1.A case of thanatophoric dysplasia.
Tae Wook SONG ; Sang Chul HAN ; Jang Hyun NAM ; Keun Young LEE ; Sung Won KANG
Korean Journal of Obstetrics and Gynecology 1992;35(5):765-773
No abstract available.
Thanatophoric Dysplasia*
2.Expressions of the Tumor Associated Proteins and Their Correlation with the Pathologic Features in Childhood Hepatoblastoma.
Han Seong KIM ; Hyo Seop AHN ; Kwi Won PARK ; Ja June JANG
Korean Journal of Pathology 1997;31(6):538-545
Hepatoblastoma is a rare malignant liver tumor found in children. Its biological characteristics and prognostic factors have not been well known. We investigated 29 cases of hepatoblastoma, registered in university hospitals in Seoul from 1984 to 1996. By the immunohistochemical method, p53, Waf-1 (p21), bcl-2, heat shock protein 70 (hsp70), c-jun, transforming growth factor-alpha (TGF-alpha) expressions were studied. Those data were compared with clinico-pathologic features; age, sex, tumor size, tumor stage and histologic subtypes. Expression of p53 and bcl-2 were each observed separately in single cases. Expression of c-jun was more frequently noted in patients at higher stages. Expression of TGF-alpha decreased in the order of pure fetal, mixed, embryonal and small cell anaplastic subtypes. Cumulative survival rate was lower in females than in males and in patients with a higher tumor stage. According to histologic subtypes, survival rates decreased in the order of pure fetal, mixed, embryonal and small cell anaplastic subtypes. Survival rate was lower in patients with c-jun expression. Group of TGF-alpha labelling index under 19 showed a lower survival rate than that over 19. In conclusion, we found that tumor associated proteins, c-jun and TGF-alpha, are closely related to the prognosis of hepatoblastoma but p53 and bcl-2 may not be related to it.
Child
;
Female
;
Hepatoblastoma*
;
Hospitals, University
;
HSP70 Heat-Shock Proteins
;
Humans
;
Liver
;
Male
;
Population Characteristics
;
Prognosis
;
Seoul
;
Survival Rate
;
Transforming Growth Factor alpha
3.MR Findings of Tuberculous Arthritis: Significance of Tuberculoma.
Han Won JANG ; Jeen Woo KIM ; Kil Ho CHO
Journal of the Korean Radiological Society 2001;44(2):237-241
PURPOSE: To determine the magnetic resonance (MR) imaging findings of tuberculous arthritis, and the frequency-in such cases-with which tuberculoma occurs. MATERIALS AND METHODS: MR images of 26 patients (M:F, 14:12; mean age, 46.2 years) with pathologically proven tuberculous arthritis were retrospectively reviewed. The presence of joint effusion, subchondral erosion, synovial proliferation and soft tissue abscess, and whether the inner wall of this abscess was smooth, were assessed. In particular, we determined whether a nodular lesion which showed low SI on T1WI, central low SI with peripheral high SI on T2WI, and rim enhancement on contrast study, was a tuberculoma. RESULTS: The joints involved were those of the knee (n=7), hip (n=7), shoulder (n=4), sacroiliac region (n=3), elbow (n=3), and ankle (n=2). Joint effusion was noted in 15 cases (58%), and subchondral erosion in 24(92%). synovial proliferation was found in 23 cases (88%), and soft tissue abscess in 24 (92%). The inner wall of this abscess was irregular in 17 cases (71%). A tuberculoma was present in intra- or extra-articular soft tissue in 18 cases (69%). CONCLUSION: The MR findings of tuberculous arthritis were subchondral erosion, synovial proliferation, and soft tissue abscess. The presence of a tuberculoma in intra- or extra-articular soft tissue, a specific finding in tuberculous arthritis, was noted in 69% of our cases.
Abscess
;
Ankle
;
Arthritis*
;
Elbow
;
Hip
;
Humans
;
Joints
;
Knee
;
Retrospective Studies
;
Shoulder
;
Tuberculoma*
4.Antigenic potency test of hemorrhagic fever with renal syndrome-inactivated vaccine and susceptibility test from challenge of vaccinated animal with Hantaan virus.
Hae Wol CHO ; Jin Won SONG ; Young Sik JANG ; Sang Ja BAN ; Seung Han KIM
Journal of the Korean Society of Virology 1991;21(1):49-55
No abstract available.
Animals*
;
Fever*
;
Hantaan virus*
5.Cortical Involvement of Marchiafava-Bignami Disease: A Case Report.
Journal of the Korean Radiological Society 2007;56(3):217-219
Marchiafava-Bignami disease is a rare complication of chronic alcoholism and this malady typically manifests as callosal lesion. I report here on one patient with Marchiafava-Bignami disease (MBD) who has symmetric restricted diffusion in both lateral-frontal cortices, in addition to the callosal lesion.
Alcoholism
;
Corpus Callosum
;
Diffusion
;
Humans
;
Marchiafava-Bignami Disease*
6.Diffusion Weighted MRI Patterns Caused by Acute Border Zone Infarction.
Journal of the Korean Radiological Society 2008;58(1):9-15
PURPOSE: We investigated the causes and mechanisms driving acute border zone infarctions using diffusion-weighted imaging (DWI). MATERIALS AND METHODS: We analyzed DWI in 104 patients (male: 72 years, female: 32 years, age range: 44 to 84 years) with acute border zone infarction. The DWI patterns were classified as follows: pattern A- An acute border zone infarction combined with multiple small disseminated cortical infarctions, pattern B- An acute border zone infarction only. RESULTS: The most common cause of acute border zone infarctions was extracranial internal carotid artery (ICA) stenosis (45 cases, 43%). Other causes included middle cerebral artery stenosis (22 cases, 21%), intracranial ICA stenosis (14 cases, 13%), unknown, (12 cases 12%), iatrogenic (6 cases, 6%) and cardiogenic (5 cases, 5%), respectively. The most common pattern for DWI was pattern A (83 cases, 80%). We performed a transcranial Doppler in 7 of 75 cases (11%), and found at least 1 embolic pulse. CONCLUSION: The most common pattern of DWI for acute border zone infarctions was pattern A. We propose that the mechanisms driving acute border zone infarctions are emboli coupled with hypoperfusion.
Brain Infarction
;
Carotid Artery, Internal
;
Cerebral Infarction
;
Constriction, Pathologic
;
Diffusion
;
Diffusion Magnetic Resonance Imaging
;
Humans
;
Infarction
;
Middle Cerebral Artery
7.Percutaneous Transluminal Coronary Angioplasty in Total Coronary Artery Occlusion.
Won Heum SHIM ; Han Soo KIM ; Yang Soo JANG ; Seung Yun CHO ; Woong Ku LEE
Korean Circulation Journal 1992;22(4):532-539
BACKGROUND: Improvements in catheter equipments and increasing experience of the operators have brought about a broadening of the indications and applications of percutaneous transluminal coronary angioplasty(PTCA). In particular, coronary angioplasty has been employed in total occlusions.We evaluated the initial success rate and safety of PTCA total occulsive coronary artery disease. METHODS: To assess the success rate and safety of PTCA total coronary artery occlusion, the data of 24 patients(male 19, female 5, mean age 55+/-9 years), in whom PTCA for total occlusion were performed, were examined. RESULTS: Primary success rate of procedure was 66.7%(16 out of 24 lesions).The success rate according to the duration of total occlusions was 8 out of 11(72.7%) with occlusions<4 weeks duration and 3 out of 7(42.9%) with occlusions>4 weeks duration(p=0.07). There was no difference in success rate according to vassel dilate(left anterior descending 75.0%, right coronary 44.4%) and length of occluded lesion(0.93%+/-0.47%cm, p=0.35). Eight procedural failures included inability to cross the lesion with a guide wire in 6 and inability to dilate the lesion in 2, but there was no emergency coronary bypass surgery or cardiac death. CONCLUSION: Even though the recanalization of occluded coronary arteries has a lower initial success rate than angioplasty for stenotic arteries, PTCA in total occlusion can be performed as a safe and effective therapeutic modality in selective patients.
Angioplasty
;
Angioplasty, Balloon, Coronary*
;
Arteries
;
Catheters
;
Coronary Artery Disease
;
Coronary Vessels*
;
Death
;
Emergencies
;
Female
;
Humans
8.Early Results of Percutaneous Coronary Angioplasty in Multiple Lesions and Vessels.
Han Soo KIM ; Won Heum SHIM ; Yang Soo JANG ; Seung Yun CHO ; Woong Ku LEE
Korean Circulation Journal 1992;22(4):524-531
BACKGROUND: Indications and applications of percutaneous transluminal coronary angioplasty(PTCA) have been broaden recent years. We evaluated the initial success rate and safety of PTCA in mulitiple lesions and vessels. METHODS: To assess the success rate and safety of PTCA In mulitiple lesions and vessels, the data of 60 lesions from 28 patients(male 23, female 5, mean age 56+/-12 years), in whom PTCA for multiple lesions and vessels were performed, were examined. Initial results and complications were compared in 37 lesions undergoing multivessel and 23 lesions undergoing multilesion PTCA. RESULTS: Overall primary success rate of procedure was 82%(49 out of 60 lesions). Angioplasty was attempted in mean 2.1 stenotic lesions per patient. Primary success rate per lesion was 84%(31 of 37) among those who underwent multivessel and 78%(18 of 23) among those who underwent multilesion PTCA(p>0.05). Success rate according to the combination of dilated vessels was 85.7%(12 of 14) in left anterior descending(LAD) and left circumflex(LCX), 83.3%(10 of 12) in LAD and right coronary artery(RCA), 100.0%(4 of 4) in LAD and diagonal branch, RCA and LCX in 75.0%(3 of 4), and 66.7%(2 of 3) in LAD, LCX and diagonal branch. Eleven failures(18.3%) included inability to pass the guide wire cross the lesion or inability to locate the balloon catheter in 5(8,3%), abrupt closure in 2(3,3%), coronary spasm in 1(1.7%) and major branch occlusion in 3(5.0%), but there was no emergency coronary bypass surgery or cardiac death. CONCLUSION: Coronary angioplasty in selected patients with multivessel and multilesion coronary artery disease might be useful and have relatively good initial results, but the long-term efficacies with other forms of treatment must be evaluated prospectively.
Angioplasty*
;
Catheters
;
Coronary Artery Disease
;
Death
;
Emergencies
;
Female
;
Humans
;
Spasm
9.Decompressive Craniectomy for Acute Cerebral Infarction.
Heung Sun LEE ; Won Han SHIN ; Soon Kwan CHOI ; Bark Jang BYUN ; In Soo LEE
Journal of Korean Neurosurgical Society 1991;20(10-11):854-859
We present a series of 10 Patients(Seven men and three women with an average age of 53 years) who underwent decompressive craniectomy for treatment to massive brain swelling following acute cerebral infarction. Clinical signs of cerebral herniation(anisocoria or fixed and dilated pupil, and/or hemiplegia with decerebrate righidity) were present in all patients. Computed tomography and magnetic resonance imaging showed the mass effect by cerebral edema through midline shift. All patients were treated with an extensive craniectomy and duroplasty. Among them, one recovered without neurological deficit, three were moderately disabled but functionally dependent, three remained in a persistent vegetative state and three died within 9 days after surgery(good recovery=1, moderate disability=3, persistent vegetative state=3, death=3). The results suggest that decompressive craniectomy can be an useful lifesaving procedure for massive cerebral edema following widespread hemispheric infarction.
Brain Edema
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Cerebral Infarction*
;
Decompressive Craniectomy*
;
Female
;
Hemiplegia
;
Humans
;
Infarction
;
Magnetic Resonance Imaging
;
Male
;
Persistent Vegetative State
;
Prognosis
;
Pupil
10.Effect of resuspension patterns as different conditions of centrifusion in use of U bottomed microplate.
Lan Hee HAN ; Jang Soo SUH ; Kyung Eun SONG ; Won Gil LEE ; Jay Sik KIM
Korean Journal of Blood Transfusion 1991;2(1):63-68
No abstract available.