1.Prevalence of early laryngeal cancer and benign vocal cord pathology among patients undergoing videostroboscopy in Philippine General Hospital from 2008 to 2010.
Carrillo Ryner Jose C ; Holgado Jan Warren A ; Hernandez Melfred L ; Tuazon Rene S
Acta Medica Philippina 2012;46(3):18-20
OBJECTIVE: To determine the types and prevalences of laryngeal pathology among patients undergoing videostroboscopy in the Philippine General Hospital.
METHODS: A systematic review of videostroboscopy records patients from January 2008 to December 2010 was perform Demographic data, risk factors, diagnosis and their associat were determined.
RESULTS: The following vocal cord pathologies were recorded the 507 subjects who underwent videostroboscopy during assessed time period: vocal cord nodules (17.4%) laryngopharygeal reflux (16.6%), vocal cord paralysis (12.8%) cyst (10.5%), polyp (8%) and laryngeal cancer (6%). Vocal cord nodules were found to be more common among professic voice users (odds ratio = 2.8). Risk factors found to be associated with cancer development include age, gender (male, odds ratio 19.8) and smoking history (odds ratio = 12.7).
CONCLUSION: The most common laryngeal pathology among patients undergoing videostroboscopy is vocal cord nodules. One out of 20 patients who underwent the procedure was given a diagnosis of laryngeal cancer.
Human ; Male ; Female ; Aged 80 And Over ; Aged ; Middle Aged ; Adult ; Young Adult ; Adolescent ; Vocal Cords ; Vocal Cord Paralysis ; Laryngeal Neoplasms ; Philippines ; Smoking ; Larynx ; Glottis ; Polyps ; Cysts
2.Basosquamous carcinoma of the neck
Jan Warren A. Holgado ; Joseph E. Cachuela
Philippine Journal of Otolaryngology Head and Neck Surgery 2011;26(1):46-48
Basosquamous carcinoma, a variant of basal cell carcinoma, is rather rare with an incidence of only 1 – 2% of cases. 1, 2 It has a predilection for the head and neck region (95.6%) with primary sites including the nasal, auricular and periocular area with the neck involved in only 1.1%.1 Unlike typical basal cell carcinoma, basosquamous carcinoma behaves more aggressively with a higher tendency for metastasis and recurrence. Its rarity translates to a lack of management guidelines. Because of its pattern of growth and relative aggressiveness, treatment plans must be well laid; recurrence resulting from poor planning may lead to a worse outcome and poorer prognosis.
Carcinoma
3.Thyroid gland involvement in advanced laryngeal squamous cell carcinoma.
Jan Warren A. HOLGADO ; Precious Eunice R. GRULLO ; Jonel Donn Leo S. GLORIA ; Alfredo Quintin Y. PONTEJOS
Acta Medica Philippina 2017;51(1):11-13
OBJECTIVE: This study aims to determine the prevalence and pattern of thyroid gland involvement in advanced laryngeal squamous cell carcinoma and to identify factors associated with its development.
METHOD: Records of 118 patients who underwent laryngectomy with thyroidectomy for advanced laryngeal squamous cell carcinoma in a tertiary government hospital from January 2010 to August 2015 were reviewed. Demographic, clinical and histopathology data were obtained. The relationship of the laterality of primary tumor bulk and lobe involvement was analyzed using Fischer's exact test. The association between thyroid gland invasion and other factors was analyzed using logistic regression.
RESULTS: Thyroid gland involvement was found in 11% of the patients via direct spread in 92.3%. Single lobe involvement accounted for 61.5% of cases. There is a tendency for laryngeal squamous cell carcinoma to invade the thyroid lobe ipsilateral to the primary tumor bulk. Extralaryngeal spread, tracheostomal involvement, and tracheal extension were associated with thyroid gland involvement.
CONCLUSION: Thyroid gland involvement in advanced laryngeal squamous cell carcinoma is rare; hence, indications for performing thyroidectomy in relation to the presence of thyroid gland involvement should be established to avoid unnecessary surgeries.
Laryngeal Neoplasms ; Thyroidectomy