1.Effects of Postdialysis Urea Rebound on Dialysis Adequacy in Hemodialysis Patients.
Kun Ho KWON ; Seoung Woo LEE ; Moon Jae KIM
Korean Journal of Nephrology 1998;17(6):926-932
Urea reduction ratio (URR) and Kt/Vurea are objective parameters of dialysis delivery in hemodialysis patients and correlate with nutritional status and patient outcome. URR and Kt/Vurea depend on postdialysis blood urea nitrogen (BUN). In patients with severe postdialysis urea rebound (PDUR), these parameters do not accurately reflect dialysis adequacy. We measured PDUR 30 minutes after dialysis in 26 chronic stable hemodialysis patients. The impact of PDUR on dialysis delivery assessed by URR and Kt/Vurea and the independent factors affecting on PDUR were evaluated. All patients had been dialyzed for 4 hours thrice a week using hemophan membrane. 1) The mean age of patients was 48.6+/-14.8 years and sex ratio was 1:2.3. The mean duration of hemodialysis was 42.7+/-45.0 months. Primary renal diseases were chronic glomerulonephritis 11 (42.3%), diabetic nephropathy 7 (26.9%), and hypertension 4 (15.4%). 2) The mean blood flow was 209.2+/-17.4ml/min. URR, Kt/Vurea, and nPCR using immediate postdialysis BUN were 60+/-7%, 1.13+/-0.21, 1.09+/-0.28g/kg/ day, respectively. The mean recirculation rate was 4.4+/-2.3%. 3)The mean PDUR was 12.2+/-4.6% (range:6-22 %). URR, Kt/Vurea, and nPCR using BUN 30 minutes after dialysis were 55+/-7%, 0.99+/-0.18, and 1.02+/-0.25 g/kg/day, respectively and were significantly lower than those using immediate postdialysis BUN (P<0.05). 4) When the patients were divided according to the degree of PDUR (low PDUR group:<12%, high PDUR group: > or = 12%), high PDUR group was significantly higher than low PDUR group in hematocrit (27.0+/-2.6 vs. 23.5+/-3.6%, P=0.008), URR (64.3+/-5.4 vs. 55.8+/-6.8%, P=0.002), Kt/Vurea (1.26+/-0.17 vs. 1.03+/-0.18, P=0.002), and total recirculation rate (5.6+/-2.7 vs. 3.6+/-1.7%, P=0.05). There were no differences in age, sex, postdialysis body weight, ultrafiltration rate, blood flow, serum albumin, predialysis BUN, creatinine, and nPCR. 5) In multiple regression analysis, the independent factors affecting on PDUR were Kt/Vurea (beta=0.546, P<0.001), recirculation rate (beta=0.422, P<0.001), and hematocrit (beta=0.366, P=0.0017). In conclusion, we think that PDUR should be considered in hemodialysis patients when estimating dialysis delivery, especially if they had high Kt/ Vurea, recirculation rate, and hematocrit.
Blood Urea Nitrogen
;
Body Weight
;
Creatinine
;
Diabetic Nephropathies
;
Dialysis*
;
Glomerulonephritis
;
Hematocrit
;
Humans
;
Hypertension
;
Membranes
;
Nutritional Status
;
Renal Dialysis*
;
Serum Albumin
;
Sex Ratio
;
Ultrafiltration
;
Urea*
2.Clinical Significance ad Asymptomatic Residual Renal Stone Fragments after Shock Wave Lithotripsy.
Jae Hak WOO ; Young Hack KIM ; Chil Hun KWON
Korean Journal of Urology 2000;41(10):1244-1247
No abstract available.
Lithotripsy*
;
Shock*
3.Suprascapular nerve entrapment syndrome by a ganglion, treated with nonoperative method: a case report.
Sang Hoon LEE ; Jin Woo KWON ; Choong Gil LEE ; Jae Hyum PARK ; Kwi Ryun KWON ; Woo Se LEE
The Journal of the Korean Orthopaedic Association 1997;32(3):731-734
Entrapment syndrome of suprascapular nerve by a ganglion has been reported not frequently. We experienced a case of suprascapular nerve entrapment by ganglion which was treated with non-operative treatment, and report it with literature.
Ganglion Cysts*
;
Nerve Compression Syndromes*
4.A Case of Chronic Renal Failure, Caused by IgA Nephropathy Combined with Polycythemia Vera.
Mi Young KWON ; Hee Sub EOM ; Seoung Woo LEE ; Moon Jae KIM ; Tae Sook KIM ; Kun Ho KWON
Korean Journal of Nephrology 1999;18(3):483-487
Patients with chronic renal failure, generally, sufferred from normocytic normochromic anemia caused by decreased level of erythropoietin. But, secondary erythrocytosis has been reported in patients with several renal diseases; renal artery stenosis or throm- bosis, polycystic kidney disease, bilateral hydronephrosis, etc. We report one case of chronic renal failure combined with polycythemia vera. The case was 32 year-old man whose chief complaints were dyspnea, back pain, itching sensation, headache. 6 month ago, the laboratory examination showed only proteinuria and hematuria without deterioration of renal function. The renal function was aggravated with an accelerated course, and bone marrow examination revealed hypercellularity (erythroid predominance), and renal biopsy showed the finding of the end stage of renal disease which may be originated from IgA nephropathy.
Adult
;
Anemia
;
Back Pain
;
Biopsy
;
Bone Marrow Examination
;
Dyspnea
;
Erythropoietin
;
Glomerulonephritis, IGA*
;
Headache
;
Hematuria
;
Humans
;
Hydronephrosis
;
Immunoglobulin A*
;
Kidney Failure, Chronic*
;
Polycystic Kidney Diseases
;
Polycythemia Vera*
;
Polycythemia*
;
Proteinuria
;
Pruritus
;
Renal Artery Obstruction
;
Sensation
5.Magnetization Transfer Ratio of Brain Tissue: Normal Value and Effect of TR/TE.
Tae Sub CHUNG ; Eun Kee JEONG ; Tae Joo JEON ; Duk Jae KIM ; Hyuk Woo KWON
Journal of the Korean Radiological Society 1995;32(4):535-540
PURPOSE: Magnetization transfer imaging(MTI) is a new imaging contrast technique. Our MT pulse sequence is designed as fixed time interval between echo and MT pulse. This study was peformed to evaluate the influence of variations in TR/TE on MTR in T1 weighted image of normal brain tissue on this kind of MT pulse sequence. MATERIALS AND METHODS: Seven healthy volunteers in twenties of age as the objectives, MRI was taken under various TR/TE(TR/TE ;700/14, 650/14, 750/14, 700/20 and 1500/20 msec). MTR was calculated from signal intensities measured at the same point in both pre and post MT images and statisticslly analyzed. The MR imager used in this study was 1.0T Magnetom 42SP(Siemens, Erlangen, Germany) and the parameters of additional MT pulse sequence were offset 1000Hz and bandwidth 250Hz, and posteriorly located to echo with 7.7 msec fixed interval. Offset of this MT pulse was variable. RESULT: In white matter of brain tissue from a normal person, MTR was 34-39%(average 37%) for TR and TE of 700/14 in T1WI and 33-36%(average 35%) for TR/TE of 650/14, and 34-38%(average 35%) for TR/TE of 750/14 which showed no statistical difference. However, in case of 1500/20 of TR/TE, MTR was 26-28%(average 26%) which is statistically significant. With TR/TE of 700/14 as the standrd value, the MTR of gray and white matter were 37% and 29% respectively, showing a definite difference of statistical means. Signal from CSF in ventricles is rarely influenced by MT pulse. CONCLUSION: Conclusively, a subtle variation in TR/TE in T1WI has little influence on MTR but wide range of variation in TR/TE as in proton density image induces significant difference in MTR on this kind of MT pulse sequence. Therefore, the exchangeable usage of MTR data would be possible in narrow range of TR/TE change but difficult in wide range of variation.
Brain*
;
Healthy Volunteers
;
Humans
;
Magnetic Resonance Imaging
;
Protons
;
Reference Values*
6.Cutaneous Metastasis of Esophageal Squamous Cell Carcinoma Mimicking Benign Soft Tissue Tumor.
Jae Woo CHOI ; Soon Hyo KWON ; Jong Soo HONG ; Sang Woong YOUN
Korean Journal of Dermatology 2012;50(9):841-842
No abstract available.
Carcinoma, Squamous Cell
;
Esophageal Neoplasms
;
Neoplasm Metastasis
7.A Study on Left Ventricular Function Evaluation with Radionuclide Angiography in Coronary Artery Disease.
Hyuck Moon KWON ; Hyun Seung KIM ; Hyo Jin PARK ; Jae Soon LEE ; Sung Hyun WOO
Korean Circulation Journal 1987;17(1):55-63
A number of noninvasive technics have been advocated as reflecting left ventricular performance. These methods include systolic time intervals, echocardiography and imaging of the left ventricular chamber with radionuclides during systole and diastole. Radionuclide evaluation of left ventricular function by means of the gamma camera and gating currently appears to be the most reliable noninvasive method for approximating angiographic evaluation of left ventricular performance. Utilizing the radionuclide angiography, we measured the left ventricular function in 19 normal healthy control, 60 patients with coronary artery diseases 7 patients with dilated cardiomyopathy, 5 patients with hypertension. 1) Left ventricular ejection fraction decreased in 12 patients with anterior myocardial infarction (39.9+/-11.6%), 17 patients with inferior myocardial infarction (49.9+/-8.4%) and 7 patients with dilated cardiomyopathy (19.0+/-5.8%), and there was a statistically significant difference compared with 19 normal control group (63.5+/-8.2%)(p<0.005). However there were no statistically significant difference between normal control group, patients with hypertension (58.8+/-7.6%) and patients with angina pectoris (60.1+/-6.5%). 2) Left ventricular ejection fraction decreased in both anterior and inferior myocardial infarction, and there was a statisically significant difference between both groups (p<0.01). All 13 patients with acute myocardial infarction had abnormal LVEF (40.5+/-9.1%) whcih was significantly lower than that of 16 patients with old myolardial infarction (50.1+/-10.5%)(p<0.01).
Angina Pectoris
;
Cardiomyopathy, Dilated
;
Coronary Artery Disease*
;
Coronary Vessels*
;
Diastole
;
Echocardiography
;
Gamma Cameras
;
Humans
;
Hypertension
;
Infarction
;
Inferior Wall Myocardial Infarction
;
Myocardial Infarction
;
Radioisotopes
;
Radionuclide Angiography*
;
Stroke Volume
;
Systole
;
Ventricular Function, Left*
8.Change of Serum K+ Concentration after Injection of Succinylcholine in the Electric Burn Patient .
Sung Woo LEE ; Yeo Song CHO ; Chang Jae KWON
Korean Journal of Anesthesiology 1982;15(2):156-160
Transient hyperkalemia is well known to occur in man following intravenous administration of succinylcholine chloride. We studied the change of the serum potassium concentration after injection of succinylcholine in nonburn patients and electricburn patients, physical status 1 or 2 adopted by the American Society of Anesthesiologists. We compared two groups: Non-burn patient group(Group 1) as control, Electric burn patient group (Group 2) as experimental. The following results were obtained: 1) In non-burn patient group(Group 1) serum potassium concentration was slightly decreased in the 1st, 2nd, 3rd, 4th, 5th, 6th and 10th minute after succinylcholine injection compared with control, but nostatistical significance was noticed in this group. 2) In electric burn patient group (Group 2) serum potassium concentration was maximally increased compared with the controls. Statistical significance was noticed at the 2nd and 3rd minute after succinylcholine injection in this group.
Administration, Intravenous
;
Burns, Electric*
;
Humans
;
Hyperkalemia
;
Potassium
;
Succinylcholine*
9.Induction of Apoptosis by Vibrio vulnificus Cytolysin Through Activation of Caspase-3 in Endothelial Cells.
Byung Hyun PARK ; Kang Beom KWON ; Young Hoon LEE ; Jae Han JANG ; Jin Woo PARK
Journal of Bacteriology and Virology 2001;31(4):333-341
No abstract available.
Apoptosis*
;
Caspase 3*
;
Endothelial Cells*
;
Perforin*
;
Vibrio vulnificus*
;
Vibrio*
10.Surgical management for sacral and presacral tumor.
Young Min WOO ; Yun Kwon JUNG ; Jae Gahb PARK ; Kuk Jin CHOE ; Jin Pok KIM
Journal of the Korean Cancer Association 1992;24(3):443-449
No abstract available.