1.Serum Insulin-like Growth Factor Binding Proteins Profiles During the Normal Oulatory Menstrual Cycle.
Korean Journal of Fertility and Sterility 1999;26(1):67-73
The insulin-like growth factor (IGF)s are believed to one of several growth factors that play an adjunctive role in ovarian follicular development. These factors circulate bound to a family of IGF-binding protein (IGFBP)s. It is known that circulating IGFBPs are involved in the transport of IGFs to tissues and modulate IGFs actions at local tissue. The purposes of this study were to evaluate changes in serum IGFBPs profiles during normal ovulatory menstrual cylce and to compare serum IGFBPs profiles in periovulatory phase of between normal ovulatory menstrual cylce and controlled hyperstimulated cycle. Fasting blood samples were obtained from 15 normal healthy women throughout normal ovulatory menstural cycle and on the day of aspiration of oocyte from 10 patients undergoing ovarian hyperstimuation for in vitro fertilization-embryo transfer. Serum IGFBP-1-IGFBP-4 were measured by western ligand blot and immunoprecipitation. Serum 17beta-estradiol was determined by radioimmunoassay. Type and molecular weight of serum IGFBP did not changed during normal ovulatory menstural cycle. No significant variation in the relative proportion and level of each IGFBP was found throughout normal ovulatory menstural cyle. Also, the relative proportion and level of each IGFBP did not correlated with serum 17beta-estradiol level. There was no significant difference in the relative proportion and level of each serum IGFBP between on the day of ovulation in normal ovulatory menstrual cylce and on the day of aspiration of oocyte in controlled hyperstimulated cycle. Our data indicate that IGFBPs have regulatory functions in ovary through an paracrine and autocrine rather than endocrine mechanism during normal ovulatory menstural cycle.
Fasting
;
Female
;
Humans
;
Immunoprecipitation
;
Insulin-Like Growth Factor Binding Proteins*
;
Intercellular Signaling Peptides and Proteins
;
Menstrual Cycle*
;
Molecular Weight
;
Oocytes
;
Ovary
;
Ovulation
;
Radioimmunoassay
2.Estimation of Glomerular Filtration Rate from Plasma Creatinine and Height in Children.
Jeong Lan KIM ; Yong Hoon PARK ; Jeong Ok HAH
Yeungnam University Journal of Medicine 1988;5(1):93-100
In clinical practice, creatinine clearance (Ccr) remains the most commonly used laboratory assessment of glomerular function despite methodological and technical problems of urine collection. Schwartz et al. in 1976, reported that an accurate estimate of glomerular filtration rate (GFR) could be obtained from the simple determinations of plasma creatinine (Per) and body length (L): GFR (ml/min/1.73m2)=kL (cm)/Per (mg/100 ml), (k=constant). The subject of this study were 81 children admitted to our pediatric department from July, 1985 to June, 1987 and they were divided into three groups; group I, from 1 to 5 years old, group II, from 6 to 10 years old, group III, from 11 to 15 years old. The results were as following: 1) Measured creatinine clearance Ccr(M), ml/min/1.73m²) were 109.73±9.97 in group I, 108.26±9.02 in group II, 96.20±4.72 in group III and 105.48±5.23 in all age group. 2) Measured k(k(M)) obtained from CcrM=k Ht/Pcr were 0.49±0.03 in group I, 0.48±0.02 in group II, 0.43±0.02 in group III, and 0.47±0.02 in all age group (Ht; height). 3) Linear equations and correlation coefficient between Ht/Pcr (x) and Ccr (y) were y=0.82x-65.63 (r=0.99) in group I, y=0.61x-23.46(r=0.72) in group II, y=0.18x+54.44 (r=0.54) in group III and y=0.58x-22.13 (r=0.81) in all age group. 4) Ccr(E) was again estimated from linear equations between Ht/Pcr and Ccr(M) and k(E) was calculated with Ht/Pcr and Ccr(E) were 0.48±0.01 in group I, 0.49±0.01 in group II, 0.43±0.01 in group III and 0.47±0.00 in all age group. 5) Consistent values of k(E) and k(M) were highly significant as 95~97.5% in group I and II, 90~95% in group III and 97.5~99% in all age group. In summary, we could estimate GFR with height, plasma creatinine and measured k(k(M)) according to the age in easy and rapid way.
Child*
;
Creatinine*
;
Glomerular Filtration Rate*
;
Humans
;
Plasma*
;
Urine Specimen Collection
3.A Case of Vulvar Paget's Disease.
Byeong Seog KIM ; Jeong Won LEE ; Woo Gill JEONG ; Jae Hoon JEONG ; Jong Hee NAM
Korean Journal of Obstetrics and Gynecology 1999;42(8):1835-1838
Paget's disease is classified, according to location, as mammary or extramammary disease. Extramammary Paget's disease especially in the vulva is extremely rare. Several hundred cases have been described worldwide. Patients with Paget's disease of the vulva are usually white and postmenopausal. The cause of which remains elusive. A case of vulva Paget's disease is presented with brief review of literature.
Humans
;
Paget Disease, Extramammary
;
Vulva
4.Diagnostic Value of Immediate CT after Chemoembolization in Patients with Hepatocellular Carcinoma: Comparison with 2-3 Week Delayed CT.
Yong Hoon KIM ; Jong Hoon KIM ; Soon Joo CHA ; Gham HUR ; Myeong Seok JEONG ; Jeong Joo WOO ; Jeong Wook SEO ; Jeong Hyeok KIM
Journal of the Korean Radiological Society 1995;33(2):247-251
PURPOSE: Lipiodol CT is a important modality for the diagnosis of hepatocellular carcinoma and compared is usually performed at 2-3 week after Lipiodol injection. Therefore, we assessed and the diagnostic value and merits of immediate CT after chemoembolization from there of 2-3 week delayed Lipiodol CT. MATERIALS AND METHODS: Thirty three cases of chemoembolization which were performed both immediate CT after chemoembolization and 2-3 week delayed Lipiodol CT were reviewed retrospectively. They were divided into four grades according to pattern of lipiodol uptake by three radiologists. The diagnostic value of immediate Lipiiodol CT was compared to delayed Lipiodol CT. RESULTS: Grade 0 was two cases(3.0%) and Grade 1 was seven cases(21.2%). In the cases of Grade 2(23/33, 69.7%) tumor uptake could be dishng wished from parenchymal uptake of Lipiodol by its density and pattern. Tumor uptake showed dense and homogeneous pattern, but parenchymal uptake revealed less dense and hepatoram-like wedge shaped pattern. Lipiodol uptake of tumor in Grade 3(1/24, 3.0%) was equal to that in delayed Lipiodrl CT. Grade 3 and 2(72.7%) of the immediate Lipiodol CT were not inferior to delayed Lipiodol CT in its diagnostic value. CONCLUSION: The immediate Lipiodol CT could make rapid establishment of treatment plan and are expected to be more convenient than delayed CT for the patients.
Carcinoma, Hepatocellular*
;
Diagnosis
;
Ethiodized Oil
;
Humans
;
Retrospective Studies
5.Successful Treatment of Jesnner's Lymphocytic Infiltration of the Skin with Methotrexate.
Jeong Wan SEO ; Tae Hoon KIM ; Seung Hwan CHOI ; Ki Hoon SONG ; Ki Ho KIM
Korean Journal of Dermatology 2017;55(2):143-145
No abstract available.
Methotrexate*
;
Skin*
6.A Pathological and Immunohistochemical Study of 9 Cases of Inflammatory Fibroid Polyp.
Nam Hoon CHO ; Hyeon Joo JEONG ; Ho Guen KIM
Korean Journal of Pathology 1989;23(1):20-28
We aimed to study the clinicopathologic features of inflammatory fibroid polyp by histological and immunohistochemical methods. The materials used in this study consisted of 9 cases of inflammatory fibroid polyp: 4 in the stomach, 4 in the small intestine and 1 in the cecum. The results were as follows: Females were affected more frequently than males and the average age was 45 years(range:27-61). In cases of gastric lesion, the size tended to be smaller, the mass was mainly located along the greater curvature side of antrum, and confined to the submucosa. However inflammatory fibroid polyp of the small intestine was over 2.5 cm in size, located along the antemesenteric border, and involved the proper muscle layer. In addition, intussusception was accompanied by polyp in 2 cases of small intestinal lesions. Histologically inflammatory fibroid polyps of the stomach were characterized by prominent lymphocytic infiltration and occasional onion-skinning of stromal cells, whereas plasmocytic infiltration was prominent in those of the small intestine. Main component cells comprising this lesion were confirmed to be fibroblasts by immunohistochemistry which revealed strong reactivity to vimentin in the cytoplasm of slindle cells.
Female
;
Male
;
Humans
7.A Case of Congenital Smooth Muscle Hamartoma.
Hong Seong JEONG ; Seon Hoon KIM ; Yoo Shin LEE
Korean Journal of Dermatology 1987;25(4):535-538
Congenital smooth musele hamartomas appear at birth as hypertrichotic patches or plaques with or without hyperpigmentation. Histologic characteristic is hyperplasia of dermal smooth muscle bundles. We report a case of congenital smooth muscle harnartoma in 5-year-old female, who showed localized excessive-hairy, skin-colored patch on the lateral surface of left. elbow, which were found at birth. Biopsy specimen showed hyperpigmentation of the basal layers of epidermis, melanophages in upper dermis, and hyperplasia of smooth muscle bundles in lower dermis.
Biopsy
;
Child, Preschool
;
Dermis
;
Elbow
;
Epidermis
;
Female
;
Hamartoma*
;
Humans
;
Hyperpigmentation
;
Hyperplasia
;
Hypertrichosis
;
Muscle, Smooth*
;
Parturition
8.A study of clinical application of cultured epithelial autograft.
Sung Moon CHUNG ; Sung Hoon JEONG ; Sung Soo KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(4):594-601
No abstract available.
Autografts*
9.A Clinical Study on Children with Acute Glomerulonephritis.
Jeong Ok KIM ; Son Moon SHIN ; Yong Hoon PARK
Journal of the Korean Pediatric Society 1989;32(6):779-788
No abstract available.
Child*
;
Glomerulonephritis*
;
Humans
10.A clinical study of intussusception during infancy and childhood: influencing factors in the success rate of barium enema reduction.
Ki Hoon CHO ; Jeong Yong KIM ; Hyeon Jin CHO
Journal of the Korean Surgical Society 1991;41(2):254-258
No abstract available.
Barium*
;
Enema*
;
Intussusception*