Luteal phase defect (LPD) is an ovulatory disorder of considerable clinical importance that leads to delayed endometrial maturation and inadequate endometrium for blastocyst implantation. This disorder is implicated in infertility and recurrent spontaneous abortion. We analyzed the endometrial histological maturation, and the estrogen receptor(ER) and progesterone receptor(PR) status in patients with unexplained delayed ovulation, and in patients with ovulation induction by clomiphen citrate. The purpose of this study was to determine whether the length of the follicular phase influences the endometrial histological maturation and the hormonal receptor status, and to know the effect of clomiphen citrate on the endometrium. In the delayed ovulation group, the endometrium was characterized by an irregular outpouching and dilated lumina of the glands, a decreased secretory activity and predecidualization, and a decreased number of granulocytes in the stroma. In the clomiphen citrate-ovulation induction group, glandular proliferation was markedly diminished with poorly convoluted and narrow glands, secretory activity was decreased, stroma was undecidualized, and there was an absence of granulocytes. ER expression was increased in the glandular epithelium in the delayed ovulation group, and both ER and PR expressions were markedly decreased in the glandular epithelium and stromal cells in the ovulation induction group. Endometrial maturation and differentiation may be diminished by increased estrogenic and relatively deficient progesterone effects in patients with delayed ovulation. The hormonal receptor status might also be influenced by hormonal changes. Clomiphen citrate successfully induced ovulation in patients with delayed ovulation, however, endometrial proliferation and maturation were markedly suppressed. This might be related to the lower pregnancy rate and higher abortion rate in patients with clomiphen citrate induced ovulation.
Pregnancy ; Female ; Humans

Trichogenic tumors are very rare and described as cutaneous neoplasms probably derived from hair germ which develops into hair follicles. We report a case of trichoblastic fibroma on the left parietal scalp of a 45-year-old man. The lesion was a solitary, firm, non-tender, 2×2cm subcutaneous nodule. The histopathological study showed a well circumscribed dermal tumor composed of abundant basophilic palisading basaloid lobules with some keratinous cysts, hair follicle differentiation and fibroblastic stroma.
Basophils ; Fibroblasts ; Fibroma* ; Hair ; Hair Follicle ; Humans ; Middle Aged ; Rabeprazole ; Scalp

Lymphangiomas are made up of multiple lymphatic channels lined by benign-appearing endothelial cells. The lesions can occur anywhere in the body but most commonly affect head, neck and axilla. It rarely involves the gastrointestinal tract and particularly lymphangioma of the colon is very rare. Histologically, it is classified three types as simple or capillary, cavernous, and cystic. We experienced three cases of cavernous lymphangioma of the ascending colon. Case 1, 56-year-old male, had lymphangioma accompanied by ulcerating cancer of the cecum. Case 2, 51-year-old female, had lymphangioma of cecum. Case 3, 41-year-old male had lymphangioma at ileocecal valve. All cases could be diagnosed by colonoscopic snare polypectomy.
Adult ; Axilla ; Capillaries ; Cecal Neoplasms ; Cecum ; Colon* ; Colon, Ascending ; Endothelial Cells ; Female ; Gastrointestinal Tract ; Head ; Humans ; Ileocecal Valve ; Lymphangioma* ; Male ; Middle Aged ; Neck ; SNARE Proteins ; Ulcer

OBJECTIVE: To investigate the prevalence of airway hyperresponsiveness induced by isocyanate at one petrochemical industry complex in Yeochon, Korea. METHOD: Questionnaires, allergic skin prick test, toluene diisocyanate (TDI)-specific IgE, and non-specific airway hyperresponsiveness (AHR) were studied in 73 exposed workers and 27 control subjects. Methacholine challenge tests were done and bronc hial responsiveness (BR index) was defined as log (% fall of FEV1)/ log (last concentration of methacholine +10). RESULTS: Twenty-three workers (31.5% ) had respiratory symptoms, 21 had nasal symptoms, and eight had skin symptoms. Exposed workers with respiratory symptoms (n=22) had significantly higher BR index than those without them (0.82+/-0.06 vs 0.60+/-0.02, p<0.05). Exposed workers tended to have higher BR index than controls (0.67+/-0.03 vs 0.62+/-0.02). Three exposed workers had PC20 methacholine <2.0 mg/ml. There were no significant differences in atopy score between exposed workers and controls (p>0.05). Specific IgE antibodies were found in 19.7% of exposed workers. FEV, showed a significant negative correlation with BR index (r =-0.25, p<0.05). Poor correlation was noted between BR index and atopy, smoking status, or exposure duration. CONCLUSION: These findings suggest that workers exposed to isocyanates are at higher risk of airway hyperresponsiveness.
Antibodies ; Immunoglobulin E ; Isocyanates* ; Korea ; Methacholine Chloride ; Plants* ; Prevalence ; Skin ; Smoke ; Smoking ; Toluene 2,4-Diisocyanate ; Surveys and Questionnaires

Acute food impaction of the esophagus is not an unusual problem on an emergency ward. It has been termed the Steakhouse syndrome or the Backyard barbecue syndrome, indicating that meet is the obstrueting bolus in the majority of cases. Most esophageal stenoaes are located distally, and this ie also the area where most food impations occur. The obstruction quickly becomes apparent to the patient when further swallowing of food or liquid is impossible. Various obstructive lesions or motility disorders of the esophagus have been implicated as etiological factors in acute food impaction. Common,disorders include reflux esophagitis with stricture, hiatal hernia, abnormal rings and postoperative strictures at anastomotic sites. Malignant stenoses have been very rarely described. Recently we experienced of 4 patients who suffered from acute dysphagia after they had ingestion of food such as beef, pork, chicken, and dog meat, repectively. All of them were diagnased as steakhouse syndrome due to acute food impaction of the esophageal after examinations of esophagogram and endoscopy. They had hiatal hernia, esophageal cancer, reflux esophagitis with stricture, and abnormal ring as underlying diseases, repectively. All of them were treated with endoseopic removal of foreign body by a Dormia basket.
Animals ; Chickens ; Constriction, Pathologic ; Deglutition ; Deglutition Disorders ; Dogs ; Eating ; Emergency Service, Hospital ; Endoscopy ; Esophageal Neoplasms ; Esophagitis, Peptic ; Esophagus* ; Foreign Bodies ; Hernia, Hiatal ; Humans ; Meat

Febrile morbidity after cesarean section is one of the major problems in obstetric practice. This morbidity is most often due to endometritis. Although parenteral prophylactic antibiotics or antibiotic irrigation has been reported to reduce the incidence of endometritis after cesarean section, its incidence remains high. Among the patients who were undergoing cesarean section at Yeungnam University Hospital from the beginning of March, 1985, three group were evaluated in the orders. 1) 30 cases as intrauterine irrigation group with cephradine solution, 2) 35 cases as intravenous injection group with cephradine, 3) 35 cases as control group are neither irrigated nor injected. Febrile morbidity was also evaluated by means of a fever index. The incidence of clinically diagnosed endometritis in the three group were 6.7%, 2.9%, and 22.9%. As these results, two study groups were markedly reduced the incidence of endometritis than control group. There was no significant difference between the intrauterine irrigation with cephradine and control, but significant difference between the intravenous cephradine injection and control (P<0.05). With the results of fever index analysis, both prophylactic intrauterine irrigation and intravenous injection markedly reduce the incidence of endometritis after cesarean section with statistical significance (P<0.05), and also markedly reduce the febrile degree.
Anti-Bacterial Agents ; Cephradine* ; Cesarean Section* ; Endometritis ; Female ; Fever ; Humans ; Incidence ; Injections, Intravenous* ; Pregnancy

Nonsteroidal anti-inflammatory drugs (NSAIDs) have analgesic, antipyretic, and anti-inflammatory properties and are widely used for treating musculoskeletal and cardiovascular diseases. Notwithstanding these therapeutic efficacies, gastrointestinal toxicity is the major health problem associated with NSAID use. NSAID-related peptic ulcers are a well-known complication due to direct mucosal injury and cyclooxygenase inhibition. Risk factors for NSAID-related peptic ulcers include a prior history of peptic ulcer; age > 65 years; high-dose NSAID therapy; and concurrent use of aspirin (including low dose), corticosteroids, or anticoagulants. In addition, Helicobacter pylori infection is an independent risk factor; therefore, eradication therapy is recommended in high-risk patients using NSAIDs. Currently, misoprostol, H2-receptor antagonists, proton pump inhibitors, and COX-2 selective inhibitors are used to prevent and treat NSAID-related peptic ulcers. Further, strategic approaches are required through appropriate NSAID use and risk factor stratification to prevent NSAID-related peptic ulcers and associated complications.
Adrenal Cortex Hormones ; Anti-Inflammatory Agents, Non-Steroidal* ; Anticoagulants ; Aspirin ; Cardiovascular Diseases ; Helicobacter pylori ; Humans ; Misoprostol ; Peptic Ulcer* ; Prostaglandin-Endoperoxide Synthases ; Proton Pump Inhibitors ; Risk Factors

Recently, we found an ectopic paragoniums westermani in the scrotum from 19 years old male patient who admitted our hospital under the impression of scrotal mass. We report this case, and literatures were reviewed briefly.
Humans ; Male ; Paragonimiasis* ; Scrotum ; Young Adult

No abstract available.
Muscle, Skeletal* ; Tibial Nerve*

The purposes of this study were to investigate the satisfaction of use of removable denture elated to general, functional and esthetic factors among dental patients in national sorokdo hospital, and to establish the structure relationships of dental treatment satisfaction. Two hundred fifty hansen`s patients who consented with this survey were selected and examined their oral status. Satisfaction degree was estimated by means of self-developed questionarires, filled out by face-to-face interview. Collected data were analyzed by t-tast The obtained results were as follow : 1. The satisfaction degree of four subscales was highest in esthetic actor (3.17+/-0.36), denture retention factor(3.10+/-0.60), general treatment satisfaction factor(2.94+/-0.56), and masticatory function factor (2.90+/-0.68) in descending order. It was appeared that patients was generally satisfied with all four factor. 2. On the comparison between proportion of denture satisfaction and satisfactio 02n of subscales, as the satisfaction of general treatment, masticatory function and denture retention were increased, the proportion of denture satisfaction of esthetic function and proportion of denture satisfaction. 3. The masticatiory function factor, denture retention factor and genernal satisfaction of treatment factor were directly affected on the denture satisfaction, but esthetic factor was affected indirectly on the denture satisfaction as a result of path analysis
Dental Prosthesis* ; Denture Retention ; Dentures ; Humans