1.Neuroleptic Malignant Syndrome in Children and Adolescents : A Review.
Young Sook KWACK ; Jae Sung RYU
Journal of the Korean Academy of Child and Adolescent Psychiatry 2013;24(1):13-20
Neuroleptic malignant syndrome (NMS) is a severe iatrogenic complication of treatment with antipsychotic medication. The aim of this review is to provide the clinical characteristics and treatments of children and adolescents with NMS. Searches were conducted in Medline, Korean studies Information Service System (KISS), and Research Information Service System (RISS). Sixteen case reports and two review articles were selected in Medline, and two Korean cases reported in department of emergency medicine and pediatrics were selected from RISS. Heterogeneous and atypical presentations of NMS were observed in children and adolescents. Some noticeable differences were observed between adult patients and child patients with NMS. In addition, symptom presentations related to atypical antipsychotic agents differed from those of typical ones. In treatment, bromocriptine and benzodiazepine were recommended for management of symptoms. In particular, electroconvulsive therapy (ECT) was a useful treatment option. For prevention and early detection of NMS in children and adolescents, evaluation of risk factors and understanding of diagnostic features of NMS are very important.
Adolescent
;
Adult
;
Antipsychotic Agents
;
Benzodiazepines
;
Bromocriptine
;
Child
;
Electroconvulsive Therapy
;
Emergency Medicine
;
Humans
;
Information Services
;
Neuroleptic Malignant Syndrome
;
Pediatrics
;
Risk Factors
2.Association between the Brain-Derived Neurotropic Factor and Attention Deficit Hyperactivity Disorder.
Na Ri KANG ; Jae Min SONG ; Young Sook KWACK
Journal of the Korean Society of Biological Psychiatry 2018;25(2):21-30
Attention deficit hyperactivity disorder (ADHD) is a common childhood psychiatric disorder. Recently, it has been suggested that brain-derived neurotropic factor (BDNF) may play a role in the pathogenesis of ADHD. Our aim of this review is to understand the physiological functions of BDNF and its potential relationship with ADHD and therapeutic approaches of ADHD. Searches were conducted in Pubmed and Research Information Service System (RISS). In this review, we summarized important literatures for the physiological functions of BDNF in neurodevelopment, change of serum BDNF level in ADHD, association of BDNF polymorphism and ADHD and potential association of treatment of ADHD with serum BDNF level. Further studies are required to more clearly understand the source and the role of BDNF in ADHD and to develop BDNF based-ADHD treatement.
Attention Deficit Disorder with Hyperactivity*
;
Brain-Derived Neurotrophic Factor
;
Information Services
3.Complications and mortality after coronary artery bypass graft surgery: collective review of 61 cases.
Keon Hyon JO ; Jae Chun SHIM ; Kyu Do JO ; Jae Kil PARK ; Chi Kyong KIM ; Young Pil WANG ; Sun Hee LEE ; Moon Sub KWACK ; Se Hwa KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(7):526-531
No abstract available.
Coronary Artery Bypass*
;
Coronary Vessels*
;
Mortality*
4.Comparison of Different Thawing Methods on Cryopreserved Aorta.
Young Min OH ; Sung Bo SIM ; Young Jo SA ; Jae Kil PARK ; Moon Sub KWACK ; Sun Hee LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2004;37(2):113-118
BACKGROUND: The studies on cryopreserved arterial allograft have been focused on cooling methods, pre-treatment, cryoprotectant agents, and preservation temperature. But recently, several studies have reported that thawing methods also play an important role in the occurrence of macroscopic and microscopic cracks. This study was designed to investigate the cell injury after thawing, using a rabbit model to clarify the effect of thawing methods on cryopreserved arteries. MATERIAL AND METHOD: Segments of the rabbit aorta were obtained and divided into 3 groups (n=60) according to whether the specimens were fresh (control, n=20), cryopreserved and rapidly thawed (RT) at 37oC (n=20), or cryopreserved and subjected to controlled, automated slow thawing (ST)(n=20). Cell damage was established using the TUNEL method and the morphological changes were also evaluated. RESULT: In the group that was rapidly thawed, the expression of TUNEL (+) cells increased significantly more than in the slowly thawed group. In addition, the endothelial denudation, microvesicles and edema were significant in the rapidly thawed group compared with those changes in the slowly thawed group. CONCLUSION: Our study suggests that the rapid thawing method may be one of the major causes of cellular damage and delayed rupture in cryopreserved arterial allografts. The expression of TUNEL (+) cells and structural changes were significantly low in the slowly thawed group, which might have contributed to the improvement of graft failure after transplantation.
Allografts
;
Aorta*
;
Arteries
;
Cryopreservation
;
Edema
;
In Situ Nick-End Labeling
;
Rupture
;
Transplants
5.Surgical management of metastatic lung cancer from gestational choriocarcinoma.
Jin Yong JEONG ; Woong CHIN ; Kuhn PARK ; Keon Hyon JO ; Young Pil WANG ; Moon Sub KWACK ; Se Wha KIM ; Hong Kyun LEE ; Jae Keun JUNG
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(10):1005-1010
No abstract available.
Choriocarcinoma*
;
Female
;
Lung Neoplasms*
;
Lung*
;
Pregnancy
6.Surgical treatment of benign lung tumor.
Kuhn PARK ; Deog Gon CHO ; Jae Kil PARK ; Geon Hyon JO ; Young Pil WANG ; Moon Sub KWACK ; Se Wha KIM ; Hong Kyun LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(3):258-270
No abstract available.
Lung*
7.Successful term delivery cases of trans-abdominal cervicoisthmic cerclage performed at more than 18 weeks of gestation.
Eun Joo JOUNG ; Eun Byeol GO ; Jae Young KWACK ; Yong Soon KWON
Obstetrics & Gynecology Science 2016;59(4):319-322
A 38-year-old nulliparous woman was referred to our clinic because of cervical incompetence at 19 weeks of gestation. Trans-abdominal cervicoisthmic cerclage was performed after failure of modified Shirodkar cerclage operation in the patient at 21 weeks of gestation via a laparotomic approach. Another 38-year-old patient, who underwent loop electrosurgical excision procedure conization for treatment of cervical dysplasia 4 years ago, presented for cervical incompetence. At 18 weeks of gestation, we performed trans-abdominal laparotomic cervicoisthmic cerclage without any post-operative complications. During antenatal follow-up, there were no obstetrical co-morbidities and finally she gave birth to a healthy infant at full term by cesarean section. We report two cases of women who underwent trans-abdominal cervicoisthmic cerclage surgery because of cervical incompetence as they were not suitable for transvaginal cervical cerclage. Both patients successfully maintained their pregnancy until full term after undergoing transabdominal cervicoisthmic cerclage at more than 18 weeks of gestation.
Adult
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Cerclage, Cervical
;
Cesarean Section
;
Conization
;
Female
;
Follow-Up Studies
;
Humans
;
Infant
;
Parturition
;
Pregnancy*
;
Uterine Cervical Incompetence
8.Monochorionic twin delivery after conservative surgical treatment of a patient with severe diffuse uterine adenomyosis without uterine rupture.
Jae Young KWACK ; Su Bun JEON ; Keuna KIM ; Soo Jeong LEE ; Yong Soon KWON
Obstetrics & Gynecology Science 2016;59(4):311-315
A 31-year-old nulliparous woman with severe diffuse uterine adenomyosis, which replaced nearly the whole uterine myometrium, visited our hospital due to severe dysmenorrhea, menorrhagia, and a desire to have a baby. The patient had a history of two spontaneous abortions. Laparotomic adenomyomectomy with transient occlusion of uterine arteries (TOUA) was performed safely and the patient tried in vitro fertilization and achieved a intrauterine twin pregnancy after recovery time of the operation. At 31+6 weeks of gestation, a male neonate baby weighing 1,620 g and a male neonate baby weighing 1,480 g were born by transverse lower segment cesarean delivery. There was no complication after the operation. The babies were discharged after receiving routine neonatal intensive care for neonatal respiratory distress syndrome. Adenomyomectomy with TOUA technique would be an option for conservative surgical treatment in patients with severe diffuse whole uterine adenomyosis. This is the first report of twin pregnancy after diffuse whole uterine adenomyomectomy with TOUA.
Abortion, Spontaneous
;
Adenomyosis*
;
Adult
;
Animals
;
Dysmenorrhea
;
Female
;
Fertilization in Vitro
;
Humans
;
Infant, Newborn
;
Intensive Care, Neonatal
;
Male
;
Menorrhagia
;
Mice
;
Myometrium
;
Pregnancy
;
Pregnancy, Twin
;
Respiratory Distress Syndrome, Newborn
;
Twins*
;
Uterine Artery
;
Uterine Rupture*
9.Intraoperative bleeding control during cesarean delivery of complete placenta previa with transient occlusion of uterine arteries.
Ju Hyun KIM ; Eun Ju JOUNG ; Soo Jung LEE ; Jae Young KWACK ; Yong Soon KWON
Obstetrics & Gynecology Science 2015;58(6):522-524
There are few methods to control heavy intra-operative bleeding during cesarean delivery of placenta previa. Transient occlusion of uterine arteries (TOUA) during operation has previously been reported as a quick and safe method to control intra-operative uterine bleeding. We reported 2 cases of cesarean delivery with complete placenta previa in which TOUA was performed to safely reduce intra-operative complication, especially heavy intra-operative bleeding. In the 2 cases, cesarean deliveries were safe and without any complications under the TOUA method. TOUA can be a good method to control heavy intra-operative bleeding during cesarean delivery of complete placenta previa with risk of heavy bleeding.
Hemorrhage*
;
Placenta Previa*
;
Placenta*
;
Uterine Artery*
;
Uterine Hemorrhage
10.Postoperative transesophageal echocardiographic evaluation in patients with cardiac valve replacement.
Keon Hyon JO ; Jin Yong JEONG ; Jae Kul KANG ; Sun Hee LEE ; Young Pil WANG ; Moon Sub KWACK ; Se Wha KIM ; Hong Kyun LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(3):265-270
No abstract available.
Echocardiography*
;
Heart Valves*
;
Humans