1.Continuous culture of recombinant mammalian cells producing hepatitis B virus surface antigen in stirred tank reactor equipped with a cell sedimentation column.
Suk Hoon HA ; Tae Wook HAHN ; Ree Ann YOO ; Wan Je PARK ; Hyun Su KIM
Journal of the Korean Society of Virology 1992;22(1):77-80
No abstract available.
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
2.Immunogenicity from polio/hepatitis B chimeric virus.
Tae Wook HAN ; Ree Ann YOO ; Suk Hoon HA ; Wan Je PARK ; Hyun Su KIM
Journal of the Korean Society of Virology 1992;22(2):111-117
No abstract available.
3.The One-Year Prognostic Value of the Pre-Discharge ECG after the First Acute Myocardial Infarction.
Yeong Ho CHOI ; Suck Koo CHOI ; Won Sang YOO ; Hyun Je LEE
Korean Circulation Journal 1988;18(1):41-47
To assess the prognostic value of the 14 ECG variables obtained from the pre-discharge ECG, 35 patients were followed up for at least one year among the 80 patients of the acute myocardial infarction admitted at Seoul Paik Hospital from Sep. 1983 to Aug. 1986. The following results were obtained. 1) The overall in-hospital mortality rate was 20% and the mortality rate tended to decline year by year. 2) The one-year mortality and morbidity rate of the followed patients was 31.4%. 3) Among the 14 variables obtained from the pre-discharge ECG, T-negativity was the only statistically significant (p<0.05) one to predict the one-year prognosis in the patients after the first myocardial infarction, and we could not derive any meaningful datd from the analysis of the combined effects of the three ECG variables (PTF, ST depression and ST elevation).
Depression
;
Electrocardiography*
;
Hospital Mortality
;
Humans
;
Mortality
;
Myocardial Infarction*
;
Prognosis
;
Seoul
4.CAM 5.2 Positive Cells in the Epidermis of Nevus Sebaceus.
Young Gull KIM ; Kwang Hyun CHO ; Yoo Shin LEE ; Je Geun CHI
Annals of Dermatology 1993;5(1):5-8
BACKGROUND: In the course of the study of keratin expression in the epidermis of nevus sebaceus, several cells in the epidermis of nevus sebaceus were positively stained with CAM 5.2 antibody, which is known to be specific for the lower molecular weight cytokeratin and used as a marker of Merkel cell. OBJECTIVE: This study was intended to verify that CAM 5.2 positive cells found in the epidermis of nevus sebaceus are Merkel cells and to understand the meaning of CAM 5.2 positive j cells in the epidermis of nevus sebaceus. METHODS: The immunohistochemical stainings with CAM 5.2 and antibody to epithelial membrane antigen (EMA) performed on specimens of normal skin, epidermal nevus, nevus sebaceus and some appendage tumors. In order to confirm the nature of CAM 5.2 positive cells, the distribution of those were compared to that of Merkel cells and double labeling with CAM 5.2 and neurofilament was performed. RESULTS: CAM 5.2 positive cells were also found in trichilemmoma developed associated with nevus sebaceus and the epidermis of normal paimoplantar skin. CAM 5.2 positive cells were also stained with antibody to EMA on serial sections cut from the same tissue blocks. The association of CAM 5.2 positive cell and nerve fiber was also demonstrated. CONCLUSION: CAM 5.2 positive cells are seemed to be Merkel cells and their presence in the covering epidermis of nevus sebaceus suggests to the epidermis of nevus sebaceus may not be nevoid proliferation of epidermal keratinocytes.
Epidermis*
;
Intermediate Filaments
;
Keratinocytes
;
Keratins
;
Merkel Cells
;
Molecular Weight
;
Mucin-1
;
Nerve Fibers
;
Nevus*
;
Skin
5.CAM 5.2 Positive Cells in the Epidermis of Nevus Sebaceus.
Young Gull KIM ; Kwang Hyun CHO ; Yoo Shin LEE ; Je Geun CHI
Annals of Dermatology 1993;5(1):5-8
BACKGROUND: In the course of the study of keratin expression in the epidermis of nevus sebaceus, several cells in the epidermis of nevus sebaceus were positively stained with CAM 5.2 antibody, which is known to be specific for the lower molecular weight cytokeratin and used as a marker of Merkel cell. OBJECTIVE: This study was intended to verify that CAM 5.2 positive cells found in the epidermis of nevus sebaceus are Merkel cells and to understand the meaning of CAM 5.2 positive j cells in the epidermis of nevus sebaceus. METHODS: The immunohistochemical stainings with CAM 5.2 and antibody to epithelial membrane antigen (EMA) performed on specimens of normal skin, epidermal nevus, nevus sebaceus and some appendage tumors. In order to confirm the nature of CAM 5.2 positive cells, the distribution of those were compared to that of Merkel cells and double labeling with CAM 5.2 and neurofilament was performed. RESULTS: CAM 5.2 positive cells were also found in trichilemmoma developed associated with nevus sebaceus and the epidermis of normal paimoplantar skin. CAM 5.2 positive cells were also stained with antibody to EMA on serial sections cut from the same tissue blocks. The association of CAM 5.2 positive cell and nerve fiber was also demonstrated. CONCLUSION: CAM 5.2 positive cells are seemed to be Merkel cells and their presence in the covering epidermis of nevus sebaceus suggests to the epidermis of nevus sebaceus may not be nevoid proliferation of epidermal keratinocytes.
Epidermis*
;
Intermediate Filaments
;
Keratinocytes
;
Keratins
;
Merkel Cells
;
Molecular Weight
;
Mucin-1
;
Nerve Fibers
;
Nevus*
;
Skin
6.Bone Ingrowth into Harris-Galante Porous-coated Acetabular Cup Retrieved during Revision.
Jun Dong CHANG ; Je Hyun YOO ; Yong Hyuk CHOI ; Chang Ju LEE
Journal of the Korean Hip Society 2006;18(1):12-17
Purpose: To investigate the extent of bone ingrowth into the porous-coated acetabular cups as well as the factors that correlated with bone ingrowth in total hip arthroplasty. Materials and Methods: Thirty six Harris-Galante porous-coated acetabular cups that were retrieved through revision surgery were examined in this study. Acetabular cups retrieved due to infection or severely destroyed cups (ed note: severe what?) were excluded. The extent of bone ingrowth into the acetabular cups was grossly measured, and its correlation with the variables including age, gender, weight, height, the duration of fixation, size, number of screws, inclination and anteversion was statistically analyzed. Results: The mean proportion of bone ingrowth was 52.9 21.9%(2~90%) and less than 30% in three cups(8.3%). The pattern and the location of bone ingrowth were not consistent. There was no correlation between the extent of bone ingrowth and age, gender, weight, height, the duration of fixation, cup size, number of screws, size, inclination and anteversion. Conclusion: Harris-Galante porous-coated acetabular cups showed satisfactory bone ingrowth regardless of the variables associated with the demographic or surgical conditions. Surface treatments with a fiber-metal porouscoating appears to be suitable for cementless acetabular cups in terms of the long term results.
Acetabulum*
;
Arthroplasty, Replacement, Hip
7.Fine Needle Aspiration Cytologic Findings of Kikuchi's Lymphadenitis: Analysis of 30 cases.
Hyun Ju YOO ; Hye Je CHO ; Ill Hyang KO
Korean Journal of Cytopathology 1994;5(2):113-119
Thirty cases of kikuchi's lymphadenitis, diagnosed by fine needle aspiration cytology, were reviewed to determine the main cytologic features helpful in reaching a diagnosis. The patients(mean age 26.6 years. male: female=1:3.8) presented with lymphadenopathy(cervical 24, submandibular 3, and axillary 1) with or without fever and local tenderness. Excisional biopsy was done for confirmation in 5 cases and the remaining 25 cases showed the similar cytologic and clinical features. In the aspiration smears of all cases. there was a heterogenous cellular mixture including frequent extracellular karyorrhectic nuclear debris, phagocytic histiocytes, plasmacy toid monocytes, and a variable number of polymorphous lymphocytes such as immunoblasts. activated large lymphocytes, and small mature lymphocytes, The characteristic cytologic features of kikuchi's lymphadenitis were the following: (1) frequent extracelluar karyorrhectic nuclear debris in the background: (2) phagocytic histiocytes with eccentrically placed crescentic nuclei and abundant pale cytoplasm containing phagocytized karyorrhectic debris: (3) plasmacytoid monocytes, which were medium-sized cells with eccentrically placed round nuclei and amphophilic cytoplasm: (4) no neutrophilic background.
Biopsy
;
Biopsy, Fine-Needle*
;
Cytoplasm
;
Diagnosis
;
Fever
;
Histiocytes
;
Humans
;
Lymphadenitis*
;
Lymphocytes
;
Male
;
Monocytes
;
Neutrophils
8.Locked Plating in Elderly Patients with Distal Femur Fracture: How to Avoid Complications?
Journal of the Korean Fracture Society 2019;32(2):112-119
Distal femur fractures in elderly patients with osteoporosis are complicated because poor bone quality makes screw purchase and fixation less secure, presenting many clinical challenges to the orthopedic surgeon. Minimally invasive locked plating using an angularly stable locking compression plate has become an integral tool for achieving secure fixation in osteoporotic distal femur fractures with improved biomechanical performance. On the other hand, complications, such as implant failure and periplate fracture, have still occurred. This paper describes the principles of internal fixation in minimally invasive lateral locked plating in elderly patients with osteoporotic distal femur fractures as well as how to avoid complications.
Aged
;
Femur
;
Hand
;
Humans
;
Orthopedics
;
Osteoporosis
;
Osteoporotic Fractures
9.The Effects of Pre-operative Visual Information and Parental Presence Intervention on Anxiety, Delirium, and Pain of Post-Operative Pediatric Patients in PACU.
Je Bog YOO ; Min Jung KIM ; Soo Hyun CHO ; Yoo Jung SHIN ; Nam Cho KIM
Journal of Korean Academy of Nursing 2012;42(3):333-341
PURPOSE: The purpose of this study was to test whether pre-operative visual information and parental presence had positive effects on anxiety, delirium, and pain in pediatric patients who awoke from general anesthesia in a post-surgical stage. METHODS: This study used a non equivalent control-group post test design (n=76). Independent variables were provision of pre-operative visual information and parental presence for post-surgical pediatric patients in PACU (post anesthesia care unit). Dependent variables were anxiety, delirium, and pain in the pediatric patients measured three times at 10 minute intervals after extubation in the PACU. Measurements included Numerical Rating Scale for assessing state anxiety, Pediatric Anesthesia Emergence Delirium Scale by Sikich & Lerman (2004) for delirium, and Objective Pain Scale by Broadman, Rice & Hannallah (1988) for pain. RESULTS: Experimental group showed significantly decreased state anxiety at time points-10, 20, and 30 minutes after extubation. Delirium was significantly lower at 10 minutes and 30 minutes after extubation in the experimental group. Pain was significantly lower at 10 minutes after extubation in the experimental group. CONCLUSION: The results of this study suggest that this intervention can be a safe pre-operative nursing intervention for post-surgical pediatric patients at PACU.
Adolescent
;
Anesthesia Recovery Period
;
Anesthesia, General
;
*Anxiety
;
Child
;
*Delirium
;
Female
;
Humans
;
Male
;
*Pain
;
*Pain Measurement
;
Parents
;
Patient Education as Topic
;
Postanesthesia Nursing
;
Preoperative Care
;
Recovery Room
10.Separate Vertical Wiring for the Fixation of Comminuted Fractures of the Inferior Pole of the Patella.
Hyung Keun SONG ; Je Hyun YOO ; Young Soo BYUN ; Kyu Hyun YANG
Yonsei Medical Journal 2014;55(3):785-791
PURPOSE: Among patients over 50 years of age, separate vertical wiring alone may be insufficient for fixation of fractures of the inferior pole of the patella. Therefore, mechanical and clinical studies were performed in patients over the age of 50 to test the strength of augmentation of separate vertical wiring with cerclage wire (i.e., combined technique). MATERIALS AND METHODS: Multiple osteotomies were performed to create four-part fractures in the inferior poles of eight pairs of cadaveric patellae. One patella from each pair was fixed with the separate wiring technique, while the other patella was fixed with a combined technique. The ultimate load to failure and stiffness of the fixation were subsequently measured. In a clinical study of 21 patients (average age of 64 years), comminuted fractures of the inferior pole of the patellae were treated using the combined technique. Operative parameters were recorded from which post-operative outcomes were evaluated. RESULTS: For cadaveric patellae, whose mean age was 69 years, the mean ultimate loads to failure for the separate vertical wiring technique and the combined technique were 216.4+/-72.4 N and 324.9+/-50.6 N, respectively (p=0.012). The mean stiffness for the separate vertical wiring technique and the combined technique was 241.1+/-68.5 N/mm and 340.8+/-45.3 N/mm, respectively (p=0.012). In the clinical study, the mean clinical score at final follow-up was 28.1 points. CONCLUSION: Augmentation of separate vertical wiring with cerclage wire provides enough strength for protected early exercise of the knee joint and uneventful healing.
Aged
;
Aged, 80 and over
;
*Bone Wires
;
Female
;
Fracture Fixation, Internal/methods
;
Fractures, Comminuted/*surgery
;
Humans
;
Male
;
Middle Aged
;
Osteotomy
;
Patella/*injuries/*surgery