Secretory carcinoma of salivary gland origin is a recently described tumor that harbors a characteristic ETV6-NTRK3 translocation that is identical to secretory carcinoma of the breast. The majority of tumors were located in the parotid gland and other major salivary glands, while the minority occurred in a minor salivary gland. We present a case of a 71-year-old female who was diagnosed with low-grade salivary gland cancer presenting in the soft palate accompanying lymph node metastasis. Peroral wide excision, selective neck dissection, reconstruction with radial forearm free flap was performed. The final pathology report indicated secretory carcinoma of the soft palate. The patient was followed-up without evidence of recurrence for one year. At present, it is difficult to accurately assess prognosis and treatment for the secretory carcinoma of the minor salivary gland origin. Continuous follow-up with various cases is needed further.

Extranodal Natural Killer (NK)/T-cell lymphoma, nasal type, is a subtype of non-Hodgkin lymphoma, strongly associated with Epstein-Barr virus. Extranodal NK/T-cell lymphoma mostly affects the nasal cavity and there has been no report of the disease’s occurrence at the base of tongue. Here we report a case of 43-year-old man who presented with a diffuse ulcerative lesion at the base of tongue. Because the patient had oral bleeding, tracheostomy and lingual artery ligation was performed via a transcervical approach to control bleeding and protect the upper airway. We performed a deep biopsy through the lateral pharyngotomy approach, and finally, the patient was diagnosed with extranodal NK/T-cell lymphoma, nasal type. We report this rare case of extranodal NK/T cell lymphoma at the base of tongue with a literature review.

Secretory carcinoma of salivary gland origin is a recently described tumor that harbors a characteristic ETV6-NTRK3 translocation that is identical to secretory carcinoma of the breast. The majority of tumors were located in the parotid gland and other major salivary glands, while the minority occurred in a minor salivary gland. We present a case of a 71-year-old female who was diagnosed with low-grade salivary gland cancer presenting in the soft palate accompanying lymph node metastasis. Peroral wide excision, selective neck dissection, reconstruction with radial forearm free flap was performed. The final pathology report indicated secretory carcinoma of the soft palate. The patient was followed-up without evidence of recurrence for one year. At present, it is difficult to accurately assess prognosis and treatment for the secretory carcinoma of the minor salivary gland origin. Continuous follow-up with various cases is needed further.

Extranodal Natural Killer (NK)/T-cell lymphoma, nasal type, is a subtype of non-Hodgkin lymphoma, strongly associated with Epstein-Barr virus. Extranodal NK/T-cell lymphoma mostly affects the nasal cavity and there has been no report of the disease’s occurrence at the base of tongue. Here we report a case of 43-year-old man who presented with a diffuse ulcerative lesion at the base of tongue. Because the patient had oral bleeding, tracheostomy and lingual artery ligation was performed via a transcervical approach to control bleeding and protect the upper airway. We performed a deep biopsy through the lateral pharyngotomy approach, and finally, the patient was diagnosed with extranodal NK/T-cell lymphoma, nasal type. We report this rare case of extranodal NK/T cell lymphoma at the base of tongue with a literature review.

Acute supraglottitis is characterized by an inflammation and edema of the supraglottic region and a potential life-threatening condition because of its risk for sudden upper airway compromise. Prompt diagnosis, administration of broad spectrum antibiotics, and airway management is pivotal for reducing serious complications. In the immunocompromised host, microorganisms are more likely to elicit mucosal inflammations, thus clinicians should pay attention to those patients for prompt removal of the causes of immune disruption. Here we report a case of acute adult supraglottitis with neutropenia caused by anti-thyroid drug with a review of the related literatures.

Current therapeutic approaches for presbyphonia are generally categorized into non-invasive and surgical methods. Voice therapy is commonly chosen as initial treatment modality used to reduce maladaptive compensatory muscle behavior and to improve glottal closure. Nevertheless, in advanced cases of presbyphonia, glottal insufficiency may be aggravated, reducing the benefits of voice therapy. To manage the glottal insufficiency observed in such cases, surgical intervention is performed to medialize the vocal folds. Available surgical modalities include injection laryngoplasty and type I thyroplasty. Additionally, cutting-edge regenerative treatments, such as the injection of basic fibroblast growth factor, are under investigation internationally and show promising outcomes. This review aims to elucidate the current indications and relevance of surgical interventions for presbylarynx.

The soft palate of carcinoma limited to the uvular region is infrequent among oropharyngeal cancers. The oropharynx regulates swallowing and speech through dynamic motions. Failure to reconstruct after surgical resection of the oropharynx structure can lead to permanent velopharyngeal insufficiency. Therefore, suitable reconstruction is important in establishing proper functional outcomes while maintaining oncological safety.
We present a case of a 66-year-old male who was diagnosed with oropharynx cancer limited in the uvula accompanied by lymph node metastasis. After surgical resection, reconstruction was performed with the united arrangement of bilateral palatal mucomuscular flap and superiorly based posterior pharyngeal flap. There was no aspiration or reflux after feeding and epithelialization completely occurred after 1 month postoperatively. We report a successful case that the reconstruction with the local flap described above could preserve proper oropharyngeal function after primary surgery in small-sized oropharyngeal cancer.

Current therapeutic approaches for presbyphonia are generally categorized into non-invasive and surgical methods. Voice therapy is commonly chosen as initial treatment modality used to reduce maladaptive compensatory muscle behavior and to improve glottal closure. Nevertheless, in advanced cases of presbyphonia, glottal insufficiency may be aggravated, reducing the benefits of voice therapy. To manage the glottal insufficiency observed in such cases, surgical intervention is performed to medialize the vocal folds. Available surgical modalities include injection laryngoplasty and type I thyroplasty. Additionally, cutting-edge regenerative treatments, such as the injection of basic fibroblast growth factor, are under investigation internationally and show promising outcomes. This review aims to elucidate the current indications and relevance of surgical interventions for presbylarynx.

Current therapeutic approaches for presbyphonia are generally categorized into non-invasive and surgical methods. Voice therapy is commonly chosen as initial treatment modality used to reduce maladaptive compensatory muscle behavior and to improve glottal closure. Nevertheless, in advanced cases of presbyphonia, glottal insufficiency may be aggravated, reducing the benefits of voice therapy. To manage the glottal insufficiency observed in such cases, surgical intervention is performed to medialize the vocal folds. Available surgical modalities include injection laryngoplasty and type I thyroplasty. Additionally, cutting-edge regenerative treatments, such as the injection of basic fibroblast growth factor, are under investigation internationally and show promising outcomes. This review aims to elucidate the current indications and relevance of surgical interventions for presbylarynx.

Current therapeutic approaches for presbyphonia are generally categorized into non-invasive and surgical methods. Voice therapy is commonly chosen as initial treatment modality used to reduce maladaptive compensatory muscle behavior and to improve glottal closure. Nevertheless, in advanced cases of presbyphonia, glottal insufficiency may be aggravated, reducing the benefits of voice therapy. To manage the glottal insufficiency observed in such cases, surgical intervention is performed to medialize the vocal folds. Available surgical modalities include injection laryngoplasty and type I thyroplasty. Additionally, cutting-edge regenerative treatments, such as the injection of basic fibroblast growth factor, are under investigation internationally and show promising outcomes. This review aims to elucidate the current indications and relevance of surgical interventions for presbylarynx.