No abstract available.
Glycopyrrolate* ; Salivary Glands* ; Scopolamine Hydrobromide*

BACKGROUND AND OBJECTIVES: Dentigerous cysts arise from the reduced enamel epithelium and expand into the surrounding bone. They grow unnoticed to such extensive sizes as to occupy a considerable portion of the maxillary sinus. This study was designed to clarify the clinical, radiological and histopathological features of ten cases of the dentigerous cyst involving the maxillary sinus. MATERIALS AND METHODS: Medical records of ten patients, who were diagnosed with dentigerous cyst, were analyzed from June 1990 to May 2000 retrospectively. RESULTS: The greatest incidence of dentigerous cyst occurred between the ages of 10 and 30 years old (average age 29.6 years). Facial swelling and pain were the most common com-plaints, followed by oro-antral fistula, headache and facial numbness. CT scan of paranasal sinuses showed a slightly nonhomogeneous soft tissue density surrounded by an incomplete bony wall which occupied partially antral space. In the middle of the cyst, the isolated high density of unerupted tooth was seen. In the lining epithelium, the stratified squamous epitheliums were the most frequent. Six patients underwent cyst removal via Caldwell-Luc approach and four patients underwent cyst removal via intraoral approach. The postoperative course has been gone well without recurrence. CONCLUSIONS: The differential diagnosis and early detection of the dentigerous cyst in involving maxillary sinus are important. Rhinologist should be aware of this disease entity when encountered with patients presented with unilateral painful swelling of cheek.
Adult ; Cheek ; Dental Enamel ; Dentigerous Cyst* ; Diagnosis, Differential ; Epithelium ; Fistula ; Headache ; Humans ; Hypesthesia ; Incidence ; Maxillary Sinus* ; Medical Records ; Paranasal Sinuses ; Recurrence ; Retrospective Studies ; Tomography, X-Ray Computed ; Tooth, Unerupted

BACKGROUND AND OBJECTIVES: Dentigerous cysts arise from the reduced enamel epithelium and expand into the surrounding bone. They grow unnoticed to such extensive sizes as to occupy a considerable portion of the maxillary sinus. This study was designed to clarify the clinical, radiological and histopathological features of ten cases of the dentigerous cyst involving the maxillary sinus. MATERIALS AND METHODS: Medical records of ten patients, who were diagnosed with dentigerous cyst, were analyzed from June 1990 to May 2000 retrospectively. RESULTS: The greatest incidence of dentigerous cyst occurred between the ages of 10 and 30 years old (average age 29.6 years). Facial swelling and pain were the most common com-plaints, followed by oro-antral fistula, headache and facial numbness. CT scan of paranasal sinuses showed a slightly nonhomogeneous soft tissue density surrounded by an incomplete bony wall which occupied partially antral space. In the middle of the cyst, the isolated high density of unerupted tooth was seen. In the lining epithelium, the stratified squamous epitheliums were the most frequent. Six patients underwent cyst removal via Caldwell-Luc approach and four patients underwent cyst removal via intraoral approach. The postoperative course has been gone well without recurrence. CONCLUSIONS: The differential diagnosis and early detection of the dentigerous cyst in involving maxillary sinus are important. Rhinologist should be aware of this disease entity when encountered with patients presented with unilateral painful swelling of cheek.
Adult ; Cheek ; Dental Enamel ; Dentigerous Cyst* ; Diagnosis, Differential ; Epithelium ; Fistula ; Headache ; Humans ; Hypesthesia ; Incidence ; Maxillary Sinus* ; Medical Records ; Paranasal Sinuses ; Recurrence ; Retrospective Studies ; Tomography, X-Ray Computed ; Tooth, Unerupted

BACKGROUND: The Osteoporosis Health Belief Scale (OHBS) is a 42-item questionnaire designed to assess susceptibility, seriousness, calcium benefits, calcium barriers, exercise benefits, exercise barriers, and health motivation related to osteoporosis. We aimed to evaluate its psychometric properties to enable the provision of educational tips regarding osteoporosis. METHODS: All women who had visited the department of obstetrics and gynecology (OBGYN) and whose bone mineral density was measured from January 2010 to December 2011 were enrolled by interview using the OHBS. We also evaluated the women's general clinical characteristics. RESULTS: One hundred seventy-seven women were enrolled in the present study. In the present study, the barriers to calcium intake subscale had the lowest mean score (15.03+/-3.02), and the Benefit of Exercise subscale had the highest (23.02+/-3.03). The scores for participants in their 20s were significantly higher than scores for those in their 70s on the Benefits of Exercise subscale and Barriers to Exercise subscale (P=0.014 and P=0.022, respectively). CONCLUSIONS: Education for health motivation to prevent osteoporosis is important for young women. Additional systematic education programs are needed for the general population.
Bone Density ; Calcium ; Female ; Gynecology ; Humans ; Motivation ; Obstetrics ; Osteoporosis ; Psychometrics ; Surveys and Questionnaires

Today, almost 20% of female cancers are gynecological in nature. In particular, uterine cervical cancer and endometrial cancer (which have been intensively studied) seriously compromise female health. One of the ezrin-radixin-moesin (ERM) proteins, ezrin, has been associated with cancer in prior studies, including the two cancers mentioned above. Ezrin expression increases, as does the expression of other factors, in uterine cervical cancer; ezrin may promote cancer development by influencing the actions of the other factors. Also, an increase in ezrin level contributes to the development of diseases such as endometrial cancer.
Cervical Intraepithelial Neoplasia ; Endometrial Neoplasms ; Female ; Humans ; Uterine Cervical Neoplasms ; Uterine Neoplasms*

No abstract available.
Alkaline Phosphatase ; Cell Adhesion ; Fibronectins* ; Humans* ; Osteoblasts

BACKGROUND AND OBJECTIVES: The Korean phonetically balanced (PB) word list (Ham's Korean PB Word List) is currently the most commonly used word list for speech discrimination test. The aim of this study was to investigate the frequency characteristics of the Ham's Korean PB word list and to compare frequency characteristics of the Ham's Korean PB word list with that of the 21st Century Sejong words, which represent characteristics of the contemporary spoken Korean language. SUBJECTS AND METHOD: The 300 syllables most commonly used were collected from the words in 21st Century Sejong project. The 21st Century Sejong words were weighted according to the frequency of usage. The 21st Century Sejong words and words from the Ham's Korean PB word list were analyzed using an acoustic analysis program that has the MATLAB function. RESULTS: Syllables with frequencies above 2,000 Hz comprise 34% of the 21st Century Sejong words and 16% of the Ham's Korean PB word list. The Ham's Korean PB word list does not represent the high frequency characteristics of the contemporary spoken Korean language. The 21st Century Sejong words have more 'eu', 'i' and open syllables than the Ham's Korean PB word list. CONCLUSION: The Ham's Korean PB word list does not reflect the high frequency characteristics of the contemporary spoken Korean language included in the 21st Century Sejong words. Therefore, a new PB word list that incorporates a greater number of syllables with high frequency characteristics is required.
Acoustics* ; Audiometry, Speech ; Speech Acoustics ; Speech Discrimination Tests

PURPOSE: Several factors including dialysis adequacy are now known to be related to clinical outcomes of CAPD patients. In our study, the long term effects of dialysis adequacy, residual renal function, nutritional indices, and peritoneal membrane transport characteristics on the outcomes of CAPD patients were evaluated. METHODS: Prevalent or incident 127 patients were enrolled from February 1998 to January 1999. Follow-up was terminated in January 2003. In 41 patients, parameters of adequacy were reevaluated, and the effects of parameter change over time on patient outcomes were analyzed. RESULTS: Seventy-two were male. Twenty-nine (23%) were diabetic. Mean age was 47+/-2.9 years, and the mean follow up period was 45+/-.8 months. The baseline serum albumin was 3.7+/-.5 g/dL. nPCR was 0.8+/-.2 g/kg/d, and %lean body mass was 68.4+/-4.3. Kt/V was 2.0+/-.7, and Ccr was 64.5+/-8.8 L/wk/1.73 m2. The estimated GFR was 1.1+/-.3 mL/min. The multivariated analysis demonstrated that diabetes, serum albumin, and the patent residual renal function were independent factors of the patient and technique survival. Membrane transport characteristic was a predictor of technique survival. Among patients for whom the parameters of adequacy were reevaluated, a more rapid decrease of serum albumin and a more rapid increase of membrane transport characteristics were associated with increased risk of either death or technique failure. CONCIUSION: Nutritional indices and presence of residual renal function have a significant impact on the clinical outcome. The decrease of serum albumin and the increase of membrane transport characteristic have negative impacts on patient and technique survival.
Dialysis* ; Follow-Up Studies ; Humans ; Male ; Membranes ; Nutrition Assessment* ; Peritoneal Dialysis, Continuous Ambulatory* ; Serum Albumin

PURPOSE: Several factors including dialysis adequacy are now known to be related to clinical outcomes of CAPD patients. In our study, the long term effects of dialysis adequacy, residual renal function, nutritional indices, and peritoneal membrane transport characteristics on the outcomes of CAPD patients were evaluated. METHODS: Prevalent or incident 127 patients were enrolled from February 1998 to January 1999. Follow-up was terminated in January 2003. In 41 patients, parameters of adequacy were reevaluated, and the effects of parameter change over time on patient outcomes were analyzed. RESULTS: Seventy-two were male. Twenty-nine (23%) were diabetic. Mean age was 47+/-2.9 years, and the mean follow up period was 45+/-.8 months. The baseline serum albumin was 3.7+/-.5 g/dL. nPCR was 0.8+/-.2 g/kg/d, and %lean body mass was 68.4+/-4.3. Kt/V was 2.0+/-.7, and Ccr was 64.5+/-8.8 L/wk/1.73 m2. The estimated GFR was 1.1+/-.3 mL/min. The multivariated analysis demonstrated that diabetes, serum albumin, and the patent residual renal function were independent factors of the patient and technique survival. Membrane transport characteristic was a predictor of technique survival. Among patients for whom the parameters of adequacy were reevaluated, a more rapid decrease of serum albumin and a more rapid increase of membrane transport characteristics were associated with increased risk of either death or technique failure. CONCIUSION: Nutritional indices and presence of residual renal function have a significant impact on the clinical outcome. The decrease of serum albumin and the increase of membrane transport characteristic have negative impacts on patient and technique survival.
Dialysis* ; Follow-Up Studies ; Humans ; Male ; Membranes ; Nutrition Assessment* ; Peritoneal Dialysis, Continuous Ambulatory* ; Serum Albumin

PURPOSE: We investigated the effects of recombinant 9-10th type III repeat of fibronectin (rhFNIII9-10) on the adhesion, proliferation, and the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells(hMSCs). MATERIALS AND METHODS: Adhesion and blocking assay for hMSCs were performed on the plates which had been coated with 100 microgram/ml rhFNIII9-10 or fibronectin. hMSCs seeded on the precoated plates were cultured in the osteogenic media for 3 weeks. MTS(Dimethylthiazole carboxymethoxyphenyl sulfophenyl tetrazolium compound) assay for the cell number, [Methyl-3H] thymidine incorporation study, alkaline phosphatase activity assay, calcium content assay and RT-PCR for alkaline phosphatase, osteopontin, cbfa-1, and type I collagen were performed during the osteogenic differentiation. RESULTS: hMSCs showed significantly increased adhesion to rhFNIII9-10-coated plates and fibronectin-coated plates. A monoclonal antibody to the integrin alpha 5 beta 1 inhibited adhesion to rhFNIII9-10-coated plates and fibronectin-coated plates in dose-dependent manner. hMSCs seeded on the rhFNIII9-10-coated plates showed increased proliferation during the osteogenic differentiation. However, there was no significant difference in the alkaline phosphatase activity, calcium content and expression levels of mRNAs for alkaline phosphatase, osteopontin, cbfa-1, and type I collagen of hMSCs seeded on the rhFNIII9-10-coated plates. CONCLUSION: rhFNIII9-10 stimulates hMSCs adhesion and increases hMSCs proliferation during the osteogenic differentiation. Although osteogenic differentiation is not promoted, adsorption of rhFNIII9-10 onto appropriate biomaterials can enhance integrin-mediated hMSCs adhesion and proliferation. This biomolecular engineering strategy represents a robust approach to increase biofunctional activity and integrin specificity of hMSCs.
Adsorption ; Alkaline Phosphatase ; Biocompatible Materials ; Bone Marrow ; Calcium ; Cell Count ; Collagen Type I ; Fibronectins* ; Humans* ; Integrin alpha5beta1 ; Mesenchymal Stromal Cells* ; Osteopontin ; RNA, Messenger ; Sensitivity and Specificity ; Thymidine