No abstract available.
Female* ; Humans ; Neck* ; Urinary Bladder* ; Urinary Incontinence*

No abstract available.
Appendix* ; Cystadenoma, Mucinous* ; Mucins* ; Mucocele* ; Pseudomyxoma Peritonei*

No abstract available.
Appendix* ; Cystadenoma, Mucinous* ; Mucins* ; Mucocele* ; Pseudomyxoma Peritonei*

BACKGROUND AND OBJECTIVES: There have been some reports suggesting that the malignant and benign clinical courses are separable on the basis of HPV subtypes in the sinonasal inverted papilloma. The E6 protein of high risk HPV subtype including types 16 and 18 is known to be associated with p53. The viral E6 protein-p53 complex is responsible for the functional loss of p53 which then becomes immunohistochemically negative. The aim of this study was to determine the prevalence and types of HPV in this neoplasm and evaluate the relationship between expressions of the oncogenes and HPV. MATERIALS AND METHOD: The material was composed of 11 cases of inverted papilloma and 7 cases which were associated with carcinoma. Immunohistochemical staining for p53 was performed. A molecular study of the E6 gene of HPV DNA types 6, 11, 16 and 18 was also performed with separate nest-PCR on squamous cell lesions stainned p53 and papillomatous lesions by use of microdissection technique with paraffin embedded materials. RESULTS: The carcinomatous and dysplastic areas were diffusely positive for p53 in all cases associated with carcinoma, whereas the control group was negative for p53. HPV types 6 and 11, generally known as the lower risk types were presented in the 80% of all cancers and papilloma lesions. A HPV DNA type 18 was solely positive in 2 cases on the p53 overexpressed lesion, associated with carcinoma. CONCLUSION: p53 and HPV may be involved in the pathogenesis of malignant transformation in the inverted papilloma. Therefore, it can be disproved that the HPV subtypes are directly related to either benign or malignant clinical course. However, functional loss of the wild type p53 gene is deeply associated with malignant transformation. In addition to the classical E6 of HPV 16,18-p53, another mechanism could be involved in the functional inactivation of p53.
DNA ; Genes, p53 ; Humans* ; Microdissection ; Oncogenes ; Papilloma* ; Papilloma, Inverted* ; Paraffin ; Prevalence

PURPOSE: To report a patient with symptomatic intraocular pressure (IOP) elevation in an eye with neovascular glaucoma (NVG) during hemodialysis. METHODS: Case report. RESULTS: Recurrent episodes of severe ocular pain and elevated IOP in the NVG eye were noted during hemodialysis in a 29-year-old man. The patient was recently diagnosed at our ophthalmology clinic with NVG due to central retinal vein occlusion. IOP was temporarily controlled after the Ahmed valve implantation. However, after the fibrous membrane developed and occluded the tip of the Ahmed valve, IOP elevation during hemodialysis recurred. Further treatments with intravenous mannitol, oral carbonic anhydrase inhibitor, topical antiglaumatic agents and subconjunctival 5-fluorouracil (5-FU) injections all failed to control relapsing pain and IOP elevation. Eventually, evisceration and hydroxyappatite implantation were performed. CONCLUSIONS: Physicians must be alert to the possibility of IOP elevation in glaucomatous eyes during hemodialysis.
Renal Dialysis/*adverse effects ; Recurrence ; Male ; Kidney Failure, Chronic/complications/*therapy ; Intraocular Pressure/*physiology ; Humans ; Glaucoma, Neovascular/complications/*physiopathology/surgery ; Glaucoma Drainage Implants ; Follow-Up Studies ; Filtering Surgery/instrumentation ; Adult

BACKGROUND AND OBJECTIVES: here have been some studies on the influence of age on the results of vestibular function tests with conflicting results. In influence of age on the results of caloric test, we investigated the sensation of dizziness during caloric test by drawing a correlation between the direction of rotatory sensation and the direction of nystagmus. MATERIALS AND METHODS: We performed monothermal caloric test on 44 healthy adults and divided them into six age groups ranging from 16 and 67. RESULTS: During the test with eyes-closed, 80.23% of patients reported a sensation of self-rotation. Of those, 55.81% expressed the direction of rotation to be the same as that of the fast component of nystagmus, whereas 24.42% expressed the direction to be the same as that of the slow component of nystagmus. During caloric test with eyes-open in light, 59.30% reported a sensation that their surroundings rotated around them. Of those, 43.02% expressed the direction of rotatory sensation to be the same as that of the fast component of nystagmus, whereas 16.28% expressed the direction to be the same as that of the slow component of nystagmus. During caloric test with eyes-closed, most of the subjects felt themselves rotating, whereas most of the subjects felt the outside world were rotating in tests with eyes-open in the light. CONCLUSION: Nystagmus parameters (latency, duration, SPEV at eyes-open and at eyes-closed, visual suppression) did not result in significant differences among different age groups: therefore, we conclude that age doesn't influence the results of caloric tests.
Adult ; Caloric Tests* ; Dizziness* ; Humans ; Sensation* ; Vestibular Function Tests