Weaning is the process of getting babies used to food other than breast milk or formula milk. Homemade baby food is preferable, including a varied selection of foods, starting from rice porridge followed by adding meat, vegetables, and fruits as appropriate. Baby food gradually becomes solid until the age of one when the babies can eat rice without further preparation. Avoid salt till the age of one, and even thereafter try not to make the baby food salty. Start adding meat from six months, and include meat on a daily basis when the baby is growing fast. Babies can self-feed by hand at 8 months of age and then can learn how to use a spoon. If the time to start weaning is too delayed or the way of weaning is not appropriate, feeding problems may ensue, which can potentially lead to developmental problems. It is important to remind that the weaning process is not just giving baby food as a source of nutrition for growth? It is a way of building a family bond and is a starting point of nourishing a healthy eating habit.
Diet* ; Eating ; Fruit ; Hand ; Humans ; Infant ; Infant Nutritional Physiological Phenomena ; Meat ; Milk ; Milk, Human ; Vegetables ; Weaning*

No abstract available.
Mandible*

No abstract available.
Child* ; Humans ; Tuberculosis*

No abstract available.
Carcinogenesis* ; Oenothera biennis*

No abstract available.
Animals ; Euonymus* ; Mice*

No abstract available.
Animals ; Capsaicin* ; Macrophages, Peritoneal* ; Mice*

BACKGROUND: The activity of drug metabolizing enzymes and the modulation of their expression by inducers in the skin are the key factors for understanding of pharmacological and toxic effects of topically applied drugs. The role of these enzymes is of major importance, as they may contribute to determine the steady-state levels of biologically active substances. 3-Methylcholanthrene and all-trans- retinoic acid have been known to be inducers of the drug metabolizing enzymes. And all-trans- retinoic acid has many biological actions including anti-cancer effects. OBJECTIVE: The purpose of this study was to evaluate the effect of all-trans-retinoic acid on inducing the expression and modulation of genetic polymorphism of drug metabolizing enzymes as well as to estimate the role of all-trans-retinoic acid in carcinogenesis and drug interactions. METHODS: We analyzed the activities of CYP1A1(Cytochrome P450 1Al), NADPH cytochrome P450-reductase, UGT1 and GST after administration of 3-methylcholanthrene and all-trans-retinoic acid to the Sprague-Dawley male rats. We observed the inducible gene expression of CYP1A1, UGT1, GSTJt by RT-PCR and the genetic polymorphism of CYP1A1, UGT1, GSTK by PCR. RESULTS: 1. The expression of CYP1A1, NADPH cytochrome P450-reductase, UGT1 and GST was induced by 3-methylcholanthrene and all-trans-retinoic acid. That of NADPH cytochrome P450-reductase and UGT1 is pronouncedly enhanced by all-trans- retinoic acid. 2. The effects of 3-methylcholanthrene and all-trans-retinoic acid on inducing the expression of CYP1A1 and UGT1 correlated with an increase of mRNA expression levels of CYP1A1 and UGT1. The modulation of mRNA expression levels of GST was downregulated by all-trans-retinoic acid. 3. The genetic polymorphism of CYP1A1 was induced by 3-methylcholanthrene and all-trans- retinoic acid, and that of GSTM1 was not affected by the inducers. The induction of genetic polymorphism of GST was down regulated by all-trans-retinoic acid. CONCLUSION: 3-Methylcholanthrene and all-trans-retinoic acid modulate the inducible expression and genetic polymorphism of drug metabolizing enzymes differentially. All-trans-retinoic acid can modulate the metabolism of procarcinogen such as 3-methylcholanthrene by inducing drug metabolizing enzymes. Furthermore, the elucidation of the molecular mechanisms underlying the regulation of drug metabolizing enzymes by 3-methylcholanthrene, all-trans-retinoic acid and other drugs could help to understand their respective roles in drug interactions and carcinogenesis.
Animals ; Carcinogenesis ; Cytochrome P-450 CYP1A1 ; Cytochromes ; Drug Interactions ; Gene Expression* ; Humans ; Male ; Metabolism ; Methylcholanthrene ; NADP ; Polymerase Chain Reaction ; Polymorphism, Genetic ; Rats* ; Rats, Sprague-Dawley ; RNA, Messenger ; Skin* ; Tretinoin*

In the following report, we describe the case of a rapidly skeletonized corpse discovered in late summer. On the first day of September, a 57-year-old man was found almost completely skeletonized on a hill behind his house. His body lay prone, accompanied by a brush cutter at the entrance to the graveyard where his friend's parents were buried. His cap, clothes, and rubber boots were all intact and undamaged. Upon autopsy, no definite abnormalities were identified except for an old linear fracture on the frontoparietal bone. According to his friends and neighbors, he had likely died 8 or 9 days prior to the discovery of his body.
Autopsy ; Cadaver ; Friends ; Humans ; Middle Aged ; Parents ; Postmortem Changes ; Rubber ; Skeleton*

"Sikmulboncho" that is quoted several times to "Donguibogam(Medical Thesaurus of Korea)" published several times in 3 countries(Korea, China & Japan) as important data of botany study. Gapjinjache "Sikmulboncho", one of the bronze metal type, that exist our country was publicated in early Seonjo(1552-1608) era. Actually there are 3 items(Korea university collection, Asami library collection, Oksan seowon collection) of Gapjinjache Naeuiwonjabon one of the wooden type seen become publication after 1607 year. Bronze metal type composes the major part for Gapjinjabon, but wood type was also mixed much. Wooden type composes the major part for Naeuiwonjabon, while bronze type was little mixed. Bronze metal type disappears by wear class gradually to during 40 years and instead of this, used wood type was used. Foundation and base of this publication have formed in itself Eulhaejache Naeeuiwonjabon that start "Donguibogam" in process that do this way. Therefore, Naeeuiwon do not publish various medical books like a Naeeuiwonjabon suddenly in early 17th century. I can speak that is caused in experience and potential power that already publish this Gapjinjabon medical book ago by medical history.
Books/*history ; Botany/*history ; China ; History, 16th Century ; History, 17th Century ; Japan ; Korea ; Literature, Modern/*history ; *Metals ; Printing/*history ; *Wood

No Abstract Available.
Animals ; Armoracia* ; Cats* ; Horseradish Peroxidase* ; Muscles*