No abstract available.
Burns* ; Humans

No abstract available.
Burns* ; Humans

No abstract available.
Contrast Media* ; Magnetic Resonance Imaging*

The allopurinol hypersensicivity syndrome is a rare, but life thereaning immunologic reaction of allopurinol therapy, characterized by multiple abnormalities such as fever, rash, decreased renal function, hepatocellular injury, leukocytosis, and eosinophila. It may require prolonged hospitalization and occasionally involves residual morbidity. Three patients developed erythematous skin eruption three to five weeks after beginning therapy with allopurinol. The clinical, laboratory, and histologic findings of these patients were compatible with a allopurinol hyperensitivity syndrome.
Abnormalities, Multiple ; Allopurinol* ; Exanthema ; Fever ; Hospitalization ; Humans ; Hypersensitivity* ; Leukocytosis ; Skin

We report a case of hereditary angioedema in a 48-year old female patient. She experidenced facial edema and dyspnea 5 to 6 times for a year. Similar episodes developed on some members of her family, especially her sisters and father. We examined her and her sister's serum complement levels. The results showed decreased levels of C1 esterase inhibitor and C4, compared to normal levels. We treated the patient with danazol effectively.
Angioedemas, Hereditary* ; Complement C1 Inhibitor Protein ; Complement System Proteins ; Danazol ; Dyspnea ; Edema ; Fathers ; Female ; Humans ; Middle Aged ; Siblings

BACKGROUND: Chronic cutaneous lupus erythematosus(CCLE) is a well-known disease entity. But there has been no data about its clinical behavior and histopathologic features in Korea. OBJECTIVES: This study was conducted to elucidate the clinical, laboratory, and histopathologic features of CCLE, and the relationship between CCLE and SLE. MATERIALS AND METHODS: We investigated 48 cases of CCLE that visited the department of dermatology at the Seoul National University Hospital from January 1990 to June 1997. Medical records and biopsy slides were reviewed.
Biopsy ; Dermatology ; Korea ; Lupus Erythematosus, Cutaneous* ; Medical Records ; Seoul

Gout is a hereditary condition of disturbed uric acid metabolism in which urate salts are deposited in articular, periarticular and subcutaneous tissues. Clinically, it is characterized by recurring attacks of acute arthritis, intervals of freedom from pain, and in late stages by crippling deforming arthritis, nephritis, urinary calculi and cardiovascular lesions. Seventeen patients with gout managed at the department of orthopedic surgery, National Police Hospital, from February, 1972 to December, 1977, were reviewed and the following results were obtained. 1. Most of cases were between 30 and 49 years old and all the cases were male. 2. The most common season of occurrence of acute attack was winter and the least common season was summer. 3. The recurring attacks were more frequent than the first attacks. 4. The precipitating factors could be found usually including family history, dietary indiscretions, exposure to cold and stress conditions. 5. The average serum uric acid level during acute attacks showed 12. 9mg% and all the cases except 2 cases noted increased ESR with average 33.9mm/hr. The leucocytosis were noted in 6 cases. 6. The first involved joints were the M-P joint of big toe in 13 cases and the knee joint in 3 cases. 7. The radiological multiple punched-out bone lesions were found in 8 cases. 8. One tablet (0. 65mg) of colchicine was given every hour until the diarrhea appeared or the pain subsided, in 13 cases. Among them, when 10 tablets of colchicine were taken, the diarrhea appeared in 10 cases and the pain subsided in 8 cases. So we recommend 7~8 tablets for relief of G-I discomfort in management of gout. 9. The cases of gouty arthritis may be found more and more in our country because the stress condition and meat intake might be increased such as in Europe and America.
Americas ; Arthritis ; Arthritis, Gouty ; Colchicine ; Diarrhea ; Europe ; Freedom ; Gout ; Hallux ; Humans ; Joints ; Knee Joint ; Male ; Meat ; Metabolism ; Nephritis ; Orthopedics ; Police ; Precipitating Factors ; Salts ; Seasons ; Subcutaneous Tissue ; Tablets ; Uric Acid ; Urinary Calculi

One case of Pseudo-Pseudohypoparathyroidism is reported with the characteristic body features such as short stature, round face, metacarpal sign and multiple exostoses.
Exostoses, Multiple Hereditary ; Pseudopseudohypoparathyroidism

Purpose: Echocardiography is useful in the management of critically ill patients, but there are few studies on the usefulness of an echocardiography for critical general surgery patients. This study aimed to address this by analyzing the indications and findings for and clinical outcomes between (1) chest trauma; (2) cardiac specific pathology; and (3) hemodynamic instability groups of critical general surgery patients
Methods: Retrospective analysis was performed on the medical records data from the last 5 years of general surgery patients who were admitted to the intensive care unit (ICU) and had an echocardiography at least once during their ICU stay. The patient data were divided into 3 groups according to the indication for an echocardiography and based on the clinical situation. Demographics, the ratio of positive echocardiography findings, and clinical outcomes including the length of hospital stay, length of ICU stay, and in-hospital mortality were analyzed among these groups.
Results: There were statistical differences in the rate of positive echocardiography findings (p = 0.018) and in-hospital mortality (p = 0.001) amongst the groups with different echocardiography indications; there was no difference in the length of stay. Patients who had an echocardiography due to hemodynamic instability or cardiologic pathology presented with a higher ratio of positive echocardiography findings and mortality, compared with the chest trauma patient group. The chest trauma group showed the lowest rate of positive echocardiography findings (7%).
Conclusion Echocardiographies are useful for general surgery patients in ICUs when there are indications such as previous cardiac pathology history or hemodynamic instability.

Purpose: Echocardiography is useful in the management of critically ill patients, but there are few studies on the usefulness of an echocardiography for critical general surgery patients. This study aimed to address this by analyzing the indications and findings for and clinical outcomes between (1) chest trauma; (2) cardiac specific pathology; and (3) hemodynamic instability groups of critical general surgery patients
Methods: Retrospective analysis was performed on the medical records data from the last 5 years of general surgery patients who were admitted to the intensive care unit (ICU) and had an echocardiography at least once during their ICU stay. The patient data were divided into 3 groups according to the indication for an echocardiography and based on the clinical situation. Demographics, the ratio of positive echocardiography findings, and clinical outcomes including the length of hospital stay, length of ICU stay, and in-hospital mortality were analyzed among these groups.
Results: There were statistical differences in the rate of positive echocardiography findings (p = 0.018) and in-hospital mortality (p = 0.001) amongst the groups with different echocardiography indications; there was no difference in the length of stay. Patients who had an echocardiography due to hemodynamic instability or cardiologic pathology presented with a higher ratio of positive echocardiography findings and mortality, compared with the chest trauma patient group. The chest trauma group showed the lowest rate of positive echocardiography findings (7%).
Conclusion Echocardiographies are useful for general surgery patients in ICUs when there are indications such as previous cardiac pathology history or hemodynamic instability.