PURPOSE: The aim of this research was to reduce the interval of breast cancer by reviewing and analyzing its occurrence METHODS: Of the 311 breast cancer patients observed at our clinic between 1998 and 2002, the 14 that had developed breast cancer within the 24 months of their previous screening examination were the subjects of this study. RESULTS: Ductal carcinoma in situ (DCIS) was found in 3 patients revealing changes of, or newly developed, microcalcification. 5 patients, believed to have benign lesion, where follow-up checking was recommended, were later found to have breast cancer. There were 3 failed cases from early diagnosis of cancer due to a dense breast. In 2 cases, the cancer was thought to have progressed due to the lack of an active recommendation for a biopsy, even after suspicious abnormal findings were observed. For all the other cases, the cancer was detected early during routine follow-ups. CONCLUSION: In case of dense breast, intense and thorough examinations including ultrasonography should be recommended because dense breast may prevent the detection of small masses. Especially, it is a fact in Korean women who carry dense breasts in many cases. Even if mass or microcalcification is thought to be benign, a biopsy should be encouraged. For a suspicious lesion, a biopsy should be recommended to a greater extent than the other follow-up measures. Routine screening examinations should be recommended once a year, but can be performed between 6 months and 2 years depending on the patients' age or degree of dense breast.
Biopsy ; Breast Neoplasms* ; Breast* ; Carcinoma, Intraductal, Noninfiltrating ; Early Detection of Cancer ; Female ; Follow-Up Studies ; Humans ; Mass Screening ; Ultrasonography

PURPOSE: To assess the effectiveness and clinical usefulness of prostate biopsy by automated gun biopsy device under the transrectal ultrasonographic guidance, authors analysed the result of biopsy and the patients status after biopsy procedure. METHODS AND MATERIALS: The subjects consisted of 24 patients with prostatic disease. Biopsy instrument was an automated gun biopsy device loaded with an 18 gauze biopsy needle. All the patients were admitted to the hospital. No analgesics was given. All the procedure was performed with the patient in left lateral decubitus. Biopsy was performed at 2-4 different points of the prostate in 22 cases, but recently, six different points were targeted in two patients. RESULTS: Biopsy specimens were sufficient in 21 cases but insufficient in three cases. Histologic examination of biopsy specimens showed that 13 cases were nodular hyperplasia, eight cases were cancerous and three cases were inflammation. There was no clinically significant complication. There was mild to moderate degree of pain in all patients. CONCLUSION: Tansrectal biopsy of the prostate with an automated gun biopsy device under ultrasonographic guidance is considered relatively easy, handy and useful procedure in patients with prostatic disease. The procedure may be performed on the outpatient basis.
Analgesics ; Biopsy* ; Humans ; Hyperplasia ; Inflammation ; Needles ; Outpatients ; Prostate* ; Prostatic Diseases ; Ultrasonography*

It is necessary to confirm disease pathologically even though there are several methods of diagnosis for breast abnormality. Ultrasound guided core needle biopsy (UGCNB) of breast lesions with automated gun is widely accepted as a simple and accurate procedure for avoiding open biopsy. From January 1996 to February 1998, 121 breast lesions of 117 women detected with mammogram, ultrasound, physical examination or any combination were selected. UGCNB was performed in all 121 cases with 7.5 MHz transducer and Manan Pro-mag 2.2 automated biopsy gun (2.2 cm excursion). After local anesthesia, 5-6 cores were obtained through 2mm skin incision site. Lesions categorized as probably benign to highly suspicious were included as indications for core biopsy. 67.5% of the 117 patients were in age thirties and forties. The results of the biopsy were benign in 65 lesions and malignant in 56. 15 patients showing benign results which were contrary to clinical findings and pathologic results, underwent open biopsy. Four patients who had previously been diagnosed as being benign, were found to be malignant (false-negative 3.3%). Primary results of four cases of false negative were intraductal papilloma, severe inflammatory change, atypical ductal hyperplasia, and insufficient sampling, respectively. In case of insufficient sampling resulted from small gauge needle (18G), correct diagnosis was possible in all lesions with large needle (14G). Also excisional biopsy was required in women having intraductal papilloma, severe inflammation and atypical ductal hyperplasia which were difficult to differenciate from malignancy. The UGCNB is excellent biopsy method for multiple breast lesions. The method has demonstrated a 96.7% sensitivity specificity 100%, and positive predictive value (PPV) of 46.3%. We also conclude that UGCNB is proved To be an useful alternative to surgical biopsy on simpler procedure with no adverse cosmetic results.
Anesthesia, Local ; Biopsy ; Biopsy, Large-Core Needle* ; Breast* ; Diagnosis ; Female ; Humans ; Hyperplasia ; Inflammation ; Needles ; Papilloma, Intraductal ; Physical Examination ; Sensitivity and Specificity ; Skin ; Transducers ; Ultrasonography*

PURPOSE: To verify the value of CT in the diagnosis of cirrhosis, CRL ratio was measured in 225 Koreans who had and evidence of cirrhosis both clinically and radiologically. MATERIALS AND METHODS: The mean value of CRL ratio was 0.68+/-0.21 which was significant difterent from the published value of normal person(0.45+/-0.07). The difference of CRL ratio between men and women and that among different age groups were found to be not statistically signficant. RESULTS: CRL ratio of virus- related group(N:149) was 0.64+/-0.18, whereas that of virus-nonrelated group (N=76) was 0.76+/-0.23. There was a statistically significant difference of CRL ratio between virus-related group and virus-nonrelated group. CRL ratio of hepatoma-related group(N:113) was 0.71+/-0.22 whereas that of heparoma-nonrelated group(N:112) was 0.66+/-0.19. There was no statistically significant difference of CRL ratio between hepatoma-related group and hepatoma-nonrelated group. CONCLUSION: Measurement of CRL ratio by CT is a useful method in assessing cirrhosis of the liver.
Diagnosis ; Female ; Fibrosis ; Humans ; Liver Cirrhosis* ; Liver* ; Male

Syphilitic involvement of the stomach often takes the appearance of neoplastic conditions. We describe the radiological findings of syphilitic gastritis. A 36-year-old man was diagnosed with gastric cancer by upper GI and CT, but syphilitic gastritis was confirmed by endoscopy and upper GI series performed after penicillin therapy, We report a case of syphilitic gastritis presented as advanced stomach cancer by clinical, endoscopic and radiological study.
Adult ; Endoscopy ; Gastritis* ; Humans ; Penicillins ; Stomach ; Stomach Neoplasms

Two patients with clinical and biochemical evidences of islet cell hyperfunction underwent percutaneous transhepatic portal and pancreatic vein catheterization and hormone assays. Local step-ups of insulin level in the protal venous system, found in two patients with insulinoma, corresponded to tumor sites at surgery. One patients had single insulinoma and the other had malignant insulinoma and liver metastasis. Percutaneous transhepatic protal and pancreatic vein catheterization with measurement of radioimmunoactive insulin concentration is a safe and reliable method, and may play an important role in the localization of adenoma in patients with hyperinsulinism.
Adenoma ; Adenoma, Islet Cell* ; Catheterization ; Catheters ; Diagnosis* ; Humans ; Hyperinsulinism ; Insulin ; Insulinoma ; Islets of Langerhans* ; Liver ; Methods ; Neoplasm Metastasis ; Veins

Two patients with clinical and biochemical evidences of islet cell hyperfunction underwent percutaneous transhepatic portal and pancreatic vein catheterization and hormone assays. Local step-ups of insulin level in the protal venous system, found in two patients with insulinoma, corresponded to tumor sites at surgery. One patients had single insulinoma and the other had malignant insulinoma and liver metastasis. Percutaneous transhepatic protal and pancreatic vein catheterization with measurement of radioimmunoactive insulin concentration is a safe and reliable method, and may play an important role in the localization of adenoma in patients with hyperinsulinism.
Adenoma ; Adenoma, Islet Cell* ; Catheterization ; Catheters ; Diagnosis* ; Humans ; Hyperinsulinism ; Insulin ; Insulinoma ; Islets of Langerhans* ; Liver ; Methods ; Neoplasm Metastasis ; Veins

No abstract available.
Breast ; Korea

PURPOSE: Computed tomographic(CT), ultrasonographic(US) findings of solid and papillary epithelial neoplasm of the pancreas were correlated with pathologic findings for the better understanding of this disease entity. METHODS AND MATERIALS: A retrospective review of CT and US of 14 cases of solid and papillary epithelial neoplasm of the pancreas was carried out in terms of the margin, internal architecture, caicification and septation, and this was correlated with gross pathologic findings. RESULTS: CT and US findings were well defined round masses consisting of both solid and cystic components. Five cases were cystic, four cases were solid and five cases were mixed. Cystic portion of the tumor represented variable degree of hemorrhagic necrosis. Six cases contained foci of calcification, which were linear, marginal and amorphous. Marginal calcification interfered US examination of the mass in three cases. Internal septurn was demonstrated in four cases on CT, one case on US and three cases on gross specimen. CONCLUSIONS: Our results indicate that calcification and internal septurn were considered as a part of radiologic findings in solid and papillary epithelial neoplasm of the pancreas.
Necrosis ; Neoplasms, Glandular and Epithelial* ; Pancreas* ; Retrospective Studies

No abstract available.
Arthrography* ; Wrist*