1.A Case of Malignant Pyoderma.
Jee Ho CHOI ; Jai Il YOUN ; Yoo Shin LEE
Korean Journal of Dermatology 1984;22(4):413-417
Malignant pyoperma is a rare, chronic, progressive, destructive ulcerating skin disease of unknown cause that affects the head and neck region of young adults. The disease is progressive but responds to high doses of systemically administered steroids. We present a case of malignant pyoderma developed on the left retroauricular area in 67 year-old male. The patient died of rapidly progressive, desructive, 15cm x 20 cm sized, phagedenic ulcer on the left retroauricular and neck area despite of various extensive local and systemic treatment. Histopathologic findings of tissue from the edge of the ulcer were non-specific, showing upper dermal necrosis and mixed inflammatory cell infiltrate in the deep dermis.
Aged
;
Dermis
;
Head
;
Humans
;
Male
;
Neck
;
Necrosis
;
Pyoderma*
;
Skin Diseases
;
Steroids
;
Ulcer
;
Young Adult
2.Reconstruction of the foot by first web space island flap.
Hyun Ho KIM ; Byung Il PARK ; Jai Koo CHOI
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(2):273-280
No abstract available.
Foot*
3.An Immunohistochemical Study of Molluscum Contagiosum.
Ho Seok SUH ; Jee Ho CHOI ; Kyung Jeh SUNG ; Jai Kyoung KOH
Korean Journal of Dermatology 1994;32(5):787-794
BACKGROUND: Molluscum contagiosum is a common viral infect oudisease of the skin and mucous membrane that is caused by a molluscum contagiosum virus(MCV; which belongs to the poxviridae family. One of the characteristic histopathologic findings is an epidermal hyperplasia Porter and Archard reported that this phenomenon might be explained by a virus induced epidermal growth factor (EGF) like polypeptide. There was a report that epidermal prolifeation in viral infection might be modulated by other factors than the virus itself such as local immune response. OBJECTIVE: The purpose of this study was to examine the expression pattern of epidermal growth factor receptor and other immunocompetent cells by immunohistochemical stainings. METHOD : We performed iinmunoperoxidase staining on the 11 slaecmens of formalin-fixed, paraffin-embedded molluscum lesions and 15 specimens of snap frozen mollucum lesions with nine primary antibodies(EGFR, factor XIIIa, CDla, S-100 protein, MAC 387, HLA-IR, CD4, CDS, L26) RESULTS: EGF receptors were strongly expressed in lesional MCV ifect,ed keratinocytes. The number of CDla and factor XIIIa positive dermal dendritic cells were sigtly increased. In inflamed lesions, CD4 and HLA-DR expressions were increased in the dermis and per lesional epidermis. CONCLUSION: This study shows that 1) increased EGFR expression is of MCV infected keratinocytes may be related to the pathogenesis of epidermal hyperplasia. 2) helper T lyrnphocytes may operate in inflamed molluscum lesions.
Dermis
;
Epidermal Growth Factor
;
Epidermis
;
Factor XIIIa
;
HLA-DR Antigens
;
Humans
;
Hyperplasia
;
Keratinocytes
;
Langerhans Cells
;
Molluscum Contagiosum*
;
Mucous Membrane
;
Poxviridae
;
Receptor, Epidermal Growth Factor
;
S100 Proteins
;
Skin
4.Immunohistochemical study on sweat gland tumors with monoclonal antibodies against S-100 subunits.
Kyung Jeh SUNG ; Kwang Hyun CHO ; Ho Seok SUH ; Jee Ho CHOI ; Jai Kyoung KOH
Korean Journal of Dermatology 1992;30(4):446-453
S-100 protein is a mixture of three proteins, that is, S-100 ao(aa), S-100 a(ab) and, S- 100 b(bb). Twenty-two case, of sweat gland tumors were stained with immunoperoxidase technique (ABC method) for the presence of S-100a and b-subunit. Four syringomas, four eccrine poromas, two eccrine porocarcinomas, two ecerine spirdeiomas, one papillary eccrine adenoma, three clear cell hidradenomas, three mixed tumr rs of the skin, two papillary syringocystadenomas, and one cylindroma were included. All specimens were formalin-fixed and paraffin-embedded. The results were as follows : 1) The staining patterns of anti-S-100a and b-protein antibodies we e simillar to those of anti-S-100 protein antibody except in eccrine poroma and porocare nomal. 2) In eccrine poroma and porocarcinoma, scattered S-100-positive dendritic cells within tumor cell nests were stained by S-100-protein antibody (3/6), but not by anti-S-100a protein antibody. S-100p is present in normal Langerhans cells. Therefore this finding suggests that these cells niay be Langerhans cells
Acrospiroma
;
Adenoma
;
Antibodies
;
Antibodies, Monoclonal*
;
Carcinoma, Adenoid Cystic
;
Dendritic Cells
;
Eccrine Porocarcinoma
;
Immunoenzyme Techniques
;
Langerhans Cells
;
Poroma
;
S100 Proteins
;
Skin
;
Sweat Glands*
;
Sweat*
;
Syringoma
5.A Case of Trichoblastic Fibroma.
Hwa Jung LEE ; Dong Jin IM ; Ho Seok SUH ; Jee Ho CHOI ; Jai Kyoung KOH
Annals of Dermatology 1996;8(4):265-268
Trichogenic tumors are very rare and described as cutaneous neoplasms probably derived from hair germ which develops into hair follicles. We report a case of trichoblastic fibroma on the left parietal scalp of a 45-year-old man. The lesion was a solitary, firm, non-tender, 2×2cm subcutaneous nodule. The histopathological study showed a well circumscribed dermal tumor composed of abundant basophilic palisading basaloid lobules with some keratinous cysts, hair follicle differentiation and fibroblastic stroma.
Basophils
;
Fibroblasts
;
Fibroma*
;
Hair
;
Hair Follicle
;
Humans
;
Middle Aged
;
Rabeprazole
;
Scalp
6.Three Cases of Neutrophilic Eccrine Hidradenitis.
Ho Seok SUH ; Moon Soo YOON ; Jee Ho CHOI ; Kyung Jeh SUNG ; Jai Kyoung KOH
Annals of Dermatology 1995;7(2):200-205
Neutrophilic eccrine hidradenitis(NEH) was originally described in 1982 by Harrist et al. in a patient with myelogenous leukemia receiving chemotherapy. Clinically NEH represents various cutaneous manifestations with or without tenderness and pruritus. Histologic examination demonstrates a neutrophilic infiltrate within and around the eccrine gland and degeneration of the eccrine gland structures. Although the pathogenesis and possible cause of NEH remain unknown, it is probably an unusual cutaneous reaction to chemotherapeutic agents. A few cases of infection associated eccrine hidradenitis are found in the literature. We report three cases of neutrophilic eccrine hidradenitis. Two cases were associated with hematologic malignancy. The third case was associated with an infection of Vibrio vulnificus.
Drug Therapy
;
Eccrine Glands
;
Hematologic Neoplasms
;
Hidradenitis*
;
Humans
;
Leukemia, Myeloid
;
Neutrophils*
;
Pruritus
;
Vibrio vulnificus
7.A Case of Acquired Digital Fibrokeratoma: Immunohistochemical Stain with Anti - factor XIIIa antibody.
Ho Seok SUH ; byung Jick RYU ; Jee Ho CHOI ; Kyung Jeh SUNG ; Jai Kyoung KOH
Korean Journal of Dermatology 1994;32(6):1131-1135
In normal hurnan dermis, factor XIIIa positive dermal dendrocyte are located in the papillary areas closely associated with blood vessels and the upper reticular dem These cells represent a specific type of bone marrow derived dermal cells, distinct from Langerhans cells having some features in common with rnonocyte/macrophage lineage and with potential antier presenting activity. Although the significance of these cells has not yet been fully established, it been suggested that they play a major role in skin immune iesponses, in collagen synsthesis regultic and in wound repair. We report a case of acaqired fibrokeratoma which is studiec conventional histopathology and immunohistochemistry. Histopathologic findings of this case showed ovascular proliferation and the increased presence of fibroblast like cells as a common fe;ture of these benign tumors. Immunohistochemical staining with anti factor XIIIa antibody deiaoi strates increased numbera of positive dendritic cells in the upper dermis. There finding supports the fat that some fibroblagt like cells in the upper dermis of acquireid fibrokeratoma may be factor XIIIa positive dermal dendritic cells.
Blood Vessels
;
Bone Marrow
;
Collagen
;
Dendritic Cells
;
Dermis
;
Factor XIIIa*
;
Fibroblasts
;
Immunohistochemistry
;
Langerhans Cells
;
Skin
;
Wounds and Injuries
8.A case of multiple lentigines syndrome.
Mi Woo LEE ; Jee Ho CHOI ; Seung Chul LEE ; Kyung Jeh SUNG ; Jai Kyoung KOH
Korean Journal of Dermatology 1993;31(5):780-783
Supernunmerary nipple is a developmental anomaly occuring alon, the course of the embryological milk lines. This entity has receieved little attention in the dermatologic literature and has been confused with a pigmented nevus in some cases. We have experienced two ease of the more unusual form of supern umerary nipple. According to the Kajavas classification, our caes are classified as polithelia pilosa and complete breast with nipple
Breast
;
Classification
;
LEOPARD Syndrome*
;
Milk
;
Nevus, Pigmented
;
Nipples
9.Confluent and Reticulated Papillomatosis Successfully Treated with Minocycline.
Sun Young LEE ; Jee Ho CHOI ; Kyung Jeh SUNG ; Kee Chan MOON ; Jai Koung KOH
Annals of Dermatology 2000;12(1):33-37
Confluent and reticulated papillomatosis (Gougerot and Carteaud) is a rare but clinically distinct dermatosis of which the etiology is unknown. We report 2 cases. One case is a 16-year-old boy who had a hyperpigmented reticulated eruption on the trunk and both arms and the other case is a 33-year-old man who had a similar eruption on the chest and back. The former, with previous treatment with oral and topical antifungal agent in another clinic didn't show any improvement and the latter case, with initial treatment of itraconazole did not improve his skin lesion. The rashes of two patients virtually disappeared with administration of minocycline. These observations indicate that the role of microorganisms sensitive to minocycline or anti- proliferative effect of minocycline could be presumed.
Adolescent
;
Adult
;
Arm
;
Exanthema
;
Humans
;
Itraconazole
;
Male
;
Minocycline*
;
Papilloma*
;
Skin
;
Skin Diseases
;
Thorax
10.The Values of Calcium, Uric Acid, Magnesium and Magnesium/Calcium Ratio in Urine with the Urinary Calculi.
Gil Ho LEE ; Jai Hun CHOI ; Jae Heung CHO
Korean Journal of Urology 1987;28(6):815-820
There was no definitive reported cases of urinary calculi. This study is to estate the value of urinary calcium, magnesium, uric acid and magnesium/calcium ratio in cases of urinary calculi. The amount of calcium, uric acid and magnesium in 24 hour urinary excretion was measured by OCPC, Uricase and titan yellow method in 56 cases of upper urinary calculi compared with 35 control group.The results were summerized as follows.l. The mean values of 24 hour urinary excretion of calcium were 193+/-26mg/day in stone formers and 15l+/-25mg/day in control group. The 24 hour urinary excretion of calcium in the stone formers were significantly higher than those of the control group. 2. The mean values of 24 hour urinary excretion of uric acid were 498+/-40mg/day in the stone formers and 371+/-6mg/day in the control group. The 24 hour urinary excretion of uric acid in the stone formers were significantly higher than those of the control group. 3. Urinary magnesium values have not been shown any significant differences between the group with urinary calculi and those of control group. 4. The mean values of 24 hour urine of magnesium to calcium ratio was 1.01+/-0.95 in stone formers and l.42+/-1.31 in the control group. The magnesium to calcium ratio in the stone formers were significantly lower than those of the control group. These results suggest that increased urinary calcium and uric acid level may play some role in the genesis of urinary stone but urinary magnesium value was not different in the two groups. We think that a decrease in the urinary magnesium to calcium ratio was the results of increased excretion of calcium rather than lowered excretion of the magnesium for the stone formers.
Calcium*
;
Magnesium*
;
Saturn
;
Urate Oxidase
;
Uric Acid*
;
Urinary Calculi*
;
Urolithiasis