1.A Clinical Study of Hospitalized Neonates with Fever.
Youn Mo AHN ; Chang Ryul KIM ; Woo Gill LEE ; Soo Jee MOON
Journal of the Korean Pediatric Society 1988;31(11):1437-1444
No abstract available.
Fever*
;
Humans
;
Infant, Newborn*
2.The pros and cons of ultrasound-guided procedures in pain medicine
The Korean Journal of Pain 2024;37(3):201-210
The application of ultrasound (US) in pain medicine has been a rapidly growing field since the 2000s. Musculoskeletal injections, peripheral nerve blocks, and neuraxial injections under US guidance have been acknowledged for managing chronic pain. Although many studies on US-guided pain procedures have been published, there needs to be a classification system to evaluate which image device, the US or fluoroscopy, is clinically and technically better in various pain interventions. Therefore, this narrative review introduces the classification system for the US-guided pain procedures according to their clinical and technical outcomes and designates US-guided pain procedures into one of the four categories by reviewing previous prospective randomized comparative trials.
3.The pros and cons of ultrasound-guided procedures in pain medicine
The Korean Journal of Pain 2024;37(3):201-210
The application of ultrasound (US) in pain medicine has been a rapidly growing field since the 2000s. Musculoskeletal injections, peripheral nerve blocks, and neuraxial injections under US guidance have been acknowledged for managing chronic pain. Although many studies on US-guided pain procedures have been published, there needs to be a classification system to evaluate which image device, the US or fluoroscopy, is clinically and technically better in various pain interventions. Therefore, this narrative review introduces the classification system for the US-guided pain procedures according to their clinical and technical outcomes and designates US-guided pain procedures into one of the four categories by reviewing previous prospective randomized comparative trials.
4.The pros and cons of ultrasound-guided procedures in pain medicine
The Korean Journal of Pain 2024;37(3):201-210
The application of ultrasound (US) in pain medicine has been a rapidly growing field since the 2000s. Musculoskeletal injections, peripheral nerve blocks, and neuraxial injections under US guidance have been acknowledged for managing chronic pain. Although many studies on US-guided pain procedures have been published, there needs to be a classification system to evaluate which image device, the US or fluoroscopy, is clinically and technically better in various pain interventions. Therefore, this narrative review introduces the classification system for the US-guided pain procedures according to their clinical and technical outcomes and designates US-guided pain procedures into one of the four categories by reviewing previous prospective randomized comparative trials.
5.A Case of Median Raphe Canal of the Penis.
Yong Joo MOON ; Seong Sin HONG ; Seok Kweon YUN ; Jee Youn WON
Korean Journal of Dermatology 2003;41(8):1097-1099
Median raphe canal is an uncommon disease and represents a defect abnormality of the male genitalia. It occurs along the ventral median raphe from the glans penis to the anus. Histologically the canal is lined by stratified squamous epithelium which dose not communicate with the urethra. Surgical excision is the treatment of choice. Recently we observed a 25-year-old male patient who had had a median raphe canal located in the ventral aspect of penis.
Adult
;
Anal Canal
;
Epithelium
;
Genitalia, Male
;
Humans
;
Male
;
Penis*
;
Urethra
6.Management of Intractable Painful Diabetic Peripheral Neuropathy: The Perspective of a Pain Specialist
Journal of Korean Diabetes 2022;23(4):230-237
Peripheral neuropathy is one of the most common complications of both type 1 and type 2 diabetes. The most common diabetic neuropathy (DN) is distal symmetric polyneuropathy, with characteristic glove- and stocking-like presentation of distal sensory or motor function loss. Because painful DN is associated with increased mortality and morbidity, early recognition and preventive measures are essential. Nevertheless, diagnosing DN or painful DN is challenging, particularly in patients with early and mild neuropathy, and there is no established gold standard. Furthermore, there is no established DN treatment other than improved glycemic control, and only symptomatic management is available for painful DN. However, thanks to health-conscious living, almost one-third of patients with painful DN derive sufficient pain relief with existing pharmacotherapies. These include antidepressants (tricyclic acid, serotonin-norepinephrine reuptake inhibitor), anticonvulsants (calcium-channel blocker, sodium channel blocker), and others (sarpogrelate). A more precise and distinct symptom profile from patients with painful DN may help identify patients more responsive to one treatment versus another. In addition to pharmacological, physical, cognitive, or educational management for painful DN, large randomized clinical trials are needed to identify the most effective minimally invasive interventions. Transcutaneous electrical nerve stimulation, pain scrambler therapy, sympathetic ganglion block, and botulinum toxin injections have been investigated as alternative therapeutic outcomes.
7.Cyclosporine in the treatment of psoriasis.
Jai YOUN ; Sang Eun MOON ; Do Won KIM ; Eui Soo PARK ; Doo Chan MOON ; Young Keun KIM ; Dong Sik BANG ; Seung Kyung HAN ; Jee Ho CHOI ; Mi Youn PARK ; Inn Ki CHUN ; Han Uk KIM
Korean Journal of Dermatology 1993;31(3):320-328
BACKGROUND: Psoriasis is belived to be a disorder of keratinocyte hyperproliferation mediated by T helper cells. Cyclosproine is one of the immunosuppressants and there have been several studies showing the benefcial effects of cyclosporine on psoriasis. OBJECTIVE: To evaluate the clinical efficacy, tolerability, and adverse effects of cyclosporine, a randomized open uncontrolled multicenter study was conducted in 15 university hospitals in Korea. METHOD: There were 68 total trial cases and among them 16 patients dropped out from the study. The reported reasons for stopping the use of the medication under study prematurely were lack of cooperation(seven cases), adverse effects(six cases), the ineffectiveness of the medication(two cases), and another(one case). The drug was administered for 18 weeks to 52 patients. The initial dosage of the drug was 2.5mg/kg/day which was maintained or increased to 4mg/kg/day or 5mg/kg/day according to the PASI score reduction rate at the 6th and 12th week. The PASI score was measured and Iaboratory tests and observation of adverse events were done. RESULTS: At the end of therapy PASI score reduction rate of more than 66% occured in 40 patients (76.9%). The PASI score was significantly reduced from 20.0 to 5.4 after treatment for 18 weeks. The social disability score was significantly decreased. Pruritus and nail involvement were also significantly decreased. The change of systolic and diastolic blood pressure were statistically not significant. The 30% increase of serum creatinine level compared to the baseline was observed in six patients(11.5%) at the 6th week, three patients(5.8%) at the 12th week, five patients(9.6%) at the 18th week, but no patients showed an increase above the normal range.The increase of serum total bilirubin and SGOT was observed in six patients(11.5%) and one patient(1.9%0, respectively. The clinical adverse events reported during the study were gastrointestinal trouble(seven cases, 13.5%), hypertrichosis(two cases, 3.8%), generalized weakness(two cases, 3.8%0, paresthesia(one case, 1.9%), hypertension(one case, 1.9%), disturbance of erection(one case, 1.9%). The overall assessment of efficacy and tolerability by investigator and patients were mostly good or very good. CONCLUSION: Generally cyclosporine was well accepted and tolerated and low dose cyclosporine therapy-2.5mg/kg/day to 5mg/kg/day-is an effective therapeutic modality for the treatment of psoriasis.
Aspartate Aminotransferases
;
Bilirubin
;
Blood Pressure
;
Creatinine
;
Cyclosporine*
;
Hospitals, University
;
Humans
;
Immunosuppressive Agents
;
Keratinocytes
;
Korea
;
Pruritus
;
Psoriasis*
;
Research Personnel
;
T-Lymphocytes, Helper-Inducer
8.Result of a Mixture with Vegimil A(50%) and a known Local Infant Formular (50%) to Premature Infants.
Keun Soo LEE ; Soo Jee MOON ; Gwi Jong CHOI ; Sang Yoon LEE ; Kyu Youp KIM ; Kee Young YOUN ; Jin Woo HAHN
Journal of the Korean Pediatric Society 1983;26(1):1-7
No abstract available.
Humans
;
Infant*
;
Infant, Newborn
;
Infant, Premature*
9.A Case of Cutaneous Manifestations Associated With Hydroxyurea Therapy.
Soo Jung JANG ; Yong Joo MOON ; Yong Ho CHOI ; Jung Hwan KIM ; Jee Youn WON
Korean Journal of Dermatology 2003;41(7):965-967
Hydroxyurea is an antitumor agent that has attained an important role in the management of myeloproliferative syndromes. Its mechanism of action is not fully understood, but it appears to affect DNA synthesis and genetic control of cell replication by inhibiting the conversion of ribonucleotides in deoxyribonucleotides. Cutaneous side effects such as xerosis, hyperpigmentation, nail changes, skin ulceration, alopecia, and palmoplantar keratoderma may occur, especially with long-term treatment. We report a case of 65-year-old chronic myelogenous leukemia(CML) patient showing various cutaneous manifestations after receiving long-term hydroxyurea therapy.
Aged
;
Alopecia
;
Deoxyribonucleotides
;
DNA
;
Humans
;
Hydroxyurea*
;
Hyperpigmentation
;
Keratoderma, Palmoplantar
;
Ribonucleotides
;
Skin Ulcer
10.A Case of Multiple Verruciform Xanthoma of Oral Cavity and Gastrointestinal tract.
Yong Ho CHOI ; Yong Ju MOON ; Yong Woong LEE ; Jee Youn WON ; Eun Sup SONG
Korean Journal of Dermatology 2002;40(2):162-165
Verruciform Xanthoma(VX) is a rare disease of unknown etiology that is typically solitary and predominantly located within the oral cavity. It is usually not associated with other lesions or metabolic abnormalities. Histologic features include acanthosis with uniform elongation of the rete ridges and xanthomatous cells that lie in are and typically confined to the papillary dermis. We report a rare case of multiple verruciform xanthoma that occurs in oral cavity and gastrointestinal tract simultaneously.
Dermis
;
Gastrointestinal Tract*
;
Mouth*
;
Rare Diseases
;
Xanthomatosis*