The investigation of systolic time intervals and hemodynamics was performed in 42 patients with liver cirrhosis by noninvascive methods. The patients were divided into four groups according to the presence or absence of anemia and/or ascites: i.e. group I; cirrhosis without anemia and ascites, group II; cirrhosis with ascites only, group III; cirrhosis with anemia only, and group IV; cirrhosis with ascites and anemia. In the resting state of the patients, the systolic time intervals and hemodynamic data were measured by the high speed simultaneous recordings of electrocardiogram, phonocardiogram, carotid and femoral arterial pulse tracings, and compared with those obtained from 155 normal adult subjects. 1. The pulse were increased considerably in group IV, and diastolic blood pressure was elevated in group II with significance. 2. The stroke volume and cardiac output were increased significantly in group III. 3. The peripheral resistance was reduced particularly in group III, and the volume elasticit coefficient was decreased in group IV. 4. The QS1 interval was prolonged significantly in group II and IV, but QS1 interval corrected by multiple regression equation proposed by our laboratory (illustrated in the text) did not show significant difference compared with that of normal subjects. 5. The left ventricular ejection time(LVET) and total electromechanical systole(QS 2) appeared to be shortened in group II and IV, but the corrected LVET and QS 2 were not different significantly from those of the normal subjects
Adult ; Anemia ; Ascites ; Blood Pressure ; Cardiac Output ; Electrocardiography ; Fibrosis ; Hemodynamics* ; Humans ; Liver Cirrhosis* ; Liver* ; Stroke Volume ; Systole ; Vascular Resistance

The investigation of systolic time intervals and hemodynamics was performed in 42 patients with liver cirrhosis by noninvascive methods. The patients were divided into four groups according to the presence or absence of anemia and/or ascites: i.e. group I; cirrhosis without anemia and ascites, group II; cirrhosis with ascites only, group III; cirrhosis with anemia only, and group IV; cirrhosis with ascites and anemia. In the resting state of the patients, the systolic time intervals and hemodynamic data were measured by the high speed simultaneous recordings of electrocardiogram, phonocardiogram, carotid and femoral arterial pulse tracings, and compared with those obtained from 155 normal adult subjects. 1. The pulse were increased considerably in group IV, and diastolic blood pressure was elevated in group II with significance. 2. The stroke volume and cardiac output were increased significantly in group III. 3. The peripheral resistance was reduced particularly in group III, and the volume elasticit coefficient was decreased in group IV. 4. The QS1 interval was prolonged significantly in group II and IV, but QS1 interval corrected by multiple regression equation proposed by our laboratory (illustrated in the text) did not show significant difference compared with that of normal subjects. 5. The left ventricular ejection time(LVET) and total electromechanical systole(QS 2) appeared to be shortened in group II and IV, but the corrected LVET and QS 2 were not different significantly from those of the normal subjects
Adult ; Anemia ; Ascites ; Blood Pressure ; Cardiac Output ; Electrocardiography ; Fibrosis ; Hemodynamics* ; Humans ; Liver Cirrhosis* ; Liver* ; Stroke Volume ; Systole ; Vascular Resistance

To investigate long term effects of CAPD on the left ventricular function in end-stage renal disease patients, M-mode echocardiographic studies and measurement o fsystolic time intervals were performed in 20 CAPD cases, 28 hemodialysis cases and 29 uremic controls. Compared to the uremic control grup, the patients on CAPD treatment revealed significant improvement of ventricular contractility and reduction of volume. On the other hand in hemodialysis group, even though there was improvement of ventricular contractility, volume control was not adequate. In the systolic time interval measurement, it is postulated that increase of PEP/LVET ratio in CAPD group probably results from reduction of volume(preload) rather than from deranged ventricular function.
Echocardiography ; Hand ; Humans ; Kidney Failure, Chronic* ; Peritoneal Dialysis, Continuous Ambulatory* ; Renal Dialysis* ; Systole ; Ventricular Function ; Ventricular Function, Left

BACKGROUND: Intratumoral fibrosis (ITF) is a frequent histologic finding in solid organ tumors. Renal cell carcinoma (RCC) is a highly vascularized tumor with different shapes and degrees of ITF and inflammation. ITF is a poor prognostic factor, especially in breast cancer, and is related to intratumoral necrosis (ITN) and intratumoral inflammation (ITI). However, the significance of ITF in RCC has not been fully studied. In this study, we evaluate the relationships between ITF and other clinicopathologic parameters associated with RCC prognosis. METHODS: ITF was evaluated in 204 clear cell renal cell carcinoma (CCRCC) specimens according to presence and grade of fibrosis, degree of ITI, and presence of ITN. Lysyl oxidase (LOX) expression in tumor cells was also evaluated with clinicopathologic parameters. RESULTS: Among 204 CCRCC cases, 167 (81.7%) showed ITF, 71 (34.8%) showed ITI, 35 (17.2%) showed ITN, and 111 (54.4%) showed LOX expression. ITF correlated with Fuhrman nuclear grade (p = .046), lymphovascular invasion (LVI) (p = .027), and ITN (p = .036). Patients with ITF had a poor five-year overall survival rate (p = .104). CONCLUSIONS: ITF is related to other poor prognostic factors in CCRCC, such as Fuhrman nuclear grade, ITN, and LVI, but ITF itself had no significant correlation with prognosis of CCRCC.
Breast Neoplasms ; Carcinoma, Renal Cell ; Fibrosis ; Humans ; Inflammation ; Necrosis ; Prognosis ; Protein-Lysine 6-Oxidase ; Survival Rate

A study was performed to develop as a screening tool the Simple Evaluation Questionnaire for Screening the Overweight-type Dietary Pattern in 30 to 49 Year Old Adults. We used the data from the 30 to 49 year old subjects who participated in the three surveys - the health behavior survey, the dietary habit survey and the food intake survey - as the National Health and Nutrition Survey 1998. The 3,598 adults were classified into to two body fatness groups of normal (including underweight) and overweight (including obese) on the basis of their relative body weight (RBW). When comparing variables between the two groups, significant differences were found in gender, education, job, employment status, perceived health status, sadness / depression state, stress level, age, number of diseases, age when overweigh-tedness started, maximum body weight, sleep length, drinking pattern (yes / no), amount of alcoholic drinks, frequency of intoxication or drunkeness, amount of alcoholic drinks when drunk, intensity of exercise, frequency of exercise, exercise duration, skipped meals, small meals and drug supplements. In terms of food intake, there were significant differences in the daily food intake in terms of breakfast, dinner, daily kimchi and dairy products. In terms of mealtimes, we found differences in the amount of cooked rice at breakfast, kimchi at lunch, soup / kuk at dinner, fresh vegetables for snacks, fried foods for snacks between breakfast and lunch, and fruits / juices for snacks between lunch and dinner. After developing questions with indicators and analyzing the indicators by logistic regression analysis three times, we chose 10 questions for a simple evaluation of dietary patterns for the overweight-type category in order to give one point each. Among them we selected two questions to add one additional point and one question to add two additional points. The average scores of the overweight and normal groups, as shown by the developed questionnaire, were 5.97 +/-2.36 and 7.36 +/-2.21, respectively. A score of seven points was selected as the cut-off point. We examined the sensitivity, specificity and positive predictive value of the questionnaire to the results of 67%, 59% and 62%, respectively.
Adipose Tissue ; Adult* ; Alcoholics ; Body Weight ; Breakfast ; Dairy Products ; Depression ; Drinking ; Eating ; Education ; Employment ; Food Habits ; Fruit ; Health Behavior ; Humans ; Logistic Models ; Lunch ; Mass Screening* ; Meals ; Middle Aged* ; Nutrition Surveys ; Overweight ; Sensitivity and Specificity ; Snacks ; Vegetables ; Surveys and Questionnaires

No abstract available.

The objective of this study is to define optimal diagnosis and treatment strategies for patients with urachal anomalies in the pediatric age group. The medical records of 21 children who had undergone surgery for urachal anomalies at Severance Hospital, Yonsei University College of Medicine from January 1990 to April 2005 were reviewed. The subjects included 14 males and 7 females (M:F 2:1). The four types of urachal anomalies confirmed were a urachal cyst in 10 patients (47.6%), a patent urachus in 6 (28.6%), a urachal sinus in 4 (19.0%) and a urachal diverticulum in 1 (4.8%) patient. The most common presenting complaint was umbilical discharge (n = 10, 40.0%), followed by abdominal mass (n = 9, 36.0%). Urachal anomalies were diagnosed by ultrasonography in 18 patients, and 7 of them were additionally examined by computed tomography. The remaining patients were diagnosed solely by surgical exploration. Excision was performed in all patients and was supplemented by partial cystectomy in three. Umbilical discharge was the most common clinical manifestation in our patients, suggesting that ultrasonography should be performed in patients with umbilical discharge to differentiate urachal anomalies. We found the most common anomaly to be the urachal cyst, and all patients were successfully treated by surgical excision.
Urachus/*abnormalities/surgery ; Urachal Cyst/*diagnosis/surgery ; Male ; Infant, Newborn ; Infant ; Humans ; Hospitals, University ; Female ; Child, Preschool ; Child ; Abnormalities/diagnosis/surgery

Kimura's disease is a rare inflammatory disorder of unknown etiology primarily seen in young Asian males. It is characterized by painless subcutaneous masses, blood and tissue eosinophilia, and markedly elevated serum immunoglobulin E (IgE) levels. Clinically, the subcutaneous nodules occur predominantly in the head and neck. However, we report the case of a five-year-old boy presenting with an asymptomatic solitary brown pigmented nodule on the left buttock diagnosed with Kimura's disease. Here we describe the diagnosis and treatment of this unusual case.
Asian Continental Ancestry Group ; Buttocks ; Child, Preschool ; Eosinophilia ; Head ; Humans ; Immunoglobulin E ; Immunoglobulins ; Male ; Neck

BACKGROUND: The peritoneal catheter of the continuous ambulatory peritoneal dialysis(CAPD) is patients' lifeline. A significant number of complications and catheter failures in CAPD are due to mechanical problems. We describe our retrospective experience with CAPD focusing on the rate of catheter displacement and survival according to the site of catheter tip placement in 70 cases of CAPD in Kyunghee University Hospital between November 1994 and February 2000. METHODS: We describe our retrospective experience with CAPD focusing on the rate of catheter displacement and survival according to the site of catheter tip placement in 70 cases of CAPD in Kyunghee University Hospital between November 1994 and February 2000. RESULTS: Among 70 cases of CAPD, 46 cases were right pelvic cavity tip placement and 24 cases were left. Causes of chronic renal failure(CRF) were diabetes mellitus in 29 cases(63%), hypertension in 13 cases (28%), glomerulonephritis in 4 cases(9%) in right pelvic cavity catheter tip placement and diabetes mellitus in 13(54%), hypertension in 10(42%), renal tuberculosis in 1 case(4%) left pelvic cavity catheter tip. There were no difference in causative diseases of CRF between both groups. Incidence of CAPD catheter tip displacement were 17.4%(8/46) at right and 4.2%(1/24) at left catheter(p=0.01). Methods for treatment of displacement were fluoroscopic brushing, laparoscopic manipulation and operation. Of the 9 cases, 5 case were received fluoroscopic brushing, 3 case were laparoscopic manipulation and 1 case was received operation. Other complication were peritonitis, catheter obstruction, hernia, death. Overall survival of catheter were 65%(30/46) at right and 71 %(17/24) at left catheter(p=NS). CONCLUSION: The incidence of CAPD catheter tip displacement was higher with catheter tip at the right pelvis than left(p=0.01). But there is no difference in the catheter survival.
Catheter Obstruction ; Catheters* ; Diabetes Mellitus ; Glomerulonephritis ; Hernia ; Hypertension ; Incidence ; Pelvis ; Peritoneal Dialysis, Continuous Ambulatory ; Peritonitis ; Retrospective Studies ; Tuberculosis, Renal

BACKGROUND: The peritoneal catheter of the continuous ambulatory peritoneal dialysis(CAPD) is patients' lifeline. A significant number of complications and catheter failures in CAPD are due to mechanical problems. We describe our retrospective experience with CAPD focusing on the rate of catheter displacement and survival according to the site of catheter tip placement in 70 cases of CAPD in Kyunghee University Hospital between November 1994 and February 2000. METHODS: We describe our retrospective experience with CAPD focusing on the rate of catheter displacement and survival according to the site of catheter tip placement in 70 cases of CAPD in Kyunghee University Hospital between November 1994 and February 2000. RESULTS: Among 70 cases of CAPD, 46 cases were right pelvic cavity tip placement and 24 cases were left. Causes of chronic renal failure(CRF) were diabetes mellitus in 29 cases(63%), hypertension in 13 cases (28%), glomerulonephritis in 4 cases(9%) in right pelvic cavity catheter tip placement and diabetes mellitus in 13(54%), hypertension in 10(42%), renal tuberculosis in 1 case(4%) left pelvic cavity catheter tip. There were no difference in causative diseases of CRF between both groups. Incidence of CAPD catheter tip displacement were 17.4%(8/46) at right and 4.2%(1/24) at left catheter(p=0.01). Methods for treatment of displacement were fluoroscopic brushing, laparoscopic manipulation and operation. Of the 9 cases, 5 case were received fluoroscopic brushing, 3 case were laparoscopic manipulation and 1 case was received operation. Other complication were peritonitis, catheter obstruction, hernia, death. Overall survival of catheter were 65%(30/46) at right and 71 %(17/24) at left catheter(p=NS). CONCLUSION: The incidence of CAPD catheter tip displacement was higher with catheter tip at the right pelvis than left(p=0.01). But there is no difference in the catheter survival.
Catheter Obstruction ; Catheters* ; Diabetes Mellitus ; Glomerulonephritis ; Hernia ; Hypertension ; Incidence ; Pelvis ; Peritoneal Dialysis, Continuous Ambulatory ; Peritonitis ; Retrospective Studies ; Tuberculosis, Renal