OBJECTIVEA survey on cancer patients at the community level in Shanghai was performed, in order to study the factors affecting the quality of life (QOL) on them.

METHODSTo evaluate the QOL of cancer patients, self-administered Functional Assessment of Cancer Therapy-General (FACT-G) questionnaire and personal interview methods were used. Data analysis was performed by SPSS software (SPSS,Chicago, IL), including one-way ANOVA and linear regression methods.

RESULTSThere were 7580 valid questionnaires retrieved. Many factors were certificated to have significant relationship with QOL of cancer patients,such as family incomes, education, occupation, awareness of disease, physical exercise, cost of health care and pain (P < 0.01). Some factors however, only affecting certain aspects of the QOL, of which age, marriage state, type of tumor and stage were also noticed. KPS had strong Linear correlation with every aspect of FACT-G (P < 0.000).

CONCLUSIONPatients having a poor KPS, metastasis, low educational level, divorced or lost of spouse, pain, poor income, little exercise and old age would tend to have a poor QOL outcome.

Adult ; China ; Demography ; Female ; Health Surveys ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Neoplasms ; pathology ; physiopathology ; Quality of Life ; Residence Characteristics ; statistics & numerical data ; Young Adult

Objective To explore the relationship between the lymph node metastasis and clinicopathological features in patients with clinical stage T1a non-small cell lung cancer ( NSCLC ) . Methods Clinicopathological data of a total of 418 patients who underwent lobectomy and systematic lymph node dissection were retrospectively analyzed.Logistic regression was used to analyze the relationship between lymph node metastasis and clinicopathological features.Resulst Lymph node metastasis was observed in 25 patients.There were 122 patients who were diagnosed as ground glass opacity with no lymph node metastasis.399 patients had subcarinal dissection, among them 7 patients were found to have lymph node metastasis.Univariate analysis showed that gender, smoking history, diameter of lymph node, ground glass opacity ( GGO ) , differentiation of the tumor and tumor site were the factors affecting lymph node metastasis ( all P<0.05) .Logistic regression analysis showed that diameter of lymph node, differentiation of the tumor and the site of lesion were independent risk factors for lymph node metastasis of NSCLC. Conclusions Tumor in the left lung, poor differentiation, and diameter of lymph nodes ≥1 cm on the preoperative CT image are independent risk factors for lymph node metastasis of NSCLC, hence we should pay attention before surgery and systematic lymph node dissection should be done.For patients with poor differentiation and lymph nodes≥1 cm, subcarinal lymph nodes dissection is recommended for the sake of higher possibility of lymph node metastasis.For patients with ground glass opacity≤2 cm, the lymph node metastasis is extremely rare, therefore, selective lymph node dissection is reconmmended.

Objective To explore the relationship between the lymph node metastasis and clinicopathological features in patients with clinical stage T1a non-small cell lung cancer ( NSCLC ) . Methods Clinicopathological data of a total of 418 patients who underwent lobectomy and systematic lymph node dissection were retrospectively analyzed.Logistic regression was used to analyze the relationship between lymph node metastasis and clinicopathological features.Resulst Lymph node metastasis was observed in 25 patients.There were 122 patients who were diagnosed as ground glass opacity with no lymph node metastasis.399 patients had subcarinal dissection, among them 7 patients were found to have lymph node metastasis.Univariate analysis showed that gender, smoking history, diameter of lymph node, ground glass opacity ( GGO ) , differentiation of the tumor and tumor site were the factors affecting lymph node metastasis ( all P<0.05) .Logistic regression analysis showed that diameter of lymph node, differentiation of the tumor and the site of lesion were independent risk factors for lymph node metastasis of NSCLC. Conclusions Tumor in the left lung, poor differentiation, and diameter of lymph nodes ≥1 cm on the preoperative CT image are independent risk factors for lymph node metastasis of NSCLC, hence we should pay attention before surgery and systematic lymph node dissection should be done.For patients with poor differentiation and lymph nodes≥1 cm, subcarinal lymph nodes dissection is recommended for the sake of higher possibility of lymph node metastasis.For patients with ground glass opacity≤2 cm, the lymph node metastasis is extremely rare, therefore, selective lymph node dissection is reconmmended.