1.Ring-shaped lateral meniscus: a report of two cases.
Journal of the Korean Knee Society 1992;4(1):91-93
No abstract available.
Menisci, Tibial*
2.Restoration of lymphokine-activated killer cell response with indomethacin in tumor bearing mice.
Yeon Sook YUN ; In Sung JUNG ; Jae Soon YUN
Korean Journal of Immunology 1993;15(2):255-261
No abstract available.
Animals
;
Indomethacin*
;
Killer Cells, Lymphokine-Activated*
;
Mice*
3.Correlation between High Blood Pressure and Lipid Profile in School Children.
Young Mi HONG ; Yun Ju KANG ; Sung Jae SUH
Journal of the Korean Pediatric Society 1995;38(12):1645-1652
No abstract available.
Child*
;
Humans
;
Hypertension*
4.Histopathological Changes in Internal Organs atter Administration of Amphotericin B.
Yoon Kee PARK ; Sung Nack LEE ; Jae Yun RO
Korean Journal of Dermatology 1980;18(6):503-509
Vitamin A and its metabolite, retinoic acid, have been recommended for the treatment of psoriasis, ichthyosis, acne vulgaris and Darier's disease which resulted from abaormal regulatory function of keratinocytes. In recent years retinoic acid analogs (retinoids) have been synthesized and shown to be more potent and less toxic than retinoic acid. Since these drugs are therapeutically effective for skin diseases, only with longterm adminiatration of large doses, their toxicities must be seriously considered. The liver is the main site for both storage and excretion of vitamin A and ita derivatives, which may produce injury to the liver and other organs as a result of excess of lysosomal enzyme control. Fatty vacuoles, infiltration of inflammatory cells, focal necrosis, increase in lysosomal enzymes, distension of the RER, decrease in the ribosomes, swelling of the mitochondria, and proliferation of the SER within the hepatocytes have been observed in livers of vitamin A- as well as retinoic acid-treated rats. Its excess may also cause mucous metaplasia of secretory cells of the pancreas. (countinued...)
Acne Vulgaris
;
Amphotericin B*
;
Animals
;
Darier Disease
;
Hepatocytes
;
Ichthyosis
;
Keratinocytes
;
Liver
;
Metaplasia
;
Mitochondria
;
Necrosis
;
Pancreas
;
Psoriasis
;
Rats
;
Ribosomes
;
Skin Diseases
;
Tretinoin
;
Vacuoles
;
Vitamin A
;
Vitamins
5.Complex Method for Correction of Inverted Nipple.
Ki Tae KIM ; Sung Hoon JUNG ; Sung Ho YUN ; Dong Il KIM ; Jae Wook OH
Journal of the Korean Society of Aesthetic Plastic Surgery 1998;4(1):66-71
The inverted nipple presents many problems including both cosmetic and functional aspects and impairment in breast feeding. the histopathologic characters of inverted nipple are that inverted nipple has less fibromuscular tissue than normal nipple and has short lactiferous duct and dense fibrous tissue. Many surgical and non-surgical techniques have been designed for correction of the inverted nipple. But most of these techniques have produced unsatisfactory problems. especially undesirable recurrence is most important problem. We experienced 19 inverted nipples in 12 patients between March 1995 and January 1998. We combined modified Teimourian method, purse-string suture and Z-plasty. and had good result for 3weeks to 30months follow up. This method was effective for correction of the inverted nipple with low recurrence rate and simple techniques.
Breast Feeding
;
Follow-Up Studies
;
Humans
;
Nipples*
;
Recurrence
;
Sutures
6.A Case of Acute Pancreatitis as a Complication of Systemic Lupus Erythematosus.
Jae Sung CHUNG ; Jin Min KONG ; Sun Hee YUN
Korean Journal of Nephrology 1999;18(4):652-655
Systemic lupus erythematosus, an autoimmune disease with multisystem involvement, has been reported to be associated with a number of gastrointestinal complications and symptoms such as nausea, vomiting, and abdominal pain. However, acute pancreatitis only rarely has been reported as a complication of SLE. We report a case of SLE presenting drug unrelated acute pancreatitis as a initial manifestation.
Abdominal Pain
;
Autoimmune Diseases
;
Lupus Erythematosus, Systemic*
;
Nausea
;
Pancreatitis*
;
Vomiting
7.Cellular Schwannoma Arising in a Facial Nerve.
Mee JOO ; Hye Sung KIM ; Yun Kyung KANG ; Hye Kyung LEE ; Jae Young PARK
Korean Journal of Pathology 1997;31(7):688-691
Cellular schwaninoma is a variant of schwannoma, which is characterized by predominance of cellular Antoni A area, presence of mitotic activity, nuclear hyperchromasia, pleomorphism, and absence of Verocay body. These pathologic features often prompted a misdiagnosis of malignancy. However, the clinical outcome has indicated the benignity of the tumor. We have experienced a case of cellular schwannoma arising from right facial nerve with right hemifacial weakness and erosion of mastoid process. Grossly, it was a 3.5 x 3 cm sized and relatively well encapsulated mass with yellowish, friable cut surface. Microscopically, cellular growth with moderate cellular pleomorphism and some mitotic activity (5/40 HPFS, up to 2/HPF) were noted. Immunostaining for S-100 protein showed diffuse strong positive reaction.
Diagnostic Errors
;
Facial Nerve*
;
Mastoid
;
Neurilemmoma*
;
S100 Proteins
8.Outcome of Surgical Angioplasty for Isolated Coronary Ostial Stenosis.
Keon Sik MOON ; Yun Joong KIM ; Jae Sung KIM ; Suk Keun HONG ; Hweung Kon HWANG
Korean Circulation Journal 1999;29(1):46-54
BACKGROUND: Although surgical angioplasty for isolated coronary ostial stenosis is assumend as an alternative approach to CABG, the clinical features of isolated coronary ostial stenosis, postoperative complications and follow-up angiographic results would have not been well studied. METHODS: We retrospectively studied 24 patients (female : male = 20 : 4, mean age 50.0 +/- 12.3 yr) who underwent surgical angioplasty for isolated coronary ostial stenosis using patch ( 22 fresh autologous pericardium, 2 saphenous vein) during the period of March 1990 through February 1998. Repeat coronary angiography (16 patients) and echocardiography (24 patients) were performed. Aortic regurgitation was evaluated semiquantitatively (Grade I - Grade IV). RESULTS: There were 3 deaths after surgical angioplasty. One death was due to acute coronary dissection perioperatively, the second due to low cardiac output syndrome 2 weeks post-surgery, and the third due to traumatic panperitonitis 10 months post-procedure. Angina recurred in 4 patients and the remaning 18 patients were symptom-free. Repeat angiography (19.3 +/- 20.7 Mo) showed widely patent ostium with excellent run-off except 2 patients (1 distal patch stenosis, 1 ostial restenosis in Takayasu's arteritis). The third symptomatic patient was proven to have coronary spasm by ergonovine test. AR increased in the fourth patient (Grade II -> III) with patent ostium. CONCLUSION: Surgical angioplasty may be feasible and alternative operative method to CABG for isolated coronary ostial stenosis. It should however be noted that postop AR can develop and/or increase. Further investigation is needed to evaluate the clinical significance of the AR.
Angiography
;
Angioplasty*
;
Aortic Valve Insufficiency
;
Cardiac Output, Low
;
Constriction, Pathologic*
;
Coronary Angiography
;
Coronary Artery Disease
;
Echocardiography
;
Ergonovine
;
Follow-Up Studies
;
Humans
;
Male
;
Pericardium
;
Postoperative Complications
;
Retrospective Studies
;
Spasm
9.Relationship between HPV Infection and bcl-2 Protein Expression and Apoptosis in Invasive and In Situ Squamous Cell Carcinoma of the Uterine Cervix.
Myoung Ja CHUNG ; Kyu Yun JANG ; Woo Sung MOON ; Myoung Jae KANG ; Dong Geun LEE
Korean Journal of Pathology 1999;33(9):702-708
Human papillomavirus (HPV) 16/18 is a causative agent of uterine cervical carcinoma. HPV 16/18 can alter cell cycle regulation through apoptosis. Bcl-2 is an important regulatory gene of apoptosis. A study was done to evaluate the relation between HPV 16/18 and bcl-2 and apoptosis in 21 cases of carcinoma in-situ (CIS), 5 cases of microinvasive carcinoma and 23 cases of invasive squamous cell carcinoma. HPV 16/18 was detected by hybrid capture system (HCS), bcl-2 protein by immunohistochemical method and apoptosis by using the hematoxylin-eosin stained slide. The results were as follows: Expression of the bcl-2 protein was 43% (9/21) in CIS and 26% (6/23) in invasive carcinoma. Expression of the bcl-2 protein was 42% (5/12) in CIS with HPV 16/18 infection, 44% in CIS without HPV 16/18 infection, 20% (2/10) in invasive carcinoma with HPV 16/18 infection and 31% (4/13) in invasive carcinoma without HPV 16/18 infection. Mean apoptotic index (mAI) was 3.36 in CIS, 5.23 in microinvasive and 6.25 in invasive carcinoma. mAI was 3.66 in CIS with HPV 16/18 infection, 2.86 in CIS without HPV 16/18 infection, 6.18 in invasive carcinoma with HPV 16/18 infection and 6.30 in invasive carcinoma without HPV 16/18 infection. Based on these results, we conclude that there are no correlation between HPV infection and bcl-2, and between HPV infection and apoptosis in invasive and in situ carcinoma of the uterine cervix, and apoptosis is increased according to tumor progression.
Apoptosis*
;
Carcinoma, Squamous Cell*
;
Cell Cycle
;
Cervix Uteri*
;
Female
;
Genes, Regulator
;
Humans
10.Clinical evaluation of lung cancer confirmed to be dead in the post-operative follow-up periods.
Doo Yun LEE ; Hae Kyun KIM ; Hyo Chae PAIK ; Jae Min CHO ; Sung Nok HONG
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(1):86-95
No abstract available.
Follow-Up Studies*
;
Lung Neoplasms*
;
Lung*