1.Study on the Effects of Epidermal Growth Factor on Epidermal and Hair Growth in the Mouse.
Korean Journal of Dermatology 1985;23(6):726-735
Epiclerrnal growth factor(EGF), a low-molecular-weight polypeptide chain consisting of 53 amino acids, stimulates the growth and keratinization of epidermal cells. Recently, some authors reported that hair growth rate and follicular bulb growth were inhibited by EGF in neonatal mice. Since the hair and follicular cells are of epidermal origin, the effect of EGF would appear to be inconsistent with its role promoting the proliferation and differentiation of epidermal cells in vivo and in vitro. We have investigated the effects of EGF on the hair and epidermis in adult male mouse. The results are summarized as follows: l. 1'he hair length and maximum diameter were significantly reduced in EGF- treated regions compared with control group, and inhibition of hair growth was correlated with EGF dose. Thickness of the epidermis was significantly increased in EGF-treated regions compared with control group, and proliferation of the epidermis was correlated with EGF dose. 3 There were no significant differences in the hair length, maximum diameter, and egidermal thickness between untreated contralateral right mid-side regions of EGF-treated groups and control group.
Adult
;
Amino Acids
;
Animals
;
Epidermal Growth Factor*
;
Epidermis
;
Hair*
;
Humans
;
Male
;
Mice*
2.A Case of Malignant Pyoderma.
Jee Ho CHOI ; Jai Il YOUN ; Yoo Shin LEE
Korean Journal of Dermatology 1984;22(4):413-417
Malignant pyoperma is a rare, chronic, progressive, destructive ulcerating skin disease of unknown cause that affects the head and neck region of young adults. The disease is progressive but responds to high doses of systemically administered steroids. We present a case of malignant pyoderma developed on the left retroauricular area in 67 year-old male. The patient died of rapidly progressive, desructive, 15cm x 20 cm sized, phagedenic ulcer on the left retroauricular and neck area despite of various extensive local and systemic treatment. Histopathologic findings of tissue from the edge of the ulcer were non-specific, showing upper dermal necrosis and mixed inflammatory cell infiltrate in the deep dermis.
Aged
;
Dermis
;
Head
;
Humans
;
Male
;
Neck
;
Necrosis
;
Pyoderma*
;
Skin Diseases
;
Steroids
;
Ulcer
;
Young Adult
3.Two Cases of Contact Dermatitis due to Tiger Balm(R).
Hee Chul EUN ; Jee Ho CHOI ; Yoo Shin LEE
Korean Journal of Dermatology 1984;22(5):517-521
No abstract available.
Dermatitis, Contact*
;
Tigers*
4.A Case of Solitary Fibrofolliculoma.
Kyu Han KIM ; Jee Ho CHOI ; Yoo Shin LEE
Korean Journal of Dermatology 1984;22(6):672-674
The fibrofolliculoma is characterized by abnormal hair follicles with epithelial strands extending out from the infundibulum of the hair follicle into a hyperplastic mantle of specialized fibrous tissue. We have seen a peculiar case of a 1 year and 2 months old male who had a solitary papule on the left side of his face which histologically showed a typical fibrofolliculoma pattern.
Hair Follicle
;
Humans
;
Infant
;
Male
5.The significance of the morphology of ventricular premature complex(VPC) as a marker for left ventricular structure and function.
Jee Ae SHIN ; Dong Il LEE ; Kook Jin CHUN ; Chang Hyung MOON ; Yung Woo SHIN ; Yeong Kee SHIN
Korean Circulation Journal 1993;23(2):273-280
BACKGROUND: There has been reports which suggest that the morphologic feature of ventricular premature complex(VPC) might reflect the cardiac state. METHODS: To test this, we studied retrospectively the association between the morphologic feature of VPC(shape and duration) and cardiac state(structural and functional) by analysing the records of ECG(179 cases) obtained from reviewing echocardiogram performed in our hospital from 1988 to early 1991. Group 1(n=84) had VPC-QRS complexes with either smooth and uniterruped contour or narrow(<0.04 sec) notching and group 2(n=95) demonstrated VPC with broad(> or =0.04 sec) notching or shelves. Without taking into account of either the presence of the type of the underlying cardiac disease and other constitutional disease state, we classified the type of VPC on ECG according to the above criteria and analysed its simple association with cardiac size and functional state on echocardiogram. RESULTS: In group 1, 68 of 84 cases with a VPC had no notching. In group 2, the VPC-QRS duration was greater than group 1(0.154+/-0.022 vs 0.141+/-0.011 sec(mean+/-S.D.), p=0.0001).Left ventricular end-diastolic diameter(LVED) and ejection fraction(EF) showed a significant difference between the two groups(5.12+/-0.64 vs 5.72+/-0.95cm, p=0.0003 and 65.89+/-10.84 vs 60.82+/-15.5%, p=0.012 respectively). In group 2, 50 of 95 cases(53%) showed ejection fraction less than 64%. By defining left ventricular structural dilatation and functional impairment on echocardiogram as LEVD greater than 5.5cm and EF less than 64% respectively, the sensitivity and specificity of VPC morphology was 60% and 74% respectively. CONCLUSIONS: We conclude that a broadly(> or =0.04 sec) notched VPC of long duration(> or =0.15 sec) is a simple and reliable 12-lead ECG marker for an abnormal structural and functional state of the heart(dilatation and hypokinetic left ventricle), irrespective to underlying cardiac disease, while a VPC with smooth contour or narrow(<0.04 sec) notching with short duration(<0.15 sec) reflects a normal sized heart with normal systolic function.
Dilatation
;
Electrocardiography
;
Heart
;
Heart Diseases
;
Retrospective Studies
;
Sensitivity and Specificity
6.A Prospective Study of Urinary beta2 -Microglobulin in Infants with Meconium-Stained Amniotic Fluid.
Sung Oh KIM ; Jeh Hoon SHIN ; Woo Gill LEE ; Soo Jee MOON ; Keun Soo LEE
Journal of the Korean Pediatric Society 1988;31(8):968-976
No abstract available.
Amniotic Fluid*
;
Female
;
Humans
;
Infant*
;
Prospective Studies*
7.A Case of Sebaceous Carcinoma.
Joon Mo YANG ; Jeung Hoon LEE ; Jee Ho CHOI ; Yoo Shin LEE
Korean Journal of Dermatology 1982;20(6):951-955
Sebaceous carcinoma of the eyelids is rare and is usually seen in the elderly persons. The meibomian glands of the tarsus are the frequent sites of origin. The characteristic feature is a firm, painless nodule on the upper eyelid, We present a typical case of the sebaceous carcinoma in 60 year-old female. The patient had 1 * 1cm sized, hard, fixed, non-tender mass with bleeding on the right lateral canthus of 3~4 months duration. The histopathology of the lesion showed irregular sized lobules in the dermis with invasive growth to the surrounding stroma. Many fat containing sebaceous celles are seen in the center of the lobules.
Aged
;
Ankle
;
Dermis
;
Eyelids
;
Female
;
Hemorrhage
;
Humans
;
Meibomian Glands
;
Middle Aged
8.Percutaneous Vertebroplasty in Spinal Metastasis and Myeloma:25 Cases Experience.
Woo Min PARK ; Jee Soo JANG ; Chang Hun RHEE ; Ho Shin GWAK ; Seung Hoon LEE
Journal of Korean Neurosurgical Society 2000;29(11):1484-1490
No abstract available.
Neoplasm Metastasis*
;
Vertebroplasty*
9.Clinical Observation of Viral Hepatitis.
Han Ku MOON ; Chang Moo LEE ; Myung Hi SHIN ; Jee Sub OH
Journal of the Korean Pediatric Society 1982;25(11):1097-1105
No abstract available.
Hepatitis*
10.Epidural Granulocytic Sarcoma Causing Cord Compression at Thoracic Region in Acute Myelogenous Leukemia: A Case Report.
Woo Min PARK ; Jee Soo JANG ; Chang Hun RHEE ; Ho Shin GWAK ; Seung Hoon LEE
Journal of Korean Neurosurgical Society 2000;29(11):1533-1537
No abstract available.
Leukemia, Myeloid, Acute*
;
Sarcoma, Myeloid*