2.Analysis of thromboembolic events in head and neck cancer patients who underwent concurrent chemoradiotherapy with cisplatin
Hundo CHO ; Jin-Hyuk CHOI ; Seok Yun KANG ; Hyun Woo LEE ; Yong Won CHOI ; Tae-Hwan KIM ; Mi Sun AHN ; Chul-Ho KIM ; Yoo Seob SHIN ; Jeon Yeob JANG ; Young-Taek OH ; Jaesung HEO ; Seung Soo SHEEN
The Korean Journal of Internal Medicine 2022;37(6):1269-
3.Analysis of thromboembolic events in head and neck cancer patients who underwent concurrent chemoradiotherapy with cisplatin
Hundo CHO ; Jin-Hyuk CHOI ; Seok Yun KANG ; Hyun Woo LEE ; Yong Won CHOI ; Tae-Hwan KIM ; Mi Sun AHN ; Chul-Ho KIM ; Yoo Seob SHIN ; Jeon Yeob JANG ; Young-Taek OH ; Jaesung HEO ; Seung Soo SHEEN
The Korean Journal of Internal Medicine 2022;37(3):653-659
Background/Aims:
The study investigated the incidence of thromboembolic events (TEE) in head and neck (H&N) cancer patients who received concurrent chemoradiotherapy (CCRT) with cisplatin, and analyzed the factors affecting TEE occurrence
Methods:
Two hundred and fifty-seven patients who started CCRT with cisplatin for H&N cancer from January 2005 to December 2019 were analyzed.
Results:
TEE occurred in five patients, an incidence rate of 1.9%. The 2-, 4-, and 6-month cumulative incidences of TEE were 0.8%, 1.6%, and 1.9%, respectively. Khorana score was the only factor associated with TEE occurrence (p = 0.010).
Conclusions
The incidence of TEE in H&N cancer patients who underwent CCRT with cisplatin was relatively low when compared to other types of cancer. However, patients with a high Khorana score require more careful surveillance for possible TEE occurrence.