1.Disseminated trichosporon beigelii infection.
Sook In JUNG ; Je Jung LEE ; Ik Joo CHUNG ; Hyeoung Joon KIM ; Jong Hee SHIN ; Dong Hyeon SHIN
Korean Journal of Medicine 2003;65(2):261-262
No abstract available.
Trichosporon*
2.Heterophyid metacercarial infections in brackish water fishes from Jinju-man (Bay), Kyongsangnam-do, Korea.
Do Gyun KIM ; Tong Soo KIM ; Shin Hyeong CHO ; Hyeon Je SONG ; Woon Mok SOHN
The Korean Journal of Parasitology 2006;44(1):7-13
Heterophyid metacercarial infections in brackish water fishes, i.e., perch, shad, mullet, redlip mullet, and goby, of Jinju-man (Bay), Kyongsangnam-do, Korea, were investigated using a digestion technique. Among 45 perch (Lateolabrax japonicus), the metacercariae of Heterophyopsis continua were found in 55.6% (18.5 metacercariae per fish), Stictodora spp. in 28.9% (3.6), and Metagonimus takahashii in 6.7% (17.0). The metacercariae of H. continua were detected in 23 (65.7%) of 35 shad (Konosirus punctatus). Among 15 mullet (Mugil cephalus), the metacercariae of Pygidiopsis summa were found in 100% (105.9 metacercariae per fish), Heterophyes nocens in 40.0% (8.5), H. continua in 13.3%, and Stictodora spp. in 6.7%. Among 12 redlip mullet (Chelon haematocheilus), the metacercariae of P. summa were detected in 91.7% (1,299 metacercariae per fish), H. nocens in 16.7%, and Stictodora spp. in 16.7%. Among 35 gobies (Acanthogobius flavimanus), the metacercariae of Stictodora spp. were found in 82.9% (44.5 metacercariae per fish), and H. continua in 25.7% (2.8). The adult flukes recovered from a cat experimentally infected with metacercariae from perches were compatible with M. takahashii. The results confirm that the estuarine fish in Jinju-man (Bay) are heavily infected with heterophyid metacercariae. Furthermore, it was found for the first time that the perch acts as a second intermediate host for M. takahashii.
Trematode Infections/epidemiology/parasitology/*veterinary
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Seawater
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Prevalence
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Life Cycle Stages
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Korea/epidemiology
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Heterophyidae/anatomy & histology/*isolation & purification
;
Fishes
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Fish Diseases/*epidemiology/*parasitology
;
Cats
;
Animals
3.Ultrasound-guided central cluster approach for the supraclavicular brachial plexus block: a case series.
Mi Geum LEE ; Kyung Cheon LEE ; Hong Soon KIM ; Seol Ju PARK ; Young Je SUH ; Hyeon Ju SHIN
Korean Journal of Anesthesiology 2015;68(6):603-607
There are many different approaches to ultrasound-guided supraclavicular brachial plexus block (US-SCBPB), and each has a different success rate and complications. The most commonly performed US-SCBPB is the corner pocket approach in which the needle is advanced very close to the subclavian artery and pleura. Therefore, it may be associated with a risk of subclavian artery puncture or pneumothorax. We advanced the needle into the central part of the neural cluster after penetrating the sheath of the brachial plexus in US-SCBPB. We refer to this new method as the "central cluster approach." In this approach, the needle does not have to advance close to the subclavian artery or pleura. The aim of this study was to evaluate the clinical outcomes of the central cluster approach in US-SCBPB.
Brachial Plexus*
;
Needles
;
Pleura
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Pneumothorax
;
Punctures
;
Subclavian Artery
;
Ultrasonography
4.Prevalence and Antimicrobial Susceptibility of Campylobacter coli Isolates from Swine.
Shin Moo KIM ; Mi Rae CHOI ; Pil Seung KWON ; Hyeon Je SONG ; In Ho JANG ; Yunsop CHONG
Journal of Bacteriology and Virology 2011;41(1):27-35
Swine is a common source of Campylobacter coli human gastroenteritis, for the treatment of which erythromycin and fluoroquinolones are recommended. The prevalence of antimicrobial-resistant C. coli differs significantly depending on countries. We investigated the prevalence of C. coli in swine from a farm in Buan-gun, Korea in 2010, and determined antimicrobial susceptibility of the isolates. Rectal swab specimens were used to inoculate Campylobacter Preston media and incubated microaerophilically at 42degrees C for 48 h. The species were identified by phenotypic tests and by detecting hipO and glyA genes. PCR was used to detect mutations of A2074C in 23S rRNA gene, and quinolone resistance-determining region (QRDR) of gyrA, which are associated with high level resistance to erythromycin, and with ciprofloxacin, respectively. Antimicrobial susceptibility was determined by the disk diffusion and agar dilution tests. Of the 100 specimens, 55 (55%) yielded C. coli, and 23 of them (41.8%) had A2074G mutation. A2074G mutated isolates showed the lowest MIC90 of imipenem, while those of ampicillin and clindamycin were relatively low. The majority of both A2074G mutation-positive and -negative isolate were susceptible to ampicillin, cefotaxime, and chloramphenicol. All isolates were resistant to ciprofloxacin, and had mutation in QRDR of gyrA. In conclusion, C. coli was detected in 55% of swine, and A2074G mutation was detected in 41.8% of the isolates. All isolates had gyrA mutation-mediated ciprofloxacin resistance.
Agar
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Ampicillin
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Campylobacter
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Campylobacter coli
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Cefotaxime
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Chloramphenicol
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Ciprofloxacin
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Clindamycin
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Diffusion
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Erythromycin
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Fluoroquinolones
;
Gastroenteritis
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Genes, rRNA
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Humans
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Imipenem
;
Korea
;
Polymerase Chain Reaction
;
Prevalence
;
Swine
5.Epidemiological Survey of Hantaan Virus Infection of Wild Rodents Trapped in Jeollanam-do, 2003~2004.
Hyeon Je SONG ; Dae Yeon LEE ; Choong Mo KIM ; Young Hack SHIN
Journal of Bacteriology and Virology 2006;36(3):205-210
Hantaan virus (HTNV) is widely distributed in Korea and has been known to cause haemorrhagic fever with renal syndrome (HFRS). Hantaviruses are carried by numerous rodent species throughout the world. Especially, the stripedfield mice, Apodemus agrarius, is the natural host for Hantaan virus in Korea, In this study, a total 117 wild rodents of 2 species (A. agrarius, Crocidura laciura) were trapped from six county (Damyang- gun, Hwasun-gun, Gokseong-gun, Jangheung-gun, Hampyeong-gun and Boseong-gun) in Jeonnam province from Sep. 2003 to Nov. 2004 for epidemiological survey. As determined by the indirect immunofluorescent antibody (IFA) test, IgG antibodies against HTNV were detected in 13.4% (14/103) of A. agrarius captured on above the areas. Serologic evidence for HTNV infection was not found in 14 C. laciura. 5 of A. agrarius were positive of hantaan viral RNA amplication from lung tissue of 14 seropositive A. agrarius by RT-PCR. For isolation of the hantaan virus, the lung tissue homogenate of 14 seropositive A. agrarius inoculated Vero E6 cells, but virus was not isolated.
Animals
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Antibodies
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Fever
;
Hantaan virus*
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Hantavirus
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Immunoglobulin G
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Jeollanam-do*
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Korea
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Lung
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Mice
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Murinae
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RNA, Viral
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Rodentia*
6.Development and Effectiveness of Non-Suicidal Self-Injury Prevention Program for Adolescents Using Brief Dialectical Behavioral Therapy Skills Training (DBT-ST)
Jonggook LEE ; Gyeong-min KIM ; Okran JANG ; Byeonguk PARK ; Hyunjeong KIM ; Gyeongmi HYEON ; Cheolgyu SHIN ; Je Jung LEE
Journal of Korean Neuropsychiatric Association 2023;62(3):102-110
Objectives:
The purpose of this study was to develop a non-suicidal self-injury (NSSI) prevention program for adolescents and confirm its effectiveness in primary prevention by applying dialectical behavior therapy skills training (DBT-ST).
Methods:
From September to December 2021, 217 first-year students in three middle schools in the Chungcheong Province were tested for changes from before and after the program using the Responses to Depressed Mood Questionnaire and Difficulties in Emotion Regulation Scale-16 using paired t-tests. McNemar’s test was conducted to confirm the changes in the perception and attitude scale of NSSI for each question.
Results:
A comparison of the changes from before and after the program revealed that the response to depressed mood (t=7.93, p<0.001), ruminant response (t=5.18, p<0.001), and distractive response (t=6.07, p<0.001) which are subfactors of the response to depressive moods, were significantly affected. There was a significant decrease in the difficulty in performing goaloriented behavior (t=3.34, p=0.01) and lack of emotional clarity (t=2.52, p=0.012), which are subfactors of emotional regulation difficulties. Also, in the comparison of the perception and attitude towards NSSI, statistically significant changes were confirmed in 7 out of a total of 9 questions (p<0.001).
Conclusion
It was confirmed that this program developed by applying DBT-ST was effective in the primary prevention of NSSI for adolescents.
7.The Changes of Coronary Artery Stenosis by Sequential Coronary Angiographies.
Je Hyeon SHIN ; Tai Ho RHO ; Seung Hyeon KO ; Hyun Seung LEE ; Jong Goo YOON ; Hee Yeol KIM ; Jong Jin KIM ; Jae Hyung KIM ; Kyu Bo CHOI ; Soon Jo HONG
Korean Circulation Journal 1996;26(5):962-967
BACKGROUND: QT dispersion(QTd) has been shown to be ventricular electrical instability, especially predictor of ventricular arrythmia and indicator of antiarrythmic effect. It was reported that there was a relationship between acute myocardial infarction and increased QTd in that QTd is dependent of the degree of reperfusion as well as the site and size of infarction. In this study, we intended to verify a significant association between myocardial ischemia and QTd by comparing the changes in QTd with or without chest pain in patients with unstable angina who had proven myocardial ischemic changes. METHOD: We studied 20 patients (12 men and 8 women : mean age, 58+/-3.4 years) with unstable angina who had proven myocardial ischemic changes and perfusion defect by 24 hour Holter monitoring, Treadmill test, or coronary angiography. Each case was measured QTd during chest patin and resting state 24 hours after chest pain. All standard 12-lead ECGs were recorded at a speed of 25 mm/sec and examined retrospectively by one observer. QTd corrected for heart rate (QTcd) was calculated by Bazett's formula. The difference of QTd was assessed by comparing by paired t-test. RESULTS: The mean values of QTd were 117.9+/-49.9 msec and 69.7+/-30.2 msec with existence and the absence of chest pain. There was significant increment of QTd when the paients with unstable angina had chest pain(p<0.01). QTcd also significantly increased with the mean value of 119.7+/-57.1 and 74.9+/-36.6 msec (p=0.015). CONCLUSIONS: The results of this study clarified the change of QTd with myocardial ischemia. We expect QTd using a single, noninvasive method to indicate that the chest pain is induced by myocardial ischemic changes. For the furture, it may be possible to study as to the significance of QTd as a predictor of cardiovascular accidents in patients with unstable angina by measuring the serial QTd.
Angina, Unstable
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Arrhythmias, Cardiac
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Chest Pain
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Coronary Angiography*
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Coronary Stenosis*
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Coronary Vessels*
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Electrocardiography
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Electrocardiography, Ambulatory
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Exercise Test
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Female
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Heart Rate
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Humans
;
Infarction
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Male
;
Myocardial Infarction
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Myocardial Ischemia
;
Perfusion
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Reperfusion
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Retrospective Studies
;
Thorax
8.Infection status of pond smelts, Hypomesus olidus, and other freshwater fishes with trematode metacercariae in 6 large lakes.
Shin Hyeong CHO ; Woon Mok SOHN ; Sung Shik SHIN ; Hyeon Je SONG ; Taek Gyun CHOI ; Chang Mi OH ; Yoon KONG ; Tong Soo KIM
The Korean Journal of Parasitology 2006;44(3):243-246
In order to determine the current infection status of pond smelts, Hypomesus olidus, and other freshwater fishes with trematode metacercariae, a total of 4,861 pond smelts and 18 other freshwater fishes, collected from the Soyang and Uiam Lakes in Gangwon-do, the Unam Lake in Jeollabuk-do, the Jangseong Lake in Jeollanam-do, the Uirim-ji (lake) in Chungcheongbuk-do, and the Andong Lake in Gyeongsangbuk-do, were individually digested with 1% pepsin-HCl and examined under a dissecting microscope. In all pond smelts caught from the 6 lakes, we were unable to detect any known human infectious trematode metacercariae in Korea. However, in other freshwater fishes, such as, Squalidus japonicus coreanus (Unam Lake), and Zacco platypus (Jangseong Lake) and Opsariichthys uncirostris amurensis (Jangseong Lake), metacercariae of human-infecting trematodes, i.e., Clonorchis sinensis and Metagonimus sp. were detected, respectively.
Trematode Infections/*veterinary
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Osmeriformes/*parasitology
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Korea
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Humans
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Fresh Water
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Fish Diseases/*parasitology
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Animals
9.Infections in Bone Marrow Transplant Recipients (1992~1999).
Jeong Ho PARK ; Je Joong LEE ; Ik Joo CHUNG ; Hyeong Joon KIM ; Jong Hee SHIN ; Sei Jong KIM ; Dong Hyeon SHIN
Korean Journal of Infectious Diseases 2001;33(3):165-172
BACKGROUND: Patients receiving bone marrow transplantation (BMT) are highly susceptible to infection. This study aims to analyze the frequencies, types and distributions of the organisms causing infectious complications following BMT. METHODS: We retrospectively analyzed infectious complications of 76 bone marrow transplant patients treated at Chonnam National University Hospital during the period 1992~1999. RESULTS: The patient group consisted of 52 allogeneic and 24 autologous recipients. In the allogeneic recipient group, the majority of the patients were diagnosed with acute myelogenous leukemia (37%) and in the autologous group, non-Hodgkin's lymphoma (58 %). Sixty-five of 76 recipients (85.5%) had a total of 118 infectious complications. Out of the 52 allogeneic and 24 autologous recipients, 87 and 31 infectious complications occurred, respectively. Clinically defined infections were reported in 88 cases, microbiologically defined infections in 20 cases, and unexplained fever in 10 cases. Seventy-two infections occurred within the first 30 days following transplant, 17 cases between days 30 and 100, and 29 cases after the 100th day. Infection of the oral cavity occurred in 25.9% of the subjects, pneumonia in 24.1% and skin and soft tissue infection in 19.4%. Oral mucositis was the most common type of infection within the first 30 days following transplant, pneumonia between days 30 and 100, and skin and soft tissue infection after the 100th day. The causative organisms for bacteremia were gram- positive organisms in four of the cases and gram-negative organisms in six of the cases. Similarly, the causative organisms for pneumonia were cytomegalovirus in 5 cases, Pneumocystis carinii in 1 case, methicillin- resistant Staphylococcus aureus in 1 case, and M. tuberculosis in 2 cases. The most common cause of death was acute respiratory distress syndrome due to pneumonia (11 cases). CONCLUSION: Infection is a major complication in patients undergoing BMT. Infection occurred most commonly within the first 30 days following transplant, with oral mucositis and pneumonia being the most common types of infection. Antimicrobial prophylaxis with improved strategies should be utilized in order to prevent infection during post-BMT immunohematopoietic recovery.
Bacteremia
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Bone Marrow Transplantation
;
Bone Marrow*
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Cause of Death
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Cytomegalovirus
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Fever
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Humans
;
Jeollanam-do
;
Leukemia, Myeloid, Acute
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Lymphoma, Non-Hodgkin
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Mouth
;
Pneumocystis carinii
;
Pneumonia
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Respiratory Distress Syndrome, Adult
;
Retrospective Studies
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Skin
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Soft Tissue Infections
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Staphylococcus aureus
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Stomatitis
;
Transplantation*
;
Tuberculosis
10.Herpes Simplex Virus Type 2 Seroprevalence in Korea: Rapid Increase of HSV-2 Seroprevalence in the 30s in the Southern Part.
Haeng Seop SHIN ; Jeong Joo PARK ; Chaeshin CHU ; Hyeon Je SONG ; Kyung Soon CHO ; Joo Shil LEE ; Sung Soon KIM ; Mee Kyung KEE
Journal of Korean Medical Science 2007;22(6):957-962
To determine the characteristics of seroprevalence of herpes simplex virus type 2 (HSV-2) infection among Korean people, a cross-sectional study was conducted on three groups in 2004. The three groups consisted of the general public who visited public health centers, commercial sex workers (CSWs), and human immunodeficiency virus (HIV)-infected persons. Among the general public, HSV-2 seroprevalence rates for age under the 20s, in the 20s, 30s, 40s and the above 22.6%, 32.7% and 32.3%, respectively, which showed rapid increase of the rate in the 30s (p<0.0001). In case of the above of 19 yr old, women (28.0%) was higher than men (21.7%) (p<0.0001). The rate of CSWs (81.6%) was about 10 times higher than that of general women. In case of HIV-infected men (47.6%), the figure was about 2-3 times higher than that of general men. The low rate in the teens and the 20s proved that it is essential to develop sexually transmitted infections (STIs) prevention programs of education and publicity for them as a precaution measure. This study is the first major study of its kind on HSV-2 and would provide basic data for prevention of STIs including information about target groups subject to vaccination program.
Adult
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Age Factors
;
Aged
;
Antibodies, Viral/*blood
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Female
;
HIV Infections/complications
;
Herpes Genitalis
;
Herpesvirus 2, Human/*immunology
;
Humans
;
Korea/epidemiology
;
Male
;
Middle Aged
;
Seroepidemiologic Studies