1.A Case of Prader-Willi Syndrome with Diabetes Mellitus.
Hee Ran CHOI ; Eun Ha CHOI ; Seong Hee JANG ; Young Min AHN
Journal of the Korean Pediatric Society 1994;37(4):565-572
Prader-Willi syndrome is characterized by infantile hypotonia, mental retardation, hyperhagia, hypogonadism and obesity. Approximately 60% of all PLW syndrome show an interstitial deletion of chromosome 15, 37% have apparently normal chromosome, and 3.6% have a variety of other abnormalities involving chromosome 15. Diabetes mellitus has been considered a component of PLW syndrome and the incidence is about 7%. We experienced a 17-year-old female who revealed mental retardation, hypogonadism, obesity, and non-insulin dependent type DM, compatible with Prader-Willi syndrome.
Adolescent
;
Chromosomes, Human, Pair 15
;
Diabetes Mellitus*
;
Female
;
Humans
;
Hypogonadism
;
Incidence
;
Intellectual Disability
;
Muscle Hypotonia
;
Obesity
;
Prader-Willi Syndrome*
2.A Case of Newborn Scpsis Caused by Streptococcus pneumoniae.
Eun Ha CHOI ; Seong Hee JANG ; Eun Sil DONG ; Young Min AHN
Journal of the Korean Pediatric Society 1995;38(12):1690-1693
No abstract available.
Humans
;
Infant, Newborn*
;
Streptococcus pneumoniae*
;
Streptococcus*
3.Characteristics of Potassium Channel in the Isolated Rat Detrusor Muscle.
Myeong Soo JANG ; Eun Mee CHOI ; Jeoung Hee HA ; Kang Youn LEE ; Won Joon KIM
Yeungnam University Journal of Medicine 1994;11(2):363-374
The purpose of this study was to investigate the characteristics or the potassium channels existing in the rat urinary bladders. Smooth muscle strips of rat detrusor urinae were examined by isometric myography. Relaxation responses of detrusor muscle strips to the three potassium channel openers pinacidil, a cyanoguanidine derivative, BRL 38227, a benzopyran derivative and RP 52891, a tertrahydrothiopyran derivative were examined. The potassium channel openers reduced the basal tone, and the rank order of potency was RP 52891>pincidil>BRL 38227. Procaine, an inhibitor of the voltage-sensitive potassium channel tended to increase the basal tone, but it did not affect the relaxant effects of the calcium-activated potassium channel opener did not antagonize the relaxant effects, but it reduced the Emax of RP 52891 and BRL 38227. Glibenclamide, an inhibitor of the ATP-sensitive potassium channel, antagonized the relaxant effects of pinacidil, RP 52891 and BRL 38227 reducing the Emax of RP 52891 and BRl 38227. Galanin which inhibits secretion of insulin through opening the ATP-sensitive potassium channels in pancreatic β-cells rather increased the basal tone of the isolated detrusor strips. These results suggest that the urinary bladder of the rat has mainly the ATP-sensitive, glibenclamide sensitive potassium channel, which is a different type from that in the pancreatic β-islet cells.
Animals
;
Cromakalim
;
Galanin
;
Glyburide
;
Insulin
;
KATP Channels
;
Muscle, Smooth
;
Myography
;
Pinacidil
;
Potassium Channels*
;
Potassium Channels, Calcium-Activated
;
Potassium*
;
Procaine
;
Rats*
;
Relaxation
;
Urinary Bladder
4.Subdural Hemorrhage Related to Vitamin K Deficiency in an Infant with Choledochal Cyst
Sohyung PARK ; Jang Gyu CHA ; Byung-Ha CHOI
Korean Journal of Legal Medicine 2020;44(4):163-168
The deceased was a 6-month-old male infant who was transferred to the hospital due to jaundice and vomiting. During admission, subdural hemorrhage and retinal hemorrhage were observed; additionally, a rib fracture was identified on the previous radiography images, which had eventually healed by the time of the follow-up study. This case was reported to the police, alleging child abuse, which led to a medicolegal dispute between the hospital and the deceased's parents. In addition, bleeding tendency and coagulopathy related to vitamin K deficiency were also found. The past history revealed that the deceased had diarrhea, jaundice, and experienced several episodes of acholic stools, and low levels of vitamin D at birth. On postmortem examination, the brain already revealed liquefactive necrosis, but subdural hemorrhage was still observed. The optic nerves of both eyes revealed hemorrhage with focal retinal hemorrhage.No definite fracture was identified; however, osteopenia was observed in the long bones. The liver showed septal fibrosis and cholestasis which is nearly biliary cirrhosis, and mild dilation of the intrahepatic and extrahepatic bile ducts, suggesting a choledochal cyst. This case illustrates that subdural hemorrhage related to vitamin K deficiency could occur in an infant with a choledochal cyst.When subdural hemorrhage is encountered in a child with what is considered an intentional head injury, the possibility of spontaneous hemorrhage should be excluded.
5.Two Cases of Spontaneous Rupture of the Kidney.
Nak Kyu CHOI ; Tae Eui HONG ; Chin Ha LEE ; Hwang CHOI ; Hae Soon JANG ; Sung Yel YOO ; Man Chung HAN
Korean Journal of Urology 1973;14(4):331-335
Two cases of spontaneous kidney rupture with literatural review was presented at first in Korea. 1) 56 years male patient and 25 years male patient admitted to our department of Urology through Emergency Room after onset of 2 and 1 day. after treatment at local clinic. 2) Chief complaints were one side flank pain which was followed by total gross hematuria. 3) Preoperative diagnoses were kidney rupture due to necrotic pelvic tumor in 56 years male and hypernephroma in 25 years male patient. 4) Operation was procedured at 8 days and 4 days after admission respectively. 5) The operative procedure were nephrectomy in both cases. 6) The pathological diagnoses were pelvis rupture due to renal stone and parenchymal rupture due to renal infarction in each case.
Carcinoma, Renal Cell
;
Diagnosis
;
Emergency Service, Hospital
;
Flank Pain
;
Hematuria
;
Humans
;
Infarction
;
Kidney*
;
Korea
;
Male
;
Nephrectomy
;
Pelvis
;
Rupture
;
Rupture, Spontaneous*
;
Surgical Procedures, Operative
;
Urology
6.A Case of Respiratory Syncytial Virus Infection Presented with Apnea.
Eun Ha CHOI ; Seong Hee JANG ; Young Min AHN
Journal of the Korean Pediatric Society 1996;39(4):558-561
Respiratory syncytial virus(RSV) is currently implicated as the most common and otentially serious viral respiratory pathogen of young infants. Apnea in association with RSV infection occurred in about 18% of the infants. Premature birth and a young postnatal age were risk factors for development of apnea with RSV disease. We experienced a case of RSV infection in a 37 day-old premature girl. The presenting complaint was apnea, with respiratory signs and symptoms developing later. She required mechanical ventilation.
Apnea*
;
Female
;
Humans
;
Infant
;
Premature Birth
;
Respiration, Artificial
;
Respiratory Syncytial Viruses*
;
Risk Factors
7.Pathological observations in locally advanced gastric carcinomas after preoperative chemotherapy.
Kyung Ja CHO ; Ja June JANG ; Chang Won HA ; Jae Soo KOH ; Jong In LEE ; Dong Wook CHOI ; Yoon Koo KANG
Journal of the Korean Cancer Association 1992;24(4):541-548
No abstract available.
Drug Therapy*
8.Therapeutic experience of double-cuff tenckhoff catheter in surgical patients.
Jong Yeon JANG ; Woo Song HA ; Soon Tae PARK ; Sang Kyung CHOI ; Soon Chan HONG ; Ho Seong HAN
Journal of the Korean Surgical Society 1992;42(6):825-830
No abstract available.
Catheters*
;
Humans
9.A Clinical Study on Treatment of Parathion Intoxication.
Jang Ha CHOI ; Sang Young LEE ; Kyoo Sub CHUNG
Korean Journal of Anesthesiology 1976;9(1):101-105
The Authors observed 16 cases of Parathion intoxication from 1972 to 1974 in LC.U. of Busan National University Hospital. The results were as follows; 1. Parathion solution (20%) was taken for the purpose of suicide in all 16 cases. 2. Male-to-female ratio was 1. 28: 1. Age distribution ranged from 18 to 31, and the highest age group was 2 nd decade (ll cases), next 3 rd (3 cases), and 1st decade (2 cases) in order. 3. Culture of bronchial secretion was done in 6 cases and Pseudomonas Aeruginosa were detected in 5 cases. 4. Adequate control of respiratory problems and drug therapies for this intoxication resulted.
Age Distribution
;
Busan
;
Drug Therapy
;
Humans
;
Parathion*
;
Pseudomonas aeruginosa
;
Suicide
10.Peripheral Vascular Disease in Patients with Significant Coronary Artery Disease.
Dong Hun CHOI ; Jong Won HA ; Won Heum SHIM ; Moon Hyung LEE ; June KWAN ; Si Hoon PARK ; Yang Soo JANG
Korean Circulation Journal 1995;25(2):477-482
BACKGROUND: Although it is known that patients wth peripheral vascular disease are at high risk for coronary arterial disease, however, it has not been determined that patients with coronary artery disease(CAD) correlates with peripheral vascular disease(PVD). This study was designed to determine the prevalence and clinical characteristics of peripheral vascular disease(PVD) in patients with coronary artery disease(CAD). METHODS: A total of one hundred seventy-eight patients with CAD confirmed by coronary angiogram(145 male, age 58.5+/-10.1) were included in this study from February 1992 to May 1994. Coronary and peripheral angiograms were performed in all patients and the patients were divided into two groups; patients with PVD dand patients without PVD. Clinical characteristics were compared between two groups. RESULTS: Peripheral vascular disease was present in 49 patients(27.5%) among 178 CAD patients. The mean age of patients with PVD was significantly older than that of patients without PVD. The hypertension was statistically significant difference between two groups(P<0.05). There were no major differences in the number of risk factors or number of stenotic coronary arteries in patients with and without PVD. CONCLUSION: The prevalence of PVD in patients with CAD was high and it is reasonable to state that most common risk factors for coronary and peripheral atherosclerosis were age, hypertension and obesity.
Atherosclerosis
;
Coronary Artery Disease*
;
Coronary Vessels*
;
Humans
;
Hypertension
;
Male
;
Obesity
;
Peripheral Vascular Diseases*
;
Prevalence
;
Risk Factors