Presurgical prosthetic treatment planning is critical for the success of the implant prosthesis. Inadequate treatment plan, due to insufficient discussion between prosthodontist, and surgeon, may result in poor prognosis. A 26-year-old male patient was referred for prosthodontic treatment after implant was placed in the area of teeth #17, 16, 22, 25 and 27, without adequate discussion nor the treatment planning between oral surgeon and prosthodontist. It was found that the patient had two hopeless teeth, and a severely resorbed alveolar ridge. Additional tooth extraction was needed and the type of definitive prosthesis was shifted from fixed type to removable one. Proper pre-surgical treatment planning is essential for the good prognosis. Implant-supported removable prosthesis on milled bars may be a useful treatment option in patients with incorrect angled placement on severely resorbed alveolar ridge.
Adult ; Alveolar Process ; Denture, Partial, Removable ; Humans ; Male ; Prognosis ; Prostheses and Implants ; Prosthodontics ; Tooth ; Tooth Extraction

Presurgical prosthetic treatment planning is critical for the success of the implant prosthesis. Inadequate treatment plan, due to insufficient discussion between prosthodontist, and surgeon, may result in poor prognosis. A 26-year-old male patient was referred for prosthodontic treatment after implant was placed in the area of teeth #17, 16, 22, 25 and 27, without adequate discussion nor the treatment planning between oral surgeon and prosthodontist. It was found that the patient had two hopeless teeth, and a severely resorbed alveolar ridge. Additional tooth extraction was needed and the type of definitive prosthesis was shifted from fixed type to removable one. Proper pre-surgical treatment planning is essential for the good prognosis. Implant-supported removable prosthesis on milled bars may be a useful treatment option in patients with incorrect angled placement on severely resorbed alveolar ridge.
Adult ; Alveolar Process ; Denture, Partial, Removable ; Humans ; Male ; Prognosis ; Prostheses and Implants ; Prosthodontics ; Tooth ; Tooth Extraction

No abstract available.
Animals ; Endometriosis* ; Female ; Horns* ; Kidney*

No abstract available.
Animals ; Endometriosis* ; Female ; Horns* ; Kidney*

No abstract available.
Animals ; Rats* ; Superoxides*

PURPOSE: We investigated the possible inhibitory effect of aspirin during the initiation and post initiating stages on N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) induced bladder carcinogenesis in female rats. MATERIALS AND METHODS: Forty-five female Sprague-Dawley rats were divided into three groups. Group A received 0.05% BBN in drinking water for 12 weeks. Group B re ceived 0.05% BBN in drinking water with 0.5% aspirin in the diet for 12 weeks. Group C received control diet without added chemicals. The rats were sacrificed after 12 weeks. For identification of chemopreventive effect of aspirin, apoptosis was detected by in situ cell death detection method. The apoptotic index (AI) was calculated from the ratio of typical apoptotic cells relative to the total cells from observation of at least 1000 cells in each preneoplastic lesion among the groups. RESULTS: All cases of group A showed multiple lesions of simple and focal hyperplasia. The incidence of papilloma was 80% in group A. All cases of group B also showed multiple lesions of simple and focal hyperplasia but the incidence of papilloma was decreased to 20%. The total numbers counted of focal hyperplasia and papilloma lesions were significantly reduced in group B than in group A (p<0.001 and p<0.001, respectively). The mean AI in group A and B sequentially increased in preneoplastic lesions, as compared to that in the normal epithelium of the rat bladder. Significant differences in AI in the lesions of simple and focal hyperplasia between group A and B were noted (p<0.001 and p<0.001, respectively). CONCLUSIONS: The result suggests that aspirin significantly decreases the incidence of precancerous lesions and it can act as a chemopreventive agent for precancerous lesions of urinary bladder.
Animals ; Apoptosis ; Aspirin* ; Carcinogenesis ; Cell Death ; Diet ; Drinking Water ; Epithelium ; Female ; Humans ; Hyperplasia ; Incidence ; Papilloma ; Rats* ; Rats, Sprague-Dawley ; Urinary Bladder Neoplasms ; Urinary Bladder*

OBJECTIVE: The loudness dependence of the auditory evoked potential (LDAEP) has been known as an indicator of central serotonergic neurotransmission. Nicotine increases the release of serotonin levels. The current study investigated whether cigarette smoking would make difference in LDAEP among male patients with major depressive disorder. METHODS: Twenty-four non-smoking and 20 smoking male patients meeting DSM-IV criteria for major depressive disorder (MDD) were recruited. There was no significant difference in severity of MDD symptoms between the two groups. The age of participants ranged from 20 to 65 years old. Event-related potentials (ERP) N100 were measured on 5 different sounds (55, 65, 75, 85, 95 dB) and on 5 electrodes (Fz, Cz, Pz, C5, C6). The N1/P2 peak to peak amplitudes and amplitude slope according to 5 different sounds were calculated. RESULTS: LDAEP was significantly weaker in the smoking group in comparison to the non-smoking group (p<0.05). Among non-smoking group LDAEP was negatively correlated with a core depression subscale of Hamilton Rating Scale for Depression (HAM-D) (r=-0.41, p<0.05). CONCLUSION: LDAEP of the smoking patients with MDD group was weaker than the non-smoking patient with MDD group's. This result suggests that smoking may have increased the release of serotonergic neurotransmission in patients with MDD. Future studies need to examine LDAEP changes before and after tobacco use among smoking patients.
Depression ; Depressive Disorder, Major ; Diagnostic and Statistical Manual of Mental Disorders ; Electrodes ; Evoked Potentials ; Evoked Potentials, Auditory ; Humans ; Male ; Nicotine ; Serotonin ; Smoke ; Smoking ; Synaptic Transmission ; Tobacco

PURPOSE: To evaluate the patterns of hemodynamic changes caused by various pathologic liver conditions. MATERIALS & METHODS: Combined CT hepatic arteriography(CTHA) and CT arterial portography(CTAP), performed in 185 consecutive patients, including 150 with hepatocellular carcinoma, were retrospectively analysed. Of these patients, 48 showed various patterns of hemodynamic change. such change caused by occlusion, stenosis and/or cavernous transformation of the portal vein, by occlusion or stenosis of the hepatic artery, or by the presence of arterioportal(AP) shunt could be classified as follows : type 1, decreased or absent portal flow ; type 2,decreased or absent hepatic arterial flow ; type 3, AP shunt without portal tumor thrombus(PTT) ; and type 4, PTT with transvasal AP shunt, including the presence of cavernous transformation of the portal vein. RESULTS: Type I (n=20) showed hyperattenuation of both PTT and absent portal flow area on CTHA, and reciprocally consistent hypoattenuation on CTAP. Type II (n=6) showed a hypoattenuating area on CTHA, and isoattenuation or slightly hyperattenuation on CTAP. Type III (n=9) showed an oval or wedge-shaped hyperattenuating area on CTHA, anddefective perfusion at the same area on CTAP. In Type IV (n=13), both CTHA and CTAP showed variable findings, according to the amount of transvasal AP shunt, the location and extent of PTT, and/or cavernous transformation ofthe portal vein. CONCLUSION: Pattern analyses of hemodynamic changes on both CTHA and CTAP are helpful inclarifying the primary causes of hemodynamic changes in the liver.
Angiography* ; Carcinoma, Hepatocellular ; Constriction, Pathologic ; Hemodynamics* ; Hepatic Artery ; Humans ; Liver* ; Perfusion ; Portal Vein ; Retrospective Studies

No abstract available.
Carcinoma, Squamous Cell* ; Colon* ; Colonic Polyps* ; Female* ; Humans ; Urethra*

BACKGROUND: Platelet activation has been implicated in the pathogenesis of a number of diseases, which include atherosclerosis, coronary vascular disease, and cerebrovascular disease. There have been controversies with the influence of hormone therapy on platelet activation. The purpose of this study was to define the effect of long-term hormone therapy on platelet activation. METHODS: We recruited a total of 162 postmenopausal women aged 55 and above among wihch eighty healthy postmenopausal women had received hormone therapy for more than 5 years and the remaining eighty- two healthy postmenopausal women with no hormone therapyapy. Baseline characteristics as well as the parameters related to platelet activation were compared between the two groups using T-test. After platelet activation was defined by the reference range, multivariated logistic regression analysis was performed determining the odds ratio of hormone therapy on platelet activation. RESULTS: The MPC and PCDW were significantly lower in the HT group than the Non-HT group (P<0.001), which suggests that platelets were more activated in the HT group more than in the non-HT group. Multiple logistic regression analysis showed that the odds ratio of the possibility of platelet activation in HT group was 19 times (P<0.001). CONCLUSION: Long term hormone therapy increased platelet activation significantly, which may be a contributing factor of thromboembolism.
Coronary Artery Disease ; Estrogens ; Female ; Humans ; Logistic Models ; Menopause ; Odds Ratio ; Platelet Activation* ; Reference Values ; Thromboembolism ; Vascular Diseases