1.Intrahepatic Arterioportal Shunt:A Mechanism of Hypovascular Hepatocellular Carcinoma.
Journal of the Korean Radiological Society 1995;33(2):259-264
PURPOSE: To prove whether the arterioportal shunt, especially transvasal shunt is one of the cause of the hypovascular hepatocellular carcinoma. MATERIALS AND METHODS: We evaluated the early phase images of table incremental dynamic CT and hepatic angiography in 20 cases of hepatoceltular carcinomas with transvasal arterioportal shunt. RESULTS: In hepatic arteriography, 18 cases were hypovascular and the remained 2 cases showed hypervascular tumor staining than surrounding normal hepatic parenchyme. In the early phase dynamic CT, 18 cases were hypodense(including 4 cases of focal hyperdensity in hypodense background), one was isodense and remaining one was hyperdense. CONCLUSION: Arterioportal shunt, especially transvasal shunt may make originally hypervasular hepato-cellular carcinoma to hypovascular lesion in the early phase dynamic CT or hepatic arteriography. In attempt to differentiate hepatic masses by tumor vascularity in recently widely used table incremental dynamic CT, the vascular patterns of the mass should be considered by close evaluation of vascular pattern of the liver, such as morphology of perfusion abnormality and arterioportal shunt, etc.
Angiography
;
Carcinoma, Hepatocellular*
;
Liver
;
Perfusion
2.Focal Nodular Hyperplasis in Liver.
Ki Ho SEONG ; Jae Ho CHO ; Jae Chun CHANG
Yeungnam University Journal of Medicine 1995;12(2):400-404
Focal nodular hyperplasia is a benign hepatic tumor mainly composed of nodules of hepatocytes and Kupffer cells separated by fibrous septa. In general, it is difficult to differentiate focal nodular hyperplasia and hepatocellular carcinoma on ultrasonography, conventional CT(computerized tomography), and angiography. But IV bolus CT is of particular value in the diagnosis of focal nodular hyperplasia because it can divide enhanced CT into early and late phase and can characterize tumor vascularity and analyze any intratumoral elements. In our case, it was seen as a hypoechoic mass lesion on ultrasonograpl'hy and hyperdense mass lesion on early-phase IV bolus CF and isodense mass, lesion on late-phase IV bolus CT. On angiography, hypertrophy of the feeding artery and tumor staining were well visualized. The patient underwent operation and the mass was pathologically confirmed to a focal nodular hyperplasia. We report the first case of focal nodular hyperplasia on IV bolus CT in Korea.
Angiography
;
Arteries
;
Carcinoma, Hepatocellular
;
Diagnosis
;
Focal Nodular Hyperplasia
;
Hepatocytes
;
Humans
;
Hypertrophy
;
Korea
;
Kupffer Cells
;
Liver*
;
Ultrasonography
3.Antiproliferative effect of difluoromethylornithine on human gastric and colorectal cancer cell lines in serum containing media.
Journal of the Korean Cancer Association 1992;24(3):359-364
No abstract available.
Cell Line*
;
Colorectal Neoplasms*
;
Eflornithine*
;
Humans*
4.Advantades of the intravenous bolus CT scan in differentiation of hepatic masses.
Jae Ho CHO ; Jae Chun CHANG ; Bok Hwan PARK
Journal of the Korean Radiological Society 1992;28(6):942-950
We performed IV bolus CT scan in 40 patients with final diagnosis of various hepatic masses in order to evaluate hemodynamic changes and differentiating characters of the lesions. Preenhanced, early and late phase post enhanced, and delayed CT scans were obtained with rapid IV bolus injection of contrast materials and table sliding method for pertinent scans. In hepatomas, early enhanced CT scan directly showed hypervascular change and active viable portion of the mass and late phase CT scan showed capsular enhancement. In addition, extracapsular invasion and post-embolization recurrence were more easily visualized. In hemangiomas, early and late enhancing types could be categorized according to the time of maximal enhancement. In metastatic liver malignancies and cholangiocarcinomas, specific findings were seen in early phase and delayed CT scans and not in conventional CT scan. In conclusion, IV bolus CT scan is a very useful CT method in demonstrating the characteristic hemodynamic patterns and in differential diagnosis of the hepatic masses.
Carcinoma, Hepatocellular
;
Cholangiocarcinoma
;
Contrast Media
;
Diagnosis
;
Diagnosis, Differential
;
Hemangioma
;
Hemodynamics
;
Humans
;
Liver
;
Methods
;
Recurrence
;
Tomography, X-Ray Computed*
5.IV bolus CT findings of the tuberculous granuloma: A case report.
Jae Ho CHO ; Jae Chun JANG ; Bok Hwan PARK
Journal of the Korean Radiological Society 1993;29(1):147-151
Isolated heaptic tuberculous granuloma with no coexistent tuberculosis elsewhere in the body is extremely rare. We report a case of pathologically proven tuberculous granuloma in the liver followed with both IV bolus and portal CT scans. The lesion on preenhanced CT scan showed undefinable isodensity. After IV bolus injection, it showed poor enhancement with central low-density and surrounding hyperdenity due to compensatory hypervascularity of the left lobe of liver in early phase. It showed peripheral rim enhancement in late phase and in delayed phase showed relatively homogeneous but slightly decreased contract enhancement. On portal CT scan, it showed a hypodense portal defect similar to other hepatic mass lesions. During follow-up studies, it was a slowly growing mass which was more easily detectable by prtal CT scans than bolus CT scans.
Follow-Up Studies
;
Granuloma*
;
Liver
;
Tomography, X-Ray Computed
;
Tuberculosis
6.CT findings of Desmoid tumor arising at Abdominai Wall.
Dae Hyoun CHO ; Jae Ho CHO ; Jae Chun CHANG
Yeungnam University Journal of Medicine 1995;12(2):386-392
Desmoid tumor is a type of fibromatosis usually arise in deep musculo-aponeurotic structures, primarily of the trunk and extremities. It is characterized by proliferation of fibroblastic tissue and does not metastasize but may be locally aggressive. Eventhough the surgical margin reveals clean, recurrence often occurs. To analyze the extent of the tumor and homodynamic characteristics exactly, we performed IV bolus CT. Desmoid tumors show peripheral rim enhancement on early phase scan and more strong, central enhancement on late phase IV bolus CT, which reflects abundant fibroblastic components of the tumor. We report two cases of pathologically confirmed desmoid tumor performed IV bolus CT.
Abdominal Wall
;
Extremities
;
Fibroblasts
;
Fibroma
;
Fibromatosis, Aggressive*
;
Recurrence
7.Advantages of incremental dynamic CT in the evaluation of pancreatic and peripancreatic lesions.
Jae Chun CHANG ; Jae Ho CHO ; Bok Hwan PARK
Journal of the Korean Radiological Society 1993;29(4):787-793
Authors compared early phase scan of the IV bolus CT (two phase incremental bolus dynamic CT) with late enhanecd scan similar to the conventional contrast enhanced CT for evaluation of the advantages of the IV bolus CT with two viewpoints of the pancreatic or peripancreatic mass and peripancreatic lymphadenopathy in 68 patients-28 cases of the pancreatic cancer, 6 cases of the pancreatitis and 34 cases of the pancreatic or peripancreatic metastasis. On the diagnosis of the pancreatic or peripancreatic mass, IV bolus CT could show the lesion(s) more easily in 41% (Grade II; 13/31) and much more easily in 34% (Grade III; 10/31) when compared with conventional contrast CT scan. The diagnosis of the peripancreatic lymph node involvement was also easy in 51%(Grade II; 20/39) and much easier in 37% (Grade III; 14/39). We thought that these differences were originated from the increase of the contrast between the lesion and normal portion because the early enhanced scans reflected the active blood flow change more exactly. Therefore IV bolus CT had advantages in comparison with the conventional drip infusion contrast CT in the diagnosis of the presence and pathologic extension of the pancreatic and peripancreatic lesion.
Diagnosis
;
Infusions, Intravenous
;
Lymph Nodes
;
Lymphatic Diseases
;
Neoplasm Metastasis
;
Pancreatic Neoplasms
;
Pancreatitis
;
Tomography, X-Ray Computed
8.Advantages of incremental dynamic CT in the evaluation of pancreatic and peripancreatic lesions.
Jae Chun CHANG ; Jae Ho CHO ; Bok Hwan PARK
Journal of the Korean Radiological Society 1993;29(4):787-793
Authors compared early phase scan of the IV bolus CT (two phase incremental bolus dynamic CT) with late enhanecd scan similar to the conventional contrast enhanced CT for evaluation of the advantages of the IV bolus CT with two viewpoints of the pancreatic or peripancreatic mass and peripancreatic lymphadenopathy in 68 patients-28 cases of the pancreatic cancer, 6 cases of the pancreatitis and 34 cases of the pancreatic or peripancreatic metastasis. On the diagnosis of the pancreatic or peripancreatic mass, IV bolus CT could show the lesion(s) more easily in 41% (Grade II; 13/31) and much more easily in 34% (Grade III; 10/31) when compared with conventional contrast CT scan. The diagnosis of the peripancreatic lymph node involvement was also easy in 51%(Grade II; 20/39) and much easier in 37% (Grade III; 14/39). We thought that these differences were originated from the increase of the contrast between the lesion and normal portion because the early enhanced scans reflected the active blood flow change more exactly. Therefore IV bolus CT had advantages in comparison with the conventional drip infusion contrast CT in the diagnosis of the presence and pathologic extension of the pancreatic and peripancreatic lesion.
Diagnosis
;
Infusions, Intravenous
;
Lymph Nodes
;
Lymphatic Diseases
;
Neoplasm Metastasis
;
Pancreatic Neoplasms
;
Pancreatitis
;
Tomography, X-Ray Computed
9.Foregut Cyst Communicated with Esophagus, Lined by Bronchial Mucosa.
Jae Chun CHANG ; Kil Ho JHO ; Mi Soo HWANG
Yeungnam University Journal of Medicine 1984;1(1):139-144
A case of foregut cyst communicated with esophagus and lined by bronchial mucosa is reviewed and its embryologic base of maldevelopment it discussed. It is not always easy to distinguish between digestive and respiratory cyst in mediastinum. There is whole range of intermediate between a cyst with ciliated and one with squamous or columnar mucosa. Origin of this dysembryoplasia is difficult to determine when on consider that the esophagus is covered with ciliated epithelium until the eleventh week of fetal life and that ciliated growth are found on its wall until the sixth month of the fetal life. And we concluded, general agreement is that cysts which have gastric epithelium in whole or in part, represent a distinct type and should be classified as (gastro) enteric cyst, mediastinal cyst containing cartilage were considered definitely as respiratory (bronchial or bronchogenic) cyst.
Cartilage
;
Epithelium
;
Esophagus*
;
Mediastinal Cyst
;
Mediastinum
;
Mucous Membrane*
10.Significance of the AFP Level and HBsAg in Differentiation of Hepatic Masses.
Jae Woon KIM ; Won Kyu PARK ; Jae Ho CHO ; Jae Chun CHANG ; Bok Hwan PARK
Yeungnam University Journal of Medicine 1996;13(2):302-307
Hepatic masses show different enhancing patterns in N bolus computed tomography: Hepatocellular carcinoma shows high-attenuation in the early enhancing phase and low-attenuation in the late enhancing phase, hemangioma shows peripheral dot-like high-attenuation in the early enhancing phase and central high-attenuation in the late enhancing phase, and metastatic cancer and cholangiocelluar carcinoma show peripheral high-attenuation rim in the early enhancing phase and central portion gradulally high attenuation in the late enhancing phase. but sometimes enhancing patterns of the hepatic masses are confuse. To evaluate the significance of the AFP level and HBsAg in differentiation of the hepatic masses, we retrospectively analyzed AFP level and HBsAg' in 228 pathologically or radiologically confirmed hepatocellular carcinomas, and 137 pathologically nonhepatocellular cacinomas. The results were as follows In hepatocellular carcinoma, AFP level above 20ng/ml was 77.8% and HBsAg positve was 72.6%. In nonhepatocellular carcinoma, AFP level above 20ng/ml was 3.7% and HBsAg positve was 16.1%. We concluded that AFP level and HBsAg are helpful to distinguish hepatocellular carcinoma from nonhepatocellular carcinoma, when IV bolus computed tomogram finding is uncertain.
Carcinoma, Hepatocellular
;
Hemangioma
;
Hepatitis B Surface Antigens*
;
Retrospective Studies