Coulter DxH 900 Analyzer
Shinae YU ; Eunkyoung YOU ; Sae Am SONG ; Jeong Nyeo LEE ; Kyung Ran JUN ; Ja Young LEE
Journal of Laboratory Medicine and Quality Assurance 2025;47(1):6-13
Background:
This study established sex-specific reference intervals (RIs) for hematological parameters, including the monocyte distribution width (MDW), in Korean adults and assessed the need for separate RIs according to sex in older adults.
Methods:
Hematological parameters were measured using a DxH 900 hematology analyzer (Beckman Coulter, USA) on 328 peripheral blood samples from 124 men and 204 women aged 19–93 years.
Results:
The RIs for white blood cells, red blood cells (RBCs), Hb, Hct, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, monocyte percentage, and neutrophil, eosinophil, lymphocyte, and monocyte counts differed significantly by sex (P<0.05). Mean corpuscular volume was significantly positively associated with age, whereas RBC and platelet counts were significantly negatively correlated with age in both men and women. Age-based analysis revealed significant shifts in the RBC parameters beginning at 60 years of age in men and 70 years of age in women. The MDW did not show significant differences according to sex or age.
Conclusions
This study supports the use of sex-specific RIs and highlights the importance of considering age when interpreting results regarding hematological parameters in clinical practice.
2.Sex-Specific Reference Intervals and AgeRelated Variations in Hematologic Parameters in Korean Adults Measured Using the Beckman Coulter DxH 900 Analyzer
Shinae YU ; Eunkyoung YOU ; Sae Am SONG ; Jeong Nyeo LEE ; Kyung Ran JUN ; Ja Young LEE
Journal of Laboratory Medicine and Quality Assurance 2025;47(1):6-13
Background:
This study established sex-specific reference intervals (RIs) for hematological parameters, including the monocyte distribution width (MDW), in Korean adults and assessed the need for separate RIs according to sex in older adults.
Methods:
Hematological parameters were measured using a DxH 900 hematology analyzer (Beckman Coulter, USA) on 328 peripheral blood samples from 124 men and 204 women aged 19–93 years.
Results:
The RIs for white blood cells, red blood cells (RBCs), Hb, Hct, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, monocyte percentage, and neutrophil, eosinophil, lymphocyte, and monocyte counts differed significantly by sex (P<0.05). Mean corpuscular volume was significantly positively associated with age, whereas RBC and platelet counts were significantly negatively correlated with age in both men and women. Age-based analysis revealed significant shifts in the RBC parameters beginning at 60 years of age in men and 70 years of age in women. The MDW did not show significant differences according to sex or age.
Conclusions
This study supports the use of sex-specific RIs and highlights the importance of considering age when interpreting results regarding hematological parameters in clinical practice.
3.Sex-Specific Reference Intervals and AgeRelated Variations in Hematologic Parameters in Korean Adults Measured Using the Beckman Coulter DxH 900 Analyzer
Shinae YU ; Eunkyoung YOU ; Sae Am SONG ; Jeong Nyeo LEE ; Kyung Ran JUN ; Ja Young LEE
Journal of Laboratory Medicine and Quality Assurance 2025;47(1):6-13
Background:
This study established sex-specific reference intervals (RIs) for hematological parameters, including the monocyte distribution width (MDW), in Korean adults and assessed the need for separate RIs according to sex in older adults.
Methods:
Hematological parameters were measured using a DxH 900 hematology analyzer (Beckman Coulter, USA) on 328 peripheral blood samples from 124 men and 204 women aged 19–93 years.
Results:
The RIs for white blood cells, red blood cells (RBCs), Hb, Hct, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, monocyte percentage, and neutrophil, eosinophil, lymphocyte, and monocyte counts differed significantly by sex (P<0.05). Mean corpuscular volume was significantly positively associated with age, whereas RBC and platelet counts were significantly negatively correlated with age in both men and women. Age-based analysis revealed significant shifts in the RBC parameters beginning at 60 years of age in men and 70 years of age in women. The MDW did not show significant differences according to sex or age.
Conclusions
This study supports the use of sex-specific RIs and highlights the importance of considering age when interpreting results regarding hematological parameters in clinical practice.
4.Sex-Specific Reference Intervals and AgeRelated Variations in Hematologic Parameters in Korean Adults Measured Using the Beckman Coulter DxH 900 Analyzer
Shinae YU ; Eunkyoung YOU ; Sae Am SONG ; Jeong Nyeo LEE ; Kyung Ran JUN ; Ja Young LEE
Journal of Laboratory Medicine and Quality Assurance 2025;47(1):6-13
Background:
This study established sex-specific reference intervals (RIs) for hematological parameters, including the monocyte distribution width (MDW), in Korean adults and assessed the need for separate RIs according to sex in older adults.
Methods:
Hematological parameters were measured using a DxH 900 hematology analyzer (Beckman Coulter, USA) on 328 peripheral blood samples from 124 men and 204 women aged 19–93 years.
Results:
The RIs for white blood cells, red blood cells (RBCs), Hb, Hct, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, monocyte percentage, and neutrophil, eosinophil, lymphocyte, and monocyte counts differed significantly by sex (P<0.05). Mean corpuscular volume was significantly positively associated with age, whereas RBC and platelet counts were significantly negatively correlated with age in both men and women. Age-based analysis revealed significant shifts in the RBC parameters beginning at 60 years of age in men and 70 years of age in women. The MDW did not show significant differences according to sex or age.
Conclusions
This study supports the use of sex-specific RIs and highlights the importance of considering age when interpreting results regarding hematological parameters in clinical practice.
5.Sex-Specific Reference Intervals and AgeRelated Variations in Hematologic Parameters in Korean Adults Measured Using the Beckman Coulter DxH 900 Analyzer
Shinae YU ; Eunkyoung YOU ; Sae Am SONG ; Jeong Nyeo LEE ; Kyung Ran JUN ; Ja Young LEE
Journal of Laboratory Medicine and Quality Assurance 2025;47(1):6-13
Background:
This study established sex-specific reference intervals (RIs) for hematological parameters, including the monocyte distribution width (MDW), in Korean adults and assessed the need for separate RIs according to sex in older adults.
Methods:
Hematological parameters were measured using a DxH 900 hematology analyzer (Beckman Coulter, USA) on 328 peripheral blood samples from 124 men and 204 women aged 19–93 years.
Results:
The RIs for white blood cells, red blood cells (RBCs), Hb, Hct, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, monocyte percentage, and neutrophil, eosinophil, lymphocyte, and monocyte counts differed significantly by sex (P<0.05). Mean corpuscular volume was significantly positively associated with age, whereas RBC and platelet counts were significantly negatively correlated with age in both men and women. Age-based analysis revealed significant shifts in the RBC parameters beginning at 60 years of age in men and 70 years of age in women. The MDW did not show significant differences according to sex or age.
Conclusions
This study supports the use of sex-specific RIs and highlights the importance of considering age when interpreting results regarding hematological parameters in clinical practice.
6.A Rare Case of Thoracic Intradural Epidermoid Cyst after Spinal Cord Stimulator Insertion: A Case Report
Sun Ha MIN ; Ji Hae LEE ; Jae Hyung KIM ; Myeong Ja JEONG ; Soung Hee KIM ; Ji-Young KIM ; Mi-jin KANG
Journal of the Korean Radiological Society 2022;83(4):938-944
Spinal epidermoid cysts are extremely rare benign tumors and can be congenital or acquired.Acquired spinal epidermoid cysts are found in the lumbosacral region. To our knowledge, no case of epidermoid cyst related to spinal cord stimulator insertion has yet been reported. We report the MRI findings of a rare case of thoracic intradural epidermoid cyst acquired after spinal cord stimulator insertion in a 50-year-old female.
7.Primary Breast Carcinoma with Neuroendocrine Features: Imaging Features on Mammography and Ultrasonography
Ji Eun KIM ; Ji Young KIM ; Soung Hee KIM ; Kyung Eun BAE ; Ji Hae LEE ; Mi Jin KANG ; Myeong Ja JEONG ; Soo Hyun KIM ; Kyeongmee PARK
Journal of the Korean Radiological Society 2019;80(1):129-134
Primary breast carcinoma with neuroendocrine features is an extremely rare and underrecognized subtype of the breast carcinoma. And up to present, its biologic behavior, the most effective treatment, and prognosis are not well recognized. To diagnose this rare entity, special tumor stains of neuroendocrine markers are required, which are not routinely used. The imaging features of primary breast carcinoma with neuroendocrine features (BCNF) have not been accurately described due to the extreme rarity of this tumor type. We report the imaging features in a case of BCNF, with imaging findings different from the typical imaging findings of invasive breast carcinoma.
8.Mixed Adenoneuroendocrine Carcinoma of the Small Bowel in a Patient with Crohn's Disease: A Case Report
Kwang Min KIM ; Kyung Eun BAE ; Jae Hyung KIM ; Myeong Ja JEONG ; Soung Hee KIM ; Ji Young KIM ; Soo Hyun KIM ; Jihae LEE ; Mi Jin KANG ; Tae Gyu KIM
Journal of the Korean Radiological Society 2019;80(4):793-797
Mixed adenoneuroendocrine carcinoma (MANEC) is a rare tumor of the gastrointestinal tract that has both exocrine and neuroendocrine components. There are only 5 case reports about this combined tumor in the small bowel, arose in a background of long-standing Crohn's disease. Here, we report a case of small bowel MANEC in a 54-year-old male with Crohn's disease, who presented a heterogeneous enhancing, asymmetric small bowel wall thickening with small bowel obstruction and had a difficulty in differential diagnosis before surgery.
9.Extraskeletal Ewing's Sarcoma of the Thoracic Nerve Root: A Case Report
Jung Won KIM ; Jihae LEE ; Jae Hyung KIM ; Myeong Ja JEONG ; Soung Hee KIM ; Ji Young KIM ; Soo Hyun KIM ; Mi Jin KANG ; Tae gyu KIM ; Kyung Eun BAE ; Jun Jae SHIN ; Hyun Jung KIM ; Jung Yeon KIM
Journal of the Korean Radiological Society 2019;80(3):568-573
Extraskeletal Ewing's sarcoma (EES) is a rare malignant soft tissue tumor which is morphologically indistinguishable from skeletal ES. EES usually occurs in young adults and children and there has been only one case reported in a patient aged over 70 years old. We report a case of an EES arising from the first thoracic spinal nerve root in a 73-year-old female, which was misdiagnosed as benign nerve sheath tumor in preoperative imaging evaluation.
10.Isolated Myxoma in the External Auditory Canal: A Case Report
Ah Reum PARK ; Tae Gyu KIM ; Hyun Jung KIM ; Woo Ho CHO ; Jae Hyung KIM ; Myeong Ja JEONG ; Soung Hee KIM ; Ji Young KIM ; Soo Hyun KIM ; Mi Jin KANG ; Ji Hae LEE ; Kyung Eun BAE
Journal of the Korean Radiological Society 2018;79(2):101-105
Myxoma is a benign mesenchymal neoplasm found in the heart, bone, and other soft tissues. However, myxoma of the external auditory canal is extremely rare. Since myxoma of the external auditory canal can be manifested as a part of the Carney complex, an autosomal dominant multiple familial neoplastic disorder, correct diagnosis and thorough investigation is important. We report a case of a 59-year-old man who presented to hospital with a complaint of growing mass within the right external auditory canal during one month. The surgical excision was done, and the histopathological examination revealed myxoma. In this article, we report the magnetic resonance imaging and computed tomography findings of the myxoma of the external auditory canal and correlate with the histopathological finding.

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