1.Effect of the mutation in the carboxyl-terminal processing site of the hepatitis B virus core antigen on the HBeAg secretion.
Seong Kee KIM ; Jae Woo SHIM ; Hyune Mo RHO
Journal of the Korean Society of Virology 1992;22(2):97-104
No abstract available.
Hepatitis B e Antigens*
;
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
2.Infantile Hypertrophic Pyloric Stenosis Treated with Intravenous Atropine Sulfate.
Jae Woo LIM ; Hee Sook SON ; Kye Shik SHIM ; Kyu Chul CHOEH ; Tae Il HAN
Journal of the Korean Pediatric Society 2000;43(6):763-768
PURPOSE: The pharmacologic effect of atropine on HPS can be considered to control pyloric muscle spasm. Therefore, we studied the effects of intravenous atropine sulfate on the clinical course of HPS, and periodically observed the ultrasonographic appearance of the pyloric muscles after atropine treatment. METHODS:From April 1998 to May 1999, 14 infants who were diagnosed with HPS were treated with intravenous atropine sulfate. Intravenous atropine sulfate was administered at an initial dose of 0.04mg/kg/day, which was divided into 8 equal doses. The daily dose was increased by 0.01 mg/kg/day until vomiting was controlled for an entire day while infants received unrestricted oral feeding. Ultrasonographic examinations were performed during hospitalization and repeated at least every 2 months until normalization of pyloric muscles was confirmed. RESULTS: Intravenous atropine was effective in 12 of 14 infants with HPS and the conditions of 9 of them improved. Two infants who were not free from vomiting despite a week of intravenous atropine sulfate treatment underwent pyloromyotomy. A series of ultrasonographic examinations were done after vomiting had improved with intravenous atropine sulfate. The ultrasonographic findings showed good passage of gastric contents through pyloric canals despite thickening of the pyloric muscles. CONCLUSION: Intravenous administration of atropine sulfate is an effective therapy for HPS and can be an alternative to pyloromyotomy. (J Korean Pediatr Soc 2000;43:763-768)
Administration, Intravenous
;
Atropine*
;
Hospitalization
;
Humans
;
Infant
;
Muscles
;
Pyloric Stenosis, Hypertrophic*
;
Spasm
;
Vomiting
3.A Case of Bradycardia-Dependent Complete Atrioventricular(A-V) Block.
Jae Yik LEE ; Young Jo KIM ; Bong Sup SHIM ; Hyun Woo LEE
Yeungnam University Journal of Medicine 1989;6(2):241-245
Induction of A-V block by tachycardia is a well-known phenomenon. But there are few case reports of bradycardia-dependent A-V block. We report a case of bradycardia-dependent A-V block with review of literatures. This patient was a 52-year-old female who complained of dizziness and anterior chest discomfort. Electrocardiographic recording demonstrated complete A-V block. Monitor electrocardiographic recordings during sitting position and after atropine administration demonstrated decrease of degree of block from complete A-V block to first degree A-V block. The occurrence of complete A-V block from bradycardia during supine position suggests a phase 4-dependent block. After a permanent ventricular pacemaker was implanted, the patient recovered and was without symptoms during 12 months follow up.
Atropine
;
Bradycardia
;
Dizziness
;
Electrocardiography
;
Female
;
Follow-Up Studies
;
Humans
;
Middle Aged
;
Supine Position
;
Tachycardia
;
Thorax
4.Treatment of Chronic Osetomyelitis by Saucerization and Gentamicin
Seong Jong LEE ; Dong Woo JANG ; Taik Seon KIM ; Jae Ik SHIM
The Journal of the Korean Orthopaedic Association 1989;24(2):549-556
Chronic osteomyelitis continue to be a therapeutic challenge. The osteomyelitis also implies chronic ischemia of the diseased bone ; thus systemic antibiotic treatment may not be as effective as we want. In 1972, Klemm developed a new procedure to supplement saucerization in the treatment of chronic osteomyelitis, alternative to irrigation and suction-drainage, i.e., Gentamicin-PMMA Beads. The authors analysed 35cases of the chronic osteomyelitis which were admitted and treated by sauceriztion and Gentamicin-PMMA Beads in Department of Orthopaedic Surgery, Korea Veterans Hospital from Aug. 1984 to Jan. 1988.
Gentamicins
;
Hospitals, Veterans
;
Ischemia
;
Korea
;
Osteomyelitis
;
Polymethyl Methacrylate
5.The Clinical Study of Grip and Pinch Strength in Normal Korean Adult
Kwang Suk LEE ; Kyung Jo WOO ; Jae Hak SHIM ; Gyou Hyouk LEE
The Journal of the Korean Orthopaedic Association 1995;30(6):1589-1597
Reliable and valid evaluation of hand strength is of paramount importance in determining the effectiveness of various normative data area needed to interpret evaluation data, to set realistic treatment goals and to assess a patient's ability to return to employment. The primary purpose of this study was to establish normal value of grip and pinch strength for men women in normal Korean adult. A Jamar dynamometer(Hydraulic Hand Dynamometer. PC 5030, USA) was used to measure grip strength and Jamar pinch gauge(Hydraulic Pinch Gauge, PC 5030HPG, USA)was used to measure tip, key and palmar pinch. Two hundreds forty eight male and two hundreds thiry one female adults, aged 20 to 74 years were tested for using standardized positioning with their shoulder adducted and neutrally rotated, elbow flexed at 90。 and the forearm and wrist in neutral position. Right and left hand data were stratified into age groups for both sexes. This stratification provides a means of comparing the scores of individuals to that of normal subjects of the same aged and sex. The following results were obtained; 1. The average grip strength of the dominant hand was highest(43.9±7.3kg)in 3rd decade male group. 2. The average tip pinch strength of the dominant hand was highest in 4th decade(7.3±3.5kg)and 5th decade (7.3±2.4kg) male group. 3. The average key pinch strength of the dominant hand was highest in 5th decade(8.3±2.3 kg)male group. 4. The average palmar pinch strength of the dominant hand was highest in 4th decade(9.6±3.3 kg)male group. 5. A high correlation was seen between grip strength and age, but a low correlation between pinch strength and age. 6. The average grip strength of dominant hand was 5.6% higher than that of nondominant hand in men, and 6.5% higher in women. 7. In pinch strength, palmer pinch strength was highest among the three groups of pinch strength, then key pinch and tip pinch strength in order. 8. The mean scores of the dominant hand were larger than that of the nondominant hand on all hand strength.
Adult
;
Clinical Study
;
Elbow
;
Employment
;
Female
;
Forearm
;
Hand
;
Hand Strength
;
Humans
;
Male
;
Pinch Strength
;
Reference Values
;
Shoulder
;
Wrist
6.Fluoroscopic analysis of lumbar epidural contrast spread after retrograde interlaminar ventral epidural injection (RIVEI).
Ji Seon JEONG ; Jae Chol SHIM ; Jung Pil WOO ; Jae Hang SHIM
Korean Journal of Anesthesiology 2013;65(5):431-437
BACKGROUND: Retrograde interlaminar ventral epidural injection (RIVEI) may hypothetically be more effective if the catheter is placed at the ventrocaudal aspect of the exiting nerve. We tested that hypothesis by measuring ventral and dorsal epidural contrast flow during RIVEI. METHODS: To perform RIVEI, a 17 G Tuohy needle was inserted to access the epidural space. A 19 G epidural catheter was inserted and advanced through the needle, passing in a caudal direction to the lower aspect of the contralateral pedicle. Fluoroscopic images were recorded at 1.5 ml increments of contrast. Based on the images of contrast dispersal, the extent of contrast spreading was assessed in 82 patients. RESULTS: All 82 patients (100%) injected with 3.0 ml contrast medium demonstrated ventral epidural spreading. Mean spreading level from the catheter tip was 2.21 +/- 0.93 with 3.0 ml of contrast. Spreading to the superior aspect of the supra-adjacent intervertebral disc was observed in 67/82 (81.7%) of RIVEIs with 3.0 ml of contrast injected into the ventral epidural space. We found that 3.0 ml of contrast reached the inferior aspect of the infra-adjacent intervertebral disc in 95.1% (78/82) of RIVEIs performed. CONCLUSIONS: Our findings imply that a one-level RIVEI may be sufficient in situations where a two-level injection would currently be used.
Catheters
;
Contrast Media
;
Epidural Space
;
Humans
;
Injections, Epidural*
;
Intervertebral Disc
;
Needles
;
Organic Chemicals
;
Quaternary Ammonium Compounds
7.Anesthetic Management of Emergency Surgery for a Patient with Vascular Ehlers Danlos Syndrome (Type IV): A Case Report
Un Tak WOO ; Woo Jong SHIN ; Jae Hang SHIM ; Woo Jae JEON ; Hyung Joon PARK
Soonchunhyang Medical Science 2023;29(2):49-53
Ehlers-Danlos syndrome (EDS) is a very rare genetic disorder characterized by defects in the production of connective tissue. Among them, vascular EDS is the subtype known to have the worst prognosis due to fragile blood vessels. Accordingly, we would like to report a case report of a patient with vascular EDS with a review of the literature on possible massive transfusion and anesthesiological problems. Patients with vascular EDS have very weak blood vessels and tissues that are easily broken. So there is a high possibility of unexpected massive bleeding during emergency surgery in these patients. Therefore, the anesthesiologist should be fully prepared for the possibility of massive blood loss, keeping in mind the possibility of damage to large blood vessels. The central vein must be secured using ultrasound, sufficient blood and fluids must be prepared, and equipment capable of rapid administration must be perfectly prepared before the start of operation.
8.Ultrasound-guided greater occipital nerve block for patients with occipital headache and short term follow up.
Jae Hang SHIM ; So Young KO ; Mi Rang BANG ; Woo Jae JEON ; Sang Yun CHO ; Jong Hoon YEOM ; Woo Jong SHIN ; Kyoung Hun KIM ; Jae Chol SHIM
Korean Journal of Anesthesiology 2011;61(1):50-54
BACKGROUND: The greater occipital nerve (GON) block has been frequently used for different types of headache, but performed with rough estimates of anatomic landmarks. Our study presents the values of the anatomic parameters and estimates the effectiveness of the ultrasound-guided GON blockade. METHODS: The GON was detected using ultrasound technique and distance from external occipital protuberance (EOP) to GON, from GON to occipital artery and depth from skin to GON was measured in volunteers. Patients with occipital headache were divided into two groups (ultrasound-guided block: group S, conventional blind block: group B) and GON block was performed. The same parameters were measured on group S and VAS scores were assessed at pretreatment, 1 week and 4 weeks after treatment on both groups. RESULTS: The GON had distance of 23.1 +/- 3.4 mm (right) and 20.5 +/- 2.8 mm (left) from EOP to GON. Its depth below the skin was 6.8 +/- 1.5 mm (right) and 7.0 +/- 1.3 mm (left). The distance from GON to occipital artery was 1.5 +/- 0.6 mm (right) and 1.2 +/- 0.6 mm (left) in volunteers. Initial VAS score of group S and group B patients were 6.4 +/- 0.2 and 6.5 +/- 0.2. VAS score of 4 weeks after injection were 2.3 +/- 0.2 on group S and 3.8 +/- 0.3 on group B (P = 0.0003). CONCLUSIONS: The parameters measured in this study should be useful for GON block and ultrasound-guided blockade is likely to be a more effective technique than blind blockade in occipital headache treatment.
Anatomic Landmarks
;
Arteries
;
Follow-Up Studies
;
Headache
;
Humans
;
Nerve Block
;
Skin
9.Anatomical Relationships between Muscles Overlying Distal Transverse Carpal Ligament and Thenar Motor Branch of the Median Nerve.
Midum JEGAL ; Sung Jong WOO ; Hyun Il LEE ; Jae Woo SHIM ; Woo Jin SHIN ; Min Jong PARK
Clinics in Orthopedic Surgery 2018;10(1):89-93
BACKGROUND: The purpose of the current study is to investigate anatomical relationships between the muscle overlying the distal transverse carpal ligament (TCL) and the thenar motor branch of the median nerve. METHODS: Of the 192 wrists that underwent open carpal tunnel release, a muscle belly overlying the TCL was observed on the distal margin of TCL in 25 wrists and ligament exposure could not be achieved without transection of it. We recorded surgical findings of these 25 wrists. The origin of the recurrent motor branch arising from the major median nerve was marked on the axial and coronal section diagrams of the wrist. RESULTS: The presence of muscle overlying the TCL was seen in 25 wrists (21 patients, 13%). The locations of origin were distributed not only on the radial side but anterior or ulnar side of the major median nerve. Abnormal branches originated from the unusual side in 14 cases (56% of those with a muscle overlying the TCL): central-anterior side in eight cases, ulnar-anterior side in five cases, and ulnar side in one case. These anomalous branches were frequently associated with the muscle belly overlying the TCL in our study regardless of the origin site. The branches were prone to cut if careless midline incision along the third web space was performed. Unusual origin and aberrant pathway of the recurrent thenar motor branch were associated with the presence of a muscle overlying the TCL. CONCLUSIONS: A thorough knowledge of the standard and variant anatomy of the muscle belly and recurrent motor branch in the carpal tunnel is fundamental to prevention of complications such as muscle wasting or atrophy by iatrogenic motor branch injury during carpal tunnel release.
Atrophy
;
Carpal Tunnel Syndrome
;
Humans
;
Ligaments*
;
Median Nerve*
;
Muscles*
;
Wrist
10.A cardiovascular collapse occurred in the beach chair position for shoulder arthroscopy under general anesthesia: A case report.
Jihyun SO ; Woo Jong SHIN ; Jae Hang SHIM
Korean Journal of Anesthesiology 2013;64(3):265-267
The occurrence of severe hypotension and bradycardia, following placing to the beach chair position from supine during general anesthesia for repair of tendon injury of the rotator cuff of shoulder in a healthy 50 year-old man was described. The Bezold-Jarisch reflex, which is known to inhibit cardiovascular reflex and composed of three kinds of symptoms such as vasodilation, bradycardia and hypotension, has been reported mainly in peripheral nerve block, and may occur during orthostasis, hypovolemia, hemorrhage, supine inferior vena cava compression in pregnancy, interscalene block for shoulder surgery in the sitting position and so on. The bradycardia and hypotension can be more aggravated when causative elements overlaps each other. Anticholinergics and vasopressor were injected intravenously, and position of the patient was changed to the supine position immediately resulting in a normal vital signs dramatically.
Anesthesia, General
;
Arthroscopy
;
Bradycardia
;
Cholinergic Antagonists
;
Dizziness
;
Hemorrhage
;
Humans
;
Hypotension
;
Hypovolemia
;
Peripheral Nerves
;
Pregnancy
;
Reflex
;
Rotator Cuff
;
Shoulder
;
Supine Position
;
Tendon Injuries
;
Vasodilation
;
Vena Cava, Inferior
;
Vital Signs