No abstract available.
Blood Group Incompatibility* ; Bromelains*

BACKGROUND: Antibody screening and identification tests are indispensable tools for protecting patients from acute hemolytic transfusion reaction. The column agglutination method has been widely used because of its simplicity and superiority to other methods for detecting warm antibodies. The purpose of this study was to analyze the frequency, distribution and clinical characteristics of unexpected antibodies found in transfusion candidates at a secondary hospital in Gyeongbuk Province, Korea. METHODS: The antibody screening tests were carried out with 9,275 sera samples using the column agglutination method from July 2009 to September 2011. The antibodies were screened and identified using the DiaMed-ID system (DiaMed, Murten, Switzerland). RESULTS: The positive rate for antibody screening tests was 0.5% (50/9,275). Unexpected antibodies were identified in 36 cases (0.4%). The most frequently detected antibody was anti-Lea in 15 cases (30%), followed by anti-Leb in 10 cases (20%) and anti-E in 8 cases (16%). Antibodies that remain unidentified were detected in 11 cases (22%). CONCLUSION: Compared with previous reports, this study demonstrated that the frequency and distribution of unexpected antibodies were no different than those found in general hospitals. This study may provide data for the frequency and characteristics of unexpected antibodies in a secondary hospital.
Agglutination ; Antibodies ; Blood Group Incompatibility ; Hospitals, General ; Humans ; Mass Screening

No abstract available.
Breast Diseases* ; Breast*

Pulmonary carcinosarcoma(Sarcomatoid carcinoma of the lung) is a rare pulmonary malignancy, which is defined as having an admixtture of both carcinomatous and sarcomatous components. Pulmonary carcinosarcoma occurs most frequentlly in males between 50 and 80 years of age. It predominantly affects the upper lobe and/or the principal bronchi, and is associated with a history of smoking. Here, we report a case of pulmonary carcinosarcoma with a left lobe atelectasis due to an endobronchial mass in a 56-year-old male. After a left pneumonectomy, the pathologic stage was IIb (T3N0M0). Four months later, an abdominal mass was observed and exploratory laparotomy revealed metastases of the pulmonary carcinosarcoma to the pelvic cavity.
Bronchi ; Carcinosarcoma* ; Humans ; Laparotomy ; Male ; Middle Aged ; Neoplasm Metastasis ; Pneumonectomy* ; Pulmonary Atelectasis ; Smoke ; Smoking

Bethanechol, a cholinergic agonist, has been recommended for the management of peripheral anticholinergic side effects during the treatment of antipsychotic medications. But there have been few studies which have evaluated the drug interactions of antipsychotics and bethanechol, even the treatment effects of bethanechol on anticholinergic side effects. So the authors have evaluated whether psychopathology and plasma haloperidol and reduced haloperidol concentrations are significantly changed or not when bethanechol was administrated with maintained doses of haloperidol and other coadministrated drugs(such a benztropine). Also we have evaluated the abating effects of bethanechol on anticholinergic side effects during the treatment with haloperidol. Fifteen schizophrenics with higher than 5 of total score of anticholinergic side effects of 'Rating scale for side effect' were assigned to two groups, and bethanechol 30mg/day and 60mg/day were applied on each group for 4 weeks. The daily haloperidol dosages were fixed before 2 weeks of study. We assessed anticholinergic side effects by 'Rating scale for side effect' and psychopathology by BPRS, and plasma haloperidol and reduced haloperidol concentrations by HPLC at baseline, 2nd week and 4th week. The results were as followed. 1) There was no significant change of plasma haloperidol and reduced haloperidol concentration. 2) At baseline, the dosage of haloperidol showed significant correlation with the total score of anticholinergic side effect, but not at 2nd week and 4th week. 3) In 60mg/day group, dry mouth and the total score of anticholinergic side effects were significantly improved, but not in 30mg/day group. 4) There was no significant change of BPRS except withdrawal at 2nd week. These results suggest that coadministration of bethanechol influenced neither on psychopathology nor on plasma haloperidol and reduced haloperidol concentrations and that improved dry mouth and total score of anticholinergic side effects at 60mg/day.
Antipsychotic Agents ; Bethanechol* ; Cholinergic Agonists ; Chromatography, High Pressure Liquid ; Drug Interactions ; Haloperidol* ; Mouth ; Plasma* ; Psychopathology ; Schizophrenia

No abstract available.
Anemia, Megaloblastic* ; Humans ; Megaloblasts* ; Methotrexate*

No abstract available.
Child* ; Hip* ; Humans ; Osteoma, Osteoid*

No abstract available.

Kerion celsi, a severe inflammatory type of tinea capitis, which occurs chiefly in children between the ages of 4 and 14 years. We report a case of kerion celsi occuring in an elderly woman. She is a 67-year old wonman, presented with inflammatory, boggy mass studded with broken hairs, and oozing purulent materials from follicular orifices on the parietal scalp, which had been extending over almost entire scalp for 2 weeks. Kerin celsi caused by M. canin with atypical microscopic findings of the colony on the Sabouraud's dextrose agar was diagnosed by PCR analysis using PAPD method. This case is reported with two interesting facts: Kerion celsi is occuring rarely in old persons; Clinically kerion celsi progessed rapidly after onset in this case.
Agar ; Aged ; Child ; Female ; Glucose ; Hair ; Humans ; Microsporum* ; Polymerase Chain Reaction ; Rabeprazole ; Scalp ; Tinea Capitis*

Methazolamide is a carbonic anhydrase inhibitor commonly used for lowering intraocular pressure in glaucoma and other ophthalmologic diseases. Carbonic anhydrase inhibitors are sulfonamide derivatives that are known to cause many adverse side effects, including dermatologic reactions. Recently, Stevens-Johnson syndrome (SJS) associated with methazolamide treatment has been reported in Japanese and Japanese Americans, and it suggested a relationship between genetic background and methazolamide-induced SJS. We report four cases of SJS induced by methazolamide. Methazolamide should be prescribed with caution in patients of Japanese or Korean descent.
Asian Americans ; Asian Continental Ancestry Group ; Carbonic Anhydrase Inhibitors ; Carbonic Anhydrases ; Glaucoma ; Humans ; Intraocular Pressure ; Methazolamide* ; Stevens-Johnson Syndrome*