To investigate the occurrence and distribution of serotype, specific virulence genes, and pulse field gel electrophoresis (PFGE) patterns in Vibrio parahaemolyticus isolates from Jeonnam, Korea, we tested 87 strains which were identified with V. parahaemolyticus from diarrheal episode patients in 2005. In this study, 16 different O:K serotype combinations of V. parahaemolyticus were determined. The distributions of O and K serotypes were O4:K68 (51.72%), O1:K70 (18.39%), O3:K6 (5.74%), O1:K68 (4.60%) and O3:K57 (4.60%) respectively. Serotype O4:K68 was the regional dominant specific serotype of V. parahaemolyticus in Sinan of Jeonnam, Korea. For the detection of thermostable direct hemolysin (tdh) and TDH-related hemolysin (trh) gene of V. parahaemolyticus, PCR was performed. The tdh gene was detected in all of the V. parahaemolyticus isolates from diarrheal patients, but trh gene was not detected. Analysis of PFGE patterns of 30 V. parahaemolyticus isolates showed 3 groups and 20 types. Among 14 O4:K68 serotypes which were isolated in Sinan, PFGE patterns of 12 strains were closely related (100%), but 2 strains were related by 58.3% and 45.4%, respectively. Also two strains of O1:K4 serotype in Gurye and two strains of O3:K6 serotype in Yeosu were closely related (100%), respectively. Although serotypes (O1:K4, O1:K70, O3:K6 and O4:K68) were different, PFGE patterns were related for more than 80.9%. Therefore, the epidemiological surveillance of V. parahaemolyticus is required by PFGE typing scheme as a further diagnostic tool.
Bacterial Toxins ; Electrophoresis ; Hemolysin Proteins ; Humans ; Korea ; Polymerase Chain Reaction ; Serotyping ; Vibrio ; Vibrio parahaemolyticus

OBJECTIVE: This study was performed to evaluate the efficacy and safety of Trans-obturator tape (TOT) in the surgical treatment of stress incontinence and analyze the postoperative clinical outcome. METHODS: Between August 2004 and September 2005, females diagnosed as having stress incontinence (pure or mixed) were operated on using TOT. Eighty cases with more than three-month follow-up period were included for this study. RESULTS: Patient age ranged from 28 to 74 years (mean, 58). After surgical treatment using TOT, 74 cases (92.5%) of stress incontinence showed complete recovery, 4 cases (5%) showed partial recovery, and 2 cases (2.5%) were unchanged without further functional deterioration. Urgency in the mixed incontinence was improved in 30 in 36 cases (83.3%) and frequency was changed for the better in 20 of 27 cases (62.9%). The mean operation time was 14.3 minutes and the mean hospital stay was six hours. Postoperative evaluation with cystoscope was unnecessary. The postoperative complication rate was 10% (8/80). Postoperative wound bleeding occurred in one case and intraoperative bladder perforation happened in one case. Postoperative transient urgency was developed in one case and postoperative transient frequency developed in three cases. Two patients complained of weak urinary stream. CONCLUSION: The surgical treatment using TOT is thought to be a safe and efficient means for the outpatient management of stress incontinence. And also, this method appears to have an effect on urgency and frequency.
Cystoscopes ; Female ; Follow-Up Studies ; Hemorrhage ; Humans ; Length of Stay ; Outpatients ; Postoperative Complications ; Rivers ; Suburethral Slings* ; Urinary Bladder ; Wounds and Injuries

No abstract available.
Humans ; Hypersensitivity* ; Skin*

We report an autopsy case of neonatal giant cell hepatitis that was presumed to be related to bacterial sepsis, endotoxemia and to the subsequent parenteral alimentation and antibiotics treatment. The patient died of candidal endocarditis and multiple brain infarcts. This female baby was born by a normal full term spontaneous delivery. Six days after delivery she developed fever and lethargy as she suffered from Cheyne-Stokes respiration with severe grunting. Blood culture grew Enterobacter and Acinetobacter. After management of the sepsis her general condition improved. On the 23rd day of admission she was found to have deep jaundice and hepatosplenomegaly. The liver became larger progressively and the edge was palpable at the umbilical level. Grade II systolic murmur was heard along the left lower sternal border. She died on the 31st day of hospitalization. Postmortem examination showed severe jaundice, hepatosplenomegaly, a large vegetation on the mitral valve and multiple petechial hemorrhages of the viscera. Microscopically the liver showed features of massive giant cell transformation, mild fibrosis and inflammatory cells, suggestive of giant cell hepatitis. Numerous yeasts and candidal pseudohyphae were seen in the cardiac vegetation, focally extending into the myocardium. There was a focus of candidal vasculitis in the bowel wall. In addition there were multiple bilateral organizing infarcts in the cerebral hemisphere as well as diffuse white matter damage associated with septicemia.
Female ; Infant, Newborn ; Humans

Xeroderma pigmentosum is characterized by sunlight sensitivity, autosomal recessive inheritance, and multiple cutaneous malignant melanoma, angiosarcoma and fibrosarcoma. Some patient also demonstrate neurological manifestations, ie, mental deficiency, microcephaly, ataxia, choreoathetosis, and deafness. A 22 year old Korean soldier was seen at the Capital Armed Forces General Hospital in May of 1974 because of pigmentation and ulceration on the exposed area. Since the age of 3, the patient has suffered from freckles on exposed area and the lesions were gradually increased in number. About 3 years ago, he observed nodule on the left side of face, which underwent ulceration eventually. There were no history of unconsciousness, convulsion or other neurological symptoms. The histopathological picture in the margin of ulcerated lesion revealed hyperkeratosis and acanthosis in epidermis, and masses of various shaped and sized composed of basalioma cells in dermis. The peripheral cell layer of the tumor masses showed pallisade arrangement of the nuclei.
Arm ; Ataxia ; Deafness ; Dermis ; Epidermis ; Fibrosarcoma ; Hemangiosarcoma ; Hospitals, General ; Humans ; Ichthyosis* ; Intellectual Disability ; Melanoma ; Melanosis ; Microcephaly ; Military Personnel ; Neurologic Manifestations ; Pigmentation ; Seizures ; Sunlight ; Ulcer ; Unconsciousness ; Wills ; Xeroderma Pigmentosum* ; Young Adult

The Becker's nevus (pigmentary hairy edidermal nevus) is a variety of epidermal nevus in which epidermal thickening may be minimal, and hairiness and pigmentation obvious. Characteristically it is a unilateral lesion of the shoulder in males but it may affect other sites, be multiple and bilateral, and be found in women and negroes. Histologically nevus cells are not seen in the dermis. A man aged 25 had the nevus covering extensive area on his right shoulder since 2 years ago. The pigmentation was dark brownish and hairy. The pigmented area was noninfiltrated and in place showed perifollicular darkening. Coarse hairs were noticed since a year. ago. The histopathological picture showed hyperkeratosis, acanthosis, papillomatosis and increased melanin pigments in the basal cell layer. Nevus cells were not seen in the dermis.
African Continental Ancestry Group ; Dermis ; Female ; Hair ; Humans ; Male ; Melanins ; Nevus* ; Papilloma ; Pigmentation ; Shoulder

Rabies is a fetal viral encephalitis to which all mammals, including man are susceptible. This virus, the genus of Rhabdovirus, is usually present in the saliva of infected animals and is transmitted by their bite. As a rule the virus enter the CNS by ascending along peripheral nervous system and extremely variable in extent. Negri bodies are appear in about 75% of cases. These bodies are eosinophilic, usually rounded inclusions and is located in the cystoplasm of the neurons, most frequently in the pyramidal neurons of the Hippocampus and the Purkinje cells of the cerebellum. We have experienced a case of canine rabies that showed Negri bodies in the Purkinje cells along with diffuse degenerative encephalitis and perivascular mononuclear cells infiltration. The Negri bodies were best demonstrated by Negri body staining although routine H-E staind was also useful. There inclusion bodies were located exclusively in the cytoplasm, and were found occasionally. Electron microscopic findings of the Negri bodies showed aggregates of bulletshaped nucleocapsids. We report a Negri body found in the brain of rabid dog with the light and electron microscopic findings.
Male ; Humans ; Dogs ; Animals

Early gastric cancer is defined carcinoma that is limited to the gastric mucosa and submucosa and that does not extend into the muscularis propria. The development and widespread use of upper gnstrointestinal endoscopy with biopsy and cytology have enhanced our ability to make early diagnosis of gastrie carcinoma. Gastric cancinoma is being diagnosed at an ealry stage aad the survival rates for these patients are significantly greater than those with advanced gastric carcinoma. These ealry lesion can be cured in over 90% of the cases. In fact, it is almost impossible to follow up cases of early gastric cancer without surgical treatment. We report a case developed advanced gastric carcinoma 34 months after initial endoseopic diagnosis of early gastric cancer. A, 48-year-old woman was diagnosed early gaatrie cancer on June 21, 1985 by endoscopy. Proper surgical intetvention was not carried out due to her liver cirrhosis. The follow-up endoscopic examination was done on March 16, 1988. The gastric cancer looked like an advanced stomach and extended to other site.
Biopsy ; Diagnosis* ; Early Diagnosis ; Endoscopy ; Female ; Follow-Up Studies ; Gastric Mucosa ; Humans ; Liver Cirrhosis ; Middle Aged ; Stomach ; Stomach Neoplasms* ; Survival Rate

Taurodontism is an anomaly characterized by a long and broad pulpal cavity and consumed apical location of the furcation area. This study aimed to determine the prevalence of taurodontism in deciduous molars based on digital panoramic radiographs of children. The study was performed on a sample of panoramic radiographs taken from 2,473 Korean children who visited the department of pediatric dentistry, Yonsei University Dental Hospital between Nov. 2005 and Mar. 2018. Taurodontism was mainly categorized by Daito’s method. Using panoramic radiographs, taurodontism was also categorized into mesotaurodontism, hypotaurodontism, and hypertaurodontism. Mesotaurodontism was the most prevalent type. A total of 2,473 panoramic radiographs were evaluated. The prevalence of taurodontism was 5.7% in general, 51.5% in the left quadrant, 48.5% in the right quadrant, 6.3% in the maxilla, and 93.7% in the mandible. The distribution of taurodontism stratified by gender showed a higher prevalence in males. This is a comprehensive study on the prevalence of taurodontism in children using the largest sample size to date.

No abstract available.