As the incidence of dermographism in our urticaria clinie is quite high comparing data in other country, we have tried to survey the incidence of ermographism in the general population of Korea using a dermographic tester designed by other author. Total 8g7 healthy persons were included in this study from March J98$ to .December 1983. The study result was summarized as follows, 1. Male to female ratio was 2. 5: 1 and the peak age of the subjects was third(47 8%), fourth and fith decades in ecreasing order, The overall incidence of dermographisrn from the pressure of 48ppg/cm was 4.4% and there were no significa.nt difference in the incidences between male(4, 2%) and female(4 7%) (p>0. 1), and between the different age groups(p>0 l)
Female ; Humans ; Incidence* ; Korea ; Male ; Urticaria

Background and Objectives: There is growing evidence supporting the association between ultra-processed food (UPF) consumption and metabolic disease risk. However, little is known about the association between UPF consumption and blood pressure (BP). Thus, this study examined the association between UPF consumption and elevated BP in Korean adults. Methods: This study used data from the Korea National Health and Nutrition Examination Survey (2016–2018) and included 9,188 participants aged 30–79 years without a history of hypertension diagnosis. Food items reported in a one-day 24-hour recall were categorized on the basis of the NOVA (not an acronym) food classification criteria. UPF consumption was estimated as the contribution to total energy intake. Elevated BP was defined as systolic BP ≥120 mmHg or diastolic BP ≥80 mmHg. The independent association between UPF consumption and elevated BP was assessed by multivariable logistic regression analysis. Results: The upper tertile of UPF consumption was significantly associated with elevated BP compared with the lower tertile, after adjusting for potential confounders. A linear trend was observed for elevated BP across the tertiles of the dietary energy contribution of UPF. Similar results were found in stratified analyses by age group, smoking, obesity, and overall dietary quality. However, a marginal level of association was found in some subgroups, current smokers, and non-obese adults. Conclusions The dietary energy contribution of UPF consumption was positively associated with increased prevalence of elevated BP, and these findings suggest that lowering UPF consumption might help prevent BP elevation.

Guillain-Barré syndrome (GBS) is nowadays consider as an umbrella term that has heterogenous presentation depend on their subtypes. GBS is clinical diagnosis and its diagnosis can be supported by laboratory findings from cerebral spinal fluid study, nerve conduction study, anti-ganglioside antibodies, spinal magnetic resonance imaging and nerve ultrasound. Understanding atypical subtypes and GBS mimicking diseases are crucial for correct diagnosis. Both proper medical care for respiratory and autonomic dysfunction and immunotherapy are essential to improve outcome of GBS. Here, we summarized the current concept on diagnosis, immunopathophysiology and treatment of GBS.
Antibodies ; Diagnosis ; Guillain-Barre Syndrome ; Immunotherapy ; Magnetic Resonance Imaging ; Neural Conduction ; Ultrasonography

PURPOSE: We assessed changes of the choroidal thickness in healthy Korean children using enhanced depth imaging (EDI) optical coherence tomography (OCT) and evaluated the association of choroidal thickness and axial length. METHODS: Seventy-nine eyes (79 children) within +/-1 diopter spherical equivalent underwent horizontal and vertical scan using EDI OCT. Two observers determined independently the choroidal thickness at 1 mm intervals from 3 mm nasal and 4 mm temporal to the fovea and 1 mm superior and inferior to the fovea using the manual caliper provided by the device software. Statistical analysis was performed to evaluate variations of choroidal thickness at each location and to correlate choroidal thickness and axial length. Intraclass correlation coefficient (ICC) was calculated. RESULTS: The subjects' mean age was 7.67 years. The mean axial length was 22.96 mm and mean subfoveal choroidal thickness was 296.13 microm. The thinnest choroidal thickness was 160.57 microm at 3 mm nasal to the fovea and the thickest was 319.49 microm at 4 mm temporal to the fovea. The choroidal thickness at 1 mm superior (294.70 microm) and inferior (287.11 microm) to the fovea showed no statistical significance compared with the subfoveal choroidal thickness. The mean choroidal thickness was thicker at 3 mm and 2 mm nasal to the fovea in eyes with shorter than the mean axial length (p < 0.05). For the assessment of intra-observer reproducibility, the ICC ranged from 0.995 to 0.998 (p < 0.001). CONCLUSIONS: The choroidal thickness increased from the nasal to the temporal direction at the posterior pole and eyes with shorter axial lengths tended to present thicker choroids at the nasal area in healthy Korean children.
Child* ; Choroid* ; Humans ; Tomography, Optical Coherence*

Tuberous sclerosis is a rare hereditary anomaly of variable penetrance characterized by mental retardation, epilepsy, and adenoma sebaceum. Pulmonary involvement is uncommon, but, when involve by tuberous sclerosis, it shows characteristic reticulonodular infiltration and cystic changes. Lymphangioleiomyomatosis is a rare disease of unknown cause that affects women of reproductive age. It is characterized by progressive proliferation of smooth muscle in the lung. We experienced one case of pulmonary lymphangioleiomyomatosis associated with tuberous sclerosis in a 26-year-old female patient. This case is reported with a brief of the literature.
Adult ; Angiomyolipoma* ; Epilepsy ; Female ; Humans ; Intellectual Disability ; Lung ; Lymphangioleiomyomatosis* ; Muscle, Smooth ; Penetrance ; Rare Diseases ; Tuberous Sclerosis*

No abstract available.
Motor Neurons* ; Urinary Bladder, Neurogenic* ; Urodynamics*

The Dieulafoy's lesion is a rare cause of recurrent massive gastrointestinal bleeding in children. The bleeding results from an abnormally large submucosal artery that protrudes through a small mucosal defect. The lesion is commonly found on proximal stomach. Surgical intervention was believed to be the best treatment in the past, but recent advancement in endoscopy has made effective hemostasis possible. We report a case of a 9-year-old boy with underlying mycoplasma pneumonia with effusion who presented with massive upper gastrointestinal bleeding. Bleeding was controlled with endoscopic treatment by epinephrine and ethanol injection and the patient was successfully treated.
Arteries ; Child* ; Endoscopy ; Epinephrine ; Ethanol* ; Hemorrhage ; Hemostasis ; Humans ; Male ; Pneumonia, Mycoplasma ; Stomach

BACKGROUND: To investigate the relationship between adiposity and risk factors for cardiovascular disease (CVD) in normal weight individuals. METHODS: The study subjects were those over 19 years old, less than 23 kg/m2 of body mass index (BMI). They were examined in a health promotion center of a general hospital from June to November, 2001 (309 men and 369 women). Height, weight, BMI, blood pressure (BP), serum lipids and fasting blood glucose (FBS) were checked. Percent body percent (%BF) was obtained by bioelectrical method. Normal weight subjects were divided into two groups according to their %BF; then, the groups were evaluated for the presence of CVD risk factors. RESULTS: The average age of the study subjects was 43.66+/-11.26 years old in men and 41.11+/-10.90 years old in women. The average BMI was 21.15+/-1.47 kg/m2 in men and 20.68+/-1.53 kg/m2 in women. High %BF group showed significantly increased frequency of higher BP, FBS, total cholesterol (TC), triglyceride (TG) and LDL-cholesterol (LDL-C) compared with low %BF group in both sexes. In men, odds ratios (ORs) of the high %BF group with respect to the low %BF group were significantly high for BP and TG elevation. ORs of the high %BF group were significantly high for FBS, TC, LDL-C and TG elevation in women. ORs for more than one CVD risk factor was 2.46 (1.38~4.38) in men and 1.50 (0.95~2.36) in women. CONCLUSION: Increased %BF was related to cardiovascular risk factors in normal weight subjects. The result was more significant for normal weight men than normal weight women.
Adipose Tissue* ; Adiposity ; Adult* ; Blood Glucose ; Blood Pressure ; Body Mass Index ; Cardiovascular Diseases ; Cholesterol ; Fasting ; Female ; Health Promotion ; Hospitals, General ; Humans ; Male ; Odds Ratio ; Risk Factors* ; Triglycerides

The most characteristic radiological finding following methanol intoxication is bilateral necrosis of the putamina with varying degrees of hemorrhage. We report here on a 61-year-old Russian male with methanol intoxication who had delayed cerebral hemorrhage with a fatal course. The magnetic resonance image taken on admission revealed diffusion restriction lesions in the bilateral putamina, thalamus, and frontal and occipital subcortical white matter, without hemorrhage. Brain computed tomography performed on the 18th day revealed extensive bilateral hemorrhage in the multiple subcortical white matter, which led ultimately to death.
Brain ; Cerebral Hemorrhage ; Diffusion ; Hemorrhage ; Humans ; Magnetic Resonance Spectroscopy ; Male ; Methanol ; Middle Aged ; Necrosis ; Thalamus

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis that commonly affects the peripheral nervous system. EGPA rarely presents with acute polyneuropathy resembling Guillain-Barré syndrome (GBS). A 51-year-old female patient with a history of asthma suddenly developed bilateral lower extremityparesthesia that progressed to asymmetric ascending paralysis within 10 days of onset. Nerve conduction study results were compatible with acute motor sensory axonal neuropathy, consistent with a GBS subtype. A clinical and neurophysiological diagnosis of GBS was made, and high-dose intravenous immunoglobulins were administered. However, the patient's painful motor weakness persisted. Furthermore, she had newly developed skin lesions on her back, face, and arms. Her blood test revealed marked eosinophilia (>60%). In addition, antineutrophil cytoplasmic antibodies were reported positive. A Water's view radiographic image showed bilateral maxillary sinusitis. Considering the history of asthma, we suspected EGPA-associated polyneuropathy and started steroid treatment. The patient's strength and eosinophilia improved rapidly and dramatically. EGPA can mimic GBS and should be differentiated because of different treatment strategies. Early diagnosis and prompt treatment help achieve a good outcome.
Antibodies, Antineutrophil Cytoplasmic ; Arm ; Asthma ; Axons ; Diagnosis ; Early Diagnosis ; Eosinophilia ; Eosinophils ; Female ; Granulomatosis with Polyangiitis ; Guillain-Barre Syndrome ; Hematologic Tests ; Humans ; Immunoglobulins, Intravenous ; Maxillary Sinus ; Maxillary Sinusitis ; Middle Aged ; Neural Conduction ; Paralysis ; Peripheral Nervous System ; Polyneuropathies ; Skin ; Systemic Vasculitis