1.Surgical treatment of the bilateral facial nerve paralysis combined with temporal bone fracture.
Won Sang LEE ; Jang Hoon CHI ; Jeong Hwan LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(3):506-511
No abstract available.
Facial Nerve*
;
Paralysis*
;
Temporal Bone*
2.Histologic findings of temporal bone in idiopathic blue eardrum.
Kee Hyun PARK ; Jang Hoon CHI ; Jung Il CHO ; David J LIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):848-856
No abstract available.
Temporal Bone*
;
Tympanic Membrane*
3.Gold weight implantation for the patient with facial paralysis.
Won Sang LEE ; Jong Hun LEE ; Jang Hoon CHI ; Sang Yeul LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):656-662
No abstract available.
Facial Paralysis*
;
Humans
4.Surgical treatment of facial nerve paralysis via middle cranialfossa approach.
Won Sang LEE ; Jang Hoon CHI ; Hong Joon PARK ; Jae Young KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(1):56-66
No abstract available.
Facial Nerve*
;
Paralysis*
5.The Changes of Na+-K+ ATPase Activity and Ultrastructure of Endolymphatic Secretory Epithelium by Local and Systemic Streptomycin Treatment.
Woon Kyo CHUNG ; Hee Nam KIM ; Won Sang LEE ; Jang Hoon CHI
Korean Journal of Otolaryngology - Head and Neck Surgery 1997;40(11):1616-1631
The endolymphatic secretory epithelium are stria vascularis in cochlear and dark cell in vestibule which are regulated by Na+-K+ ATPase. It is important that we study intracytoplasmic Na+-K+ ATPase for the physiologic research of inner ear. Recently cerium-based method for stain of Na+-K+ ATPase was developed. This study was underkaken to investigate the morphologic changes and Na+-K+ ATPase activity in stria vascularis and vestibular dark cell of mongolian gerbil after systemic intramuscular injection(200mg/kg or 300mg/kg) for 7days or local infiltration of streptomycin through round window. The results are as follows. 1) The strong Na+-K+ ATPase activity was seen at basolateral infoldings of marginal cell in stria vascularis but weak Na+-K+ ATPase activity in dark cell near transitional area. 2) There was no change of Na+-K+ ATPase activity in the stria vascularis and dark cell by systemic injection of streptomycin. The decrease of Na+-K+ ATPase activity in stria vascularis was seen at destruction site of infoldings by local infiltration of streptomycin but no changes in dark cell. 3) The ultrastructural changes of marginal cell by local infiltration of streptomycin were intracytoplasmic vacuole, partial loss of cytoplasmic infoldings, edema, and increase of melanin particle. but, there was no change of ultrastructure in dark cell except increase of melanin particle. The changes of ultrastructure of stria vascularis was variable by systemic streptomycin injection and there was no dark cell change except increased melanin particle. From the above results, the changes of ultrastructure and Na+-K+ ATPase were more severe by local infiltration of streptomycin through round window than systemic injection of streptomycin. The local infiltration of streptomycin through round window may be suitable method for the induction of inner ear damage.
Adenosine Triphosphatases*
;
Cytoplasm
;
Ear, Inner
;
Edema
;
Epithelium*
;
Gerbillinae
;
Melanins
;
Streptomycin*
;
Stria Vascularis
;
Vacuoles
6.A Case of Simultaneous Bilateral Spontaneous Pneumothorax Combined with Hemopneumothorax.
Ji Hyun LEE ; So Young LEE ; Gyn Moo KIM ; Gyeong Wu LEE ; Chi Hoon BAE ; Tae Chang JANG
Journal of the Korean Society of Emergency Medicine 2014;25(3):327-330
Bilateral pneumothorax is very rare in primary spontaneous pneumothorax patients. This condition can cause chest pain, dyspnea, and even lead to tension pneumothorax. Spontaneous hemopneumothorax can be lethal due to massive bleeding and hypovolemic shock. This condition requires precise decision making and emergency management. We report on a case of simultaneous bilateral spontaneous pneumothorax combined with hemopneumothorax in a healthy 21-year-old male patient with chest discomfort. In the emergency department, closed thoracostomy was performed for decompression of hemopneumothorax, with drainage of 850 mL of blood. Then bilateral video-assisted thoracoscopic surgery was performed successfully.
Chest Pain
;
Decision Making
;
Decompression
;
Drainage
;
Dyspnea
;
Emergencies
;
Emergency Service, Hospital
;
Hemopneumothorax*
;
Hemorrhage
;
Humans
;
Male
;
Pneumothorax*
;
Shock
;
Thoracic Surgery, Video-Assisted
;
Thoracostomy
;
Thorax
;
Young Adult
7.Cadmium Induced Acute Lung Injury and TUNEL Expression of Apoptosis in Respiratory Cells.
Kun Young KWON ; Jae Hwi JANG ; Sun Young KWON ; Chi Heum CHO ; Hoon Kyu OH ; Sang Pyo KIM
Journal of Korean Medical Science 2003;18(5):655-662
We examined the ultrastructural features of the lung parenchyma and the expression of apoptosis of the respiratory cells by TUNEL technique. Male Sprague-Dawley rats (n=30) were intra-tracheally injected with cadmium (2.5 mg/kg) into both lungs. The light and electron microscopic features of the lung tissues were examined on Days 1, 3, 7 and 10 after the injection of cadmium. Specimen preparations for the light and electron microscopic TUNEL stains were performed. Ultrastructurally, on Days 1 and 3, the alveolar spaces were filled with edematous fluid, and desquamated type I epithelial cells. On Days 7 and 10, the alveolar spaces and interstitium were patchy infiltrated with young fibroblasts and some collagen deposition. The light microscopic TUNEL stain showed that apoptosis of the alveolar cells was most prominent on Day 1, and then the number of apoptosis was markedly decreased on Days 3, 7 and 10. The electron microscopic TUNEL stain showed the electron dense homogenous nuclear expression, and the formation of intra-nuclear blebs which protrude to the outside of nuclei. On Days 7 and 10, there are frequent apoptotic nuclear bodies in the alveolar macrophages. We could examine the identification of the equivocal apoptotic cells and various morphologic expression of apoptotic nuclei on the electron microscopic TUNEL stain.
Acetone/pharmacology
;
Animals
;
Apoptosis
;
Cadmium/metabolism/*pharmacology
;
Cell Nucleus/metabolism
;
*In Situ Nick-End Labeling
;
Lung/*cytology/*injuries/pathology/*ultrastructure
;
Male
;
Microscopy, Electron
;
Microscopy, Electron, Scanning
;
Pulmonary Alveoli/metabolism
;
Rats
;
Rats, Sprague-Dawley
;
Support, Non-U.S. Gov't
;
Time Factors
8.Evaluation of the Real-Q HCV Quantification Kit.
Young Sook CHO ; Young Hoon KIM ; Kyung Hee LEE ; Hye Sun JANG ; Kyung Ah HWANG ; Yoo Li KIM ; Hyun Young CHI
Korean Journal of Clinical Microbiology 2009;12(2):72-77
BACKGROUND: Hepatitis C virus (HCV) RNA quantification is necessary for predicting the therapeutic response and assessing treatment results in patients with chronic HCV infection. Recently, real-time PCR technology for HCV RNA quantification displayed good linearity within the dynamic range. Thus, it is gradually replacing branched-DNA (bDNA) and PCR- hybridization assays. In this study, we evaluated the performance of the Real-QTM HCV quantification kit (biosewoom. Inc., Seoul, Korea) developed in Korea. METHODS: We evaluated the HCV quantification kit for detection limit, specificity, linearity, accuracy, and recovery rate of HCV RNA standard material. The results were analyzed for a correlation with those of Cobas Amplicor HCV Monitor 2.0. RESULTS: The HCV quantification kit showed a high recovery rate of HCV RNA standard material of various concentrations and amplication of HCV RNA equally in all genotypes. Hepatitis B virus and human immunodeficiency virus showed no cross-reactivity with HCV. Within-run and between-run coefficients of variation (CV) were 9.52~15.84% and 9.40~17.53%, respectively. Between-day coefficients of variation were 11.62~18.04%, and detection limit was 44 IU/mL. It showed a good correlation with Cobas Amplicor HCV Monitor 2.0 (R2=0.8954). CONCLUSION: The Real-Q HCV quantification kit showed a good specificity, sensitivity, linearity, and accuracy; therefore, we propose that it is fully adequate for monitoring antiviral therapy in patients with chronic HCV infection.
Chimera
;
Genotype
;
Hepacivirus
;
Hepatitis B virus
;
HIV
;
Humans
;
Limit of Detection
;
Organothiophosphorus Compounds
;
Real-Time Polymerase Chain Reaction
;
RNA
;
Sensitivity and Specificity
9.Three cases of post-transfusion hepatitis C.
Kyung Un NO ; Ho Seong KIM ; Ji Won CHOI ; Dong Wook KIM ; Cheol Ho JANG ; Beom Su PARK ; Jeong Kee SEO ; Gyeong Hoon KANG ; Je Geun CHI
Journal of the Korean Pediatric Society 1992;35(9):1255-1262
No abstract available.
Hepacivirus
;
Hepatitis C*
;
Hepatitis*
10.The Effects of Autologous Structural Bone Graft without Internal Fixation on Posteromedial Tibial Bone Defect in Primary Total Knee Arthroplasty.
Je Gyun CHON ; In Soo SONG ; Jun Beom KIM ; Gun Il JANG ; Chi Hoon AHN ; Ja Yeong YOON
The Journal of the Korean Orthopaedic Association 2017;52(6):514-520
PURPOSE: To evaluate the radiological and clinical outcomes of the standard total knee arthroplasty without internal fixation or extended long stem in tibial bone defect with severe varus deformity. MATERIALS AND METHODS: Between July 2012 and April 2014, 32 patients (45 cases; 4 men and 41 women with a mean age of 74.2 years) who underwent total knee arthroplasty with autologous bone grafting were enrolled for analysis. The mean follow-up period was 34.4 months. The cancellous bone defect site was exposed, and a longitudinal sulcus was made. Subsequently, a premolded bone graft was inserted in the sulcus at 45°. The defect size was measured, and the radiological and clinical results were evaluated. RESULTS: The mean defect size according to the radiograph was found to be 15.31×30.36 mm in the frontal view and 15.46×45.98 mm in the sagittal view. The mean defect size of depth during the operation was found to be 8.38 mm. The preoperative mean varus angle was 14.1° (4.0°–26.9°), and the follow-up mean valgus angle was 5.4° (0.5°–10.5°). The implant position was α=95.7°, β=90.4°, γ=2.1°, δ=89.1° on the follow-up. No implant loosening was observed, and the mean bone union period was 4.3 months. The Hospital for Special Surgery score was improved from a preoperative mean of 50.1 to a postoperative mean of 90.4. CONCLUSION: Standard total knee arthroplasty using autologous structural bone grafting without internal fixation in a tibial bone defect demonstrated a rapid, stable bone healing and excellent radiological and clinical results. Thus the index procedure was considered to be simple, and effective for bone grafting.
Arthroplasty, Replacement, Knee*
;
Bone Transplantation
;
Congenital Abnormalities
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Transplants*