1.First and Early Second Trimester Diagnosis of Fetal Heart Disease.
Journal of the Korean Pediatric Cardiology Society 2002;6(2):122-126
No Abstract available.
Diagnosis*
;
Female
;
Fetal Heart*
;
Humans
;
Pregnancy
;
Pregnancy Trimester, Second*
2.New Development in Fetal Echocardiography.
Journal of the Korean Pediatric Cardiology Society 2002;6(1):16-22
No Abstract available.
Echocardiography*
3.The Role of NF-kappaB in the TNFalpha-induced Hyperplasia of Synoviocytes Isolated from Patients with Rheumatoid Arthritis.
Jee Hee YOON ; Sung Hee HWANG ; So Yeon MIN ; Ho Yeon KIM
Korean Journal of Immunology 2000;22(3):131-137
No abstract available.
Arthritis, Rheumatoid*
;
Humans
;
Hyperplasia*
;
NF-kappa B*
4.Prenatal Ultrasonography.
Journal of the Korean Pediatric Society 2001;44(12):1359-1363
No abstract available
Ultrasonography, Prenatal*
5.Pendred's Syndrome Associated with Asymmetrical Septal Hypertrophy & Severe Anemia in a Non-Treated 15-Year-Old.
Phil Soo OH ; Seong Seop KIM ; Jee Yeon MIN ; I Seok KANG ; Dong Kyu JIN ; Heung Jae LEE
Journal of Korean Society of Pediatric Endocrinology 1997;2(1):127-132
We report an extremely specific case of Pendred's syndrome, originally described with an association of thyroid organification defect and hearing impairment; normal-sized thyroid, severe hypothyroidism manifested by profoundly retarded physical and mental development, cardiomegaly and severe hypochromic & microcytic anemia associated with asymmetrical septal hypertrophy.
Adolescent*
;
Anemia*
;
Cardiomegaly
;
Hearing Loss
;
Humans
;
Hypertrophy*
;
Hypothyroidism
;
Thyroid Gland
6.Exploring the Potential of GlycolyticModulation in Myeloid-Derived Suppressor Cells for Immunotherapy and Disease Management
Jisu KIM ; Jee Yeon CHOI ; Hyeyoung MIN ; Kwang Woo HWANG
Immune Network 2024;24(3):e26-
Recent advancements in various technologies have shed light on the critical role of metabolism in immune cells, paving the way for innovative disease treatment strategies through immunometabolism modulation. This review emphasizes the glucose metabolism of myeloid-derived suppressor cells (MDSCs), an emerging pivotal immunosuppressive factor especially within the tumor microenvironment. MDSCs, an immature and heterogeneous myeloid cell population, act as a double-edged sword by exacerbating tumors or mitigating inflammatory diseases through their immune-suppressive functions. Numerous recent studies have centered on glycolysis of MDSC, investigating the regulation of altered glycolytic pathways to manage diseases. However, the specific changes in MDSC glycolysis and their exact functions continue to be areas of ongoing discussion yet. In this paper, we review a range of current findings, including the latest research on the alteration of glycolysis in MDSCs, the consequential functional alterations in these cells, and the outcomes of attempts to modulate MDSC functions by regulating glycolysis. Ultimately, we will provide insights into whether these research efforts could be translated into clinical applications.
7.Effectiveness of Health Promotion Program Using Action Planning Strategy for Young Adults
Su Hyun KIM ; Min Ji KIM ; Sang Hee KIM ; So Yeon KIM ; Chae Yeon PARK ; Jee Yun BANG
Journal of Korean Academy of Nursing 2019;49(4):461-471
PURPOSE: The purpose of this study was to evaluate the effectiveness of a health promotion program utilizing action planning strategy for young adults. METHODS: A non-equivalent control group pre-post-test design was used. One hundred three university students participated in the study. Participants in the experimental group (n=51) were provided the health promotion program utilizing action planning strategy for five weeks. The program consisted of weekly sessions that included action planning and group feedback. The control group (n=52) was provided with health information every week for 5 weeks. Program outcomes, including self-efficacy, physical activity health behaviors, total exercise time per week, daily cigarette consumption, frequency of alcohol drinking per month, nutritional health behaviors, and subjective health status, were assessed at baseline and at follow-up after 5 weeks. RESULTS: The participants in the experimental group demonstrated significant increases in self-efficacy, physical activity health behaviors, weekly exercise time, and nutritional health behaviors and significant decreases in daily cigarette consumption than those in the control group. CONCLUSION: The health promotion program utilizing action planning strategy is a brief and effective intervention to promote health behaviors among young adults. Further investigation is warranted to assess the program's effectiveness among other age groups and populations at high risk for chronic illness.
Alcohol Drinking
;
Chronic Disease
;
Diagnostic Self Evaluation
;
Follow-Up Studies
;
Health Behavior
;
Health Promotion
;
Humans
;
Motor Activity
;
Self Efficacy
;
Tobacco Products
;
Young Adult
8.Effectiveness of Health Promotion Program Using Action Planning Strategy for Young Adults
Su Hyun KIM ; Min Ji KIM ; Sang Hee KIM ; So Yeon KIM ; Chae Yeon PARK ; Jee Yun BANG
Journal of Korean Academy of Nursing 2019;49(4):461-471
PURPOSE:
The purpose of this study was to evaluate the effectiveness of a health promotion program utilizing action planning strategy for young adults.
METHODS:
A non-equivalent control group pre-post-test design was used. One hundred three university students participated in the study. Participants in the experimental group (n=51) were provided the health promotion program utilizing action planning strategy for five weeks. The program consisted of weekly sessions that included action planning and group feedback. The control group (n=52) was provided with health information every week for 5 weeks. Program outcomes, including self-efficacy, physical activity health behaviors, total exercise time per week, daily cigarette consumption, frequency of alcohol drinking per month, nutritional health behaviors, and subjective health status, were assessed at baseline and at follow-up after 5 weeks.
RESULTS:
The participants in the experimental group demonstrated significant increases in self-efficacy, physical activity health behaviors, weekly exercise time, and nutritional health behaviors and significant decreases in daily cigarette consumption than those in the control group.
CONCLUSION
The health promotion program utilizing action planning strategy is a brief and effective intervention to promote health behaviors among young adults. Further investigation is warranted to assess the program's effectiveness among other age groups and populations at high risk for chronic illness.
9.Relationship between Serum Ghrelin and Insulin Resistance in Obese Children and Adolescents.
Soo Young KIM ; Jung Yeon SHIN ; Min Jee JUNG ; Byung Min CHOI ; Jung Hwa LEE ; Kee Hyoung LEE
Journal of Korean Society of Pediatric Endocrinology 2005;10(2):211-217
PURPOSE: Ghrelin, a 28-amino-acid peptide predominantly produced by the stomach, is endogenous ligand of growth hormone secretagogue receptor and potent stimulator of growth hormone. Ghrelin is also proposed to be orexigenic peptide that induce weight gain by increasing food intake. In general, ghrelin level increase preprandially and decrease after meals and ghrelin is reduced in obese, insulin resistance adults. There is a few available data of ghrelin level in obese children. The aim of this study was to determine whether there was difference of serum ghrelin level between obese and lean children and to evaluate the relationship between ghrelin and insulin resistance. METHODS: The study population consisted of 104 Children (65 males and 39 females) aged 8.0 to 15.0 years. We measured serum glucose and lipid profiles after 8 hr of fasting. Serum insulin and ghrelin were measured by radioimmunoassay. We compared serum ghrelin level between 52 obese children whose body mass index (BMI) greater than the 95th percentile for age and sex and 31 lean children and evaluated the relationship of ghrelin with BMI, fasting glucose, lipid profile and insulin resistance. We also compared serum ghrelin level of fasting and two-hour postprandial state by oral glucose tolerance test in 23 obese children. RESULTS: Mean serum ghrelin concentrations were 445.4 pg/mL in obese children, 504.9 pg/mL in lean children, but not different significantly. The decrease in serum ghrelin with advancing pubertal stage was significantly marked between prepuberty and overt puberty group (P<0.05). The fasting serum ghrelin concentration were negatively associated with height (r=-0.25, P<0.05), weight (r=-0.28, P<0.01), BMI (r=-0.21, P<0.05), fasting insulin concentration (r=-0.27, P<0.01) and HOMA-IR (r=-0.24, P<0.05). After two-hour postprandial state in obese children group, serum ghrelin level were decreased than fasting state (P<0.01). CONCLUSION: Serum ghrelin had no significant difference between obese and lean children but negatively correlated with body mass index and ghrelin were associated with fasting insulin concentration and HOMA-IR. This findings suggest that ghrelin is regulated by feeding state and also modulated by insulin secretion.
Adolescent*
;
Adult
;
Blood Glucose
;
Body Mass Index
;
Child*
;
Eating
;
Fasting
;
Ghrelin*
;
Glucose
;
Glucose Tolerance Test
;
Growth Hormone
;
Humans
;
Insulin Resistance*
;
Insulin*
;
Male
;
Meals
;
Obesity
;
Puberty
;
Radioimmunoassay
;
Receptors, Ghrelin
;
Stomach
;
Weight Gain
10.Ultrasonographic Findings of Fetal Congenital Intracranial Teratoma.
Hak Jong LEE ; Young Ho LEE ; Mi Jin SONG ; Jeong Yeon CHO ; Jee Yeon MIN ; Min Hwan MOON ; Jeong Ah KIM
Journal of the Korean Society of Medical Ultrasound 2005;24(2):55-60
PURPOSE: To evaluate the sonographic findings of fetal congenital intracranial teratoma. MATERIALS AND METHODS: From 1994 to 2002, of the 11 fetuses which had been diagnosed with fetal intracranial tumors after second level fetal ultrasonography, the six that were confirmed after autopsy as congenital intracranial teratomas were included in our study. The sonographic findings, including size, homogeneity, echogenicity compared with surrounding normal brain tissues, cystic components, and tumor related calcification, were retrospectively evaluated. RESULTS: The incidence of fetal congenital intracranial teratoma out of all fetal intracranial tumors was 54.5% (6 of 11 cases) during the 8-year period. The mean mass size was 7.4 cm (3.0-15.0 cm). Two thirds of (4/6) of the teratoma cases showed high echogenicity compared with normal brain tissues, and two thirds (4/6) showed heterogeneous echogenicity. Four teratoma cases (67%) showed cysts in the mass with a mean size of 1.9cm. One third (2/6) showed calcifications within the tumor. Out of the six cases, two had oropharyngeal teratoma with extension into the intracranial portion (so called epignathus) and showed homogenous mass without any cysts or calcifications. CONCLUSION: The typical sonographic appearance of intracranial teratoma was a heterogeneous, hyperechoic mass with cysts. In the epignathus cases, the sonographic appearances differed somewhat from the others. An understanding of the sonographic findings of fetal intracranial teratoma will help in the timely counseling of the parents and in obstetric decision making.
Autopsy
;
Brain
;
Counseling
;
Decision Making
;
Fetus
;
Humans
;
Incidence
;
Parents
;
Retrospective Studies
;
Teratoma*
;
Ultrasonography
;
Ultrasonography, Prenatal