1.An Autoplex Treatment in a Hemophilia A Patient with High Titer of Anticoagulant FVIII Antibody.
Korean Journal of Pediatric Hematology-Oncology 1997;4(1):150-154
Hemophilia A is a bleeding disorder resulting from a congenital deficiency of factor VIII. The mainstay of successful hemophilia therapy for either treatment or prevention of acute hemorrage is prompt and sufficient intravenous replacement of factor VIII to hemostatic levels. One of the most serious complications of hemophilia and its therapy is the development of polyclonal antibodies to factor VIII that neutralize factor coagulant activity. APCCs is otherwise known as bypass therapy, products that bypass the requirement for factor VIII for clot formation and moderately effective in controlling bleeding in high inhibitor patients. We experienced a case of hemophilia A with high inhibitor titer in a 13 year-old boy who presented with incarcerated right inguinal hernia and a successful therapeutic effect of APCCs(Autoplex) for controlling post-operative hemorrhages.
Adolescent
;
Antibodies
;
Factor VIII
;
Hemophilia A*
;
Hemorrhage
;
Hernia, Inguinal
;
Humans
;
Male
2.The One-Year Prognostic Value of the Pre-Discharge ECG after the First Acute Myocardial Infarction.
Yeong Ho CHOI ; Suck Koo CHOI ; Won Sang YOO ; Hyun Je LEE
Korean Circulation Journal 1988;18(1):41-47
To assess the prognostic value of the 14 ECG variables obtained from the pre-discharge ECG, 35 patients were followed up for at least one year among the 80 patients of the acute myocardial infarction admitted at Seoul Paik Hospital from Sep. 1983 to Aug. 1986. The following results were obtained. 1) The overall in-hospital mortality rate was 20% and the mortality rate tended to decline year by year. 2) The one-year mortality and morbidity rate of the followed patients was 31.4%. 3) Among the 14 variables obtained from the pre-discharge ECG, T-negativity was the only statistically significant (p<0.05) one to predict the one-year prognosis in the patients after the first myocardial infarction, and we could not derive any meaningful datd from the analysis of the combined effects of the three ECG variables (PTF, ST depression and ST elevation).
Depression
;
Electrocardiography*
;
Hospital Mortality
;
Humans
;
Mortality
;
Myocardial Infarction*
;
Prognosis
;
Seoul
3.MRI-guided Stereotactic Thalamotomy for Cerebral Palsy Patients of Mixed Dyskinesia.
Journal of Korean Neurosurgical Society 1996;25(2):352-359
A few neurosurgical alleviate to alleviate some dyskinesias of cerebral palsy(CP) have been tried. For the spastic and tremor type, the selective posterior rhizotomy and thalamotomy are regarded as treatments of choice but other dyskinesias remains a tough challenge. The authors have performed 48 cases of MRI-guided stereotactic thalamotomy(MGST) in 37 CP patients with mixed dyskinesias from Jun. '92 to Jan. '95 using CRW stereotactic frame and MRI, without any ventriculogram. Depending upon the types of main dyskinesias, the target including ventrolateral nucleus of thalamus or medial nucleus of globus pallidus was(were) selected. Clinical results were verified in terms of preoperative symptoms improvement and patient's satisfaction. In athetoid(42 MGSTs in 32CPs) : excellent 6, good 26, fair 10, and in dystonia(30 MGSTs in 23 CPs): excellent 2, good 18, fair 10, and in spasticity(20 in 17 CPs): excellent 3, good 12, fair 5, and in choreoor choreoathetoid(7 in 6 CPs) : good 5, fair 2. Recurrence of symptoms after operation was noted in 6 cases(12.5%). Postoperative morbidity including motor weakness, speech disturbance, swallowing difficulty, and sensory abnormality were transiently noted in 9 cases(18.8%). It is the authors observation that MGST seems to be one of the beneficial procedures for relieving symptoms of CP with mixed dyskinesias.
Cerebral Palsy*
;
Deglutition
;
Dyskinesias*
;
Globus Pallidus
;
Humans
;
Magnetic Resonance Imaging
;
Muscle Spasticity
;
Recurrence
;
Rhizotomy
;
Thalamus
;
Tremor
4.Production of the monoclonal antibody and the genomic library of helicobacter pylori.
Kwang Ho RHEE ; Woo Kon LEE ; Seung Chul BAIK ; Myung Je CHO ; Hyu Jin CHOI
Journal of the Korean Society for Microbiology 1991;26(4):305-316
No abstract available.
Genomic Library*
;
Helicobacter pylori*
;
Helicobacter*
5.Intrapulmonary synovial sarcoma: A case report.
Jae Seung SHIN ; Jae Joon HWANG ; Young Ho CHOI ; Hark Je KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(9):726-729
No abstract available.
Sarcoma, Synovial*
6.Leiomyoma of the vagina : report of a case.
Sang In CHOI ; Jin Wan PARK ; Tai Young HWANG ; Hyun Ho KIM ; Goo Hwa JE
Korean Journal of Obstetrics and Gynecology 1993;36(12):3942-3945
No abstract available.
Leiomyoma*
;
Vagina*
7.Changing pattern of serum leptin concentration in women undergoing clomiphene citrate challenge test or controlled ovarian hyperstimulation.
Doo Seok CHOI ; Jeong Won LEE ; Jin Kyung YOO ; Byung Koo YOON ; Je Ho LEE
Korean Journal of Obstetrics and Gynecology 1999;42(12):2744-2748
OBJECTIVE: To evaluate the changing pattern of serum leptin level and the correlation between estradiol level during the clomiphene citrate challenge test(CCCT) or controlled ovarian hyperstimulation(COH) cycle. METHODS: Twenty-seven women who underwent CCCT and fourteen women who underwent controlled ovarian hyperstimulation were recruited to measure the serum leptin level. After correction of serum concentration with body mass index(BMI), changes of leptin level and correlation with serum estradiol level during CCCT and COH cycle were analyzed. RESULTS: Circulating leptin levels were significantly correlated with BMI at each time point in CCCT cycle(P<0.01). In CCCT cycle, leptin/BMI level was significantly increased at midluteal phase compared to that of menstrual cycle day 3 and 10(p<0.05). In women with regular menstruation, leptin/BMI level at midluteal phase was significantly higher than that of menstrual day 3 and 10, but this difference was not seen in women with irregular menstruation. The leptin/BMI level in COH cycle showed increasing tendency throughout ovarian stimulation. But there was no significant correlation between leptin/BMI and estradiol level in CCCT and COH cycle. CONCLUSION: There is a significant correlation between BMI and circulating leptin level. Midluteal leptin level is significantly higher than that of follicular phase in CCCT cycle, and there is an increasing tendency in leptin level after ovarian stimulation in CCCT and COH cycle without statistical significance. These findings suggest that circulating estradiol concentration has no major influence on circulating leptin level.
Clomiphene*
;
Estradiol
;
Female
;
Follicular Phase
;
Humans
;
Leptin*
;
Menstrual Cycle
;
Menstruation
;
Ovulation Induction
8.A surgical correction of the isolated craniosynostosis.
Eul Je CHO ; Byung Yoon PARK ; Young Ho LEE ; Joong Uhn CHOI
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(5):761-771
No abstract available.
Craniosynostoses*
9.A study on the medical care expenditure of the uterine cervix carcinoma by clinical stage and treatment modality.
Hyo Ki MIN ; Doo Chae JUNG ; Soo Yong CHOI ; Je Ho LEE ; Jae Kyu LIM
Korean Journal of Epidemiology 1992;14(2):160-174
No abstract available.
Cervix Uteri*
;
Female
;
Health Expenditures*
10.Significance of Nephrectomy in Renal Tuberculosis Patients with Negative Urine (AFB) Culture and Asymptomatic Nonfunctioning Kidney.
Do Ri KIM ; Ho Cheol CHOI ; Sung Hyup CHOI
Korean Journal of Urology 2002;43(9):723-726
PURPOSE: The aim of this study was to evaluate the surgical treatment of incidentally detected, asymptomatic, unilateral nonfunctioning tuberculous kidney. MATERIALS AND METHODS: Thirty-three patients with incidentally detected, asymptomatic, unilateral nonfunctioning kidney, negative urine AFB culture and radiologic diagnosis of renal tuberculosis were reviewed. They were divided into three groups: surgical, medical, and observation groups. Twelve patients in the surgical group were nephrectomized at initial diagnosis. Eleven patients in the medical group received anti-tuberculous medication with isoniazid, rifampin, and pyrazinamide for 4 months. Ten patients in the observation group remained under observation. RESULTS: There was no evidence of decreased renal function or recurrence of renal tuberculosis in the surgical and medical groups. Pathologic confirmation of renal tuberculosis was obtained in all nephrectomy patients. The follow-up loss rate of the surgical group (7.7%) was lower than that of the other groups (p<0.05). CONCLUSIONS: Nephrectomy is more acceptable than either medicine or observation. (1) Because preoperative chemotherapy was not justified in the case of negative urine AFB culture, pathologic confirmation was necessary. (2) Nephrectomy associated morbidity was quite low. (3) The follow-up loss rate of the surgical group was lower than that of the other groups. Short course anti-tuberculous medication should be administered after nephrectomy.
Diagnosis
;
Drug Therapy
;
Follow-Up Studies
;
Humans
;
Isoniazid
;
Kidney*
;
Nephrectomy*
;
Pyrazinamide
;
Recurrence
;
Rifampin
;
Tuberculosis, Renal*