Cytomegalovirus colitis has been reported infrequently in patients with underlying inflammatory bowel disease, and usually in those who are taking corticosteroid drugs. It has been implicated as a possible exacerbating factor of ulcerative colitis. We experienced a case of cytomegalovirus colitis developed in patient with ulcerative colitis during corticosteroid therapy. So we report the case with a brief review of literatures.
Colitis* ; Colitis, Ulcerative* ; Cytomegalovirus ; Humans ; Inflammatory Bowel Diseases ; Ulcer*

BACKGROUND/AIMS: Experimental studies using porcine non- heart beating donors to ameliorate graft injuries in liver transplantation has been conducted. Recently, it has been reported that cellular calcium may have an important role in ischemic injury, which consists of damage during ischemia and impairment at the time of reperfusion. therefore, it is possible that calcium channel blocker might prevent warm ischemic injury of the graft in liver transplantation when administered to the donor before harvesting and to the recipient at reperfusion. the purpose of this study was to investigate the protective effect of a calcium channel blocker diltiazem (DTZ) on hepatic ischemic injury using a porcine model. METHODS: Twenty pigs weighing 20 to 30 kg were enrolled in this study. Cardiac death was induced by direct cardiac injection of potassium chloride. The perfusion of UW (University of Wisconsin) solution started after 30 min of cardiac arrest. Orthotopic liver transplantation was perforated. Group A (experimental group) was administrated of DTZ at a dose of 70microgram/kg bolus iv injection before hepatic ischemia, perfused of 70microgram/L in UW solution and thereafter infused continuously 70microgram/L in 5% dextrose solution. RESULTS: Two ones death occurred among the ten transplant pigs. 24 hour survival rates were 80%. DTZ administrated group showed the hepatic blood flow and arterial ketone body ratio better compared with untreated controls (p<0.05). In addition, the increase of plasma lactate level was suppressed after ischemia (p<0.05). CONCLUSION: Our results suggest that DTZ has a protective effect on ischemic induced hepatic damage and might be useful in the prevention of primary graft failure caused by warm ischemia in liver transplantation.
Calcium ; Calcium Channels ; Death ; Diltiazem ; Glucose ; Heart ; Heart Arrest ; Humans ; Ischemia ; Lactic Acid ; Liver Transplantation* ; Liver* ; Perfusion ; Plasma ; Potassium Chloride ; Reperfusion ; Survival Rate ; Swine ; Tissue Donors* ; Transplants ; Warm Ischemia

Malignant coloenteric fistula is a rare complication of colon cancer. Colon carcinoma is the most common etiology of this entity. Clinical features are diarrhea, weight loss, anemia and feculent vomiting. The diagnosis is most often made by barium enema examination. The primal therapy is operation. We present a case of a 51-year old male in whom a coloenteric fistula caused by transverse colonic carcinoma. He complained of abdominal pain, diarrhea and dizziness. UGI series demonstrated a fistulous track between colon and small bowel. On abdominal CT examination, a mass involving hepatic flexure of colon with a fistulous tract and metastatic nodules in right lobe of liver were found. Colonoscopy revealed a circumferential mass and the orifice of the fistula. The patient refused operation and expired one month after discharge.
Abdominal Pain ; Anemia ; Barium ; Colon ; Colon, Transverse ; Colonic Neoplasms ; Colonoscopy ; Diagnosis ; Diarrhea ; Dizziness ; Enema ; Fistula* ; Humans ; Liver ; Male ; Middle Aged ; Tomography, X-Ray Computed ; Vomiting ; Weight Loss