Rabies is a fetal viral encephalitis to which all mammals, including man are susceptible. This virus, the genus of Rhabdovirus, is usually present in the saliva of infected animals and is transmitted by their bite. As a rule the virus enter the CNS by ascending along peripheral nervous system and extremely variable in extent. Negri bodies are appear in about 75% of cases. These bodies are eosinophilic, usually rounded inclusions and is located in the cystoplasm of the neurons, most frequently in the pyramidal neurons of the Hippocampus and the Purkinje cells of the cerebellum. We have experienced a case of canine rabies that showed Negri bodies in the Purkinje cells along with diffuse degenerative encephalitis and perivascular mononuclear cells infiltration. The Negri bodies were best demonstrated by Negri body staining although routine H-E staind was also useful. There inclusion bodies were located exclusively in the cytoplasm, and were found occasionally. Electron microscopic findings of the Negri bodies showed aggregates of bulletshaped nucleocapsids. We report a Negri body found in the brain of rabid dog with the light and electron microscopic findings.
Male ; Humans ; Dogs ; Animals

Orbital injuries are common with facial trauma. Direct injuries to the globe are not rare but it can result in complications such as chemosis, subconjunctival hemorrhage and hyphema. Periorbital trauma or injuries to the extraocular muscles and blow-out fracture may result in lid edema, ecchymosis & ptosis and diplopia or limitation of ocular motion respectively. Indirect injuries to the optic nerve come up without any injuries but its complication is irreversible and severe such as loss of vision. The aim of this study is to review the literature on blindness or ptosis following facial trauma and present the cases of blindness after facial trauma and ptosis after mandibular fracture without specific clinical findings.
Blindness ; Diplopia ; Ecchymosis ; Edema ; Hemorrhage ; Hyphema ; Mandibular Fractures ; Muscles ; Optic Nerve Injuries* ; Optic Nerve* ; Orbit ; Orbital Fractures

The purpose of this study was to investigate and evaluate what proportion is the characteristics in Korean dental arches with normal occlusion. Many others have already indicated Golden proportion in normal dental arches, but have not considered any racial and sociocultural differences. So the author postulated (radical2)n relations in Koreans. The materials were consisted of 134 dental casts with normal occlusion, which have never undergone orthodontic and prosthodontic procedures. Measurements were made on the arch dimensions using sliding caliper and data were computerized. The findings were as follows: 1. The width between the distal surfaces of the upper centrals, had (radical2)3 relation with the width between the buccal surfaces of the upper 1st premolars in Koreans. 2. The width between the distal surfaces of the lower laterals had (radical2) relation with the width between the distal surfaces of the lower canines, and had (radical2)2 relation with the distal surfaces of the upper centrals. 3. The width between the distal surfaces of the lower centrals had (radical2)2 relation with the width between the distal surfaces of the lower laterals, and had (radical2)3 relation with the width between the distal surfaces of the upper centrals.
Bicuspid ; Dental Arch* ; Prosthodontics

No abstract available.
Adult ; Hidradenitis ; Humans

Our Goal of modified segmental osteotomy on maxilla accompanied by mandibular anterior subapical osteotomy was to get the best results from patients of bi-alveolar or bi-maxillary protrusion. In this study, cephalornetric and photo (en face, profile) analysis have been compared to define the soft tissue change after surgery. Lip protrusion was efficiently reduced and nasolabial angle was much obtused Although nose was a little widened, it was quite acceptable. Blood circulation on osteotomized segment was well maintained This relatively simple methods could be successfully applied to many patients.
Blood Circulation ; Humans ; Lip ; Maxilla ; Nose ; Osteotomy*

Objectives: Alzheimer’s disease, a pervasive neurodegenerative disorder with global implications, links oral health conditions, such as edentulism and periodontitis, to cognitive impairment. This study aimed to objectively assess the oral health of 1,456 patients with dementia using panoramic imaging and explore potential associations between general health and anthropometric measurements. Methods: Patients’ panoramic images documented at Seoul St. Mary’s Hospital and Eunpyeong St. Mary’s Hospital during 2011-2020 were retrospectively scrutinized for oral health parameters. Data on general health, anthropometrics, and body mass index (BMI) were collected. The patients were categorized according to their remaining teeth, dental caries, presence of periodontitis, and BMI. Results: The average age was 74.20 years, and the average teeth number was 20.67. Significant differences in dental caries and periodontitis rates were observed across BMI categories. Younger age and female sex correlated with improved oral health. The underweight BMI group exhibited higher caries rates, whereas the average BMI group showed favorable outcomes for both caries and periodontitis. Conclusions Comprehensive analysis including panoramic imaging revealed notable associations between oral health and BMI in patients with dementia, emphasizing the importance of regular dental checkups. This study underscores the potential links between oral health and systemic conditions in dementia, necessitating further research to elucidate causal relationships and mechanisms.

This study was designed to evaluate the personality characteristics of orthognathic surgery patients preoperatively and postoperatively through the MMPI. Comparison was made between the personality characteritics of preoperative and postoperative groups. Motivation for undergoing orthognathic surgery and postoperative satisfaction were examined through the questionnaire. Subjects used in this study consisted of 50 patients under presurgical orthodontic treatment and 22 patients who had received orthognathic surgery. From this study, the results were followings. 1. In preoperative patients group, all T-scores were within the normal range except for K-scale. The T-score of K-scale is 57.7, this showed that these patients underwent some or less stress. 2. In postoperative patients group, all T-scores were within the normal range. 3. Only in K-scale, there was statistically significant increase after surgery (P<0.05). 4. In male patients group, all T-scores were within the normal range except for that of preoperative K-scale. Postoperatively, there were statistically significant increase in K and Hs scales(P<0.05) 5. In female patients group, all T-scores were within the normal range. 6. Motivation for undergoing orthognathic surgery could be divided into 4 categories: esthetic goal(28.2%), functional goal(32.1%), TMJ problem(9.0%), and psychosocial reason(30.7%). 7. The degree of postoperative satisfaction was quite high(85.7%). 14.3% of all patients were very satisfied, 71.49/o were satisfied, 9.5% were neither satisfied or dissatisfied, and 4.8% were very dissatisfied.
Female ; Humans ; Male ; MMPI* ; Motivation ; Orthognathic Surgery* ; Surveys and Questionnaires ; Reference Values ; Temporomandibular Joint

OBJECTIVES: The objective of this study is to determine the adequate concentration and to evaluate the osteogenic potential of simvastatin in human maxillary sinus membrane-derived stem cells (hSMSC). MATERIALS AND METHODS: Mesenchymal stem cells derived from the human maxillary sinus membrane were treated with various concentrations of simvastatin. The adequate concentration of simvastatin for osteogenic induction was determined using bone morphogenetic protein (BMP-2). The efficacy of osteogenic differentiation of simavastatin was verified using osteocalcin mRNA, and the mineralization efficacy of hSMSCs and simvastatin treatment was compared with alkaline phosphatase and von Kossa staining. RESULTS: Expression of BMP-2 mRNA and protein was observed after three days and was dependent on the concentration of simvastatin. Expression of osteocalcin mRNA was observed after three days in the 1.0 microM simvastatin-treated group. Mineralization was observed after three days in the simvastatin-treated group. CONCLUSION: These results suggest that simvastatin induces the osteogenic potential of mesenchymal stem cells derived from the human maxillary sinus membrane mucosa.
Adult ; Adult Stem Cells ; Alkaline Phosphatase ; Bone Morphogenetic Proteins ; Durapatite ; Humans ; Maxillary Sinus ; Membranes ; Mesenchymal Stromal Cells ; Mucous Membrane ; Osteocalcin ; RNA, Messenger ; Simvastatin ; Stem Cells

Purpose: . This study aims to evaluate the combined effect of reduced thickness in different regions on the fracture resistance of monolithic zirconia crowns. Materials and methods: . Seven nickel-chromium dies were generated from a 3D model of mandibular first molar using the digital scanner with the following geometries:1.5 mm occlusal reduction, 1.0 mm deep chamfer. Based on the abutment model, Zirconia blocks (Luxen Zirconia) were selected to fabricate Sixty-three zirconia crowns with occlusal thicknesses of 0.3 mm, 0.5 mm, and 1.5 mm, and different axial thicknesses of 0.3 mm, 0.5 mm, and 1.0 mm. All crowns were cemented by resin cement. Next, the crowns were subjected to load-to-fracture test until fracture using an electronic universal testing machine. In addition, fracture patterns were observed with a scanning electron microscope (SEM). Two-way ANOVA and the Tuckey HSD test for post hoc analysis were used for statistical analysis (P < .05). Results: . The mean values of fracture resistancerecorded was higher than the average biting force in the posterior region. The two-way ANOVA showed that the occlusal and axial thickness affected the fracture resistance significantly (P < .05). However, the effect of axial thickness on fracture resistance did not show a statistical difference when thicker than 0.5 mm. The observed failure modes were partial or complete fracture depending on the severity of crack propagation. Conclusion . Within the limitations of the present study, the CAD-CAM monolithic zirconia crown with extremely reduced thickness showed adequate fracture resistance to withstand occlusal load in molar regions. In addition, both occlusal and axial thickness affected the fracture resistance of the zirconia crown and showed different results as combined.

The purpose of this study was to evaluate the morphology of mandibular symphysis and location of lower incisor under the influence of the craniofacial skeleton in skeletal Class III malocclusion. The sample consisted of 132 adults who, have severe Class III malocclusion(prognathism group, 33 males and 33 females), and who have normal occlusion(normal group, 33 males and 33 females). They had not received any orthodontic treatment or orthognathic surgery. The, lateral cephalograms were evaluated. The results were as follows: 1. Prognathism group were larger than normal group in comparison of facial skeleton (p<0.05) with the exception of angle FH-Pal, angle SIN. 2. In the morphology of symphysis, measurements of anteroposterior width(LaABBW, LiABBW, SW) of prognathism group were significantly less than that of normal group(p<0.001). 3. In the correlative analysis between the craniofacial skeleton and symphysis measurements of prognathism group, vertical measurements in relation with cranial base and mandibular plane showed reverse correlationship with anteroposterior width of symphysis(LiACBW, LaACBW, LiABBW, SW)(p<0.05). But, there was not distinct difference between horizontal skeletal measurements and symphysis measurements (p>0.05). 4. The probability by regression test between vertical measurements(angle SN-Mn, angle FMA, angle Pal-Mn, angle LFH) and symphysis measurements(LiACBW, LiABBW, SW, angle LISA) were very high (p<0.001).
Adult ; Humans ; Incisor* ; Male ; Malocclusion* ; Orthognathic Surgery ; Prognathism ; Skeleton* ; Skull Base