1.Enhancement of Immunogenicity of the Inefficient Antigen Through DNA Vaccine-based Epitope Modification.
Soong Hwa JANG ; Mi Jin KIM ; Yong Suk JANG
Korean Journal of Immunology 2000;22(3):111-116
No abstract available.
DNA*
2.Erratum: Challenges and Considerations in Sequence Variant Interpretation for Mendelian Disorders
Young Eun KIM ; Chang Seok KI ; Mi Ae JANG
Annals of Laboratory Medicine 2019;39(6):606-606
This erratum is being published to revise the website address of the Korean Reference Genome Database (KRGDB) and correct two typographical errors in the article.
3.Loss of Heterozygosity of p73, APC, and p53 in Hepatoblastoma.
Han Seong KIM ; Young Mi JUNG ; Mi Ran KIM ; Jung Young LEE ; Mi Sook LEE ; Ja June JANG
The Korean Journal of Hepatology 1999;5(1):43-49
BACKGROUND/AIMS: The status of tumor suppression gene can be assessed indirectly by analyzing the loss of heterozygosity. Hepatoblastoma is a malignant liver tumor in childhood. To find the molecular carcinogenetic mechanism of hepatoblastoma, loss of heterozygosity (LOH) of p73, APC and p53 was studied. MATERIALS AND METHODS: Hepatoblastoma tissues from thirty-three cases were collected by lobectomy or tumorectomy. On H- stained sections, normal and tumor cells were microdissected separately and LOH analysis was perfomed using 8 markers: six of p73, one of APC and one of p53. RESULTS: Number of cases showing at least one LOH in six p73 markers was four out of twenty- six (15.4%): each LOH frequencies in D1S160, D1S170, D1S199, D1S228, D1S243 and D1S253 were in order of 7.7%, 0%, 9.1%, 0%, 12.5% and 0%. LOH frequency of APC was 41.7% and that of p53 was 13.3%. CONCLUSION: Low LOH frequency of p73 related markers indicates that p73 gene may not be implicated in carcinogenesis of hepatoblastoma.
Carcinogenesis
;
Hepatoblastoma*
;
Liver
;
Loss of Heterozygosity*
4.Induction of ovulation with follicle-stimulation hormone human menopausal gonadotropin and human chorionic gonadotropin: Correlation of multiple follicular-oocytes development and serum E2 levels as well as fertilizability in ovulatory patients for in vit.
Young Soo KANG ; Mi Young JANG ; Hyang Mi KIM ; Young Soo SON ; Bock Hee WOO
Korean Journal of Obstetrics and Gynecology 1993;36(3):339-352
No abstract available.
Chorionic Gonadotropin*
;
Female
;
Gonadotropins*
;
Humans*
;
Ovulation*
5.Relationship Between Intra-Organizational Communication Satisfaction and Safety Attitude of Nurses.
Kyoung Ja KIM ; Jung Sook HAN ; Mi Sook SEO ; Bong Hee JANG ; Mi Mi PARK ; Hyeoung Mi HAM ; Moon Sook YOO
Journal of Korean Academy of Nursing Administration 2012;18(2):213-221
PURPOSE: Communication in hospitals is one of the major factors in patient safety. So, the purpose of this study was to identify the relationship between intra-organizational communication satisfaction and the safety attitude of nurses in hospitals. METHOD: A descriptive survey design with convenience sampling was used. Data collection was done using a self-report questionnaire answered by 278 nurses from one university hospital located in Kyeoung-gi Province, Korea. RESULT: Intra-organizational communication satisfaction positively correlated with safety attitude (r=.747, p<.01). Among the 6 sub dimensions of safety attitude, perceptions of management (r=.675, p<.01), job satisfaction (r=.640, p<.01) and teamwork climate (r=.600. p<.01) were strongly related to intra-organizational communication satisfaction. Multiple regression analysis was done to identify explanation power of intra-organizational communication satisfaction against safety attitude. The model was significant (F=48.540, p<.01). Intra-organizational communication satisfaction accounted for 60.9% of variance in safety attitude (Adj R2=.609). CONCLUSIONS: The results of this study indicate that higher levels of intra-organizational communication satisfaction promote positive safety attitude in hospital nurses and that communication media quality is an important factor in patient safety attitude. Therefore, developing interventions to revitalize intra-organizational communication level based on communication media quality will help in the construction of positive safety attitude in nurses.
Climate
;
Surveys and Questionnaires
;
Job Satisfaction
;
Patient Safety
6.A Clinical Observation on 24 Hour Holter Monitoring: The Differences between Day and Night Time.
Mi Young JANG ; Jong Hwa KIM ; Jong Man KIM ; Hong Soon LEE ; Hak Choong LEE
Korean Circulation Journal 1984;14(1):125-133
A modern development of ambulatory ECG monitoring gave great advances in the diagnosis and evaluation of various cardiac conditions. Fifteen cases of ischemic heart disease, 11 cases of nonischemic heart disease, 5 cases of noncardiac disease and 9 cases of normal healthy subjects were studied from January 1980 to July 1981 in national Medical Center, with the following results: 1) The heart rate was decreased during night time, with less decreasing tendency in patients with ischemic heart disease. 2) Among 30 cases, including 12 patients with ischemic heart disease, who didn't show arrhythmia on routine 12 lead ECG, 12 cases, including 6 patients with ischemic heart disease, showed arrhythmia on Holter monitoring. 3) Among 5 cases with ischemic heart disease who showed premature ventricular contraction on day time monitoring, 2 cases didn't show premature ventricular contraction on nigh time monitoring. 4) The S-T segment and T wave were changed during night time in 2 cases with ischemic heart disease and in 2 normal subjects. From these results, we could assert that Holter monioring or ambulatory ECG tracing would be a good method for diagnosis and evaluation of ischemic heart disease, and other cardiac conditions. Several another studies with this equipment have to be performed and would give more distinctive outcomes.
Arrhythmias, Cardiac
;
Diagnosis
;
Electrocardiography
;
Electrocardiography, Ambulatory*
;
Heart Diseases
;
Heart Rate
;
Humans
;
Myocardial Ischemia
;
Ventricular Premature Complexes
7.Mycotic Aneurysm of Abdominal Aorta Causing the Right Renal Arterial Stenosis: Case Report.
Journal of the Korean Radiological Society 2003;49(4):271-273
Mycotic aneurysm of the abdominal aorta is a rare disease. Despite intensive antibiotic therapy, rupture leads to a high mortality rate, so early diagnosis and treatment is very important. Rupture is the most common complication of abdominal aortic aneurysm, while renal artery stenosis is very rare. We report the radiologic findings of mycotic aneurysm of the suprarenal abdominal aorta leading to right renal artery stenosis induced by mass effect and renovascular hypertension.
Aneurysm, Infected*
;
Aorta, Abdominal*
;
Aortic Aneurysm, Abdominal
;
Constriction, Pathologic*
;
Early Diagnosis
;
Hypertension, Renovascular
;
Mortality
;
Rare Diseases
;
Renal Artery Obstruction
;
Rupture
8.Torsion and ruptured dysgerminoma of ovary in pregnancy.
Chang Kyo LIM ; Hye Young KIM ; Jang Yeoun KWON ; Dae Hyun KIM ; Mi Yeoun CHO
Korean Journal of Obstetrics and Gynecology 1992;35(2):292-296
No abstract available.
Dysgerminoma*
;
Female
;
Ovary*
;
Pregnancy*
9.The Effect of Sensory Stimulation on Mother-Infant Interaction in Premature Infants.
Mi Ye KIM ; Sun Hee KIM ; Gun Ja JANG
Korean Journal of Child Health Nursing 2004;10(2):180-187
PURPOSE: This study was designed to investigate effect of sensory stimulation on the mother-infant interaction in premature infants. METHOD: The subjects of this study consisted of 36 pairs of premature infants and their mothers from NICU of one university hospital located in Taegu, 18 pairs for intervention group and 18 pairs for control group. The data were collected from May, 1999 to October, 2000. For the intervention group Field's sensory stimulation(tactile and kinesthetic stimulation) was applied 2 times a day for 10 days(10:00-11:00 in the morning and 7:00-8:00 in the afternoon by researcher and mother). To determine mother and infant interaction during feeding, tool developed by Kim Mi-Ye(1999) was used. Collected data were analyzed with SAS program using chi-square test and t-test. RESULT: Significant differences were found in mother-infant interaction between two groups(t=-5.38, p=.00). It indicates that sensory stimulation was effective in improving mother-infant interaction. In the aspects of the quality of mother-infant interaction, sensory stimulation was most effective in improving sensitivity to mother and infant's synchronic behaviors(t=-5.43. p=.00) and followed by growth fostering(t=-5.07, p=.00), sensitivity to infant's cues(t=-4.53, p=.00), clarity of infant's cues(t=-3.03, p=.00) and responsiveness to the mother's behaviors(t=-2.14, p= 0.04). CONCLUSION: Based on the result of this study, it is suggested that maternally administered sensory stimulation should be applied clinical practice to improve interaction of premature infants and their mothers.
Daegu
;
Humans
;
Infant
;
Infant, Newborn
;
Infant, Premature*
;
Mother-Child Relations*
;
Mothers
;
Child Health
10.Determinants of Nutrition Service Utilization in Health Centers.
Youngok KIM ; Kyunghee JANG ; Mi Kyung KIM
Korean Journal of Community Nutrition 2001;6(1):91-96
The purpose of this study was to identify the determinants of nutrition service utilization in health centers. Utilization of nutrition services for chronic discase were also investigated. Interview survey using questionnaire was conducted to collect the data required for analysis. The study subjects were 300 residents over 40 years of age, and 15 health workers representing health center service personnel in Kypnggi province. A wilcoxon 2-sample test and Kruskal-Wallis test were used to compare the distribution of health centers by health center characteristics and nutrition services. A chi-square test was used to test the association between service utilization and personal variables of the population. A multiple logistic regression analysis was used to measure the relative importance between the variables on service utilization. The results showed that only 10.0% of the study subjects used nutrition services provided by the health centers. Pilot project implementation and location of health centers, as well as educational level of the residents were significant factors influencing the utilization of the nutrition services provided by the health centers. Among the variables, pilot project implementation was the most important factor that influenced the nutrition service utilization in health centers.
Chronic Disease
;
Chymopapain
;
Humans
;
Logistic Models
;
Pilot Projects
;
Surveys and Questionnaires