1.Enhancement of Immunogenicity of the Inefficient Antigen Through DNA Vaccine-based Epitope Modification.
Soong Hwa JANG ; Mi Jin KIM ; Yong Suk JANG
Korean Journal of Immunology 2000;22(3):111-116
No abstract available.
DNA*
2.Esophagus, Stomach & Intestine; A Case of Esophageal Candidiasis Presenting Recurrent Abdominal Pain in an Immunocompetent Child.
Korean Journal of Gastrointestinal Endoscopy 1997;17(1):55-58
Candida albicans is the most common cause of infectious esophagitis and usually is an opportunistic infection in immunocompromised patients. Dysphagia and odynophagia are the usual presenting complaints and, importantly, oral lesions are absent in 50 percent of patients. The role of gastrointestinal endoscopy in diagnosing fungal infections of the esophagus is primary. It is the most definitive and often the only method of detecting esophageal candidiasis. Accurate endoscopic diagnosis by biopsy or brushing leads to the initiation nf effective therapy. We have experienced a case of esophageal candidiasis in an 11-year-old girl who was immunologically normal and whose main symptoms were epigastric abdominal pain and nausea for 4 months. The endoscopic and pathologic findings of esophageal candidiasis were presented.
Abdominal Pain*
;
Biopsy
;
Candida albicans
;
Candidiasis*
;
Child*
;
Deglutition Disorders
;
Diagnosis
;
Endoscopy, Gastrointestinal
;
Esophagitis
;
Esophagus*
;
Female
;
Humans
;
Immunocompromised Host
;
Intestines*
;
Nausea
;
Opportunistic Infections
;
Stomach*
3.Abdominal aortic aneurysm in Marfan syndrome
Yong Gwi KIM ; Jang Sang PARK ; Yong Bok KOH
Journal of the Korean Society for Vascular Surgery 1991;7(1):18-22
No abstract available.
Aortic Aneurysm, Abdominal
;
Marfan Syndrome
4.Is the Renal Uptake of 99mTc-DMSA Decreased in Microalbuminuric Diabetic Patient?.
Seong Jang KIM ; In Ju KIM ; Yong Ki KIM
Korean Journal of Nuclear Medicine 1999;33(4):398-404
PURPOSE: Diabetic nephropathy is the most common cause of end stage renal disease and the incidence is progressively increasing. The aim of this study was to investigate the differences of 99mTc-DMSA renal uptake among diabetic patients with normoalbuminuria, microalbuminuria and overt proteinuria, and then to determine the clinical usefulness of 99mTc-DMSA in predicting early diabetic nephropathy. MATERIALS AND METHODS: 99mTc-DMSA scan was performed and a total renal uptake of 99mTc-DMSA was measured in 145 diabetic patients. Patients were divided into 3 groups according to the amount of 24 hour urinary albumin excretion as Group I (normoalbuminuria, 74 cases), Group II (microalbuminuria, 39 cases), and Group III (overt proteinuria, 32 cases). The differences of 99mTc-DMSA renal uptake among the 3 groups and the correlation between the renal uptake of 99mTc-DMSA and other clinical parameters were analyzed. RESULTS: The total renal uptake of 99mTc-DMSA of Group II (40.8+/-11.0%) was significantly lower than that of Group I (54.4+/-6.3%, p<0.001). The uptake of Group III (27.7+/-12.0%) was significantly lower than those of both GroupI and Group II (p<0.001). 99mTc-DMSA total renal uptakes correlated negatively with serum creatinine level (r=-0.629, p<0.001) and positively correlated with creatinine clearance rate (r=0.702, p<0.001). CONCLUSION: 99mTc-DMSA total renal uptake of diabetic patients with microalbuminuria was significantly decreased compared with that of patients of normoalbuminuria. Therefore, 99mTc-DMSA scan can be used as a diagnostic study for early detection of the diabetic nephropathy.
Creatinine
;
Diabetic Nephropathies
;
Humans
;
Incidence
;
Kidney Failure, Chronic
;
Proteinuria
;
Technetium Tc 99m Dimercaptosuccinic Acid*
5.Contents of Lead, Cadmium and Zinc in Bone, Muscle and Fin of Carassius carassius from Middle Stream of Nakdong River, Korea.
Doohie KIM ; Yong Gu KIM ; Bong Ki JANG
Korean Journal of Preventive Medicine 1988;21(2):307-319
In order to determine the contents of lead, cadmium and zinc, the tissues of the crussian carp, Carassius carassius, collected from the middle streams of the Nakdong river were examined. During the dry season from 8 to 15, March, 1987, six loci were selected to sample the fish and river water; five of them were the midstreams of the Nakdong river i.e., the vicinities of the Andong dam, the Nakdong bridge, the Waegwan bridge, Gangjung and Gaepori, the other one was the Kumho river around the Paldal bridge(see Fig.1). The microanalyses of lead and cadmium contents were undertaken by the atomic absorption spectrophotometer(Model IL-551) connected with CTF-IL 655, while that of zinc by the flame method with IL-551 only. The contents of lead and cadmium in water sampled from Gaepori distant from about 30km downward from the junction with the Kumho river were about 1.5 times higher than those from Gangjung distant about 0.5km upward from the junction, and the content of zinc from Gaepori was slightly higher than that from Gangjung. However, the contents of lead and cadmium in water sampled from Gaepori were three fifth of those from the vicinity of Paldal bridge far about 2km upperward from the junction. In the other words, the contents of lead and cadmium in the samples from the vicinity of the Paldal bridge were about 2.5 to 3 times higher than those from the Gangjung and 5 times higher than those from the Andong dam. The contents of the heavy metals in the tissues of Carassius carassius were relatively consistent to those of the aquatic environments were the fish were collected, with higher contents in the tissues of the crussian carp collected from the vicinity of Gaepori and the Paldal bridge which were so much polluted than in those from other loci in upper stream from the junction. And the contents of lead and cadmium in tissues were positively correlated with the age of the fish, however, that zinc was not. The contents of lead in bone of crussian carp from the vicinity of the Paldal bridge in the group of 0-1 year old fish were similar to those of 4-5 years old fish from Gaepori, and higher than those of 3-4 years old fish collected from the upper stream of the junction. It is likely that fishing from Gaepori and the paldal bridge is not recommended, and all the industrial producers have to pay intensive attention to the water pollution due to the sewage disposal.
Absorption
;
Cadmium*
;
Carps*
;
Gyeongsangbuk-do
;
Korea*
;
Metals, Heavy
;
Rivers*
;
Seasons
;
Sewage
;
Water
;
Water Pollution
;
Zinc*
6.Micronucleus test as an index of mutagenicity for workers exposed to chromium.
Hyeong Ryeol YOON ; Jang Rak KIM ; Dae Yong HONG
Korean Journal of Occupational and Environmental Medicine 1993;5(1):45-57
No abstract available.
Chromium*
;
Micronucleus Tests*
7.A Case of Mollaret Meningitis.
Yong Joo KIM ; Soon Sup JANG ; In Joon SEOL
Journal of the Korean Pediatric Society 1988;31(9):1193-1196
No abstract available.
Meningitis*
8.The clinical observation in Kawasaki disease.
Young Jin JANG ; Joong Gon KIM ; Yong Soo YUN
Journal of the Korean Pediatric Society 1992;35(3):330-341
No abstract available.
Mucocutaneous Lymph Node Syndrome*
9.A Hospital-based Case-control Study on the Risk Factors of Cerebrovascular Disease.
Jang Rak KIM ; Dae Yong HONG ; Sung Hak PARK
Korean Journal of Preventive Medicine 1995;28(2):473-486
A hospital-based, matched case-control study was carried out to evaluate the relation ship of various suspected risk factors including snoring and serum level of cholesterol to cerebrovascular disease in Korea. A total of 127 incident cases of cerebrovascular disease(74 cases of cerebral infarction and 53 cases of intracerebral hemorrhage) admitted to the department of neurology in a university hospital from December, 1993 to March, 1995 were compared with 127 matched controls admitted to same hospital in same period. A multivariate analysis suggested that ECG abnormality(left ventricular hypertophy and atrial fibrillation), family history of cerebrovascular disease, fundoscopic abnormality, previous history of transient ischemic attack and hypercholesterolemia were risk factors of cerebrovascular disease. ECG abnormality, fundoscopic abnormality, smoking and hypercholesterolemia were also suggested as risk factors of cerebral infarction.
Case-Control Studies*
;
Cerebral Infarction
;
Cholesterol
;
Electrocardiography
;
Humans
;
Hypercholesterolemia
;
Ischemic Attack, Transient
;
Korea
;
Multivariate Analysis
;
Neurology
;
Risk Factors*
;
Ships
;
Smoke
;
Smoking
;
Snoring
10.Successful hybrid operation of an acute mobile thrombus in the abdominal aorta induced by chemotherapy.
Woo Chul KIM ; Kee Chun HONG ; Jang Yong KIM ; Soon Gu CHO ; Yong Sun JEON
Journal of the Korean Surgical Society 2011;81(Suppl 1):S78-S81
Acute mobile thrombus of the abdominal aorta after chemotherapy is a very unusual finding, which can be a potential source of arterial embolism. We report here on a case of an acute mobile aortic thrombus with renal infarction. We successfully treated the patient with hybrid operation-open surgical and endovascular approach. Our case shows that hybrid treatment using wire-directed balloon catheter thrombectomy is a feasible, minimally-invasive treatment for a mobile aortic thrombus.
Angioplasty
;
Aorta
;
Aorta, Abdominal
;
Catheters
;
Chimera
;
Embolism
;
Humans
;
Infarction
;
Thrombectomy
;
Thrombosis