1.A Case of Tuberculous Meningoencephalitis Presenting as Prominent Psychotic Features.
Hyun Jung YU ; Jee Young OH ; Jee Hyun KIM ; Jung Eun KIM ; Kee Duk PARK
Tuberculosis and Respiratory Diseases 2001;51(6):603-608
Intracranial vasculitis is a rare and disastrous complication of tuberculous meningitis if not treated properly. Focal neurologic deficits according to the vessels involved are common manifestation. Here, we report a 29-year-old man who suffered abrupt, bizarre behavioral changes caused by vasculitis complicating tuberculous meningoencephalitis. The diagnosis of tuberculous meningitis is based upon both the CSF findings and a chest X-ray. His systemic symptoms disappeared by after being administered antituberculous medication but various psychotic features such as hypersomnia, hyperphagia and aggressivebehavior continued. A brain MRI showed multiple small parenchymal tuberculous nodules, and the brain MR angiography revealed a narrowing of the proimal middle cerebral arteries and a reduced visualization of the cerebral vessels, suggesting widespread vasculitis. Intravenous dexamethasone successfully ameliorated his behavioral changes. In addition both the follow up brain MRI and angiography showed a normalization of the previous findings.
Adult
;
Angiography
;
Brain
;
Dexamethasone
;
Diagnosis
;
Disorders of Excessive Somnolence
;
Follow-Up Studies
;
Humans
;
Hyperphagia
;
Magnetic Resonance Imaging
;
Meningoencephalitis*
;
Middle Cerebral Artery
;
Neurologic Manifestations
;
Thorax
;
Tuberculosis
;
Tuberculosis, Meningeal
;
Vasculitis
2.A Case of Steroid-induced Atrophy of External Genitalia.
Jee Hyun JEON ; Jee Min PARK ; Eun Gyong YOO ; Duk Hee KIM
Journal of Korean Society of Pediatric Endocrinology 2001;6(2):160-164
Skin atrophy is one of the most common side effects of topical steroid use and results from decreased skin proalphaI collagen mRNA production due to specific alterations in collagen gene transcription or from reduced collagen mRNA stability. This report describes a case of a 8 year-old-girl who visited our hospital with a complaint of ambiguous genitalia. She was observed to have atrophic labia majora and atrophic striae resembling scrotal rugae. However, her serum levels of FSH, LH, 17-KS, 17-OHCS, 5-DHT, DHT and DHEA-S were all in normal range and her karyotype was 46,XX. Abdominal and pelvic ultrasonogram showed a normal uterus and ovaries. Careful history taking revealed frequent use of steroid ointment due to vulvar pruritus for 2 years and she was finally diagnosed to have atrophy of external genitalia induced by long-term use of topical steroid.
Atrophy*
;
Collagen
;
Disorders of Sex Development
;
Female
;
Genitalia*
;
Karyotype
;
Ovary
;
Pruritus
;
Reference Values
;
RNA Stability
;
RNA, Messenger
;
Skin
;
Ultrasonography
;
Uterus
3.Periorbital Lipogranuloma after Autologous Fat Injection for Facial Augmentation.
Hyun Jee KIM ; Jun Young LEE ; Ji Hyun LEE ; Young Min PARK
Korean Journal of Dermatology 2017;55(3):222-223
No abstract available.
4.Erratum: In vitro growth of mouse preantral follicles: effect of animal age and stem cell factor/insulin-like growth factor supplementation.
Byung Chul JEE ; Jee Hyun KIM ; Da Hyun PARK ; Hyewon YOUM ; Chang Suk SUH ; Seok Hyun KIM
Clinical and Experimental Reproductive Medicine 2012;39(4):193-193
This article was published with an incorrect unit in Table 1.
5.The Relationship of VO2Max/Min in cardiopulmonary exercise test and fat distribution.
Jae Chol CHOI ; Hyun Suk JEE ; Young Bum PARK ; Sung Jin PARK ; Jee Hoon YOO ; Jae Yeol KIM ; In Won PARK ; Byoung Whui CHOI ; Sung Ho HUE
Tuberculosis and Respiratory Diseases 2000;49(4):495-501
BACKGROUND: Cardiopulmonary exercise test is a useful test for the evaluation of the cardiovascular and respiratory systems. Obese subjects have an increased resting metabolic rate (VO2) compared to non-obese subjects and the increase is more marked during dynamic exercise, which results in the limitation of maximal exercise in obese subjects. In this study, the influence of the obesity and fat distribution on the maximal exercise capacity were evaluated. METHODS: Maximal exercise capacity was represented by maximam maximum oxygen uptake and VO2 max in the cardiopulmonary test. Obesity, total fat content and abdominal obesity(waist to hip ratio, WHR) were measured by bioelectrical impedence method. Total of 42 volunteers(male 22, female 20) were evaluated. RESULTS: 1) Weight to height ratio(mean±SD) was 110%±14.9% in men and 100±11.1% in women. 2) Fat ratio(mean±SD) was 23.3±5.2% in men and 27.55±3.9% in woman. 3) Waist to hip ratio(mean±SD) was 0.85±0.04 in men and 0.8±0.03 in woman. 4) In men, VO2max/min/Kg was negatively correlate with obesity, fat ratio, and abdominal fat distribution. 5) In woman, VO2max/Kg was negatively correlated with obesity and fat ratio, but did not show significant relationship with abdominal fat distribution. CONCLUSION: Obesity was a limiting factor for maximal exercise in both men and women. Abdominal obesity was a limiting factor for maximal exercise in men but its implication to women needs further evaluation.
Abdominal Fat
;
Exercise Test*
;
Female
;
Hip
;
Humans
;
Male
;
Obesity
;
Obesity, Abdominal
;
Oxygen
;
Respiratory System
6.An Ulcerative Amelanotic Melanoma on the Heel.
So Young YOON ; Young Woon PARK ; Eun Jee KIM ; Hyun Sun PARK ; Hyun Sun YOON ; Soyun CHO
Korean Journal of Dermatology 2013;51(12):995-996
No abstract available.
Heel*
;
Melanoma, Amelanotic*
;
Ulcer*
7.A Case of Primary Lateral Sclerosis Showing Degeneration ofCorticospinal Tract on Magnetic Resonance Imaging.
Jee Young OH ; Hyun Jung YU ; Jee Hyun KIM ; Jung Eun KIM ; Kyoung Gyu CHOI ; Kee Duk PARK
Journal of the Korean Neurological Association 2000;18(6):801-804
Primary lateral sclerosis (PLS) is a rare upper motor neuron disease characterized by selective degeneration of corticospinal and corticobulbar tracts. It is important to rule out other diseases presenting as progressive spastic paraparesis, such as multiple sclerosis (MS) or amyotrophic lateral sclerosis (ALS). Though that is not so difficult as the development of imaging technique and neurophysiological tool, if one shows slow progressive spastic paraparesis clinically, and there is no abnormal CSF or EMG findings, it is not easy to differentiate between primary progressive MS and PLS. In fact, PLS is so rare that it has long been debated whether PLS is a disease entity or syndrome or a nothing. But we present a PLS patient whose brain MRI shows diffuse signal change along the bilateral corticospinal tracts and the hypoperfusion of frontal motor cortex is proved by brain SPECT.
Amyotrophic Lateral Sclerosis
;
Brain
;
Humans
;
Magnetic Resonance Imaging*
;
Motor Cortex
;
Motor Neuron Disease*
;
Multiple Sclerosis
;
Paraparesis, Spastic
;
Pyramidal Tracts
;
Tomography, Emission-Computed, Single-Photon
8.The Correlation between Severity of Sleep Apnea, Sleep and Mood Related Scales, and Activity During Sleep in Obstructive Sleep Apnea Syndrome Patients.
Kyu Hee HAN ; Minah SOH ; Jee Hyun HA ; Seung Ho RYU ; Jaehak YU ; Doo Heum PARK
Sleep Medicine and Psychophysiology 2011;18(2):76-81
OBJECTIVES: This study aims to analyze the association between the severity of sleep apnea, sleep and mood related scales, and activity during sleep in obstructive sleep apnea syndrome (OSAS) patients. METHODS: One hundred seventy six drug-free male patients confirmed as OSAS (average age=43+/-11 years) were selected through nocturnal polysomnography (NPSG). OSAS was diagnosed with apnea-hypopnea index (AHI) >5, mean AHI was 39.6+/-26.0. Sleep related scales were Stanford Sleepiness Scale (SSS), Epworth Sleepiness Scale (ESS), Pittsburg Sleep Quality Index (PSQI) and Morningness-Eveningness Scale (MES). Mood related scales were Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), State-Trait Anxiety Inventory (STAI) I, II and Profile of Mood States (POMS). NPSG was performed overnight with both wrist actigraphy (WATG). Parameters produced from WATG were total activity score, mean activity score and fragmentation index. We analyzed the correlation between each scale, AHI scored from NPSG and activity score analyzed from WATG. RESULTS: ESS showed significant positive correlation with PSQI, BDI, BAI and STAI I, II, respectively (p<0.01). SSS showed significant positive correlation with PSQI and BAI (p<0.05, p<0.01). BAI showed significant positive correlation with total activity score, mean activity score and fragmentation index (p<0.05, p<0.01, p<0.05). Total activity score showed significant positive correlation with ESS and BAI, respectively (p<0.05). Fragmentation index showed significant positive correlation with ESS, PSQI and BAI (p<0.05, p<0.01, p<0.05). AHI, indicator of sleep apnea is showed no significant correlation with each sleep and mood related scale. CONCLUSION: The degree of daytime sleepiness tends to be associated with night sleep satisfaction, depression and anxiety, and the activity during sleep rather than the severity of sleep apnea.
Actigraphy
;
Anxiety
;
Depression
;
Humans
;
Male
;
Polysomnography
;
Sleep Apnea Syndromes
;
Sleep Apnea, Obstructive
;
Weights and Measures
;
Wrist
9.Massive Spontaneous Suprachoroidal Hemorrhage in a Patient with Heavy Alcohol Consumption.
Journal of the Korean Ophthalmological Society 2015;56(2):296-299
PURPOSE: To report a case of massive spontaneous suprachoroidal hemorrhage in a middle-aged female with heavy alcohol consumption. CASE SUMMARY: A 48-year-old female with a history of heavy alcohol consumption developed a massive spontaneous suprachoroidal hemorrhage in the right eye. Fundus examination and B-scan ultrasonography of the right eye revealed a hemorrhagic choroidal detachment with kissing choroidal sign. On systemic evaluation, she was diagnosed with alcohol-induced hepatitis, diabetes, and diabetic nephropathy. We performed trans-scleral drainage of the suprachoroidal hemorrhage, trans pars plana vitrectomy and silicone oil injection in her right eye. CONCLUSIONS: To our knowledge, this is the first case report of massive spontaneous suprachoroidal hemorrhage in a patient with heavy alcohol intake.
Alcohol Drinking*
;
Choroid
;
Diabetic Nephropathies
;
Drainage
;
Female
;
Hemorrhage*
;
Hepatitis
;
Humans
;
Middle Aged
;
Silicone Oils
;
Ultrasonography
;
Vitrectomy
10.Factors influencing serum progesterone level on triggering day in stimulated in vitro fertilization cycles.
Ju Hee PARK ; Byung Chul JEE ; Seok Hyun KIM
Clinical and Experimental Reproductive Medicine 2015;42(2):67-71
OBJECTIVE: Elevated serum progesterone (P) levels on triggering day have been known to affect the pregnancy rate of in vitro fertilization (IVF). This study aimed to identify the possible factors influencing serum P levels on triggering day in stimulated IVF cycles. METHODS: Three hundred and thirty consecutive fresh IVF cycles were included in the study. All cycles were first attempts and were performed in a single infertility center. The indications for IVF were male factor infertility (n=114), ovulatory infertility (n=84), endometriosis (n=61), tubal infertility (n=59), unexplained infertility (n=41), and uterine factor infertility (n=39). A luteal long protocol of a gonadotropin-releasing hormone (GnRH) agonist (n=184) or a GnRH antagonist protocol (n=146) was used for pituitary suppression. Ovarian sensitivity was defined as the serum estradiol level on triggering day per 500 IU of administered gonadotropins (OS[a]) or the retrieved oocyte number per 500 IU of administered gonadotropins (OS[b]). RESULTS: Univariate analysis revealed that the serum P level on triggering day was associated with the serum estradiol level on triggering day (r=0.379, p<0.001), the number of follicles > or =14 mm (r=0.247, p<0.001), the number of retrieved oocytes (r=0.384, p<0.001), and ovarian sensitivity (OS[a]: r=0.245, p<0.001; OS[b]: r=0.170, p=0.002). The woman's age, body mass index, antral follicle count, and basal serum follicle stimulating hormone and estradiol levels were not associated with serum P level on triggering day. The serum P level on triggering day did not show significant variation depending on the type or cause of infertility, pituitary suppression protocol, or the type of gonadotropins used. CONCLUSION: The serum P level on triggering day was closely related to the response to ovarian stimulation.
Body Mass Index
;
Endometriosis
;
Estradiol
;
Female
;
Fertilization in Vitro*
;
Follicle Stimulating Hormone
;
Gonadotropin-Releasing Hormone
;
Gonadotropins
;
Humans
;
Infertility
;
Male
;
Oocytes
;
Ovulation Induction
;
Pregnancy Rate
;
Progesterone*