PURPOSE: To evaluate the efficacy of tamoxifen, as shown by mammographic changes. MATERIALS AND METHODS: We studied the mammograms of 20 breast cancer patients treated with tamoxifen (20mg/day) and 20 patients treated with tamoxifen (20mg/day) in combination with chemothrapy. Control groups consisted of 20 breast cancer patients treated with chemotherapy and 20 healthy women; the patterns of age distribution and menstrual cycle among these participants were similar to these of the study groups. Two radiologists determined parenchymal changes as seen on follow-up mammogram, of the contralateral breast in patients with breast cancer, and of the left breast in healthy women. RESULTS: Follow-up mammogram showed decreased breast parenchyma in 75% of patients treated with tamoxifen, and in 70% of patients treated with tamoxifen and chemotherapy. Mammographic changes were not noted in 85% of patients treated with chemotherapy and in 90% of healthy women. CONCLUSION: On follow-up mammogram, breast parenchyma was seen to have been decreased by tamoxifen, used to prevent the recurrence of breast cancer and forits antiproliferative effect. Mammography might be a suitable method for determining the effect of tamoxifen.
Age Distribution ; Breast Neoplasms* ; Breast* ; Drug Therapy ; Female ; Follow-Up Studies ; Humans ; Mammography ; Menstrual Cycle ; Recurrence ; Tamoxifen*

Metanephric adenoma is a rare renal epithelial tumor. Its light microscopic features are very characteristic, and immunohistochemical and electron microscopic studies are not critical to the diagnosis. The literature indicate that, to date, the tumor has behaved in a benign fashion, and predominantly but not exclusively occurred in middle-aged women. It occurs in a wide range up to 11 cm and is usually an incidental finding but may be symptomatic with hematuria or flank pain. Recently, we have experienced a case of renal tumor showing distinctive adenomatous features, which is incidentally found in a 52-year-old female. This tumor is confined to the renal cortex and is well-circumscribed with a characteristic uniform and orderly proliferation of compact well-differentiated small tubules lined by bland oval cells with a very low level of mitotic activity. The term metanephric adenoma is appropriate for this tumor because it accurately describes its bland proliferation of tubules and reflects the embryonic architectural and cytological appearance of this proliferation. The pattern of the tumor, with its occasional papillary glomeruloid- like bodies and foci of elongated tubules, is reminiscent of the fetal metanephric kidney.
Adenoma* ; Diagnosis ; Female ; Flank Pain ; Hematuria ; Humans ; Incidental Findings ; Kidney* ; Middle Aged

BACKGROUND: Trauma is the third leading cause of death, irrespective of age, and the leading cause of death in persons under 40 years of age. Computed tomography (CT) is an effective technique in the initial emergent evaluation of the abdomen and head following blunt trauma. Most chest indies are not seen on conventional chest radiography, or may be underestimated. But routine use of CT in the initial emergent evaluation of chest trauma is controversial. CT, however, has been shown to be useful in the diagnosis of unsuspected chest injuries and in directing therapeutic interventions. This review discusses the efficacy of emergent CT in patients with blunt trauma on the chest. METHODS: To evaluate the efficacy of CT of the thorax, a retrospective study comparing early thoracic CT scanning with initial chest roentgenogram(CXR) was carried out on 121 patients with blunt trauma on the chest. The interval between CXR and CT was less than 1 hour. RESULTS: Among 121 patients, 42 patients had normal initial chest roentgenogram in whom 19 patients showed normal CT findings. Sensitivities of diagnosing pneumothorax and pleural effusion by CXR were low (49.3%and 45.1%respectively), whereas 65.7% (44/67) of patients had thoracostomy only by CXR. CONCLUSIONS : Although sometimes abused in patients with chest trauma, CT of the thorax is an effective method of detecting thoracic injuries and provides accurate information regarding their pattern and extent in the initial emergent diagnosis.
Abdomen ; Cause of Death ; Diagnosis ; Emergencies* ; Head ; Humans ; Pleural Effusion ; Pneumothorax ; Radiography ; Retrospective Studies ; Thoracic Injuries ; Thoracostomy ; Thorax* ; Tomography, X-Ray Computed

An autopsy case of holoacardius hemisomus acephalus is reported. She weighed 2,190 gm and the height was 38 cm. The head and upper extremities were absent, while the vertebrae and lower extremities were relatively well developed, but severely edematous. The heart, lungs, stomach, liver, spleen, and pancreas were missing, but the lower abdominal organs including kidneys, adrenal, urinary bladder, and genital organs were present. The intestine was blind-ended at jejunal level but opened into a normal anus. The umbilical cord had two arteries and one vein.

No abstract available.
Knee*

Cervix Uteri ; Diagnosis, Differential ; Female ; Humans ; Lip ; Malocclusion

No abstract available.
Dermatitis, Allergic Contact

Three cases of successful pregnancy outcome after intensive care in the patients with rare mullerian anomaly of complete uterine septum, hypoplastic cervical duplication and longitudinal vaginal septum in infertility clinic are reported. These presented three cases are the reports of supporting the embryologic hypothesis of bidirectional mullerian development which fusion and resorption begins at the isthmus and proceeds simultaneously in both the cranial and caudal directions rather than the classical views of unidirectional(caudal to cranial) mullerian development. Thus, we present here three cases of rare mullerian anomaly and their pregnancy outcomes in an attempt to alert gynecologist to the possible occurrence of such a malformation. In 2 cases, successful pregnancy outcomes were achieved after abdominal or hysteroscopic uterine septotomy before pregnancy and in the last case, successful pregnancy outcome intensive obstetric care was achieved even under uncorrected uterine anomaly and complete removal of uterine septum resulted in uneventful postoperative courses at the same time of cesarean section.
Cesarean Section ; Female ; Humans ; Infertility ; Critical Care* ; Pregnancy ; Pregnancy Outcome* ; Pregnancy*

A study was carried out to see the knowledge, attitude and practice of mothers in regard to infant and child health through enquete. The questionnaires were filled up by 350 mothers who registered at Well Baby Clinic, National Medical Center, during two months period from March, 1980 to April, 1980. The survey intended to look into maternal knowledge and attitude toward pregnancy, prenatal care, nutritional care, vaccination and health care. The following conclusions were obtained. 1. Among the mothers enrolled in this study, the age group in 25~29 constituted the largest proportion(58.3%) and the mean age was 28.0 years. 2. High school graduates occupied the largest proportion(48.1%) of the respondents. 3. The most frequent age of the first delivery was in 25~29(63.7%) years. 4. Concerning the knowledge on pregnancy, delivery and child rearing, the majority of the primary school graduates learned from their parents in law, the middle & high school graduates acquired through reading books or magazines and the college graduates learned by school education. 5. Regular prenatal cares were taken in 70% of the respondents. 6. Regarding the knowledge about the influences on fetus of the diseases during pregnancy, there noted the difference among the respondents by education, and most of them notified ventral diseases and tuberculosis as the diseases most concerned. 7. Breast feeding only was done in 50% of the respondents until the 3 months of age of the infants, and bottle feedings supplemented by solid foods or other was the most common type of feeding after 3 months of age to 15 months of age followed by adult type diet afterwards. 8. Relation between the educational level of mothers and the method of infant feeding disclosed that the higher the education level, the higher the bottle feeding. 9. About 71% of the mothers replied that they know the significance or the necessity of the weaning. The ideal starting period of weaning was thought 4~6 months in 58.6% of the respondents. 10. The most common initial weaning food was fruits and vegetables(50.4%) followed by cereals(18.7%) and commercial weaning food products(17.4%) 11. Regarding the most important nutrient in infants and children, they notified vitamins most commonly(46.9%) and more than half of them supplied the vitamins to their infants. 12. About 42% of all mothers know the beginning period of primary vaccinations as 2 months of age, 69.7% of them recognized the next vaccinations and 77.1% of them immunized their infants as schedule. 13. Most of the mothers(96.6%) realized the necessity and importance of the vaccination. A few mothers, however, had knowledge on the side effects of DPT vaccination. 14. The most concerned problem with regard to health care was the illness(42.9%). In more than half, health care was provided only on well baby clinic visits.
Adult ; Ambulatory Care ; Appointments and Schedules ; Bottle Feeding ; Breast Feeding ; Child ; Child Rearing ; Child Health* ; Child* ; Surveys and Questionnaires ; Delivery of Health Care ; Diet ; Education ; Fetus ; Fruit ; Humans ; Infant* ; Jurisprudence ; Mothers ; Parents ; Periodicals as Topic ; Pregnancy ; Prenatal Care ; Tuberculosis ; Vaccination ; Vitamins ; Weaning

The oropharyngeal swallow of 26 patients with dysphagia was studied quantitatively and qualitatively using videofluoroscope. Videofluoroscopic examination was done with head in neutral position, and with three different c onsistency of test meals; thin liquid, thick liquid, and solid, When aspiration or laryngeal penetration was noted in neutral position, the study was repeated with different head positions, We compared them with each other and with 25 normal subject(previously presented). 11/26(42%) patients revealed laryngeal penetration or aspiration at least with one consistency of test meal. Aspiration occurred more frequently in thin liquid than thick liquid or solid, Head position change successfully eliminated aspiration in 10/10 patients(100%). Other one patient could not change his head position. 9 numerical parameters were derived and calculated for quantitative examination, Liquid meal oral discharge time, pharyngeal delay time, and pharyngeal transit time were significantly increased in patients with aspiration than in patients without aspiration. Also significantly increased than those of normal controls. Because different test meal consistency gave different values, direct comparison of values regardless of meal consistency was fruitless. And because all the process of swallowing cannot be expressed as numerical parameters qualitative examination of videofluoroscopic result was essential. In conclusion, liquid meal oral discharge time, pharyngeal delay time, and pharyngeal transit time were useful parameters in differentiating and quantifying dysphagia. Aspiration can be reduced when appropriate position assumed. Calculated values were different a according to the consistency of the test meal. Quantitative analysis was helpful, but qualitative examination of videofluoroscopy was essential.
Deglutition Disorders* ; Deglutition* ; Head ; Humans ; Meals ; Posture* ; Viscosity*