Winkelmann granuloma is a very rare disorder characterized by histologic findings of perhaps[ic] infiltration, collagen degeneration, and granulomatous inflammation, which usually show palisading features. A number of diseases, especially systemic immunoreactive diseases, are associated with this disorder. We describe a focal neutrophilic necrosis : type of Winkelmann granuloma associated with hypothy- roidism and rheumatoid arthritis.
Arthritis, Rheumatoid* ; Collagen ; Granuloma* ; Hypothyroidism* ; Inflammation ; Necrosis ; Neutrophils

Lichenoid keratosis (LK), a lichen planus-like keratosis, is a rather frequent skin disorder that has some histological features similar to lichen planus. However, the classification system for LK has not been settled. We report two cases of LK and propose a new classification for LK correlating with clinicohistopathological findings.
Actins* ; Classification ; Keratosis* ; Lichen Planus ; Lichens ; Skin

Indeterminate cell proliferations are rarely described in dermatology literature. Indeterminate cells are characterized by positivity for S-100 protein and CD-la, but are distinguished from Langerhans cells by the absence of Birbeck granules. We present a case of congenital indeterminate cell histiocytoma in a 6-day-old male infant. A Skin examination revealed a solitary, erythematous, 6*6cm, superficially crusted, dome shaped papule on his forehead. A Histopathologic examination showed a dense cellular infiltrate in the dermis, below the atrophic epidermis. Frequently, the nucleus demonstrated a single cleft or crease like the shape of a kidney. These cells showed positivity for S-100 protein. Birbeck granules were not found on electron microscopic examination.
Dermatology ; Dermis ; Epidermis ; Forehead ; Histiocytoma* ; Humans ; Infant ; Kidney ; Langerhans Cells ; Male ; S100 Proteins ; Skin

Cutaneous metastasis from parotid gland carcinoma is very rare and there have been no re-ports in Korean literatures. Furthermore, it can often manifest as inflammatory type of skin metastasis and mimic a radiodermatitis. We report a case of a 31-year-old Korean man with cutaneous metastasis originated from parotid gland mucoepidermoid carcoinoma which mimicked clinically a radiodermatitis.
Adult ; Carcinoma, Mucoepidermoid* ; Humans ; Neoplasm Metastasis* ; Parotid Gland* ; Radiodermatitis* ; Skin*

Cutaneous pseudolymphoma (CPL) has a microscopic appearance that resembles that of cutaneous lymphoma, but shows a clinically benign course. The differential diagnosis of CPL with cutaneous lymphoma is very important because clinical outcomes of them are quite different. We herein describe two cases of B-cell pseudolymphoma, which were difficult to differentiate from cutaneous B-cell lymphlma. All of two cases, Polymerase chain reaction of immunoglobulin heavy chain gene rearrangement showed polyclonal pattern.
B-Lymphocytes* ; Diagnosis, Differential ; Gene Rearrangement ; Immunoglobulin Heavy Chains ; Lymphoma ; Polymerase Chain Reaction ; Pseudolymphoma*

Wiscott-Aldrich syndrome (WAS) is an X-linked recessive disorder affecting males and is characterized by recurrent systemic bacterial and viral infections, purpura due to thrombocytopenia, and an atopic dermatitis-like skin eruption. WAS usually manifests itself early during the first few weeks or months of life with bleeding. A case of WAS with the classical symptoms(eczema, thrombocytopenia and susceptibility to infections) is described in a 12-year-old Korean boy. He had a relatively good outcome.
Child ; Hemorrhage ; Humans ; Male ; Purpura ; Skin ; Thrombocytopenia

Epithelioid sarcoma is a rare distinctive malignant neoplasm of soft tissue with frequent recurrences and late metastases. It typically affects young adult males, and epithelioid sarcoma arising in the first decade of life is very rare. Epithelioid sarcoma may be confused with a wide range of benign, especially granulomatous, diseases and other malignancies, but the differentiation can be made, in general, by the characteristic clinical, histopathologic, and immunohistochemical features. We report herein a case of epithelioid sarcoma arising on the volar side of the right 5th finger in an 8-year-old boy. To our knowledge, this is the first report of epithelioid sarcoma in a Korean child.
Child* ; Fingers ; Humans ; Male ; Neoplasm Metastasis ; Recurrence ; Sarcoma* ; Young Adult

No Abstract Available.
Leukemia* ; Leukemic Infiltration* ; Skin*

A 57-year-old Korean man with malignant fibrous histiocytoma (MFH) on the leg is presented. Histopathologic examination was consistent with a pleomorphic -storiform subtype of MFH with highly pleomorphic cellular features and frequent mitosis. According to recent evidences, MFH might be a heterogenous group of poorly differentiated tumors rather than a distinct entity. Our case was only positive to CD68 and vimentin immunohistochemically.
Histiocytoma, Malignant Fibrous* ; Humans ; Leg ; Middle Aged ; Mitosis ; Vimentin

No abstract available.
Steatocystoma Multiplex*