Neuroschistosomiasis is a serious complication of schistosomiasis, where Schistosoma parasites migrate to the central nervous system. It is often overlooked but can cause significant neurological symptoms. We present a 10-year-old male with headache and papilledema, emphasizing the importance of considering neuroschistosomiasis in patients with neurological symptoms and a history of schistosomiasis exposure. Early diagnosis and timely treatment with antischistosomal drugs and corticosteroids are crucial for positive outcomes. Raising awareness and implementing appropriate management approaches can improve the prognosis of neuroschistosomiasis.
Neuroschistosomiasis

Myelin oligodendrocyte glycoprotein associated disease (MOG-AD) is an inflammatory disorder of the central nervous system characterized by immune-mediated demyelination. We present a case of a patient with subacute to chronic progressive bilateral motor weakness associated with encephalopathy, which led to the diagnosis of MOG-AD. This case highlights the importance of recognizing the diverse clinical manifestations and the need for a multidisciplinary approach in the diagnosis and management of MOG-AD. In this review, we discuss the pathophysiology, diagnostic criteria, imaging findings, treatment strategies, and prognosis of MOG-AD based on the available literature.
Myelin-Oligodendrocyte Glycoprotein