1.A Study on the Solar UVA and UVB Doses at Kongju.
Korean Journal of Dermatology 1987;25(1):16-24
An appreciation of daily and annual changes of ultraviolet radiation is important in order to optimize the conditions for climatic therapy of skin diseases or in order to minimize the harmful effects of the sun. Ultraviolet A(355nm) and ultrviolet B(290nm) doses were measured at Kongju from April to September, 1985, on two different weather conditions-clear and relatively clear. The followings were the summary of the findings. 1. On clear weather, UVA dose was peak at noon of the day and in June of the year. 2. On relatively clear weather, UVA dose was peak at 2 p.m. of the day and in July of the year. 3. UVB dose was peak at noon of July regardless of weather conditions. 4. In relatively clear weather the UVA and UVB doses decreased from those of clear weather by 29%, and 36% respectively. 5, The relative difference between the doses of UVA and UVB depended on the degree of solar zenith angle. The greater the solar zenith angle, the greater the difference. 6. In order to treat a patient with solar UVA radiation, therefore, it is suggested to have the patient expose himself to the sun around 10 a, m. and 3 p.m. to minimize the harmful effects of solar UVB. However, when one wants to treat with solar UVB radiation, it would be better to expose to the sun around noon.
Chungcheongnam-do*
;
Humans
;
Skin Diseases
;
Solar System
;
Weather
2.A case of acral persisitent papula mucinosis.
Jeung Hoon LEE ; Jang Kyu PARK
Korean Journal of Dermatology 1993;31(2):232-235
We report a case of acral persistent papular mucinosis in a 5 year-old female with multiple papules on both dorsa of the hands, wrists and forearms. Examination of a biopsy specimen showed a domeshaped lesion in the dermis composed of spindle-shaped fibrobla,sts and widely spaced collagen fibers. These spaces were filled with mucinous material, as demonstrated by positive staining with aleian blue at pH 2.5 and pH 0.5.
Biopsy
;
Child, Preschool
;
Collagen
;
Dermis
;
Female
;
Forearm
;
Hand
;
Humans
;
Hydrogen-Ion Concentration
;
Mucinoses*
;
Mucins
;
Scleromyxedema
;
Wrist
3.A Study on the Minimal Phototoxic Dose (MPD).
Yoon Seong KIM ; Jang Kyu PARK
Korean Journal of Dermatology 1986;24(1):16-21
In order to measure the MPD with 8-methoxypsoralen, we selected 49 Korean healthy male vlunteers without phototoxic or photosensitive dermatoses. They were divided to 3 groups (Immediate; group 1, 1 hour; group 2, 2 hours', group 3) according to the waiting time, intervals of application of photosensitizer a,nd UVA:irradiation. The reaults were summarized as follows: 1. MPDs of group 1 had no clinical significance. 2, MPDs of group 2 were more than those of group '3 independently of application methods of photosensitizer. 3. In the cases of topical application of 8-MOP, MPDs of group 3 according to reading interval (24 hours, 48 hours and 72 hours after UVA irradiation) were 3.4+/-2.9 J/cm2, 1.9+/-l.5 J/cm' and l. 7+1, 2/cm, respectively. 4 In the cases of oral administration of 8-MOP, MPDs of group 3 according to reading; interval as topical application of 8-MOP were 7.1+/-2.3 J/cm, 4.4+/-1.1 J/ cm2 and 4.2+/-l.2 J/cm2, respectively. 5 MPL)s accarding to the skin types as follows; (waiting time; 2 hours, read- ing interval; 48 hours) a. In the case of topical application of 8-MOP, MPDs of the skin type ]II, 1V and V were 0.9+/-0.5 J/cm2, 1.8+/-1.1 J/cm2 and 3.0+/-l.3 J/cm2 respectively. b. In the case of oral administration of 8-MOP, MPDs of skin type g, W and were 3.5+/-1.1 J/cm2, 4.7+/-1.3 J/cm2 and 6.9+/-l.8 J/cm2, respectively.
Administration, Oral
;
Humans
;
Male
;
Methoxsalen
;
Skin
;
Skin Diseases
4.A Mycologic Study from the Fourth Toe Web of the High School Studyent.
Ja Kyeong KOO ; Jeung Hoon LEE ; Jang Kyu PARK
Korean Journal of Dermatology 1988;26(5):666-670
Exogenoue exposurea to pathogenic fungi have been suggested as causes of acute atta.eks of tinea pedis. Psthogenic fungi is rarely present on the skin aurfaces without cauaing definite and characteristic reactions. However, it was suspected by eome observers that pathogenic fungi might be more or liesa normal inhabitant of the human skin. Alterations in host susceptibility and loss, of local immunity are more to blame than new exposure to exogenous micro-ganisms. To determine this point, fungal culture was done from the fourth toe web of 824 high school students. The results of the study were summarized as follows,' l. Among 824 cases, 780 cases(94.7%) had grossly normal appearing toe web and 44 cases(5,3%) were suspected superficial fungal infection. 2. Positive rate of KOH examination was 4.6%(36,'780) in normal toe web and 45.4%(20/44) in dermatophytic lesion. 3, The positive rate of fungal culture from normal and infected toe web are 7.9 %(62/780) a.nd 40.9%(18/44), respectively. In the normal toe web, Trichophyton rubrum(66.1%), T, entagrophytea(include T. interdigitaLe) and Epidermophyton, floccosum(3.2%) were isolated. In the dermatophytic lesion, T. rubrurn(88.8%) and T. me ntagrophytes(11.2% ) w ere isolated. Although toe webs do not present clinical symptoms and signs, pathogenic fungi as a normal inhabitant can be isolated from clinically normal toe webs. Some of these cases, therefore, will develope to tinea pedis in time.
Epidermophyton
;
Fungi
;
Humans
;
Skin
;
Tinea Pedis
;
Toes*
;
Trichophyton
5.A Case of Pityriasis Lichenoides et Varioliformis Acuta Treated with Photochemotherapy.
Yoon Seong KIM ; Hyo Soo HAN ; Jang Kyu PARK
Korean Journal of Dermatology 1986;24(1):107-111
A lg year-old female patient with pityriasis lichenoides et varioliforrnis acuta (PLEVA) was been treated with PUVA, At first, she was treated with tetracycline for 8 weeks with improvement somewhat. But 2 months later, her skin lesions aggravated slowly. So, we tried to treated her with PUVA and then she was cleared completely. The initial dose of UVA was 5 J/cm The UVA dosage increased by 10g of the previous exposure and increased to the maximum dose, 15 J/cm The patient exposed to UVA R times per week. 12 times after the PUVA therapy, the skin lesions begin to improve and completely improved at 21 times of Pl.JVA therapy. She was followed up every week and there was no side effect except hyperpigrnentation till 24 months. The total dose during treatment is 210 J/cm.
Female
;
Humans
;
Photochemotherapy*
;
Pityriasis Lichenoides*
;
Pityriasis*
;
PUVA Therapy
;
Skin
;
Tetracycline
6.Research of Malpractice in Skin Diseases.
Gi Bum SHUR ; Jeung Hoon LEE ; Jang Kyu PARK
Korean Journal of Dermatology 1988;26(3):314-319
Among the patients visting Department of Dermatology, Chungman National University, 58 cases had various side effects due to the malpractice of skin disorders. We analysed these 58 cases and the results can be summerized as follows ; 1. 37 cases(64%) were in the second and third decades and 11 cases(19%) were under 19 years-old. 2. Drug medication from pharmacy was the most common(79%), and then local clinics(12%), herb clinics(9%) in decreasing orders. 3. In the route of administration, oral ingestion(38%) was the most common, and 47 cases (81%) were medicated with adrenocorticoids. 4. In motivation to the visit, 31 cases(53%)were by advice, 15 cases by advertizement and 12 cases (21%) by themselves. 5. Acne and psoriasis were about a half of pre-existing skin diseases. 6. Side effects due to malpractice may be divided into 5 items : systemic side effects due to adrenocorticoids (59%), aggravation of pre-existing skin diseases (22%), topical side effects due to adrenocorticoids (10%), chemical irritation and burn (7%), and mercury intoxication (2%) in decreasing orders.
Acne Vulgaris
;
Administration, Oral
;
Burns
;
Dermatology
;
Humans
;
Malpractice*
;
Motivation
;
Pharmacy
;
Psoriasis
;
Skin Diseases*
;
Skin*
;
Young Adult
7.Histologic Changes of Normal Human Skin in Organ Culture.
Jeong Hyon BAEK ; Yeul Hoon SUNG ; Jeung Hoon LEE ; Jang Kyu PARK ; Jeong Kyu PARK
Korean Journal of Dermatology 1990;28(2):130-135
Since adult human skin can be grown in chernically defined medium without serum, the skin organ culture has gained a great interest as a method for studies concerning skin biology, pharmacology and toxicology. however, serum supplementation has extensively been used to improve the viahility of tissue culture. This study was undertaken to evaluate the effect of serum on the histologic changes ohserved during the organ culture of the normal human skin. The general architecture of the skin was well maintained for 6 days with or without seru. After then, fetal calf serum or autologous human serum was found to enhance the viability of the epidermis. A confluent layer of necrotic spinous ceils was ovserved earlier and more widespread without serum. The addition of serum had an impressive effect on epibolization. In the absenee of serum, the formation of the epibolus was not only minimal, but also, susceptible to degeneration, and no epibolus remained at 10 days rif incubation. No difference can be found between fetal calf serm and autologous human serum in the formation of the epibolus. There was no favorable effect of serum on the formation of new stratum corneum. The thickness of new straturn corneum increased in parallel with the number of parakeratatic cells, increasing most rapidly between 6 and 8 days of incubation. Parakeratosis was more prominent in the presence of serurn.
Adult
;
Biology
;
Epidermis
;
Humans*
;
Organ Culture Techniques*
;
Parakeratosis
;
Pharmacology
;
Selective Estrogen Receptor Modulators
;
Skin*
;
Toxicology
8.A Case of Sturge-Weber Syndrome.
Jun Taek PARK ; Geom Hyun JANG ; Jae Kyu LEE ; Kyu Eun LEE ; Jung Hyup OH
Journal of the Korean Pediatric Society 1983;26(8):823-828
No abstract available.
Sturge-Weber Syndrome*
9.Three cases of benign symmetric lipomatosis.
Yeol Oh SUNG ; Jeung Hoon LEE ; Kyung Hoon KIM ; Mu Kyu SUH ; Jang Kyu PARK
Korean Journal of Dermatology 1993;31(5):800-805
Benign symmetric lipomat,osis is a rare disease of undetermined cause characterized by symmetric deposits of adipose tissue o:n the neck, upper trunk and abdomen. We report three cases of kienign symmetric lipomatosis, one of which is associated with alcoholic liver disease and the patient complained of a diffieulties in neck motion, All of them are about sixty year old men with history of frequent alcohol consumption. In histopathologic findings, the reticular dermis was completcly replaced by mature fat cells and there was a slight increase in vascular and fibrous elements.
Abdomen
;
Adipocytes
;
Adipose Tissue
;
Alcohol Drinking
;
Dermis
;
Humans
;
Lipomatosis*
;
Liver Diseases, Alcoholic
;
Male
;
Neck
;
Rare Diseases
10.Changes of segmental left ventricular wall motion after coronary artery bypass graft surgery ; two-dimensional echocardiographic study.
Soo Yeon WON ; Il Mun JEON ; Myoung Seon PARK ; Myoung Kyu JANG ; Jae Kyu RYU ; Jin Won JEONG ; Yang Kyu PARK ; Ock Kyu PARK ; Jong Bum CHOI
Korean Journal of Medicine 1993;45(6):770-780
No abstract available.
Coronary Artery Bypass*
;
Coronary Vessels*
;
Echocardiography*