Revascularization of immature necrotic teeth is a reliable treatment alternative to conventional apexogenesis or apexification. In case 1, a 12-year-old boy had his necrotic, immature mandibular left second premolar treated with a revascularization technique. At a24-month follow-up, periapical radiolucency had disappeared and thickening of the root wall was observed. In cases 2 and 3, a10-year-old boy had his necrotic, immature, bilateral mandibular second premolars treated with the same modality. At 48-month(in case 2) and 42-month (in case 3) follow-ups, loss of periapical radiolucencies and increases in the root wall thickness were also observed.
Apexification ; Bicuspid ; blood supply ; diagnostic imaging ; pathology ; surgery ; Child ; Dental Papilla ; blood supply ; drug effects ; pathology ; Dental Pulp ; blood supply ; drug effects ; pathology ; Dental Pulp Necrosis ; pathology ; therapy ; Follow-Up Studies ; Humans ; Male ; Mandible ; Neovascularization, Physiologic ; Radiography ; Regeneration ; Root Canal Irrigants ; therapeutic use ; Root Canal Therapy ; methods ; Tooth Apex ; blood supply ; diagnostic imaging ; Tooth, Deciduous ; blood supply ; pathology ; Treatment Outcome

Vivax malaria was endemic on the Korean peninsula for many centuries until the late 1970's when the Republic of Korea (ROK) was declared "malaria free". Since its re-emergence in 1993, the number of malaria cases in the military increased exponentially through 2000 near the demilitarized zone. Chemoprophylaxis with chloroquine and primaquine has been used in the ROK Army since 1997 in an attempt to reduce the number of the malaria cases throughout the ROK. Data show that chemoprophylaxis contributed, in part, to the decrease in the number of malaria cases among military personnel. However, mass chemoprophylaxis on a large scale in the ROK Army is unprecedented and extensive supervision and monitoring is warranted to determine its effectiveness and to monitor the appearance of chloroquine tolerant/resistant strains of Plasmodium vivax.
Antimalarials/therapeutic use ; Chemoprevention/methods/statistics and numerical data ; Chloroquine/*therapeutic use ; Disease Outbreaks/*prevention and control/*statistics and numerical data ; Humans ; Incidence ; Korea/epidemiology ; Malaria, Vivax/*epidemiology/*prevention and control ; Military Personnel/*statistics and numerical data ; Outcome Assessment (Health Care) ; Prevalence ; Primaquine/*therapeutic use ; Research Support, Non-U.S. Gov't ; Risk Assessment/methods ; Risk Factors ; Treatment Outcome