1.Immunohistochemical study of caveolin-1 and -2 in the rat retina.
Heechul KIM ; Taeki LEE ; Jeeyoung LEE ; Meejung AHN ; Changjong MOON ; Myung Bok WIE ; Taekyun SHIN
Journal of Veterinary Science 2006;7(2):101-104
The expression of caveolin-1 and -2 in the retina was examined; Western blot analysis showed that both were present. Immunohistochemistry indicated that caveolin-1 was expressed in the majority of retinal layers, including the ganglion cell layer, inner plexiform layer, outer plexiform layer, and in the vascular endothelial cells of the retina. Caveolin-2 was primarily immunostained in the vessels, but in a few other elements as well. This is the first demonstration of caveolin differential expression in the retina of rats, and suggests that caveolin plays an important role in signal transduction in glial cells and neuronal cells.
Animals
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Caveolin 1/*analysis/immunology
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Caveolin 2/*analysis/immunology
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Gene Expression Regulation
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Immunohistochemistry
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Male
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Rats
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Rats, Sprague-Dawley
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Retina/*chemistry
2.Subconjunctival Abscess Formation with Periorbital Cellulitis Following Scleral Buckling
Jeeyoung KWAK ; Dong Cheol LEE ; Ji Hye JANG
Journal of the Korean Ophthalmological Society 2022;63(9):802-806
Purpose:
We present a case of a subconjunctival abscess formation with periorbital cellulitis following scleral buckling (SB) and pars planar vitrectomy (PPV).Case summary: A 51-year-old female patient came to our hospital with complaints of ocular pain and discharge in the right eye. The patient underwent SB and several times of PPV for multiple rhegmatogenous retinal detachment due to acute retinal necrosis. The onset of symptoms was 9 months after the last vitrectomy. A subconjunctival abscess was seen at 8 o'clock position on slit lamp, and periorbital cellulitis was observed on computed tomography image, the patient underwent an incision and drainage (I&D) surgery. Another 9 months later, a subconjunctival abscess was newly found at 4 o'clock position. Since the abscess site and the position of the stitch which sutured the buckle sponge was exactly same, the cause of infection was thought to be the sponge suture materials. Along with I&D surgery, the suture at the end of the sponge was removed. After then, conjunctival and periorbital inflammation got improved and the patient is still in the process of examination to date.
Conclusions
Subconjunctival abscess or periorbital cellulitis is a rare complication of SB, caused by the use of an exogenous materials such as silicon sponge or suture stitches. Therefore, when ocular pain or inflammation is observed in SB patients, early detection and active treatment is required for suspected periorbital cellulitis.
3.Correlation between Thyroid-stimulating Antibody Level Change and Extraocular Muscle Thickness Change in Thyroid Eye Disease
Jeeyoung KWAK ; Dong Cheol LEE
Journal of the Korean Ophthalmological Society 2021;62(10):1315-1323
Purpose:
To investigate the changes in extraocular muscle thicknesses by variations in the thyroid stimulating antibody (TSAb) level in patients with thyroid eye disease (TED).
Methods:
A total of 67 TED patients were enrolled. They were divided into two groups: an experimental group with clinically significant elevated TSAb levels (≥140 IU/L) and a control group (TSAb <140 IU/L). All of the lateral, medial, superior, and inferior rectus muscle thicknesses were measured with the aid of anterior segment optical coherence tomography (OCT). The average thicknesses for both eyes were recorded for each patient based on the values measured at the ends of the muscles (which become vertically thinner from the points of tendon attachment). We measured changes in TSAb levels and extraocular muscle thicknesses after two follow-up periods and sought correlations among these parameters.
Results:
At the initial visits, the inferior rectus muscle thickness was positively correlated with the TSAb level in the experimental group (p = 0.045, r = 0.478). None of the medial, superior, or lateral rectus muscle thicknesses were so correlated. On follow-up, the variation in TSAb level correlated negatively with changes in lateral rectus muscle thickness (p = 0.038, r = -0.357). The superior rectus muscle thickness tended to be negatively correlated with the TSAb level, but statistical significance was not attained (p = 0.146, r = -0.669). The thicknesses of the inferior and superior rectus muscles did not change over time.
Conclusions
In TED patients, TSAb variations seem to reflect the extent of periorbital tissue edema, thus correlating negatively with especially lateral rectus muscle thickness changes.
5.Comparison of Physicians' and Patients' Perception on the Effect of Internet Health Information.
Jeongeun KIM ; Sunyoung LEE ; Sunyoung PARK ; Meihua PIAO ; Jeeyoung JOO ; Sukwha KIM
Journal of Korean Society of Medical Informatics 2009;15(4):373-379
OBJECTIVE: To determine the differences between the patient's and physicians' views of the effects of internet health information on the physician-patient relationship. METHODS: An online survey was carried out with 25 items developed by revising the questionnaire of Direct-to-Consumer Advertising to accommodate the internet health information. The respondents were 671 patients who were active participants in online patient communities and 493 physicians who were the professors of medical schools and practicing physicians. RESULTS: Most of the patients were positive toward the Internet Health Information saying that it gives them advice from a doctor with self-confidence, allows them to follow their doctor's directions well, obtain more medical treatment after retrieving the information, etc. In contrast, physicians perceived that the internet health information may have variety of negative effects, such as increasing the healthcare cost, unnecessary clinic visits and undermining of the doctor-patient relationship. There were significant differences in the perspectives between the physicians and patients. CONCLUSION: It will be necessary to ensure experts provide internet health information, which will have beneficial effects on the quality of care, physician-patient relationship, and health service utilization.
Ambulatory Care
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Surveys and Questionnaires
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Dietary Sucrose
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Health Care Costs
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Health Services
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Humans
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Internet
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Schools, Medical
6.Acute Intermittent Porphyria Presenting with Periodic Leg Pain.
Hye Jin LEE ; Soojeong KIM ; Jeeyoung OH
Journal of the Korean Neurological Association 2017;35(1):53-54
No abstract available.
Leg*
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Porphyria, Acute Intermittent*
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Porphyrias
7.Usage of the Internet of Things in Medical Institutions and its Implications
Hyoun-Joong KONG ; Sunhee AN ; Sohye LEE ; Sujin CHO ; Jeeyoung HONG ; Sungwan KIM ; Saram LEE
Healthcare Informatics Research 2022;28(4):287-296
Objectives:
The purpose of this study was to explore new ways of creating value in the medical field and to derive recommendations for the role of medical institutions and the government.
Methods:
In this paper, based on expert discussion, we classified Internet of Things (IoT) technologies into four categories according to the type of information they collect (location, environmental parameters, energy consumption, and biometrics), and investigated examples of application.
Results:
Biometric IoT diagnoses diseases accurately and offers appropriate and effective treatment. Environmental parameter measurement plays an important role in accurately identifying and controlling environmental factors that could be harmful to patients. The use of energy measurement and location tracking technology enabled optimal allocation of limited hospital resources and increased the efficiency of energy consumption. The resulting economic value has returned to patients, improving hospitals’ cost-effectiveness.
Conclusions
Introducing IoT-based technology to clinical sites, including medical institutions, will enhance the quality of medical services, increase patient safety, improve management efficiency, and promote patient-centered medical services. Moreover, the IoT is expected to play an active role in the five major tasks of facility hygiene in medical fields, which are all required to deal with the COVID-19 pandemic: social distancing, contact tracking, bed occupancy control, and air quality management. Ultimately, the IoT is expected to serve as a key element for hospitals to perform their original functions more effectively. Continuing investments, deregulation policies, information protection, and IT standardization activities should be carried out more actively for the IoT to fulfill its expectations.
8.Quantitative EEG Analysis in Atypical Rolandic Epilepsies of Childhood.
Jeeyoung OH ; Hyang Woon LEE ; Hyunji CHO ; Kyoung Gyu CHOI ; Kee Duk PARK ; Jeong Yeon KIM
Journal of Korean Epilepsy Society 2005;9(1):53-58
PURPOSE: Benign childhood epilepsy with centrotemporal spikes (BCECT) or benign rolandic epilepsy (BRE) is not always benign in clinical or neuroimaging features. Recent studies have reported atypical forms of rolandic epilepsy with abnormal neurologic and/or neuroimaging findings, sometimes, also with poor seizure control. We investigated whether there are any differences in linear and nonlinear EEG analysis in typical and atypical rolandic epilepsies of childhood. METHODS: Ten patients with typical BRE group and seven patients with atypical BRE group were included in this study. We selected artifact-free 10-second epochs from 19 electrodes of 10-20 international EEG system from each patient. The power spectrum was calculated in delta, theta, alpha, beta, and gamma frequency ranges. The fractal dimension was analyzed as a nonlinear EEG analysis. We analyzed both EEGs with interictal spikes and without focal slowing or epileptiform activities. RESULTS: The spectral EEG analysis showed a significant increase of absolute and relative power of delta with decrease of alpha bands in atypical BRE group compared to typical group. There was no statistical difference in fractal dimension between the two groups. CONCLUSION: Atypical BRE group showed enhanced delta and decreased alpha power, suggesting a cortical dysfunction in this group with poor clinical outcome.
Electrodes
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Electroencephalography*
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Epilepsy
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Epilepsy, Rolandic*
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Fractals
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Humans
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Neuroimaging
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Seizures
9.Differential Diagnosis for the Cause of Carpal Tunnel Syndrome Using Musculoskeletal Ultrasound.
Hae Rim KIM ; Jeeyoung OH ; Sang Heon LEE
The Journal of the Korean Rheumatism Association 2010;17(4):454-456
No abstract available.
Carpal Tunnel Syndrome
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Diagnosis, Differential
10.The Perception of the Patients on the Effects of Internet Health Information on the Doctor-Patient Relationship.
Jeongeun KIM ; Seonghee JEONG ; Meihua PIAO ; Sunyoung PARK ; Sunyoung LEE ; Jeeyoung JOO ; Sukwha KIM
Journal of Korean Society of Medical Informatics 2008;14(4):345-354
OBJECTIVES: The objective of the study was to determine patient's views of the effects of internet health information on the doctor-patient relationship. METHODS: Online survey with 26 items was conducted which was developed by revising the questionnaire of Direct-to-Consumer Advertising to accommodate to the internet health information. Members of the active online patients communities were solicited by e-mail. RESULTS: Most of them gave an affirmative answer on Internet Health Information saying that it makes them get advice from doctor with self-confidence, follow their doctor's direction well, get more medical treatment after retrieving the information and so on. By contrast, physicians perceived that internet health information may have variety of negative effects according to the preceding research. CONCLUSIONS: There are the differences of perspectives between physicians and patients. Therefore it will be necessary to make the experts' intervention in the provision of internet health information, which will have good effects on quality of care, doctor-patient relationship, and health service utilization.
Electronic Mail
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Health Services
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Humans
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Internet
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Surveys and Questionnaires