1.Osteochondrodysplasia Pathologic study of 29 autopsy cases.
Yi Kyeong CHUN ; Yee Jeong KIM ; Sung Ran HONG ; Min Suk KIM ; Je G CHI
Korean Journal of Pathology 1999;33(1):32-41
Osteochondrodysplasia is a heterogeneous group of disorders appearing short limbed dwarfism. Because many of these entities are lethal and hereditary, an accurate diagnosis is mandatory. The purpose of this study is to define the clinicopathologic features and radiologic findings of osteochondrodysplasia. We reviewed 29 autopsy cases of congenital short limbed dwarfism, consisting of thanatophoric dysplasia (TD) (12 cases), osteogenesis imperfecta (OI) (12 cases), asphyxiating thoracic dysplasia (ATD) (3 cases), short-rib-polydactyly syndrome (SRPS) (1 case) and hypochondrogenesis (1 case). The gestational age ranged from 16 to 41 weeks. Of 6 fetuses that were born alive, 3 were ATD, 2 were TD and 1 was hypochondrogenesis. TD was frequently complicated by hydramnios. Of 8 cases studied chromosomally, only 1 showed chromosomal abnormality -46XY, inv 9. Intrauterine growth retardation was frequently associated with OI. Pulmonary hypoplasia was present in 23 cases (79%), including all cases of ATD, SRPS and hypochondrogenesis, 11 in TD and 7 in OI. Other associated anomalies were present in 17 cases (59%).
Autopsy*
;
Chromosome Aberrations
;
Diagnosis
;
Dwarfism
;
Extremities
;
Fetal Growth Retardation
;
Fetus
;
Gestational Age
;
Osteochondrodysplasias*
;
Osteogenesis Imperfecta
;
Polyhydramnios
;
Thanatophoric Dysplasia
2.Clinical and laboratory characterization of hybrid leukemias.
Seonyang PARK ; Je Hwan LEE ; Sung Hyun YANG ; Myoung Hee PARK ; Nyeong Kook KIM ; Han Ik CHO ; Noe Kyeong KIM
Korean Journal of Hematology 1992;27(2):261-272
No abstract available.
Leukemia*
3.Absence of the Septum Pellucidum Associated with a Midline Fornical Nodule and Ventriculomegaly: A Report of Two Cases.
Yi Kyeong CHUN ; Hye Sun KIM ; Sung Ran HONG ; Je G CHI
Journal of Korean Medical Science 2010;25(6):970-973
We report two autopsy cases that revealed the partial absence of the septum pellucidum with ventriculomegaly. In each case, the brain showed mild dilatation of both frontal horns of the lateral ventricles, normal third and fourth ventricles and no aqueductal stenosis. The posterior portion of the septum pellucidum was absent and the fornices were fused in a single midline nodule, abnormally displaced to a caudal position and lodged in the foramina of Monro. The brain base showed no apparent abnormalities; the optic nerves were well developed. We conclude that the caudally displaced fornix in the absence of the septum pellucidum may have intermittently obstructed the foramina of Monro and induced mild ventriculomegaly.
4.A Case of Amisulpride Induced Tardive Blepharospasm in Schizophrenia.
Wu Ri PARK ; Sung Whoi KONG ; Je Chun YU ; Chang Hwa LEE ; Kyeong Sook CHOI
Korean Journal of Psychopharmacology 2012;23(3):122-125
Tardive blepharospam is characterized by repetitive, forceful, and sustained involuntary contractions of the orbicularis oculi. We report here one case of neuroleptic-induced tardive blepharospasm that developed during high-dose amisulpride treatment and was treated with clozapine. The patient was a 29-year-old man with a 6-year history of schizophrenia. After 33 months of amisulpride treatment (1200 mg/day), involuntary eye-blinking had developed. Following exclusion of all other possible etiopathological causes of the blepharospasm, we decided to switch the drug treatment from amisulpride to clozapine. On the fourteenth day of clozapine (250 mg/day) treatment, we observed significant improvements in eye-blinking and psychotic symptoms. Four months later, the eye-blinking had remitted completely. We suggest that amisulpride may cause blepharospasm and lead to an impaired ability to perform daily activities. Therefore, we recommend that clinicians regularly monitor involuntary movements in patients receiving antipsychotic treatment, especially when high doses of amisulpride are involved.
Adult
;
Blepharospasm
;
Clozapine
;
Contracts
;
Dyskinesias
;
Humans
;
Organothiophosphorus Compounds
;
Schizophrenia
;
Sulpiride
5.Management of Cecal Diverticulitis.
Jong Je SUNG ; Dan SONG ; Gaun Yue HONG ; Nae Kyeong PARK
Journal of the Korean Society of Coloproctology 2004;20(5):251-256
PURPOSE: Diverticular disease of the cecum and ascending colon is a relatively uncommon disease, and is often difficult to diagnose. The purpose of this study was to investigate the clinical features of patients who underwent surgical treatment for cecal diverticulitis. METHODS: A retrospective review was conducted between January 1998 and December 2002 of 44 patients treated at the Department of Surgery, Soonchunghyang Gumi Hospital. RESULTS: All patients presented with right lower quadrant pain and tenderness. Preoperatively, 34 patients were diagnosed with acute appendicitis. The surgical procedures for cecal diverticulitis were an appendectomy only (5 cases), a diverticulectomy with appendectomy (31 cases), and a right hemicolectomy (8 cases). Postoperative complications were found in 17 cases: wound infection (13 cases), and partial intestinal obstruction (2 cases). CONCLUSIONS: When cecal diverticulitis is found at the time of an operation, surgical management is a safe treatment with low morbidity and a low recurrence rate. A diverticulectomy with appendectomy is a safe and effective procedure for the treatment of cecal diverticulitis if there is no evidence of free perforation or abscess formation. If the diverticulitis is complicated, undistinguishable from a malignancy, a resection (ileocecal resection, right hemicolectomy) should be considered for the surgical treatment.
Abscess
;
Appendectomy
;
Appendicitis
;
Cecum
;
Colon, Ascending
;
Diverticulitis*
;
Gyeongsangbuk-do
;
Humans
;
Intestinal Obstruction
;
Postoperative Complications
;
Recurrence
;
Retrospective Studies
;
Wound Infection
6.Selective arterial embolization of renal arteriovenous fistula after renal biopsy : A case report and review of litertures.
Kyeong Mi LEE ; Je Yol OH ; Jong Hun PARK ; U Chang CHOI ; Sung Kyu HA ; Dong Ik KIM ; Ki Whang KIM
Korean Journal of Nephrology 1993;12(2):194-198
No abstract available.
Arteriovenous Fistula*
;
Biopsy*
7.Localization and expression of LHRH mRNA and its local action in the rat testis.
Wan Sung CHOI ; In Yeap LEE ; Myeong Ok KIM ; Jeoung Sook LEE ; Hyung Chae KANG ; Hyun Joon SOHN ; Kyeong Je CHO ; Bong Hee LEE ; Sang Ho BAIK
Korean Journal of Anatomy 1992;25(4):370-383
No abstract available.
Animals
;
Gonadotropin-Releasing Hormone*
;
Rats*
;
RNA, Messenger*
;
Testis*
8.Study on neural axis of rat uterus using pseudorabies virus.
Bong Hee LEE ; Wan Sung CHOI ; Kyeong Je CHO ; hae Young KWON ; Ji Hong BAE ; Jun Kyung SONG ; Heung Shik LEE ; Sang Ho BAIK
Korean Journal of Anatomy 1993;26(3):225-234
No abstract available.
Animals
;
Axis, Cervical Vertebra*
;
Herpesvirus 1, Suid*
;
Pseudorabies*
;
Rats*
;
Uterus*
9.Survey of Adverse Events After The First Dose of The ChAdOx1 nCoV-19 Vaccine:A Single-Center Experience in Korea
Je Eun SONG ; Gang-Bok OH ; Hye Kyeong PARK ; Sung-Soon LEE ; Yee Gyung KWAK
Infection and Chemotherapy 2021;53(3):557-561
Vaccination is an important strategy for controlling the coronavirus disease 2019 (COVID-19) pandemic. We conducted a web-based cross-sectional survey based on Google Forms to collect data on adverse events (AEs) after the first dose of the ChAdOx1 nCoV-19 vaccine for healthcare workers (HCWs). Among the 1,676 vaccinated HCWs, 59.5% (998/1,676) responded to the survey. In total, 809 (81.1%) respondents reported experiencing AEs. There were no serious AEs, such as anaphylaxis. The most common AE was pain at the injection site (76.2%), followed by fatigue (75.9%), myalgia (74.9%), and fever (58.4%). HCWs in the younger age group experienced significantly more AEs than in the older age group.
10.Survey of Adverse Events After The First Dose of The ChAdOx1 nCoV-19 Vaccine:A Single-Center Experience in Korea
Je Eun SONG ; Gang-Bok OH ; Hye Kyeong PARK ; Sung-Soon LEE ; Yee Gyung KWAK
Infection and Chemotherapy 2021;53(3):557-561
Vaccination is an important strategy for controlling the coronavirus disease 2019 (COVID-19) pandemic. We conducted a web-based cross-sectional survey based on Google Forms to collect data on adverse events (AEs) after the first dose of the ChAdOx1 nCoV-19 vaccine for healthcare workers (HCWs). Among the 1,676 vaccinated HCWs, 59.5% (998/1,676) responded to the survey. In total, 809 (81.1%) respondents reported experiencing AEs. There were no serious AEs, such as anaphylaxis. The most common AE was pain at the injection site (76.2%), followed by fatigue (75.9%), myalgia (74.9%), and fever (58.4%). HCWs in the younger age group experienced significantly more AEs than in the older age group.