1.Tre atment of Gonorrhoea with Antibiotic Combinations : Kanamycin plus Ampicillin / Probenecid versus Kanamycin plus Talampicillin / Probenecid.
Chang Hoon KWAK ; Jae Hong KIM ; Joong Hwan KIM
Korean Journal of Dermatology 1985;23(6):745-751
riie snbjects werc 269 patients with uncomplicated gonococcal urethritis, who visited the Veiereal Disease Clinic of Choong-Ku Public Health Center in Fieoul from August to Decernber 1984. ()ni hundred and four of 108 patients treated with 1.anamycin, 2 gm, IM plus anipi illin,3.5 gm, p0 plus probenecid, 1 gm, PO regirrien recovered with 65(62. 5 post-gonococcal urethritis(PGlJ) and 4(3.7%) failed, One hundred and seven of III patients treated with kanamycin, 2 gm, IM plus talarnpicillin, 2 gm, PO plus probenecid, 1 gm, po regimen recovered with 71 (66. 4% ) post-goriococcal urethritis and 4(3. 6%) failed. It is suggeste,d that both these antibiotic comlbination regimens have similarly good effect in the treatment. of gonococcal urethritis.
Ampicillin*
;
Humans
;
Kanamycin*
;
Probenecid*
;
Public Health
;
Talampicillin*
;
Urethritis
2.Endoscopic Variceal Ligation for Treatment of Bleeding Esophageal Varices.
Jae Dong LEE ; Jun Hwan CHO ; Sung Jin KWAK
Korean Journal of Gastrointestinal Endoscopy 1994;14(4):397-401
The endoscopic variceal ligation(EVL) has been adopted as a new treatment for acute hemorrhage from esophageal varices that ranks the highest mortality rate in upper gastrointestinal tract bleedings. This treatment method has good effects for the urgent treatment and eradication of varices from acute variceal bleeding in repeated sessions. We enrolled 34 patients with an acute or chronic variceal bleeding episode at the time of admission in this study from Apr. 8, 1992 to June. 2, 1994. Among 34 patients, there were 31 males and 3 females, at ages between 45-66(mean: 52 years). The incidence of symptoms on admission was 10 in tarry stool, 9 in hematemesis 8 in ascites, 4 in hepatic encephalopathy and 3 in nonspecific symptoms. Varices were eradicated or reduced to grade I in 30(88.2%) of the 34 patients by 4-25 bands (mean: 10.8 bands) in 1-7 EVL sessions(mean: 3.1 sessions). After EVL, there are complicated by active bleeding in 3 patients, dysphagia in 3 patienta and transient chest discomfort in 5 patients but subsided during 24 hours. These results indicated that EVL is a safe method for treatment of bleeding from esophageal varices.
Ascites
;
Deglutition Disorders
;
Esophageal and Gastric Varices*
;
Female
;
Hematemesis
;
Hemorrhage*
;
Hepatic Encephalopathy
;
Humans
;
Incidence
;
Ligation*
;
Male
;
Mortality
;
Thorax
;
Upper Gastrointestinal Tract
;
Varicose Veins
3.Comparison of the Effect of Cefadroxil and Kanamycin Sulfate in the Treatment of Male Gonorrhoea.
Chang Hoon KWAK ; Young Suck RO ; Young Tae KIM ; Jae Hong KIM ; Joong Hwan KIM
Korean Journal of Dermatology 1984;22(6):599-603
No abstract available.
Cefadroxil*
;
Humans
;
Kanamycin*
;
Male*
4.Abnormal Brain CT Findings of Tuberous Sclerosis.
Young Suck RO ; Chang Hoon KWAK ; Jae Hong KIM ; Joong Hwan KIM ; Gi Chul HAN
Korean Journal of Dermatology 1985;23(1):77-82
The lesions of central nervous system in tuberous sclerosis often calcify, especially those present in the perivascular region, allowing the computed tomography to make early and definite diagnosis, even when patients intelligence was normal, seizures were absent, or clinical findings were not specific, We report three cases of tuberous sclerosis, which showed pathognomic subependymal paraventricular calcification in brain CT.
Brain*
;
Central Nervous System
;
Diagnosis
;
Humans
;
Intelligence
;
Seizures
;
Tuberous Sclerosis*
5.Clinical study on lupus nephritis.
Won KIM ; Jae Young KWAK ; Chang Hwan LEE ; Sung Kwang PARK ; Sung Kyew KANG
Korean Journal of Nephrology 1993;12(4):588-597
No abstract available.
Lupus Nephritis*
6.The Effect of Oral Ketoconazole in Dermatophytosis.
Jahng Won JUNN ; Do Hun HWANG ; Chang Hoon KWAK ; Jae Hong KIM ; Joong Hwan KIM
Korean Journal of Dermatology 1984;22(1):16-21
Seventeen volunteers with cutaneous dermatophytosis were enrolled in a clinical trial to evaluate the effectiveness of oral ketoconazole. The group included six patients with tinea cruris(6 malcs), four with tinea corporis, including one with tinea faciai, (3 males, 1 female), three with tinea versicolor(3 males) and four with tinea capitis(3 males, 1 female). The oral ketoconazole was taken within 10 minutes after a meal. The patients under the age of 10 received 100mg of ketoconazole per day, whereas those aged over 11 received 200mg of ketoconazole until the skin lesions are cured. Seventeen patients had complete clinical and mycologic cure, one responded clinically. It required one to four weeks to become culturally negative for tinea cruris, four to seven weeks for tinea corporis, three to eight weeks for tinea capitis. For tinea versicolor it required three to five weeks to become negative by scotch tape method. Adverse reactions to ketoconazole were absent and no patients required discontinuation of the drug. The results indicate that ketoconazole is a safe and effective drug for the treatment of dermatophytosis.
Humans
;
Ketoconazole*
;
Male
;
Meals
;
Skin
;
Tinea Capitis
;
Tinea Versicolor
;
Tinea*
;
Volunteers
7.Epidemiology of hip fractures.
Hyoun Oh CHO ; Kyoung Duck KWAK ; Sung Do CHO ; Jung Hwan SUH ; Bub Jae LEE
The Journal of the Korean Orthopaedic Association 1993;28(3):1153-1159
No abstract available.
Epidemiology*
;
Hip Fractures*
;
Hip*
8.A Study on the Possibility of Endoscopic Modified Lothrop Procedure Using Imaging Measurements
Hyung-Bon KOO ; Jae-Hwan KWAK ; Jae-Hoon LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 2024;67(5):277-282
Background and Objectives:
Endoscopic modified Lothrop procedure (EMLP) is indicated after the failure of standard endoscopic sinus surgery techniques to alleviate frontal sinus disease. Three parameters, such as nasal beak thickness (NBT), accessible dimension of frontal recess (AD), and distance of frontal sinus (DFS), are important in the preoperative evaluation and selection of patients for EMLP. The purpose of this study is to apply the parameters to determine the feasibility of EMLP for the Korean population.Subjects and Method Sinus CT was performed on a total of 233 people, and a study was conducted using 466 bilateral sides with the following parameters: 1) NBT 2) the distance from the posterior margin of nasal beak to the anterior margin of skull base (DNBSB) 3) the right and left AD and 4) the right and left DFS. If the values of NBT, AD, and DFS of the study group were less than 10 mm, greater than 5 mm and 7 mm, respectively, they were considered candidates for the EMLP.
Results:
DNBSB, NBT, AD, and DFS were 6.97±1.96 mm, 7.01±1.58 mm, 7.16±2.40 mm, and 9.47±2.91 mm, respectively. Parameters except DNBSB showed significant differences in male and female. The feasibility of EMLP was 75.36% for male and 57.89% for female, with 68.24% overall.
Conclusion
The overall feasibility of EMLP was 68.24% for the study group, where feasibility was lower for female than for male.
9.Clinical Observation on Antihypertensive Effects of Enalapril.
Choong Hwan KWAK ; Jin Hong CHUNG ; Hyoung Woo LEE ; Shung Chull CHAE ; Jae Eun JUN ; Wee Hyun PARK
Korean Circulation Journal 1989;19(1):97-103
To observe the antihypertensive effects of the angiotensin-converting enzyme inhibitor, enalapril, a daily average dosage of 20mg was administred to 38 patients with essential hypertension for 4 weeks. Changes in blood pressure and heart rate, and the frequencies of adverse reactions during the drug administration were constantly observed. At the end of the 4th week of administration the mean diastolic blood pressure decreased from 104+/-11.3 to 91+/-7.9mmHg(<0.001), and the mean systolic blood pressure from 165+/-16.8 to 142+/-10.6mmHg(P<0.001), An effective antihypertensive action of enalapril was observed in 31 out of 38 cases(82%), and normalization of diastolic blood pressure below 85mmHg was shown in 27 cases(71%). The most remarkable antihypertensive effects were shown at the end of first week, and the effect increased progressively until the end of 4th week of therapy. There were no significant changes in heart rate during the observation period. Adverse reactions occured in only 7 cases(18%). These reactions included headache, dizziness, fatigue, skin rash and facial flushing in the order of frequency. Almost all of these reaction were mild and transient, disappearing spontanously without discontinuation of the medication. In conclusion, enalapril seems to be a safe and effective primary antihypertensive drug for the treatment of essential hypertension.
Blood Pressure
;
Dizziness
;
Enalapril*
;
Exanthema
;
Fatigue
;
Flushing
;
Headache
;
Heart Rate
;
Humans
;
Hypertension
10.Total Elbow Arthroplasty: Clinical Outcomes, Complications, and Revision Surgery
Jae Man KWAK ; Kyoung Hwan KOH ; In Ho JEON
Clinics in Orthopedic Surgery 2019;11(4):369-379
Total elbow arthroplasty is a common surgical procedure used in the management of advanced rheumatoid arthritis, posttraumatic arthritis, osteoarthritis, and unfixable fracture in elderly patients. Total elbow prostheses have evolved over the years and now include the linked, unlinked, and convertible types. However, long-term complications, including infection, aseptic loosening, instability, and periprosthetic fracture, remain a challenge. Here, we introduce each type of implant and evaluate clinical outcomes and complications by reviewing the previous literature.
Aged
;
Arthritis
;
Arthritis, Rheumatoid
;
Arthroplasty
;
Elbow Prosthesis
;
Elbow
;
Humans
;
Osteoarthritis
;
Periprosthetic Fractures
;
Reoperation
;
Treatment Outcome