1.Poor Dietary Protein Intake in Elderly Population with Sarcopenia and Osteosarcopenia: A Nationwide Population-Based Study
Jun-Il YOO ; Kyung-Hag LEE ; Yonghwan CHOI ; Jaehwang LEE ; Yong-Geun PARK
Journal of Bone Metabolism 2020;27(4):301-310
Background:
Our purpose in this study was to evaluate any deficiency of protein intake for different types of sarcopenia, including osteosarcopenia and sarcopenic obesity and to establish a cut-off value for the relationship between malnutrition, sarcopenia, and osteosarcopenia.
Methods:
The cross-sectional study was performed using data from the Korea National Health and Nutrition Examination Survey. A total of 4,020 participants (men, 1,698 and women, 2,322) were analyzed in the present study. Sarcopenia is defined according to the criteria for the Asia Working Group for Sarcopenia. To evaluate the adequacy of protein intake, the value obtained by dividing the amount of protein consumed through food by the daily recommended protein amount (50 g/day) of Korean males was defined as the nutrient intake ratio.
Results:
Total protein (P<0.001 in men, P<0.001 in women) and low dietary intake protein (P<0.001 in men, P=0.046 in women) were significantly lower in the sarcopenia group than in the normal group, and were significantly lower in the osteosarcopenia group than in the normal group for both men and women. The cut-off value of the adjusted weight of protein intake for sarcopenia was 0.58 g/kg/day in men and 0.98 g/kg/day in women. The cut-off value for adjusted weight of protein intake for osteo-sarcopenia was 0.8 g/kg/day in men and 0.5 g/kg/day in women.
Conclusions
A comprehensive dietary assessment to detect nutritional deficits that predispose one to or aggravate muscle atrophy is important for establishing a treatment plan for patients with malnutrition.
2.Risk Factors of Acute Renal Failure after Colorectal Surgery.
Hae Mi LEE ; Chang Jae HWANG ; Jaehwang KIM ; Heung Dae KIM ; Dae Pal PARK ; Il Suk SEO ; Sun Ok SONG ; Sae Yeon KIM ; Deuk Hee LEE ; Daelim JEE
Yeungnam University Journal of Medicine 2007;24(2):275-286
BACKGROUND: Acute renal failure is one of the leading causes of postoperative morbidity and mortality. The purpose of this study was to determine the risk factors that are associated with acute renal failure after colorectal surgery. MATERIALS AND METHODS: Five hundred seventy patients who operated colorectal surgery at the Yeungnam University Medical Center over three years from 2004 to 2006 were enrolled in this study. The effects of gender, age, ASA classification, concomitant disease, surgery type and duration, reoperation, urogenital manipulation, medication, hypotension, hypovolemia, transfusion, and postoperative ventilatory care on the occurrence of acute renal failure after colorectal surgery were studied. RESULTS: The major risk factors of acute renal failure after colorectal surgery were age of patients (P=0.003), ASA classification (P<0.001), concomitant disease (P<0.001), duration of the time surgery (P=0.034), reoperation (P=0.001), use of intraoperative diuretics (P=0.005), use of postoperative diuretics (P<0.001), intraoperative hypotension (P=0.018), intraoperative transfusion (P<0.001), postoperative transfusion (P<0.001), and postoperative ventilatory care (P=0.001). CONCLUSION: Multiple factors cause synergistic effects on the development of acute renal failure after colorectal surgery. Therefore, efforts to reduce the risk factors associated with acute renal failure are needed. In addition, intensive postoperative care should be provided to all patients.
Academic Medical Centers
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Acute Kidney Injury*
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Classification
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Colorectal Surgery*
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Diuretics
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Humans
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Hypotension
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Hypovolemia
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Mortality
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Postoperative Care
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Reoperation
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Risk Factors*
3.Hypersensitivity myocarditis confirmed by cardiac magnetic resonance imaging and endomyocardial biopsy.
Yumi PARK ; Sung Gyun AHN ; Anna KO ; Sang Ho RA ; Jaehwang CHA ; Yong Gwan JEE ; Ji Hyun LEE
The Korean Journal of Internal Medicine 2014;29(2):236-240
Myocarditis often occurs due to viral infections and postviral immune-mediated responses. Hypersensitivity myocarditis is a rare form of myocarditis. Numerous drugs can induce myocarditis, which is typically reversible after withdrawal of the causative agent. Here, we report a case of hypersensitivity myocarditis that was probably triggered by amoxicillin and that resolved completely with heart failure management as well as discontinuation of the drug. A 68-year-old woman presented with acute chest pain mimicking acute coronary syndromes, but the coronary angiography was normal. A recent history of taking medications, skin rash, and peripheral eosinophilia suggested a diagnosis of hypersensitivity myocarditis, which was confirmed by cardiac magnetic resonance imaging and endomyocardial biopsy.
Aged
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Amoxicillin/*adverse effects
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Anti-Bacterial Agents/*adverse effects
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*Biopsy
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Drug Hypersensitivity/*diagnosis/drug therapy/etiology/pathology
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Electrocardiography
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Female
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Glucocorticoids/therapeutic use
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Humans
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*Magnetic Resonance Imaging
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Myocarditis/chemically induced/*diagnosis/drug therapy/pathology
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Myocardium/*pathology
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Predictive Value of Tests
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Prednisolone/therapeutic use
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Risk Factors
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Treatment Outcome