1.Measurement and Analysis of Neurosensory Retinal Detachment in Central Serous Chorioretinopathy Using Heidelberg Retina Tomograph.
Jae Yong HEO ; No Hoon KWAK ; Jin Seong YOO
Journal of the Korean Ophthalmological Society 2000;41(12):2585-2590
No Abstract Available.
Central Serous Chorioretinopathy*
;
Retina*
;
Retinal Detachment*
;
Retinaldehyde*
2.A case of parenchymal consolidative lesions with air-bronchogram in chest CT scan.
Jae Yong KWAK ; Jae Seok SEO ; Yong Chul LEE ; Yang Keun RHEE
Tuberculosis and Respiratory Diseases 1993;40(2):203-207
No abstract available.
Thorax*
;
Tomography, X-Ray Computed*
3.The effect of intravenous ritodrine hydrochloride on premature labor.
Jae Min LEE ; Yong Ho MOON ; Sun Jae HWANG ; Kyoung Hoon LEE ; Tae Ro KWAK
Korean Journal of Obstetrics and Gynecology 1993;36(7):3010-3016
No abstract available.
Female
;
Obstetric Labor, Premature*
;
Pregnancy
;
Ritodrine*
4.Malignant Pericardial Effusion Incidentally Detected by Tc-99m MDP Bone Scintigraphy.
Seok Tae LIM ; Myung Hee SOHN ; Jae Yong KWAK ; Chang Yeol YIM
Korean Journal of Nuclear Medicine 2001;35(4):291-292
No abstract available.
Pericardial Effusion*
;
Radionuclide Imaging*
;
Technetium Tc 99m Medronate*
5.Treatment of Diffuse Large B Cell Lymphoma.
The Korean Journal of Internal Medicine 2012;27(4):369-377
Diffuse large B cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma in all countries and all age groups. DLBCL is potentially curable, and the outcome of patients with DLBCL has completely changed with the introduction of therapy involving the monoclonal antibody rituximab in combination with chemotherapy. Nonetheless, relapse is detected after treatment with rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisolone in approximately 30% of patients. It has recently become clear that DLBCL represents a heterogeneous admixture of quite different entities. Gene expression profiling has uncovered DLBCL subtypes that have distinct clinical behaviors and prognoses; however, incorporation of this information into treatment algorithms awaits further investigation. Future approaches to DLBCL treatment will use this new genetic information to identify potential biomarkers for prognosis and targets for treatment.
Algorithms
;
Antibodies, Monoclonal, Murine-Derived/therapeutic use
;
Antineoplastic Combined Chemotherapy Protocols/therapeutic use
;
Gene Expression Profiling
;
Humans
;
Lymphoma, Large B-Cell, Diffuse/classification/genetics/*therapy
;
Salvage Therapy
;
Stem Cell Transplantation
6.A clinical study of the osteoradionecrosis of the jaw.
Yong Kack KIM ; Heon Seok YU ; Jae Keun KWAK ; Kyu Yeong KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(2):177-184
No abstract available.
Jaw*
;
Osteoradionecrosis*
7.A clinical study of the osteoradionecrosis of the jaw.
Yong Kack KIM ; Heon Seok YU ; Jae Keun KWAK ; Kyu Yeong KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(2):177-184
No abstract available.
Jaw*
;
Osteoradionecrosis*
8.Activation of the Cardiac ATP-Sensitive K+Channel by KR-30816,Newly Synthesized Potassium Channel Opener.
Kyoung Suk RHEE ; Jae Ki KO ; Yong Geun KWAK ; Soo Wan CHAE
Korean Circulation Journal 1994;24(6):889-898
BACKGROUND: The effects of a newly synthesized potassium channel opener, KR-30816((-)(nitro-2-hydroxymethyl-2-methy-2H-1-benzopyran-4-y1)pyridine oxide) on the action potential of papillary muscles of guinea pigs and the ATP-sensitive potassium channel current(IKATP) of single ventricular muscle cells of rats were examined to make clear its action mechanism of the KATPchannel. METHODS: We used the conventional microelectrode and the excised inside-out patch configuration. RESULTS: KR-30816 caused a shortening of the action potential duration in dose-dependent manner, which was inhibited by glibenclamide(3microM). Before run-down of the K+channel, KR-30816 activated the cardiac ATP-sensitive K+ channel only in the presence of ATP and shifted the dose-response relation curve between [ATP]i and the channel activity to the right in parallel. After run-down of the KATP channel, KR-30816 did not after the channel opening either in the absence or in the presence of UDP. CONCLUSION: These results suggest that KR-30816 antagonizes the inhibitory effect of ATP on the KATPchannel in a competitive manner, thereby enhancing the channel openings.
Action Potentials
;
Adenosine Triphosphate
;
Animals
;
Guinea Pigs
;
Heart
;
Microelectrodes
;
Muscle Cells
;
Papillary Muscles
;
Potassium Channels*
;
Potassium*
;
Rats
;
Uridine Diphosphate
9.Technetium-99m MDP bone scintigraphic findings of hypercalcemia in accelerated phase of chronic myelogenous leukemia.
Hyo Sung KWAK ; Myoung Hee SOHN ; Seok Tae LIM ; Jae Yong KWAK ; Chang Yeol YIM
Journal of Korean Medical Science 2000;15(5):598-600
Hypercalcemia in accelerated phase of chronic myelogenous leukemia (CML) is very rare. Its pathogenesis is considered humoral hypercalcemia of malignancies mediated by parathyroid hormone-related protein (PTHrP). In severe hypercalcemia, calcifications in kidneys, skin, vessels, heart, and stomach may occur. Our two cases were admitted because of severe hypercalcemia in accelerated phase of CML. On Tc-99m methylene diphosphonate (MDP) bone scintigraphies, a marked tracer accumulation was seen in the lung, heart, stomach and kidney. We report increased tracer accumulation of multiple organs on Tc-99m MDP bone scintigraphy in two rare hypercalcemic patients with CML.
Adult
;
Bone Diseases/radionuclide imaging*
;
Bone Diseases/etiology*
;
Calcinosis/radionuclide imaging
;
Calcinosis/etiology
;
Case Report
;
Human
;
Hypercalcemia/radionuclide imaging*
;
Hypercalcemia/etiology*
;
Leukemia, Myeloid, Chronic/metabolism
;
Leukemia, Myeloid, Chronic/complications*
;
Male
;
Middle Age
;
Proteins/metabolism
;
Technetium/diagnostic use
10.Multiple Myeloma Manifestated by Necrotizing Fasciitis.
Jae Sung PARK ; Yong Keun CHO ; Myeong Sin MA ; Jae Yong KWAK ; Chang Yeol IM
Korean Journal of Hematology 2000;35(3-4):284-286
Multiple myeloma manifestated by necrotizing fasciitis is quite rare. Most of the patients affected with necrotizing fasciitis have some risk factors : Chronic general or local diseases, leukoenia, immunodeficiency diseases, malignancy, and an age of 50 years or more. We have experienced a case of necrotizing fasciitis associated with multiple myeloma presented as jaundice, pain, swelling of right buttock, ab-domiminal distension in 65-year-old man. His general status was improved after incision and drainage of wound and systemic chemotherapy. We recommend that multiple myeloma should be considered if necrotizing fasciitis is diagnosed.
Aged
;
Buttocks
;
Drainage
;
Drug Therapy
;
Fasciitis, Necrotizing*
;
Humans
;
Jaundice
;
Multiple Myeloma*
;
Risk Factors
;
Wounds and Injuries