This study was made to investigate the effect of adenoidectomy on dentofacial skeleton in naso-respiratory dysfunction children. The clinical material compromised the 24 children in a previous study who had naso-respiratory dysfunction and 24 children who were the nasal breathing with normal occlusion. The cephalograms were taken at the initial examination and 1 year later for the control group and experimental group the paired sample statistical analysis was performed. The results were as follows. 1. In cranial base variable, difference between two groups were not statistically significant. 2. In craniofacial variables, experimental group showed brachyfacial pattern but control groups didn't show significant growth pattern. 3. In maxillary variables, experimental group showed flattening the plane. 4. In mandibular variables, experimental group showed the decrease of mandibular plane angle and gonial angle. 5. In facial height variables, experimental group showed horizontal growth rotation.
Adenoidectomy* ; Adenoids ; Child* ; Humans ; Respiration ; Skeleton* ; Skull Base

The traumatic retinopathy of Purtcher, traumatic liporrhagia retinae or traumatic retinal angiopathy, which has long been known to follow accidents, which is supposed to be caused by fat embolism due to particularly those involving extensive crushing or fractures in various part of the body, not from direct injuries of the eye. Ophthalmological reports on such conditions are rare. Recently we experienced a case of Purtscher's disease in which 52 year old male patient was first admitted in orthopedic department with anterior iliac crest bone fracture, left 6th-7th ribs fractures and pneumo thorax by being pinned down under about 2 tons weights at a casting factory, Accordingly, we report here a case of traumatic retinopathy of Purtcher with literature.
Embolism, Fat ; Fractures, Bone ; Humans ; Male ; Middle Aged ; Orthopedics ; Retina ; Retinaldehyde ; Ribs ; Thorax ; Weights and Measures

Osteosarcoma in soft tissue is rare and its prognosis is very grave. Comparing with the osteosarcoma of bone, the former is rarer in incidence, poorer in prognosis and found in older patients. Trauma, irradiation or myositis ossificans are considered to be the causes of this tumor. The radical and meticulous surgery is indispensable to eradicate the focus, but there is not infrequent local recurrence and metastasis. We experienced a case of osteosarcoma in the calf muscle, which seemed apparently to have developed from the myositis ossificans without any definite trauma history. In this case the tumor focus was controlled with surgery and radiation therapy but it was found metastasized to the lung and scalp afterwards.
Humans ; Incidence ; Lung ; Myositis Ossificans ; Neoplasm Metastasis ; Osteosarcoma ; Prognosis ; Recurrence ; Scalp

No abstract available.
Maxillary Sinus* ; Orbit* ; Orbital Fractures*

No abstract available.
Hemophilia A* ; Humans

Since the classical description of pyoderma gangrenosum by O'Leary, Brunsting and Goecgerman in 1930, a considerable nurnber of reports of this clinical entity has appeared. Pyoderma gangrenosum is a painful, ulcerative disease of the skin. The ulcers are highly characteristic in clinical feature as necrotic pus covered lesions having purple colored and elevated border with red halo. Frequently, the ulcers heal with a cribriform type of scar. Its pathogenesis is not understood clearly. We present a case of pyoderma gangrenosum deveIoped on the leg in a 11-year old boy occurring with rectal poIyp, the association of whicb is very rare in world wide. And this case has the evidence of cell mediated immunity impairment characterized by no response to mumps antigen and purified protein derivatives, and not to be activively sensitized by DNCB.
Child ; Cicatrix ; Dinitrochlorobenzene ; Humans ; Immunity, Cellular ; Leg ; Male ; Mumps ; Polyps* ; Pyoderma Gangrenosum* ; Pyoderma* ; Skin ; Suppuration ; Ulcer

OBJECTIVE: Lithium inhibits the action of inositol monophosphatase(IMPase) in phosphoinositide(PI) signal transduction system at therapeutically relevant concentration. The depletion of inositol by lithium itself cannt explain the lithium's therapeutic effect. However, attention has focused on the abnormality of PI signal transduction system as the pathophysiology of bipolar affective disorder(BPD). We investigated whether IMPase mRNA levels of lymphocytes would be different between BPD patients(n=16) and age, sex-matched normal controls(n=16). We also investigated the change of IMPase mRNA level by lithium during 4 weeks to probe the possibility that IMPase mRNA levels could predict the therapeutic response to lithium and clinical course. METHOD: Relative IMPase mRNA levels in lymphocyte were quantified by reverse transcriptase(RT)-PCR in sixteen drug-free BPD patients and sex, age-matched normal controls. The psychopathology of patients were measured using YMRS(Young Mania Rating Scale) and CGI(Clinical Global Impression). RESULTS: There was no significant difference in IMPase mRNA levels between BPD patients and normal controls. And the IMPase mRNA levels were not significantly changed by 4 week treatment with lithium. However, the basal IMPase mRNA levels were negatively correlated with the changes of CGI after 4 weeks. Furthermore, the patients with relatively high basal IMPase mRNA levels showed much more improvement during 4 weeks. CONCLUSIONS: BPD patients and normal controls were not distinguished by lymphocyte IMPase mRNA level. Although we do not support the hypothesis that lymphocyte IMPase activity would be related with the pathogenesis of BPD and the action of lithium, these data raise the possibility that lymphocyte IMPase mRNA levels could function as a predictor of therapeutic response and clinical course of BPD.
5'-Nucleotidase ; Bipolar Disorder ; Humans ; Inositol* ; Lithium* ; Lymphocytes* ; Mood Disorders* ; Psychopathology ; RNA, Messenger* ; Signal Transduction

We studied 283 patients with herpes zoster who visited to the Hangang Sacred Heart Hospital between January, 1982 and December, 1985 about the distribution of age, sex, seasonal incidence, associated diseases, camplications and the effect of systemic prednisolone on post herpetic neuralgia. And we also examined the functional states of involved sensory nerve endings by observing the axon flare response to histamine test. The results were as follows . 1. There was no significant differences in sexual and seasonal distributions. 2. There were low incidences of herpes zoster in age groups of below 20 years and over 70 years than age groups of 20 69 years. 3. Sites of involvement were thoracic(170 cases), cervical(38 cases), trigeminal(35 cases), lumbar(28 cases), sacral(11 cases) and facial(1 case) dermatomes. 4. Associated diseases were diabetes mellitus(7 cases), hypertension(7 cases). pulmonary tuberculosis(6 cases), malignant neoplasms(3 cases) and renal transplantation (1 case). 5. Complications were post herpetic neuralgia(18 cases), keratoconjunctivitis(9 cases), meningoencephalitis(1 case), Ramsay Hunt syndrome(1 case), urinary difficulty(1 case) and generalized varicelliform eruption(1 case). 6. The incidence of post-herpetic neuralgia was reduced by systemic prednisolone therapy in patients over 60 years. 7. There was no decrease of axon flare by histamine test on the affected area in 18 patients with herpes zoster.
Axons ; Heart ; Herpes Zoster* ; Histamine* ; Humans ; Incidence ; Kidney Transplantation ; Neuralgia ; Prednisolone ; Seasons ; Sensory Receptor Cells

Keratosis punctata of palmar creases has been considered an uncommon variant of keratosis punctata, which itself is considered rare condition. Clinically our case, 32-year-old seaman, shows cup-shaped depression of the epidermis of varying size, from 1-3mrn in diameter, limited to the large flexor creases of the palms and digit. The histologic features are hyperkeratotic and slight acanthotic central epidermal depression without parakeratosis and loss of granular layer. A sparse mononuclear infilterate are seen arround the capillaries in the dermal papillas. No relationship to arsenical agents, syphilis, or genetic factors can be ascertained by history.
Adult ; Capillaries ; Depression ; Epidermis ; Humans ; Keratosis* ; Parakeratosis ; Syphilis

We report a case of pityriasis rotunda occurring in a patient with pancreatic adenocarcinoma. The patient was a 64-year old female who had a pancreatic adenocarcinoma. The skin lesions were asymptomatic, multiple, various sized (1 to 15cm in diameter), isolated or confluent and finely scaly light brownish to grayish colored patches on the lower abdomen, back and thigh. Histopathologic findings shawed mild hyperkeratosis, atrophy, loss of granular layer, increased melanin pigments in basal layer of the epidermis and mild perivascular monocytic infiltration in the upper dermis.
Abdomen ; Adenocarcinoma* ; Atrophy ; Dermis ; Epidermis ; Female ; Humans ; Melanins ; Middle Aged ; Pancreas* ; Pityriasis* ; Skin ; Thigh