Although segmental or subsegmental atelectasis may occur during anesthesia, mucous plugging of a mainstem bronchus has been uncommonly reported in anesthetized patients with chronic respiratory disease. However, pulmonary atelectasis following mucous plugging may rarely result normal patients. We report this case of an allegedly healthy patient was developed a left main stem bronchus obstruction, resulting in subsegmental collapse of left lower lung after the induction of general anesthesia.
Anesthesia* ; Anesthesia, General ; Bronchi ; Humans ; Lung ; Pulmonary Atelectasis

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BACKGROUND: Caudal block is useful when anesthesia for surgery or treatment for chronic pain is needed, but this procedure has a failure rate of up to 25% even when it performed byan experienced physician. This high failure rate is usually due to improper needle placement. METHODS: After gaining approval of the ethics committee, 46 patients received caudal blocks under ultrasound guidance; these were performed after the anatomical structures in the sacral hiatus had been measured with ultrasound. All these procedures were performed by the same anesthesiologist. The position and direction of the needle were identified using fluoroscopy by injecting a radio-opaque contrast through the needle. The time taken from thelidocaine injection to verification of the needle was measured and the planned nerve block was then carried out. RESULTS: All cases of needle insertion into the sacral canal under ultrasound guidance were successful. The average duration of the procedure and the trial count were 134.1 +/- 10.1 seconds and 1.2 +/- 0.1, respectively. In 12 of the 46 cases (26%), the needle deviated either left or right in the sacral canal, so the direction of the needle had to be adjusted. The distance between two cornua, the depth of the sacral hiatus and the thickness and length of the sacrococcygeal ligament were 17.1 +/- 0.4, 3.9 +/- 0.3, 2.3 +/- 0.1 and 24.9 +/- 0.9 mm, respectively. CONCLUSIONS: Ultrasound guidance can increase the success rate of inserting a needle into the sacral canal. However, even when ultrasound is used, the needle can deviate either left or right in the sacral canal.
Anesthesia ; Chronic Pain ; Ethics Committees ; Fluoroscopy ; Humans ; Ligaments ; Needles* ; Nerve Block ; Ultrasonography*

Phrenic nerve palsy is a well-known complication following cardiac surgery in children. The incidence is approximately 1~2%. In infants and young children, it often causes a life-threatening respiratory distress. They must be treated with mechanical ventilation in the ICU. Many patients with phrenic nerve injury who is impossible to wean from a ventilator are candidates of diaphragmatic plication. Diaphragmatic plication is performed to restore the normal pulmonary parenchymal volume by replacing the diaphragm to its proper location. This is a case of 2-months-old infant who had phrenic nerve palsy after the removal of cavernous lymphangioma of the chest. He underwent 4 operations to remove the mass and to have pericardiotomy. We tried to wean him from the ventilator but failed several times in the ICU. After 4th operation, right diaphragmatic elevation was noted from the chest X ray. Phrenic nerve palsy was confirmed with fluoroscopy and he underwent diaphragmatic plication on 42 days after his 4th operation. Three days after the diaphragmatic plication, weaning was successfully carried out.
Child ; Diaphragm ; Fluoroscopy ; Humans ; Incidence ; Infant* ; Lymphangioma* ; Paralysis* ; Pericardiectomy ; Phrenic Nerve* ; Respiration, Artificial ; Thoracic Surgery ; Thorax ; Ventilators, Mechanical ; Weaning*

STUDY DESIGN: This is a retrospective clinical study. OBJECTIVES: To compare the efficacy of lidocaine and bupivacaine for the ultrasound-guided lumbar medial branch block in chronic low back pain. SUMMARY OF LITERATURE REVIEW: There is no study for comparison of the efficacy between lidocaine and bupivacaine for the medial branch block. MATERIALS AND METHODS: From August 2011 to May 2013, 186 patients were assigned 0.5% lidocaine(n=136) or 0.25% bupivacaine(n=45) for the ultrasound-guided lumbar medial branch block. All procedures have been performed by the same operator, and 23G, 10 cm needle was placed and drug was injected under ultrasound guide. To target medial branches from lumbar spinal nerve, the groove at the root of transverse process and the base of superior articular process has been identified on transverse scan. Patients were evaluated by pre- and post-interventional(1 hour) Visual Analog Scale and analyzed statistically. RESULTS: Reduction of VAS score in bupivacaine group is significantly greater than that in lidocaine group and post-interventional VAS score in bupivacaine group is significantly lower than that in lidocaine group through analysis of covariance test with adjusted pre-interventional VAS score. In multivariate analysis, while age, sex and treatment level were not significant factors, pre-interventional VAS score and the kind of drug were significant factors. Severe pain before treatment and bupivacaine was indicator of better result. Bupivacaine group reduced pain score in the VAS 2.285 more than lidocaine group with adjustment with other factors. CONCLUSIONS: Bupivacaine is more effective than lidocaine in the reduction of pain after ultrasound-guided lumbar medial branch blocks in posterior facet joint syndrome.
Bupivacaine* ; Humans ; Lidocaine* ; Low Back Pain ; Multivariate Analysis ; Needles ; Retrospective Studies ; Spinal Nerves ; Ultrasonography ; Visual Analog Scale ; Zygapophyseal Joint

Postherpetic neuralgia (PHN) is a chronic pain syndrome associated with the reactivation of a primary varicella zoster virus infection and is one of the most serious complication of herpetic zoster. The clinical features of PHN are ongoing pain accompanied by allodynia, hyperalgesia, and paresthesia. Current treatment options aimed at relieving the symptoms of PHN include oral agents, such as, opioid, NSAIDs, antidepressants, anticonvulsants. And local anesthetics with steroids are used for subcutaneous infiltration, somatic nerve block, sympathetic nerve block and epidural nerve block. However, in some cases, the pain does not respond to this treatment. We report a case in which a patient suffering from PHN did not respond to conventional therapy, but in whom continuous intravenous infusion of magnesium and physiologic N-methyl-D-aspartate (NMDA) receptor antagonist, reduced severe pain.
Anesthetics, Local ; Anti-Inflammatory Agents, Non-Steroidal ; Anticonvulsants ; Antidepressive Agents ; Autonomic Nerve Block ; Chronic Pain ; Herpes Zoster ; Herpesvirus 3, Human ; Humans ; Hyperalgesia ; Infusions, Intravenous* ; Magnesium* ; N-Methylaspartate ; Nerve Block ; Neuralgia, Postherpetic* ; Paresthesia ; Steroids

Spontaneous intracranial hypotension (SIH), a syndrome of low CSF pressure, occurs without preceeding events such as lumbar puncture, back trauma, an operative procedure, or medical illness. Postural headache, the most characteristic symptom, usually resolves spontaneously or with bed rest, hydration, and medication. Autologous epidural blood patch is an effective management of headache in SIH patients, and here we describe a one case successfully treated 5 times with an epidural blood patch. The patient had a cardinal feature of a postural headache, low CSF pressure, and showed CSF leakages on RI cisternography. The first three epidural blood patches improved the patient's headache markedly, but the headache recurred in one month. On her second RI cisternography, we found other CSF leakage sites. After a fifth epidural blood patch the patient became asymptomatic and remained so throughout 4 months of follow up. Epidural blood patches are considered the treatment of choice in SIH patients.
Bed Rest ; Blood Patch, Epidural* ; Follow-Up Studies ; Headache ; Humans ; Intracranial Hypotension* ; Spinal Puncture ; Surgical Procedures, Operative

BACKGROUND: Previous studies have suggested synergistic analgesic drug interactions between NSAIDs and opioids in neuropathic and inflammatory pain models. The aim of this study was to investigate the analgesic drug interaction between intraperitoneal (IP) ketorolac and morphine in radiant thermal stimulation rat. METHODS: Initially, we assessed the withdrawal latency time of the hindpaw to radiant thermal stimulation every 15 min for 1 hour and every 30 min for next 1 hour after IP normal saline 5 ml (control group). The latency time was changed into percent maximal possible effect (%MPE). Next, IP dose response curves were established for the %MPE of morphine (0.3, 1, 3, 10 mg/kg) and ketorolac (3, 10, 30 mg/kg) to obtain the ED50 for each agent. And we confirmed that the IP morphine effect was induced by opioid receptor through IP morphine followed by IP naloxone. At last, we injected three doses of IP ketorolac (3, 10, 30 mg/kg) mixed with one dose of morphine (2 mg/kg) for fixed dose analysis. RESULTS: IP morphine delayed the paw withdrawal latency time dose dependently, but not ketorolac. ED50 of IP morphine was 2.1 mg/kg. And the IP morphine effect was reversed to control level by IP naloxone. IP ketorolac + morphine combination showed no further additional effects on paw withdrawal latency time over morphine only group. CONCLUSIONS: IP ketorolac did not produce antinociceptive effect during radiant thermal stimulation. There was neither additional nor synergistic analgesic interaction between IP morphine and ketorolac in thermal stimulation rat.
Analgesics, Opioid ; Animals ; Anti-Inflammatory Agents, Non-Steroidal ; Drug Interactions ; Ketorolac* ; Morphine* ; Naloxone ; Rats* ; Receptors, Opioid

BACKGROUND: The age distribution of patients with moyamoya disease (MMD) forms two characteristic peaks in children and adults. It is well known that hemorrhagic presentation is more frequent in adults, while hemorrhage is rare in children. There is controversy in the management of adult-onset MMD and its natural course is not well defined. We investigated the clinical features and outcomes of adult onset MMD to clarify its characteristics. METHODS: Fifty patients with MMD whose first manifestation appeared later than 15 years of age were studied retrospectively. The first manifestations were divided into ischemic and hemorrhagic categories. The types of reattack and their frequencies according to treatment type, as well as the differences between probable (unilateral) and definite (bilateral) MMD, and current clinical outcomes by the Modified Rankin Scale were investigated. RESULTS: The mean follow-up duration was 24.4+/-25.9 months. The female/male ratio was 1.5. The most frequent age of onset was in the 4th decade. Ischemia was more frequent (58%) than hemorrhage (40%) at the initial presentation. Reattack occurred in 20 (41%) patients and more frequently in the ischemic type (55%) than the hemorrhagic (20%). Patients with probable MMD had a later onset age (39 vs. 31.5 years old) and more frequent reattacks (50%) than patients with definite MMD (38%). Reattack occurred in 2 patients (9.5%) among 21 patients who received surgical revascularization during mean follow-up of 15.1+/-21.7 months. One patient had ischemic reattack and the other had hemorrhagic reattack after operation. Thirty five (71%) of 50 patients had good outcomes but 3 patients with hemorrhagic reattacks had poor outcomes (6%). CONCLUSIONS: Probable and definite MMD have some differences in clinical features such as onset age and reattack. Regardless of initial manifestations, most of the adult MMD patients had good outcomes. However, patients with recur-rent attacks had worse outcomes than those without reattacks, especially of the hemorrhagic type. Therefore, revention of rebleeding should receive more attention in the management of adult MMD.
Adult ; Age Distribution ; Age of Onset ; Child ; Follow-Up Studies ; Hemorrhage ; Humans ; Ischemia ; Moyamoya Disease* ; Prognosis* ; Retrospective Studies

The authors report a case of multiple spinal metastasis from a meningeal hemangiopericytoma. A 35-year-old man who had undergone radical resection of temporal hemangiopericytoma presented with a two-month history of worsening low back pain and severe radiating pain on the left leg. Radiologic examination demonstrated a tumor involving body, pedicle and facet joint on the left side of L4 compressing dural sac with large paraspinal extension. Also there was a small tumor on left side pedicle and posterior body of T10. Satisfactory results were obtained after gross total resection of tumors on both regions with posterior lumbar instrumented fusion. Unlike a well differentiated tumor on temporal lesion, the metastatic spinal lesions were anaplastic histologically. Multiple spinal metastasis should be considered after surgical treatment of cranial hemangiopericytoma.
Adult ; Hemangiopericytoma* ; Humans ; Leg ; Low Back Pain ; Neoplasm Metastasis* ; Zygapophyseal Joint