No abstract available.
Diagnosis* ; Hepatitis B, Chronic* ; Hepatitis, Chronic*

No abstract available.
Diagnosis* ; Hepatitis B, Chronic* ; Hepatitis, Chronic*

At Orthopaedic Department of Kyung Hee University Hospital, we performed 50 total knee replacement in 32 patients who had suffered from rheumatoid arthritis during the period from Aug. 1982 to Dec. 1987. We studied these cases and compared the results of total knee replacement surgery in preoperative ambulatory patients(group I ) with those in preoperative non-ambulatory patients(group II ). 1. Preoperatively, 19 patients were able to walk, and 13 patients were unable to walk. 2. 7 patients of bilateral TKR(36.8%) were included in group I, and 11 patients (86.9%) in group II. 3. The improvement of range of motion after TKR was greater in group II (34 degrees) and in group I, average postoperative range of motion was similar to the average preoperative ROM. 4. Flexion contracture was more markedly improved in group II. 5. In group I, the average preoperative knee rating score by Hospital for Special Surgery rating system was 38.8 and improved to 93.4 postoperatively. In group II, the average preoperative knee rating score was 27.4 and improved to 85.7 postoperatively. 6. Postoperatively most of the patients were able to walk without support except one cases of infection(group I ) and the other who had severe rheumatoid involvements in other joints (group II ). 7. Preoperative evaluation for involvements of cervical spine and surrounding soft tissue structure was necessary endotracheal anesthesia. 8. There was 2 cases of complications in group I, and 4 cases in group II.
Anesthesia, Endotracheal ; Arthritis ; Arthritis, Rheumatoid ; Arthroplasty, Replacement, Knee ; Contracture ; Humans ; Joints ; Knee ; Range of Motion, Articular ; Spine

The degenerative arthritis following total menisectomy has led to consideration of the need for meniscal transplantation, this study evaluates the morphologic and histologic changes fol lowing fresh meniscal autograft and allograft in therabbits. Transplantation of the medial meniscus was carried out in two groups of 32 rabbits(autograft group=16 rabbits, allograft group=16 rabbits). The morphological and histological changes of the transplanted auto-and allografted menisci and the articular cartilage of the medial femoral and tibial condyle were observed at 2,4,6,8,10,12,22,28 weeks postoperatively. There were no significant differences between auto and allograft groups in gross appearance. Histologically, the fibrous adhesion was noted between grafted meniscus and joint capsule 2 weeks after operation, but complete healing was seen at the suture sites without rejection phenomenon at 6 weeks in both groups. There were prominent inflammatory reactions such as lymphocytes and inflammatory cells infiltration during early postoperative stages(2,4 weeks) only in the allograft group, and more prominent fibrotic reactions in the allograft group than auto-graft group. The results of this study suggest that meniscal allografts are able to adapt to the host tissues, survive within the joint environment, and provide a functional replacement for the removed meniscus, but further studies for graft-host immune response and a method to take the maintenance and deposits of graft must be needed to perform the meniscal allograft in human.
Allografts ; Autografts ; Cartilage, Articular ; Humans ; Joint Capsule ; Joints ; Knee Joint ; Knee ; Lymphocytes ; Menisci, Tibial ; Methods ; Osteoarthritis ; Rabbits ; Sutures ; Transplants

Neonatal acute suppurative parotitis is rare. Staphylococcus aureus is the most common pathogen and antibiotic treatment is the first line therapy. Here, we report a case of acute suppurative parotitis caused by Escherichia coli in a 7­day­old male with febrile sensation, parotid swelling, and purulent discharge from the Stensen duct who was treated successfully with intravenous antibiotics. To the best of our knowledge, this is the first case of neonatal suppurative parotitis caused by E. coli in Korea.

No abstract available.
Humans ; Lupus Erythematosus, Systemic* ; Renal Veins* ; Thrombosis*

The influence of sodium iodate and sodium iodoacetate on the standing potential of rabbits' eyes were investigated with the use of electro-oculography. The electro-oculogram was recorded 1, 3, 5, 24 hours and 5 days after the administrations of the drugs. In order to measure the potential changes induced by illumination, animals were maintained in the dark for 30 minutes and thereafter in the light(illumination 500 lux) for another 30 minutes, during which records were taken every two minutes. In normal eyes, the potential decreased during dark adaptation, and its maximum decrease(about 35%) was attained about 24 minutes. When the eye was exposed to illumination, potential increased, the maximum increase (30%) occurred at 18 minutes. Light peak-dark trough ratio was over 1.4 in all eyes and 1.6 on the average. When the dark-adapted retina was illuminated, EOG amplitude showed a rapid, transient rise followed by a slight fall, with the subsequent light rise. After administration of sodium iodate(20mg./kg.) fall of potential during dark adaptation and rise during light adaptation decreased in its magnitude, accompanied by shortening of dark trough time and light peak time. The light peak-dark trough ratio showed moderate diminution (between 1.2 and 1.3). At the beginning of light adaptation, potential fell transiently followed by continuous slow rise. In eyes treated by sodium iodoacetate (20mg./kg.) potential alterations due to illumination diminished as in eyes treated with sodium iodate. The base-value remained almost unchanged. From these observation, it became clear that the standing potential originated mainly from pigment epithelium, and that the presence of intact visual cells was responsible for alterations induced by level of illumination.
Adaptation, Ocular ; Animals ; Dark Adaptation ; Electrooculography ; Epithelium ; Iodoacetic Acid ; Lighting ; Rabbits* ; Retina ; Sodium

Progressive hepatic fibrosis with development of cirrosis is a feature of chronic liver disease. Assessing fibrosis is important for predicting disease progression and patient management. Liver biopsy is the current gold standard for the diagnosis of liver fibrosis. However, liver biopsy is an invasive procedure. Alternative non-invasive methods have been developed. Serum markers are useful in predicting liver cirrhosis, but accuracy of serum markers is not satisfactory in the assessment of fibrosis. Newly developed transient elastography (Fibroscan) is a non-invasive method of measuring liver stiffness. Fibroscan has been reported to be superior in early detection of cirrhosis to serum markers. Factors influencing it's performance are not fully investigated. The evaluation of new tests should be continued to perform.
Biological Markers/blood ; Chronic Disease ; Disease Progression ; Elasticity Imaging Techniques/methods ; Fibrosis ; Humans ; Hyaluronic Acid/analysis ; Liver/*pathology ; Liver Cirrhosis/*diagnosis/etiology

We report a case of malignant tumor of the stomach showing both carcinoma and sarcoma components in a 47 year-old woman. The resected stomach revealed two tumors which were in different location. The one mass was a 2 x I cm, poorly demarcated tumor at the body, along the lesser curvature and the other was a 6 x 7 cm, well demarcated polypoid tumor with a central depression at cardia of the posterior stomach wall. The tumor at the body was a poorly differentiated adenocarcinoma which showed strong reactivity for CEA. The tumor at the cardia was composed of epithelioid or spindle shaped cells with abundant eosinophilic cytoplasm and revealed 5-6 mitoses per ten high power field. The tumor at the cardia was diagnosed as epithelioid leiomyosarcoma and showed reactivity for vimentin but none for actin, desmin,keratin, and CEA. This is different from the usual carcinosarcoma.
Female ; Humans ; Adenocarcinoma

461 cases of renal biopsy specimens were summerized correlated with their light microscopic and immunofluorescence findings, which obtained from Jan. 1981 to Jul. 1986 at Department of Pathology, Kyung Hee School of Medicine, The results were as follws: 1) The incidence of IgM nephropathy was about 5.8% of the primary glomerulopathy. 2) Sex distribution showed male preponderance with male: female ratio of 1.7:1. 3) Age distribution were 0-9 years 7.4%, 10-19 years 29.6%, 20-29 years 37.0%, 30-39 years 7.4%, 40-49 years 7.4% and 50-59 years 11.1%. 4) The clinical symptoms were gross hematuria 7.4%, microscopic hematuria 59.2%, proteinuria (nonnephrotic) 37.0%, nephrotic syndrome 55.5%, hypertension 7.8% and edema 59.2%. 5) 9 cases (33.3%) had past histories of upper respiratory infections. 6) The distributions of the light microscopic deagnosis were minimal histologic change 11 cases (40.7%), focal glomerulonephritis 7 cases (25.9%), measangial proliferative glomerulonephritis 5 cases (18.5%), focal and segmental glomerulosclerosis 1 case (3.7%) and poststreptococla glomerulonephritis 1 case (3.7%). 7) Immunofluorescence study showed significant diffuse mesangial granular deposits of IgM and C3 in all of the 27 cases. 8) It was demonstrated that in the patients with nephrotic syndrome, the prognosis for the patients with IgM deposition were less favorable than those without IgM deposition.
Female ; Male ; Humans ; Incidence ; Biopsy